Thrombocytopenia Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A blood platelet disease characterized by low a platelet count in the blood. (Human Disease Ontology, DOID_1588)
Similar Terms
Downloads & Tools

Genes

80 genes associated with the Thrombocytopenia phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AOX1 aldehyde oxidase 1
CCL2 chemokine (C-C motif) ligand 2
CD209 CD209 molecule
CDA cytidine deaminase
CYCS cytochrome c, somatic
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCK deoxycytidine kinase
DDRGK1 DDRGK domain containing 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHFR dihydrofolate reductase
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYD dihydropyrimidine dehydrogenase
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP9 glycoprotein IX (platelet)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MGMT O-6-methylguanine-DNA methyltransferase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYH9 myosin, heavy chain 9, non-muscle
NQO1 NAD(P)H dehydrogenase, quinone 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRJ protein tyrosine phosphatase, receptor type, J
PWAR1 Prader Willi/Angelman region RNA 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TUBB1 tubulin, beta 1 class VI
TYK2 tyrosine kinase 2
TYMS thymidylate synthetase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VWF von Willebrand factor