Thrombocytopenia_Megakaryocyte_GSE2527 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2527
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Genes

600 genes differentially expressed during Thrombocytopenia_Megakaryocyte_GSE2527 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ZNF280D zinc finger protein 280D 4.02408
TXLNA taxilin alpha 3.91433
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.91382
SF3B3 splicing factor 3b, subunit 3, 130kDa 3.78548
H1F0 H1 histone family, member 0 3.51417
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 3.49704
PTRH2 peptidyl-tRNA hydrolase 2 3.35908
NCAPH2 non-SMC condensin II complex, subunit H2 3.14052
SLC44A2 solute carrier family 44 (choline transporter), member 2 3.11262
NOP56 NOP56 ribonucleoprotein 3.09477
ZNF445 zinc finger protein 445 3.0532
MCM3 minichromosome maintenance complex component 3 3.03796
RNF169 ring finger protein 169 3.01469
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 2.9846
PCNP PEST proteolytic signal containing nuclear protein 2.98115
EGLN3 egl-9 family hypoxia-inducible factor 3 2.9569
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.91423
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.89598
YY1 YY1 transcription factor 2.83912
SPIN1 spindlin 1 2.8354
PSPH phosphoserine phosphatase 2.79835
C14ORF166 chromosome 14 open reading frame 166 2.74796
NCF1 neutrophil cytosolic factor 1 2.73832
CLK2 CDC-like kinase 2 2.73675
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.52034
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 2.50491
RIPK3 receptor-interacting serine-threonine kinase 3 2.49976
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.45257
SLCO4A1 solute carrier organic anion transporter family, member 4A1 2.44325
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 2.38884
PLXNB3 plexin B3 2.32045
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.26425
PRKG1 protein kinase, cGMP-dependent, type I 2.23157
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.21335
LARP4B La ribonucleoprotein domain family, member 4B 2.21146
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.1675
RBPJ recombination signal binding protein for immunoglobulin kappa J region 2.16061
RGS1 regulator of G-protein signaling 1 2.15997
ERO1L ERO1-like (S. cerevisiae) 2.15824
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 2.13999
ATAD3A ATPase family, AAA domain containing 3A 2.12979
SFSWAP splicing factor, suppressor of white-apricot family 2.07922
ALG10 ALG10, alpha-1,2-glucosyltransferase 2.06821
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 2.05674
BTF3L4 basic transcription factor 3-like 4 2.02784
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.01885
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.98094
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.96753
AMPD2 adenosine monophosphate deaminase 2 1.94389
MTMR9 myotubularin related protein 9 1.94097
ODF2 outer dense fiber of sperm tails 2 1.93484
RCOR2 REST corepressor 2 1.92932
SAP18 Sin3A-associated protein, 18kDa 1.92557
CUEDC1 CUE domain containing 1 1.92453
HSPE1 heat shock 10kDa protein 1 1.89333
SF3A3 splicing factor 3a, subunit 3, 60kDa 1.8508
RARS arginyl-tRNA synthetase 1.83582
PABPN1 poly(A) binding protein, nuclear 1 1.82501
FBXO5 F-box protein 5 1.8149
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.8139
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.80396
SREBF1 sterol regulatory element binding transcription factor 1 1.79773
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 1.79679
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.79609
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.77304
CABLES2 Cdk5 and Abl enzyme substrate 2 1.76569
TRIB3 tribbles pseudokinase 3 1.76306
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1.75946
CYB5R1 cytochrome b5 reductase 1 1.75861
FBL fibrillarin 1.75453
RCC2 regulator of chromosome condensation 2 1.73196
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.70224
NOL8 nucleolar protein 8 1.69394
C14ORF169 chromosome 14 open reading frame 169 1.67554
MED22 mediator complex subunit 22 1.66076
SEC14L2 SEC14-like 2 (S. cerevisiae) 1.65213
SRSF6 serine/arginine-rich splicing factor 6 1.65045
PHGDH phosphoglycerate dehydrogenase 1.63924
KIAA1551 KIAA1551 1.63456
CBX1 chromobox homolog 1 1.62919
SLC25A46 solute carrier family 25, member 46 1.62091
PPP5C protein phosphatase 5, catalytic subunit 1.60154
MED12L mediator complex subunit 12-like 1.59309
EIF3G eukaryotic translation initiation factor 3, subunit G 1.592
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.59016
RPS12 ribosomal protein S12 1.58869
EIF5 eukaryotic translation initiation factor 5 1.58854
KIAA1211L KIAA1211-like 1.56471
UBAP2 ubiquitin associated protein 2 1.5564
TOMM34 translocase of outer mitochondrial membrane 34 1.55572
RHOQ ras homolog family member Q 1.55553
RAP1GAP2 RAP1 GTPase activating protein 2 1.55097
C1ORF174 chromosome 1 open reading frame 174 1.54836
CRLF3 cytokine receptor-like factor 3 1.51853
ZRANB1 zinc finger, RAN-binding domain containing 1 1.51631
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 1.51375
PPP4C protein phosphatase 4, catalytic subunit 1.50294
RWDD4 RWD domain containing 4 1.50294
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1.49965
GPC4 glypican 4 1.47316
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.45956
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.45631
GATA2 GATA binding protein 2 1.45395
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.43604
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.43287
SSRP1 structure specific recognition protein 1 1.42536
EBI3 Epstein-Barr virus induced 3 1.42353
MEGF10 multiple EGF-like-domains 10 1.42113
MED16 mediator complex subunit 16 1.42089
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.40621
GSK3A glycogen synthase kinase 3 alpha 1.39106
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.38783
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 1.38412
FGD3 FYVE, RhoGEF and PH domain containing 3 1.37379
KDSR 3-ketodihydrosphingosine reductase 1.36693
GTPBP10 GTP-binding protein 10 (putative) 1.34806
SARS seryl-tRNA synthetase 1.33758
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 1.33318
CDK1 cyclin-dependent kinase 1 1.3209
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.31613
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.30178
SUB1 SUB1 homolog (S. cerevisiae) 1.29841
FAM98B family with sequence similarity 98, member B 1.27274
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.25226
RNF145 ring finger protein 145 1.23875
RPL7L1 ribosomal protein L7-like 1 1.23326
GALK2 galactokinase 2 1.23221
C1ORF131 chromosome 1 open reading frame 131 1.22925
NAP1L1 nucleosome assembly protein 1-like 1 1.2255
AMOTL2 angiomotin like 2 1.22487
ATM ATM serine/threonine kinase 1.21161
TSSC4 tumor suppressing subtransferable candidate 4 1.20482
C9ORF89 chromosome 9 open reading frame 89 1.20352
SURF1 surfeit 1 1.1983
PLK4 polo-like kinase 4 1.18826
ZNF280C zinc finger protein 280C 1.18369
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.18351
RNF4 ring finger protein 4 1.17851
HBEGF heparin-binding EGF-like growth factor 1.17627
RP9 retinitis pigmentosa 9 (autosomal dominant) 1.16532
SMC5 structural maintenance of chromosomes 5 1.16487
SMYD2 SET and MYND domain containing 2 1.1636
WTAP Wilms tumor 1 associated protein 1.16176
TTC13 tetratricopeptide repeat domain 13 1.16045
UBAC1 UBA domain containing 1 1.14947
FAM111A family with sequence similarity 111, member A 1.1477
UBE2C ubiquitin-conjugating enzyme E2C 1.1428
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 1.13603
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 1.12728
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.12372
ZNF330 zinc finger protein 330 1.12028
ORC6 origin recognition complex, subunit 6 1.11916
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.11896
PENK proenkephalin 1.1165
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.11545
ADIPOR2 adiponectin receptor 2 1.11475
TSPAN3 tetraspanin 3 1.11411
TRIM35 tripartite motif containing 35 1.11218
ARHGAP9 Rho GTPase activating protein 9 1.09829
AHCYL1 adenosylhomocysteinase-like 1 1.09806
FAT1 FAT atypical cadherin 1 1.0962
RBBP4 retinoblastoma binding protein 4 1.08847
GPATCH8 G patch domain containing 8 1.08484
CNOT8 CCR4-NOT transcription complex, subunit 8 1.08385
PYCR1 pyrroline-5-carboxylate reductase 1 1.08199
WDYHV1 WDYHV motif containing 1 1.07916
RRP1B ribosomal RNA processing 1B 1.07868
PAPD7 PAP associated domain containing 7 1.07861
CAND1 cullin-associated and neddylation-dissociated 1 1.07495
C6ORF203 chromosome 6 open reading frame 203 1.06938
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 1.06882
HOMER2 homer scaffolding protein 2 1.06257
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.06245
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.06179
PBX1 pre-B-cell leukemia homeobox 1 1.06073
RPL27 ribosomal protein L27 1.05789
LEPROTL1 leptin receptor overlapping transcript-like 1 1.05602
NINJ1 ninjurin 1 1.05026
LARP1 La ribonucleoprotein domain family, member 1 1.04998
TSPAN4 tetraspanin 4 1.0484
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.03789
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.03778
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.0372
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1.03642
METAP2 methionyl aminopeptidase 2 1.0333
CNOT6L CCR4-NOT transcription complex, subunit 6-like 1.0319
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 1.02757
CAPRIN1 cell cycle associated protein 1 1.0222
TFDP1 transcription factor Dp-1 1.01634
H2AFJ H2A histone family, member J 1.01381
TMEM9 transmembrane protein 9 1.0098
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 1.00914
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.00524
ASF1B anti-silencing function 1B histone chaperone 1.00332
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.00223
EIF3A eukaryotic translation initiation factor 3, subunit A 1.00156
STAT5A signal transducer and activator of transcription 5A 0.994525
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.989915
BEND3 BEN domain containing 3 0.985466
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 0.982987
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.981483
MYO10 myosin X 0.977424
RBBP7 retinoblastoma binding protein 7 0.976759
CMC4 C-x(9)-C motif containing 4 0.971628
TMEM199 transmembrane protein 199 0.970033
PARK7 parkinson protein 7 0.966791
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.964898
THRAP3 thyroid hormone receptor associated protein 3 0.9644
RPS9 ribosomal protein S9 0.96108
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 0.959136
KIAA0368 KIAA0368 0.956674
PRPF8 pre-mRNA processing factor 8 0.951257
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.943313
ALAD aminolevulinate dehydratase 0.942496
FARSB phenylalanyl-tRNA synthetase, beta subunit 0.940415
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 0.937275
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.933908
UBA2 ubiquitin-like modifier activating enzyme 2 0.932636
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 0.931662
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.925288
CDKN2AIPNL CDKN2A interacting protein N-terminal like 0.924585
PDAP1 PDGFA associated protein 1 0.921876
JAG2 jagged 2 0.918453
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.916802
RAB2B RAB2B, member RAS oncogene family 0.915304
SRSF11 serine/arginine-rich splicing factor 11 0.913451
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) 0.91247
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.912092
DMAP1 DNA methyltransferase 1 associated protein 1 0.910748
PHB2 prohibitin 2 0.903755
MAGOHB mago-nashi homolog B (Drosophila) 0.902321
ALS2CL ALS2 C-terminal like 0.901753
TCF12 transcription factor 12 0.897466
LRPPRC leucine-rich pentatricopeptide repeat containing 0.888918
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.879774
ISOC1 isochorismatase domain containing 1 0.876792
ANGPT1 angiopoietin 1 0.874466
PGAM5 phosphoglycerate mutase family member 5 0.873658
GPSM3 G-protein signaling modulator 3 0.870663
TARDBP TAR DNA binding protein 0.868201
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J 0.85706
KCMF1 potassium channel modulatory factor 1 0.85577
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 0.853837
HIRIP3 HIRA interacting protein 3 0.853609
SFR1 SWI5-dependent recombination repair 1 0.852457
YDJC YdjC homolog (bacterial) 0.849615
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 0.846708
RPL15 ribosomal protein L15 0.845237
INTS5 integrator complex subunit 5 0.844319
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.839117
MSH6 mutS homolog 6 0.836486
CTBP2 C-terminal binding protein 2 0.835222
C17ORF85 chromosome 17 open reading frame 85 0.830899
COMMD4 COMM domain containing 4 0.829891
ABHD14A abhydrolase domain containing 14A 0.827112
MRPS33 mitochondrial ribosomal protein S33 0.825335
RPL14 ribosomal protein L14 0.825106
SLC38A1 solute carrier family 38, member 1 0.821366
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.818279
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.817296
ADSS adenylosuccinate synthase 0.81707
GFER growth factor, augmenter of liver regeneration 0.815191
ATP11B ATPase, class VI, type 11B 0.811951
PKNOX1 PBX/knotted 1 homeobox 1 0.810385
PAK1IP1 PAK1 interacting protein 1 0.807881
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.801718
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 0.79729
BMP2K BMP2 inducible kinase 0.796553
STARD4 StAR-related lipid transfer (START) domain containing 4 0.796075
NARS asparaginyl-tRNA synthetase 0.792863
ICA1 islet cell autoantigen 1, 69kDa 0.790038
NEK9 NIMA-related kinase 9 0.789964
RFTN1 raftlin, lipid raft linker 1 0.789879
IGF1R insulin-like growth factor 1 receptor 0.786368
PUS7 pseudouridylate synthase 7 (putative) 0.781196
EMILIN2 elastin microfibril interfacer 2 0.778224
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.777955
DEPDC1B DEP domain containing 1B 0.774994
SERBP1 SERPINE1 mRNA binding protein 1 0.773057
ICT1 immature colon carcinoma transcript 1 0.772686
ZNF655 zinc finger protein 655 0.771635
TRIM11 tripartite motif containing 11 0.76922
ARMCX2 armadillo repeat containing, X-linked 2 0.76786
TTC4 tetratricopeptide repeat domain 4 0.765936
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.764868
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.763602
OSBPL1A oxysterol binding protein-like 1A 0.763376
CDCA4 cell division cycle associated 4 0.759825
ASF1A anti-silencing function 1A histone chaperone 0.757401
BRIX1 BRX1, biogenesis of ribosomes 0.753763
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.753505
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.752678
MMS22L MMS22-like, DNA repair protein 0.752429
GRAMD4 GRAM domain containing 4 0.751596
MTDH metadherin 0.750745
MTAP methylthioadenosine phosphorylase 0.749252
BCAP29 B-cell receptor-associated protein 29 0.749162
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.747164
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.744858
NPAS2 neuronal PAS domain protein 2 0.742537

decreased expression

Symbol Name Standardized Value
APOBR apolipoprotein B receptor -5.01833
SDF2L1 stromal cell-derived factor 2-like 1 -4.98976
CTSH cathepsin H -4.58383
PPIB peptidylprolyl isomerase B (cyclophilin B) -4.04386
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -3.69321
ECM1 extracellular matrix protein 1 -3.60965
CLCN3 chloride channel, voltage-sensitive 3 -3.59971
BAG1 BCL2-associated athanogene -3.52963
PTPRJ protein tyrosine phosphatase, receptor type, J -3.39167
DSTN destrin (actin depolymerizing factor) -3.36284
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -3.25599
PLA2G16 phospholipase A2, group XVI -3.22413
PDCL3 phosducin-like 3 -3.20258
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -3.13299
NDRG1 N-myc downstream regulated 1 -3.12654
LGALS1 lectin, galactoside-binding, soluble, 1 -3.0854
FLNA filamin A, alpha -3.05015
NIPAL3 NIPA-like domain containing 3 -3.04591
MAN1A1 mannosidase, alpha, class 1A, member 1 -3.03626
CTSS cathepsin S -2.96831
MAX MYC associated factor X -2.96424
WDR1 WD repeat domain 1 -2.9217
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.81757
RAB22A RAB22A, member RAS oncogene family -2.78636
C1ORF210 chromosome 1 open reading frame 210 -2.77279
FAM78A family with sequence similarity 78, member A -2.65332
MKL1 megakaryoblastic leukemia (translocation) 1 -2.65093
SCAMP5 secretory carrier membrane protein 5 -2.64903
COTL1 coactosin-like F-actin binding protein 1 -2.57819
ISG20 interferon stimulated exonuclease gene 20kDa -2.53852
RFK riboflavin kinase -2.43353
CST3 cystatin C -2.41929
SURF4 surfeit 4 -2.41534
DUSP1 dual specificity phosphatase 1 -2.3848
SYVN1 synovial apoptosis inhibitor 1, synoviolin -2.37959
AMD1 adenosylmethionine decarboxylase 1 -2.37297
NCOA4 nuclear receptor coactivator 4 -2.36728
TIMP3 TIMP metallopeptidase inhibitor 3 -2.35852
SRP19 signal recognition particle 19kDa -2.35613
RHOB ras homolog family member B -2.35446
ZSWIM6 zinc finger, SWIM-type containing 6 -2.33002
C3AR1 complement component 3a receptor 1 -2.32734
PPP1R15A protein phosphatase 1, regulatory subunit 15A -2.28472
CNN2 calponin 2 -2.26624
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -2.26134
STON2 stonin 2 -2.23108
RASA3 RAS p21 protein activator 3 -2.22001
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.2136
IL6ST interleukin 6 signal transducer -2.21153
PROS1 protein S (alpha) -2.20415
SAMD9L sterile alpha motif domain containing 9-like -2.20364
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.202
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -2.19711
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -2.19597
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.18829
IGF1 insulin-like growth factor 1 (somatomedin C) -2.16336
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -2.15711
SQLE squalene epoxidase -2.13979
LPL lipoprotein lipase -2.08161
PYGL phosphorylase, glycogen, liver -2.04415
CMA1 chymase 1, mast cell -2.04362
SERTAD2 SERTA domain containing 2 -2.04281
COL18A1 collagen, type XVIII, alpha 1 -2.01486
GYPC glycophorin C (Gerbich blood group) -2.01369
CREG1 cellular repressor of E1A-stimulated genes 1 -2.00047
JUNB jun B proto-oncogene -1.98521
NAGA N-acetylgalactosaminidase, alpha- -1.939
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -1.93581
ACOT7 acyl-CoA thioesterase 7 -1.9357
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.93044
SMG5 SMG5 nonsense mediated mRNA decay factor -1.91903
NDRG4 NDRG family member 4 -1.91003
GADD45G growth arrest and DNA-damage-inducible, gamma -1.87497
TALDO1 transaldolase 1 -1.86312
UBE2F ubiquitin-conjugating enzyme E2F (putative) -1.85203
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -1.83566
TSPO translocator protein (18kDa) -1.8147
CKB creatine kinase, brain -1.81071
ACTN4 actinin, alpha 4 -1.80275
TOR1AIP1 torsin A interacting protein 1 -1.80133
SLAMF1 signaling lymphocytic activation molecule family member 1 -1.79947
NPC1 Niemann-Pick disease, type C1 -1.79423
GLTP glycolipid transfer protein -1.75323
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -1.75267
CSK c-src tyrosine kinase -1.73332
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -1.72735
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) -1.71634
C4ORF27 chromosome 4 open reading frame 27 -1.71429
UBASH3B ubiquitin associated and SH3 domain containing B -1.70696
PARVB parvin, beta -1.70403
NPY neuropeptide Y -1.69577
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.67358
ILK integrin-linked kinase -1.65385
IL1B interleukin 1, beta -1.64847
CD48 CD48 molecule -1.63509
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -1.62341
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -1.61975
EHD1 EH-domain containing 1 -1.58215
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.5806
FAM126A family with sequence similarity 126, member A -1.57526
CNST consortin, connexin sorting protein -1.56568
ADCY9 adenylate cyclase 9 -1.56457
HACD1 3-hydroxyacyl-CoA dehydratase 1 -1.56148
ADD1 adducin 1 (alpha) -1.55958
TAOK3 TAO kinase 3 -1.55829
SGPL1 sphingosine-1-phosphate lyase 1 -1.55681
SRXN1 sulfiredoxin 1 -1.54476
USO1 USO1 vesicle transport factor -1.5272
IRGM immunity-related GTPase family, M -1.52638
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -1.51919
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -1.51713
FAM46C family with sequence similarity 46, member C -1.51483
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -1.4778
ADCY6 adenylate cyclase 6 -1.47649
EPOR erythropoietin receptor -1.47616
BLVRB biliverdin reductase B -1.47287
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) -1.46737
GBP7 guanylate binding protein 7 -1.46284
SCAMP2 secretory carrier membrane protein 2 -1.46283
MAP2K3 mitogen-activated protein kinase kinase 3 -1.46205
TUBB1 tubulin, beta 1 class VI -1.44828
VAT1 vesicle amine transport 1 -1.43752
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.43664
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.42972
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) -1.40655
CLIC4 chloride intracellular channel 4 -1.39695
GATAD1 GATA zinc finger domain containing 1 -1.39411
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -1.37612
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -1.37449
RNF19B ring finger protein 19B -1.37118
SEPP1 selenoprotein P, plasma, 1 -1.36746
HHEX hematopoietically expressed homeobox -1.3588
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -1.34621
HDAC5 histone deacetylase 5 -1.34451
ARMCX1 armadillo repeat containing, X-linked 1 -1.33706
CD28 CD28 molecule -1.33433
DRAXIN dorsal inhibitory axon guidance protein -1.31546
PDLIM7 PDZ and LIM domain 7 (enigma) -1.31515
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -1.31272
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -1.31248
PPP6C protein phosphatase 6, catalytic subunit -1.31195
F5 coagulation factor V (proaccelerin, labile factor) -1.3112
MCM3AP minichromosome maintenance complex component 3 associated protein -1.30536
UBA7 ubiquitin-like modifier activating enzyme 7 -1.2925
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -1.28364
RPIA ribose 5-phosphate isomerase A -1.28298
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -1.28071
STX11 syntaxin 11 -1.27961
GP1BA glycoprotein Ib (platelet), alpha polypeptide -1.2745
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -1.27234
ISCA1 iron-sulfur cluster assembly 1 -1.26578
TMEM41B transmembrane protein 41B -1.2626
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha -1.26258
RSAD2 radical S-adenosyl methionine domain containing 2 -1.25556
HPS4 Hermansky-Pudlak syndrome 4 -1.24119
MOB1B MOB kinase activator 1B -1.23876
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -1.23716
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -1.22914
NGDN neuroguidin, EIF4E binding protein -1.21853
TMEM106A transmembrane protein 106A -1.21807
NUCB1 nucleobindin 1 -1.20264
PARP9 poly (ADP-ribose) polymerase family, member 9 -1.20041
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.19719
JAK2 Janus kinase 2 -1.19271
GBX2 gastrulation brain homeobox 2 -1.1755
ARHGAP18 Rho GTPase activating protein 18 -1.17524
GPR137 G protein-coupled receptor 137 -1.16734
ASB1 ankyrin repeat and SOCS box containing 1 -1.15953
TRIOBP TRIO and F-actin binding protein -1.15715
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.15646
SIRPA signal-regulatory protein alpha -1.14284
EMILIN1 elastin microfibril interfacer 1 -1.14199
RANBP10 RAN binding protein 10 -1.12221
SEPW1 selenoprotein W, 1 -1.11607
CST7 cystatin F (leukocystatin) -1.10751
ABHD12 abhydrolase domain containing 12 -1.10661
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.10404
CAPN2 calpain 2, (m/II) large subunit -1.1012
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.10115
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -1.10054
HSPH1 heat shock 105kDa/110kDa protein 1 -1.0983
MANF mesencephalic astrocyte-derived neurotrophic factor -1.09453
PDGFB platelet-derived growth factor beta polypeptide -1.08724
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -1.08634
FAM109B family with sequence similarity 109, member B -1.08428
CSTB cystatin B (stefin B) -1.08099
INTS12 integrator complex subunit 12 -1.07855
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.06959
TSPAN9 tetraspanin 9 -1.06785
MPEG1 macrophage expressed 1 -1.06102
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.05781
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.05689
DAP death-associated protein -1.05601
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -1.05317
PLTP phospholipid transfer protein -1.05097
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) -1.04857
RAB21 RAB21, member RAS oncogene family -1.04594
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -1.04381
OTUD7B OTU deubiquitinase 7B -1.04347
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -1.04016
RGS10 regulator of G-protein signaling 10 -1.03961
SRC SRC proto-oncogene, non-receptor tyrosine kinase -1.03508
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -1.03471
F2RL3 coagulation factor II (thrombin) receptor-like 3 -1.03267
EMB embigin -1.03117
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -1.02884
MXD1 MAX dimerization protein 1 -1.01754
GSTA5 glutathione S-transferase alpha 5 -1.01608
STK38L serine/threonine kinase 38 like -1.01533
ZFP36 ZFP36 ring finger protein -1.00955
AACS acetoacetyl-CoA synthetase -0.997499
PECAM1 platelet/endothelial cell adhesion molecule 1 -0.995965
GLMP glycosylated lysosomal membrane protein -0.993195
SCARB1 scavenger receptor class B, member 1 -0.991243
FERMT3 fermitin family member 3 -0.991063
EVI2B ecotropic viral integration site 2B -0.989411
GRB10 growth factor receptor-bound protein 10 -0.985658
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.985044
GRN granulin -0.982029
RAP2C RAP2C, member of RAS oncogene family -0.981554
VWF von Willebrand factor -0.979463
RIN3 Ras and Rab interactor 3 -0.975206
TAPBP TAP binding protein (tapasin) -0.973592
CAPN3 calpain 3, (p94) -0.96845
ACOT9 acyl-CoA thioesterase 9 -0.965459
SRI sorcin -0.9626
NCOA3 nuclear receptor coactivator 3 -0.960839
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.959329
PIAS3 protein inhibitor of activated STAT, 3 -0.955029
DDT D-dopachrome tautomerase -0.944074
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -0.943437
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -0.941884
USP18 ubiquitin specific peptidase 18 -0.940902
CLU clusterin -0.940604
CORO1A coronin, actin binding protein, 1A -0.940223
THBS1 thrombospondin 1 -0.939872
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) -0.93731
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -0.93679
FER fer (fps/fes related) tyrosine kinase -0.93093
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -0.924162
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -0.919447
CGRRF1 cell growth regulator with ring finger domain 1 -0.919423
DGKA diacylglycerol kinase, alpha 80kDa -0.916763
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -0.912346
TEC tec protein tyrosine kinase -0.910619
MFGE8 milk fat globule-EGF factor 8 protein -0.909242
STX7 syntaxin 7 -0.908268
MRPS36 mitochondrial ribosomal protein S36 -0.907394
IL2RG interleukin 2 receptor, gamma -0.905981
MOB3A MOB kinase activator 3A -0.905143
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.899706
PLD3 phospholipase D family, member 3 -0.896412
NCF2 neutrophil cytosolic factor 2 -0.895715
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -0.894459
SNX16 sorting nexin 16 -0.890413
PNP purine nucleoside phosphorylase -0.888912
THEMIS2 thymocyte selection associated family member 2 -0.877863
MYH9 myosin, heavy chain 9, non-muscle -0.87766
GATA1 GATA binding protein 1 (globin transcription factor 1) -0.8765
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.874533
DPCD deleted in primary ciliary dyskinesia homolog (mouse) -0.872482
DOCK5 dedicator of cytokinesis 5 -0.871475
S100A4 S100 calcium binding protein A4 -0.870764
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.870343
FRMD4B FERM domain containing 4B -0.869361
OPTN optineurin -0.869243
CPA3 carboxypeptidase A3 (mast cell) -0.867791
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.863646
CYBB cytochrome b-245, beta polypeptide -0.863117
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -0.85767
OCIAD2 OCIA domain containing 2 -0.856097
TBXAS1 thromboxane A synthase 1 (platelet) -0.853808
G6PD glucose-6-phosphate dehydrogenase -0.849035
EDF1 endothelial differentiation-related factor 1 -0.84894
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.845985
C19ORF43 chromosome 19 open reading frame 43 -0.844594
RRAGA Ras-related GTP binding A -0.843408
MAGT1 magnesium transporter 1 -0.840947
TMUB2 transmembrane and ubiquitin-like domain containing 2 -0.839445
GMFG glia maturation factor, gamma -0.837963
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -0.837031
NAGLU N-acetylglucosaminidase, alpha -0.83701
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.833292
TWF1 twinfilin actin binding protein 1 -0.83259
LPXN leupaxin -0.832438
TRAPPC2 trafficking protein particle complex 2 -0.830742
DUSP23 dual specificity phosphatase 23 -0.830617
GDE1 glycerophosphodiester phosphodiesterase 1 -0.829903
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.829019
FBXO2 F-box protein 2 -0.827273
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B -0.824137
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.816999
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -0.814787
AP2M1 adaptor-related protein complex 2, mu 1 subunit -0.813591
OMA1 OMA1 zinc metallopeptidase -0.805892
FLOT1 flotillin 1 -0.805327
TESC tescalcin -0.80391
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.802227
GLRX glutaredoxin (thioltransferase) -0.797628
LYN LYN proto-oncogene, Src family tyrosine kinase -0.790192