Stereotypic Movement Disorder Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A specific developmental disorder that is characterized by repeated, rhythmic, purposeless movements or activities such as head banging, nail biting, or body rocking. (Human Disease Ontology, DOID_2303)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D019956
Similar Terms
Downloads & Tools

Genes

148 genes/proteins associated with the disease Stereotypic Movement Disorder from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CRH corticotropin releasing hormone 2.88009
TRH thyrotropin-releasing hormone 2.88009
MEF2C myocyte enhancer factor 2C 2.88009
DRD2 dopamine receptor D2 2.37508
BDNF brain-derived neurotrophic factor 2.2738
PRL prolactin 2.25124
FOS FBJ murine osteosarcoma viral oncogene homolog 2.17326
TH tyrosine hydroxylase 2.12519
DRD1 dopamine receptor D1 2.10941
DRD3 dopamine receptor D3 1.98439
MAPK1 mitogen-activated protein kinase 1 1.92721
PENK proenkephalin 1.84906
NPY neuropeptide Y 1.81866
MAPK3 mitogen-activated protein kinase 3 1.81665
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.79637
CAT catalase 1.78759
TAC1 tachykinin, precursor 1 1.77762
ARC activity-regulated cytoskeleton-associated protein 1.77024
GFAP glial fibrillary acidic protein 1.76752
MAOB monoamine oxidase B 1.75699
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.755
DRD4 dopamine receptor D4 1.75122
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.74984
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.74681
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.73878
SOD1 superoxide dismutase 1, soluble 1.71524
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.65227
PVALB parvalbumin 1.64595
EGR1 early growth response 1 1.64033
CREB1 cAMP responsive element binding protein 1 1.63586
BAX BCL2-associated X protein 1.63272
JUNB jun B proto-oncogene 1.63205
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.60944
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.60734
HOMER1 homer scaffolding protein 1 1.59873
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.59638
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.58018
BCL2 B-cell CLL/lymphoma 2 1.57924
COMT catechol-O-methyltransferase 1.55182
GAL galanin/GMAP prepropeptide 1.54937
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.54669
GSK3A glycogen synthase kinase 3 alpha 1.54159
GSK3B glycogen synthase kinase 3 beta 1.52036
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.52036
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.51986
OPRM1 opioid receptor, mu 1 1.5108
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.49278
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.49071
ADORA2A adenosine A2a receptor 1.49045
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.4889
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.4766
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.47452
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.47115
OXT oxytocin/neurophysin I prepropeptide 1.46568
JUN jun proto-oncogene 1.44599
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.44193
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.43021
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.43021
CNR1 cannabinoid receptor 1 (brain) 1.3827
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.37132
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.36933
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.36361
GRM5 glutamate receptor, metabotropic 5 1.34547
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.32221
TNF tumor necrosis factor 1.31927
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.30269
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.30269
PRKCE protein kinase C, epsilon 1.29905
FGF2 fibroblast growth factor 2 (basic) 1.28241
MAP2 microtubule-associated protein 2 1.27626
CCK cholecystokinin 1.26825
DUSP1 dual specificity phosphatase 1 1.26576
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.26545
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.26021
MAOA monoamine oxidase A 1.25868
INHA inhibin, alpha 1.23552
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.22436
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.22306
IL1B interleukin 1, beta 1.21304
GRM1 glutamate receptor, metabotropic 1 1.21206
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.2013
CCKBR cholecystokinin B receptor 1.20097
MBP myelin basic protein 1.19835
POMC proopiomelanocortin 1.19704
HPCA hippocalcin 1.19672
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.19379
PLCD4 phospholipase C, delta 4 1.18981
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.18326
EGR2 early growth response 2 1.18126
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.17728
RELN reelin 1.17366
MAPK8 mitogen-activated protein kinase 8 1.169
RGS2 regulator of G-protein signaling 2 1.1617
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.15933
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.15357
DLG4 discs, large homolog 4 (Drosophila) 1.14781
GRIK2 glutamate receptor, ionotropic, kainate 2 1.14781
SOD2 superoxide dismutase 2, mitochondrial 1.13518
RGS4 regulator of G-protein signaling 4 1.13415
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.12872
ELK1 ELK1, member of ETS oncogene family 1.12872
NTS neurotensin 1.12357
PLP1 proteolipid protein 1 1.11673
NUPR1 nuclear protein, transcriptional regulator, 1 1.1136
FAS Fas cell surface death receptor 1.11186
FOSL2 FOS-like antigen 2 1.11011
KCNIP3 Kv channel interacting protein 3, calsenilin 1.10838
GDNF glial cell derived neurotrophic factor 1.10769
LDHB lactate dehydrogenase B 1.10493
S100B S100 calcium binding protein B 1.09716
PDYN prodynorphin 1.09506
GAP43 growth associated protein 43 1.09262
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.0919
FOSL1 FOS-like antigen 1 1.08478
DDIT3 DNA-damage-inducible transcript 3 1.08442
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.08126
IL6 interleukin 6 1.07983
PRKCD protein kinase C, delta 1.07732
PRKCG protein kinase C, gamma 1.07696
INS insulin 1.07589
GPX1 glutathione peroxidase 1 1.07376
CKB creatine kinase, brain 1.07128
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.06917
FXYD7 FXYD domain containing ion transport regulator 7 1.06881
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.06844
NOS1 nitric oxide synthase 1 (neuronal) 1.06552
CDK5 cyclin-dependent kinase 5 1.06479
CHRM1 cholinergic receptor, muscarinic 1 1.05163
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.04941
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.04868
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 1.04501
MAP2K1 mitogen-activated protein kinase kinase 1 1.04014
VEGFA vascular endothelial growth factor A 1.03604
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.03308
AVP arginine vasopressin 1.03271
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.02971
JUND jun D proto-oncogene 1.02262
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.02114
SYT5 synaptotagmin V 1.02114
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.02077
LIN7C lin-7 homolog C (C. elegans) 1.0204
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.0204
PARP1 poly (ADP-ribose) polymerase 1 1.02003
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.01776
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.01512
SYT11 synaptotagmin XI 1.01437
GPR88 G protein-coupled receptor 88 1.01324
SREBF1 sterol regulatory element binding transcription factor 1 1.01174