Stress, Psychological Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

269 genes associated with the Stress, Psychological phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADCY5 adenylate cyclase 5
ADCY7 adenylate cyclase 7
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADD3 adducin 3 (gamma)
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADH6 alcohol dehydrogenase 6 (class V)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTRAP angiotensin II receptor-associated protein
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOE apolipoprotein E
ARRB2 arrestin, beta 2
AVP arginine vasopressin
AVPR1A arginine vasopressin receptor 1A
AVPR1B arginine vasopressin receptor 1B
BDNF brain-derived neurotrophic factor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CAPN10 calpain 10
CARTPT CART prepropeptide
CAT catalase
CCK cholecystokinin
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCNL1 cyclin L1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CHRM5 cholinergic receptor, muscarinic 5
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCNKB chloride channel, voltage-sensitive Kb
CLOCK clock circadian regulator
CMA1 chymase 1, mast cell
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CSNK1E casein kinase 1, epsilon
CYBA cytochrome b-245, alpha polypeptide
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DCDC2 doublecortin domain containing 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DISC1 disrupted in schizophrenia 1
DMPK dystrophia myotonica-protein kinase
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DYX1C1 dyslexia susceptibility 1 candidate 1
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRB endothelin receptor type B
EGF epidermal growth factor
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FAAH fatty acid amide hydrolase
FASN fatty acid synthase
FEV FEV (ETS oncogene family)
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FTO fat mass and obesity associated
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GLP1R glucagon-like peptide 1 receptor
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GLRB glycine receptor, beta
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPHN gephyrin
GPX1 glutathione peroxidase 1
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSS glutathione synthetase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GSTM4 glutathione S-transferase mu 4
GSTM5 glutathione S-transferase mu 5
HCRT hypocretin (orexin) neuropeptide precursor
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INS insulin
INSR insulin receptor
JUN jun proto-oncogene
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KIAA0319 KIAA0319
KLK1 kallikrein 1
LDLR low density lipoprotein receptor
LEKR1 leucine, glutamate and lysine rich 1
LEP leptin
LEPR leptin receptor
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MLH1 mutL homolog 1
MPDZ multiple PDZ domain protein
MPO myeloperoxidase
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NGF nerve growth factor (beta polypeptide)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPSR1 neuropeptide S receptor 1
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
NPY5R neuropeptide Y receptor Y5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTSR1 neurotensin receptor 1 (high affinity)
NTSR2 neurotensin receptor 2
ODC1 ornithine decarboxylase 1
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PDYN prodynorphin
PENK proenkephalin
PER1 period circadian clock 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PLXNA2 plexin A2
PNOC prepronociceptin
POMC proopiomelanocortin
PON1 paraoxonase 1
PON2 paraoxonase 2
PON3 paraoxonase 3
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKCE protein kinase C, epsilon
REN renin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RORA RAR-related orphan receptor A
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1D sodium channel, non voltage gated 1 delta subunit
SELE selectin E
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
TAC1 tachykinin, precursor 1
TH tyrosine hydroxylase
TNF tumor necrosis factor
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TXNRD2 thioredoxin reductase 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
USF1 upstream transcription factor 1
WNK1 WNK lysine deficient protein kinase 1
WNK4 WNK lysine deficient protein kinase 4
XBP1 X-box binding protein 1