TCR signaling in naïve CD8+ T cells Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
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Genes

51 proteins participating in the TCR signaling in naïve CD8+ T cells pathway from the PID Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
B2M beta-2-microglobulin
BCL10 B-cell CLL/lymphoma 10
CARD11 caspase recruitment domain family, member 11
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD247 CD247 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CHUK conserved helix-loop-helix ubiquitous kinase
CSK c-src tyrosine kinase
FYN FYN proto-oncogene, Src family tyrosine kinase
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HLA-A major histocompatibility complex, class I, A
HRAS Harvey rat sarcoma viral oncogene homolog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
ORAI1 ORAI calcium release-activated calcium modulator 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PLCG1 phospholipase C, gamma 1
PRF1 perforin 1 (pore forming protein)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
RAP1A RAP1A, member of RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
SOS1 son of sevenless homolog 1 (Drosophila)
STIM1 stromal interaction molecule 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VAV1 vav 1 guanine nucleotide exchange factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa