Tobacco Smoke Pollution Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=D014028
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Genes

308 genes/proteins interacting with the chemical Tobacco Smoke Pollution from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACAA2 acetyl-CoA acyltransferase 2
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACAT1 acetyl-CoA acetyltransferase 1
ACE2 angiotensin I converting enzyme 2
ACO2 aconitase 2, mitochondrial
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTB actin, beta
ACTG1 actin gamma 1
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGXT alanine-glyoxylate aminotransferase
AGXT2 alanine--glyoxylate aminotransferase 2
AHCY adenosylhomocysteinase
AHR aryl hydrocarbon receptor
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOA aldolase A, fructose-bisphosphate
ALDOB aldolase B, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ANXA1 annexin A1
ANXA2 annexin A2
ANXA5 annexin A5
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOE apolipoprotein E
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASS1 argininosuccinate synthase 1
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCLAF1 BCL2-associated transcription factor 1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C1R complement component 1, r subcomponent
C3 complement component 3
C4B complement component 4B (Chido blood group)
CALB1 calbindin 1, 28kDa
CALR calreticulin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCL11 chemokine (C-C motif) ligand 11
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL22 chemokine (C-C motif) ligand 22
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL7 chemokine (C-C motif) ligand 7
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD86 CD86 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFB complement factor B
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLIC1 chloride intracellular channel 1
CLYBL citrate lyase beta like
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COPE coatomer protein complex, subunit epsilon
COX5A cytochrome c oxidase subunit Va
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CRYL1 crystallin, lambda 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAO D-amino-acid oxidase
DHRS4 dehydrogenase/reductase (SDR family) member 4
ECH1 enoyl CoA hydratase 1, peroxisomal
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENO1 enolase 1, (alpha)
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
ETFDH electron-transferring-flavoprotein dehydrogenase
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FBP1 fructose-1,6-bisphosphatase 1
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FGF9 fibroblast growth factor 9
FGG fibrinogen gamma chain
FHIT fragile histidine triad
FOXO3 forkhead box O3
GALM galactose mutarotase (aldose 1-epimerase)
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA2 GATA binding protein 2
GBAS glioblastoma amplified sequence
GNPDA1 glucosamine-6-phosphate deaminase 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPX1 glutathione peroxidase 1
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSTA1 glutathione S-transferase alpha 1
GSTA3 glutathione S-transferase alpha 3
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HDAC2 histone deacetylase 2
HGD homogentisate 1,2-dioxygenase
HIBADH 3-hydroxyisobutyrate dehydrogenase
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HPD 4-hydroxyphenylpyruvate dioxygenase
HPX hemopexin
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IL10 interleukin 10
IL11 interleukin 11
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
INMT indolethylamine N-methyltransferase
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
IVD isovaleryl-CoA dehydrogenase
KCTD12 potassium channel tetramerization domain containing 12
KHK ketohexokinase (fructokinase)
KLF4 Kruppel-like factor 4 (gut)
KRAS Kirsten rat sarcoma viral oncogene homolog
LCAT lecithin-cholesterol acyltransferase
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MBP myelin basic protein
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLH3 mutL homolog 3
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MPST mercaptopyruvate sulfurtransferase
MSH3 mutS homolog 3
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTPN myotrophin
NAPRT nicotinate phosphoribosyltransferase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGF nerve growth factor (beta polypeptide)
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
OGG1 8-oxoguanine DNA glycosylase
OLA1 Obg-like ATPase 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK7 parkinson protein 7
PCBP1 poly(rC) binding protein 1
PCNA proliferating cell nuclear antigen
PDHB pyruvate dehydrogenase (lipoamide) beta
PDIA3 protein disulfide isomerase family A, member 3
PDIA6 protein disulfide isomerase family A, member 6
PF4 platelet factor 4
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PGLS 6-phosphogluconolactonase
PHB prohibitin
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDX1 peroxiredoxin 1
PRDX6 peroxiredoxin 6
PRKCA protein kinase C, alpha
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTRF polymerase I and transcript release factor
PURA purine-rich element binding protein A
RAB24 RAB24, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPSA ribosomal protein SA
SARDH sarcosine dehydrogenase
SCARB1 scavenger receptor class B, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEPT2 septin 2
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
TCF4 transcription factor 4
TF transferrin
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TPM3 tropomyosin 3
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB7P tubulin, beta 7, pseudogene
UBA1 ubiquitin-like modifier activating enzyme 1
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VDAC2 voltage-dependent anion channel 2
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WNT5A wingless-type MMTV integration site family, member 5A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon