Systemic Inflammatory Response Syndrome Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

30 genes associated with the Systemic Inflammatory Response Syndrome phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
CALCA calcitonin-related polypeptide alpha
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL8 chemokine (C-X-C motif) ligand 8
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
HMGB1 high mobility group box 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
IRAK4 interleukin-1 receptor-associated kinase 4
LMAN1 lectin, mannose-binding, 1
LTA lymphotoxin alpha
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
PI3 peptidase inhibitor 3, skin-derived
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor