Squamous cell carcinoma_Lung Tissue_GSE1987 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1987
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Genes

600 genes differentially expressed during Squamous cell carcinoma_Lung Tissue_GSE1987 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PPIA peptidylprolyl isomerase A (cyclophilin A) 5.98128
RPS18 ribosomal protein S18 4.77751
RPL11 ribosomal protein L11 3.91236
HMGN2 high mobility group nucleosomal binding domain 2 3.89477
RPS27 ribosomal protein S27 3.44118
RPL31 ribosomal protein L31 3.3711
RPS24 ribosomal protein S24 2.9701
RPS12 ribosomal protein S12 2.96996
RPL37 ribosomal protein L37 2.50031
RPLP0 ribosomal protein, large, P0 2.0929
RPS8 ribosomal protein S8 1.8408
RPS3A ribosomal protein S3A 1.65724
RBM3 RNA binding motif (RNP1, RRM) protein 3 1.51062
PSAP prosaposin 1.32601
RPL38 ribosomal protein L38 1.22903
RPL27 ribosomal protein L27 1.22543
RPL37A ribosomal protein L37a 1.2192
NACA nascent polypeptide-associated complex alpha subunit 1.21779
RHOA ras homolog family member A 1.06533
RPL27A ribosomal protein L27a 1.04813
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.02054
RPL34 ribosomal protein L34 1.00225
ESR1 estrogen receptor 1 0.916744
CSTB cystatin B (stefin B) 0.894682
PRSS22 protease, serine, 22 0.805102
DGCR2 DiGeorge syndrome critical region gene 2 0.802097
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.756043
LAMP1 lysosomal-associated membrane protein 1 0.747131
NPEPPS aminopeptidase puromycin sensitive 0.722384
EIF3D eukaryotic translation initiation factor 3, subunit D 0.710867
BTN2A1 butyrophilin, subfamily 2, member A1 0.701779
FLG filaggrin 0.694553
SPP1 secreted phosphoprotein 1 0.690386
PRDX4 peroxiredoxin 4 0.681444
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.677312
RPL19 ribosomal protein L19 0.671623
ATOX1 antioxidant 1 copper chaperone 0.665082
AARS alanyl-tRNA synthetase 0.664473
PDIA4 protein disulfide isomerase family A, member 4 0.661137
PRDX1 peroxiredoxin 1 0.658814
AIM2 absent in melanoma 2 0.652328
SZT2 seizure threshold 2 homolog (mouse) 0.651954
PARN poly(A)-specific ribonuclease 0.647754
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.640171
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.638314
RPL15 ribosomal protein L15 0.636132
SIN3B SIN3 transcription regulator family member B 0.62604
CD6 CD6 molecule 0.617404
RBM4B RNA binding motif protein 4B 0.614362
SETDB1 SET domain, bifurcated 1 0.613325
AP3M2 adaptor-related protein complex 3, mu 2 subunit 0.61281
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.60712
METAP1 methionyl aminopeptidase 1 0.602861
ADRBK1 adrenergic, beta, receptor kinase 1 0.598679
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.598645
COL10A1 collagen, type X, alpha 1 0.597358
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.592016
GOLGA1 golgin A1 0.589721
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.586538
GNPDA1 glucosamine-6-phosphate deaminase 1 0.579446
ZMYM3 zinc finger, MYM-type 3 0.575403
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.572072
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 0.571601
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.571146
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.567215
RPS16 ribosomal protein S16 0.560227
NSF N-ethylmaleimide-sensitive factor 0.556134
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.555743
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.555119
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.553589
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.551904
EED embryonic ectoderm development 0.550238
TTLL5 tubulin tyrosine ligase-like family member 5 0.546377
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.546276
SURF2 surfeit 2 0.542613
SLC38A6 solute carrier family 38, member 6 0.542534
PARP2 poly (ADP-ribose) polymerase 2 0.541503
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.537762
CREBZF CREB/ATF bZIP transcription factor 0.53595
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.535545
PARP1 poly (ADP-ribose) polymerase 1 0.534354
RPS26 ribosomal protein S26 0.533925
CCNE1 cyclin E1 0.533628
LEF1 lymphoid enhancer-binding factor 1 0.529535
ZNF142 zinc finger protein 142 0.526083
IL4 interleukin 4 0.524773
SSR4 signal sequence receptor, delta 0.523313
C11ORF80 chromosome 11 open reading frame 80 0.51789
ADAM28 ADAM metallopeptidase domain 28 0.514003
FANCG Fanconi anemia, complementation group G 0.512519
BUB3 BUB3 mitotic checkpoint protein 0.512289
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.510799
RPL41 ribosomal protein L41 0.510064
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.509915
XBP1 X-box binding protein 1 0.509107
STMN1 stathmin 1 0.507633
ZNF133 zinc finger protein 133 0.50683
CLSTN3 calsyntenin 3 0.505736
IGKC immunoglobulin kappa constant 0.505584
ZNF7 zinc finger protein 7 0.504999
AMPD2 adenosine monophosphate deaminase 2 0.50414
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.503637
FEN1 flap structure-specific endonuclease 1 0.502519
ZNF862 zinc finger protein 862 0.50233
CACTIN cactin, spliceosome C complex subunit 0.501366
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.500912
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.500785
BRD8 bromodomain containing 8 0.496152
ZFP36L1 ZFP36 ring finger protein-like 1 0.496063
DCAF11 DDB1 and CUL4 associated factor 11 0.494204
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.490929
GUSBP11 glucuronidase, beta pseudogene 11 0.487529
TTC22 tetratricopeptide repeat domain 22 0.486987
FGF12 fibroblast growth factor 12 0.486305
JTB jumping translocation breakpoint 0.483006
BGN biglycan 0.482576
AKAP17A A kinase (PRKA) anchor protein 17A 0.482526
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.480427
SIT1 signaling threshold regulating transmembrane adaptor 1 0.479886
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 0.47973
RPS21 ribosomal protein S21 0.479597
TNK2 tyrosine kinase, non-receptor, 2 0.47767
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.476053
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.475801
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.475577
ASB4 ankyrin repeat and SOCS box containing 4 0.474477
ZNF623 zinc finger protein 623 0.472162
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.471803
TEAD3 TEA domain family member 3 0.471711
STARD5 StAR-related lipid transfer (START) domain containing 5 0.469267
CLSTN1 calsyntenin 1 0.468052
USP46 ubiquitin specific peptidase 46 0.466522
RPL13 ribosomal protein L13 0.465601
ACP2 acid phosphatase 2, lysosomal 0.464388
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 0.463828
KNTC1 kinetochore associated 1 0.463331
THUMPD1 THUMP domain containing 1 0.462958
RXRB retinoid X receptor, beta 0.46231
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.461555
BRCA2 breast cancer 2, early onset 0.459776
RUNX1 runt-related transcription factor 1 0.459392
ELF4 E74-like factor 4 (ets domain transcription factor) 0.458692
TMEM63A transmembrane protein 63A 0.458368
AGGF1 angiogenic factor with G patch and FHA domains 1 0.45533
RAE1 ribonucleic acid export 1 0.455212
MYDGF myeloid-derived growth factor 0.455047
ACTA2 actin, alpha 2, smooth muscle, aorta 0.454631
ADAM8 ADAM metallopeptidase domain 8 0.4539
SNRPC small nuclear ribonucleoprotein polypeptide C 0.453456
TBP TATA box binding protein 0.449831
DGKB diacylglycerol kinase, beta 90kDa 0.448475
TUBA1B tubulin, alpha 1b 0.442227
BLM Bloom syndrome, RecQ helicase-like 0.441214
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.440728
MAGED1 melanoma antigen family D1 0.439099
UCKL1 uridine-cytidine kinase 1-like 1 0.43902
NECAB3 N-terminal EF-hand calcium binding protein 3 0.436904
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.436792
EIF3H eukaryotic translation initiation factor 3, subunit H 0.435969
ACTL8 actin-like 8 0.432454
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.431225
GANAB glucosidase, alpha; neutral AB 0.43113
TRADD TNFRSF1A-associated via death domain 0.430321
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 0.429999
TMED2 transmembrane emp24 domain trafficking protein 2 0.427939
RAD9A RAD9 homolog A (S. pombe) 0.427391
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.427084
EIF4A2 eukaryotic translation initiation factor 4A2 0.426453
DIDO1 death inducer-obliterator 1 0.425777
SLC25A42 solute carrier family 25, member 42 0.425358
SCYL3 SCY1-like 3 (S. cerevisiae) 0.424749
ORC5 origin recognition complex, subunit 5 0.42445
RTCA RNA 3'-terminal phosphate cyclase 0.423925
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 0.423623
PYCR1 pyrroline-5-carboxylate reductase 1 0.422605
FUCA1 fucosidase, alpha-L- 1, tissue 0.420936
IFT20 intraflagellar transport 20 0.418204
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.417892
RPL36A ribosomal protein L36a 0.417871
VRK1 vaccinia related kinase 1 0.417454
OFD1 oral-facial-digital syndrome 1 0.415824
FZD2 frizzled class receptor 2 0.413548
RAB30 RAB30, member RAS oncogene family 0.412956
DEPDC5 DEP domain containing 5 0.412855
NFX1 nuclear transcription factor, X-box binding 1 0.412228
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.410557
WIPI2 WD repeat domain, phosphoinositide interacting 2 0.410537
FKBP4 FK506 binding protein 4, 59kDa 0.409888
FRMPD4 FERM and PDZ domain containing 4 0.409792
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.409556
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 0.408429
NUP133 nucleoporin 133kDa 0.407211
CRYBB3 crystallin, beta B3 0.40707
HLA-DOB major histocompatibility complex, class II, DO beta 0.406539
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.405493
RPS15A ribosomal protein S15a 0.40498
RNF187 ring finger protein 187 0.404626
CTCF CCCTC-binding factor (zinc finger protein) 0.404211
METTL21B methyltransferase like 21B 0.403868
TMED9 transmembrane emp24 protein transport domain containing 9 0.403802
NPM3 nucleophosmin/nucleoplasmin 3 0.403503
IFITM3 interferon induced transmembrane protein 3 0.403377
AKR1D1 aldo-keto reductase family 1, member D1 0.402205
GARS glycyl-tRNA synthetase 0.401982
HTRA2 HtrA serine peptidase 2 0.401547
TTLL12 tubulin tyrosine ligase-like family member 12 0.401236
CUL7 cullin 7 0.401145
DGKA diacylglycerol kinase, alpha 80kDa 0.40083
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.400315
MDC1 mediator of DNA-damage checkpoint 1 0.4001
COG5 component of oligomeric golgi complex 5 0.399995
TUBB7P tubulin, beta 7, pseudogene 0.399739
PRCC papillary renal cell carcinoma (translocation-associated) 0.399433
SEZ6L seizure related 6 homolog (mouse)-like 0.39917
DPP4 dipeptidyl-peptidase 4 0.398224
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.397714
TPH1 tryptophan hydroxylase 1 0.397483
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 0.39641
CFDP1 craniofacial development protein 1 0.396043
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.395093
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.394495
ODF1 outer dense fiber of sperm tails 1 0.394065
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.393178
ERCC5 excision repair cross-complementation group 5 0.392524
RPS9 ribosomal protein S9 0.392269
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.391914
NEUROD2 neuronal differentiation 2 0.391556
MCM2 minichromosome maintenance complex component 2 0.391185
IRF9 interferon regulatory factor 9 0.38971
SYN1 synapsin I 0.389627
DPF2 D4, zinc and double PHD fingers family 2 0.388889
P4HB prolyl 4-hydroxylase, beta polypeptide 0.387926
KIAA0907 KIAA0907 0.387694
SETD1A SET domain containing 1A 0.387438
FADD Fas (TNFRSF6)-associated via death domain 0.387321
NUPL2 nucleoporin like 2 0.387181
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.386871
HOXC11 homeobox C11 0.385404
MELK maternal embryonic leucine zipper kinase 0.385243
CTSA cathepsin A 0.384708
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.383912
GLMN glomulin, FKBP associated protein 0.383209
BLNK B-cell linker 0.38245
RPS7 ribosomal protein S7 0.381728
RAB13 RAB13, member RAS oncogene family 0.380614
PCGF1 polycomb group ring finger 1 0.380485
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.380455
DDB2 damage-specific DNA binding protein 2, 48kDa 0.38037
TERF2IP telomeric repeat binding factor 2, interacting protein 0.380196
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.379096
IRF5 interferon regulatory factor 5 0.378253
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.375796
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.375512
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.375388
B2M beta-2-microglobulin 0.374892
NFRKB nuclear factor related to kappaB binding protein 0.373997
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.372823
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.372314
C5ORF15 chromosome 5 open reading frame 15 0.372253
GAK cyclin G associated kinase 0.371631
DDT D-dopachrome tautomerase 0.370542
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.370404
NEK9 NIMA-related kinase 9 0.369458
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.369381
TOMM34 translocase of outer mitochondrial membrane 34 0.368369
HLA-DMB major histocompatibility complex, class II, DM beta 0.367886
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.367414
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.366122
TOP2A topoisomerase (DNA) II alpha 170kDa 0.366109
CDH16 cadherin 16, KSP-cadherin 0.366084
RPS28 ribosomal protein S28 0.365394
CXCR6 chemokine (C-X-C motif) receptor 6 0.365372
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.365296
BIRC5 baculoviral IAP repeat containing 5 0.365094
COL2A1 collagen, type II, alpha 1 0.365055
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.364129
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 0.363778
TRIM23 tripartite motif containing 23 0.363712
POU2F1 POU class 2 homeobox 1 0.362781
RPP14 ribonuclease P/MRP 14kDa subunit 0.362632
PSD4 pleckstrin and Sec7 domain containing 4 0.362612
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 0.362469
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.361686
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.36164
MPHOSPH9 M-phase phosphoprotein 9 0.361506
ATG14 autophagy related 14 0.361224
HSPA8 heat shock 70kDa protein 8 0.360838
FDXR ferredoxin reductase 0.360332
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.360169
AAK1 AP2 associated kinase 1 0.360111
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.360103
DIEXF digestive organ expansion factor homolog (zebrafish) 0.359867
MTG1 mitochondrial ribosome-associated GTPase 1 0.359465
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.358823
PTK6 protein tyrosine kinase 6 0.358709
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.358429
RGS10 regulator of G-protein signaling 10 0.358259
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.358052
TENM4 teneurin transmembrane protein 4 0.357731
IGHM immunoglobulin heavy constant mu 0.357587

decreased expression

Symbol Name Standardized Value
RPL32 ribosomal protein L32 -1.74141
IFNA4 interferon, alpha 4 -1.4793
LDLR low density lipoprotein receptor -1.14058
EHD1 EH-domain containing 1 -0.944235
MPRIP myosin phosphatase Rho interacting protein -0.922212
PODXL podocalyxin-like -0.899546
TACC1 transforming, acidic coiled-coil containing protein 1 -0.875277
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -0.873905
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -0.871384
SRY sex determining region Y -0.867815
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -0.865805
NTNG1 netrin G1 -0.849537
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.778479
GRK5 G protein-coupled receptor kinase 5 -0.76103
CDH5 cadherin 5, type 2 (vascular endothelium) -0.758413
DCC DCC netrin 1 receptor -0.75255
CFD complement factor D (adipsin) -0.746289
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.740414
CLK3 CDC-like kinase 3 -0.732981
CYB5R3 cytochrome b5 reductase 3 -0.729976
REEP5 receptor accessory protein 5 -0.69612
NEBL nebulette -0.687546
FAM189A2 family with sequence similarity 189, member A2 -0.687176
SORBS3 sorbin and SH3 domain containing 3 -0.687032
MACF1 microtubule-actin crosslinking factor 1 -0.685049
LRRC32 leucine rich repeat containing 32 -0.675199
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -0.675182
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -0.673001
KANK3 KN motif and ankyrin repeat domains 3 -0.671252
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.670819
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -0.657588
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.655523
RRAGA Ras-related GTP binding A -0.654495
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.650376
WNT1 wingless-type MMTV integration site family, member 1 -0.648385
EIF1 eukaryotic translation initiation factor 1 -0.646294
PTCRA pre T-cell antigen receptor alpha -0.63308
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.629848
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -0.628831
TNNT2 troponin T type 2 (cardiac) -0.620721
PDLIM1 PDZ and LIM domain 1 -0.616402
TYRP1 tyrosinase-related protein 1 -0.607262
NOTCH4 notch 4 -0.603882
MAOB monoamine oxidase B -0.588598
RHO rhodopsin -0.587803
PEA15 phosphoprotein enriched in astrocytes 15 -0.582703
URM1 ubiquitin related modifier 1 -0.582189
TRAK2 trafficking protein, kinesin binding 2 -0.580558
ACVRL1 activin A receptor type II-like 1 -0.579148
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.578171
STX5 syntaxin 5 -0.577915
MEF2A myocyte enhancer factor 2A -0.575377
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -0.57473
CRYGA crystallin, gamma A -0.55873
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.556504
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -0.551977
CEP104 centrosomal protein 104kDa -0.551926
RPL5 ribosomal protein L5 -0.549122
SRPX sushi-repeat containing protein, X-linked -0.549081
TAGLN2 transgelin 2 -0.548476
MTTP microsomal triglyceride transfer protein -0.548127
MME membrane metallo-endopeptidase -0.538471
SLC25A44 solute carrier family 25, member 44 -0.538165
CDC42 cell division cycle 42 -0.53725
TCP11L1 t-complex 11, testis-specific-like 1 -0.534912
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -0.532701
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.531683
TMEM115 transmembrane protein 115 -0.529741
NUP98 nucleoporin 98kDa -0.529618
USP12 ubiquitin specific peptidase 12 -0.528724
PRM1 protamine 1 -0.527057
MAPK3 mitogen-activated protein kinase 3 -0.526349
HAVCR1 hepatitis A virus cellular receptor 1 -0.525566
PA2G4 proliferation-associated 2G4, 38kDa -0.52535
TLX1 T-cell leukemia homeobox 1 -0.519581
ITPKB inositol-trisphosphate 3-kinase B -0.516938
BCHE butyrylcholinesterase -0.516131
MFN2 mitofusin 2 -0.515637
STX2 syntaxin 2 -0.514222
ATP7A ATPase, Cu++ transporting, alpha polypeptide -0.512523
ETF1 eukaryotic translation termination factor 1 -0.507191
SOX13 SRY (sex determining region Y)-box 13 -0.507011
STIM1 stromal interaction molecule 1 -0.503464
CTBP2 C-terminal binding protein 2 -0.50249
MAPK7 mitogen-activated protein kinase 7 -0.502358
EMP2 epithelial membrane protein 2 -0.499465
TP53I11 tumor protein p53 inducible protein 11 -0.498153
PCBP1 poly(rC) binding protein 1 -0.495352
FOLR3 folate receptor 3 (gamma) -0.493897
FAM127A family with sequence similarity 127, member A -0.491167
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -0.490596
FRY furry homolog (Drosophila) -0.49028
MAP4 microtubule-associated protein 4 -0.487915
TJP2 tight junction protein 2 -0.485869
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -0.4831
LRRN3 leucine rich repeat neuronal 3 -0.481425
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -0.47793
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -0.476261
AKR1C4 aldo-keto reductase family 1, member C4 -0.475322
FHL1 four and a half LIM domains 1 -0.474485
VSTM4 V-set and transmembrane domain containing 4 -0.472978
GPR4 G protein-coupled receptor 4 -0.472619
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.472544
SGCE sarcoglycan, epsilon -0.472511
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -0.472467
KLF9 Kruppel-like factor 9 -0.472357
ZNF32 zinc finger protein 32 -0.470784
DPYSL2 dihydropyrimidinase-like 2 -0.470684
JOSD1 Josephin domain containing 1 -0.469633
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.469208
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -0.467089
LTBP4 latent transforming growth factor beta binding protein 4 -0.465326
CSNK1D casein kinase 1, delta -0.46516
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.464114
KLHL18 kelch-like family member 18 -0.46347
DNPEP aspartyl aminopeptidase -0.461722
HOXA4 homeobox A4 -0.457625
CD34 CD34 molecule -0.457385
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.455345
LAMA4 laminin, alpha 4 -0.453316
CHRD chordin -0.452886
LMO7 LIM domain 7 -0.451625
FGF2 fibroblast growth factor 2 (basic) -0.450892
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -0.449478
MAPK12 mitogen-activated protein kinase 12 -0.448231
KLHDC10 kelch domain containing 10 -0.447247
GPM6A glycoprotein M6A -0.446534
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.444512
SIK2 salt-inducible kinase 2 -0.443156
LAMB2 laminin, beta 2 (laminin S) -0.442828
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.442641
ABLIM3 actin binding LIM protein family, member 3 -0.442571
EIF4A3 eukaryotic translation initiation factor 4A3 -0.441634
TTC28 tetratricopeptide repeat domain 28 -0.441287
KIAA0391 KIAA0391 -0.441259
PBX1 pre-B-cell leukemia homeobox 1 -0.440481
HYAL2 hyaluronoglucosaminidase 2 -0.440325
FAM107A family with sequence similarity 107, member A -0.439601
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.437479
CDC37 cell division cycle 37 -0.437411
KLC1 kinesin light chain 1 -0.436805
FGFR4 fibroblast growth factor receptor 4 -0.435488
GDF10 growth differentiation factor 10 -0.434534
CALCA calcitonin-related polypeptide alpha -0.434131
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.431697
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.431337
PPP1R12B protein phosphatase 1, regulatory subunit 12B -0.429784
NCOA1 nuclear receptor coactivator 1 -0.428749
LBX1 ladybird homeobox 1 -0.426935
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.425741
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.424455
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.422262
SNX1 sorting nexin 1 -0.421587
HEG1 heart development protein with EGF-like domains 1 -0.42145
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -0.421011
HLX H2.0-like homeobox -0.418961
FBXO7 F-box protein 7 -0.418867
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.418545
TGFB1 transforming growth factor, beta 1 -0.4185
ABLIM1 actin binding LIM protein 1 -0.41786
KIAA0232 KIAA0232 -0.417204
CRIP2 cysteine-rich protein 2 -0.416726
H3F3B H3 histone, family 3B (H3.3B) -0.415297
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -0.415168
FOXF1 forkhead box F1 -0.415124
MLH1 mutL homolog 1 -0.415027
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -0.415015
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 -0.413941
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -0.413336
HCFC1 host cell factor C1 -0.413327
ICAM2 intercellular adhesion molecule 2 -0.411794
TSPAN9 tetraspanin 9 -0.411776
GPM6B glycoprotein M6B -0.411152
ARHGAP19 Rho GTPase activating protein 19 -0.411073
NFIB nuclear factor I/B -0.410621
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -0.410052
TUBA1A tubulin, alpha 1a -0.409542
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.407948
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.406802
TEX261 testis expressed 261 -0.40398
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -0.403587
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -0.402993
NUP188 nucleoporin 188kDa -0.402338
KAZN kazrin, periplakin interacting protein -0.402179
DENND5A DENN/MADD domain containing 5A -0.401327
CDH13 cadherin 13 -0.401118
RAB11A RAB11A, member RAS oncogene family -0.400643
SMG6 SMG6 nonsense mediated mRNA decay factor -0.400343
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) -0.400327
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.400126
IFRD1 interferon-related developmental regulator 1 -0.400079
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -0.400013
ANXA3 annexin A3 -0.399973
AGTR1 angiotensin II receptor, type 1 -0.3994
TCEAL1 transcription elongation factor A (SII)-like 1 -0.399342
RABEPK Rab9 effector protein with kelch motifs -0.39742
STX11 syntaxin 11 -0.397228
TP53BP2 tumor protein p53 binding protein 2 -0.395264
TRDMT1 tRNA aspartic acid methyltransferase 1 -0.394968
ESR2 estrogen receptor 2 (ER beta) -0.394051
SKIL SKI-like proto-oncogene -0.394007
PPP1R37 protein phosphatase 1, regulatory subunit 37 -0.393889
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -0.393358
KDR kinase insert domain receptor -0.392256
ARID5A AT rich interactive domain 5A (MRF1-like) -0.391036
CA4 carbonic anhydrase IV -0.389867
TMEM41B transmembrane protein 41B -0.388496
WWTR1 WW domain containing transcription regulator 1 -0.38716
UBE2N ubiquitin-conjugating enzyme E2N -0.386879
FGFR1 fibroblast growth factor receptor 1 -0.38606
ATF4 activating transcription factor 4 -0.383772
CUX1 cut-like homeobox 1 -0.382272
RXRA retinoid X receptor, alpha -0.382115
SDC2 syndecan 2 -0.381012
R3HCC1 R3H domain and coiled-coil containing 1 -0.380693
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.380554
ZNF609 zinc finger protein 609 -0.380309
CRISP2 cysteine-rich secretory protein 2 -0.380203
TCTA T-cell leukemia translocation altered -0.379982
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.378744
LDB2 LIM domain binding 2 -0.378385
CAPN2 calpain 2, (m/II) large subunit -0.378204
STRN striatin, calmodulin binding protein -0.377827
MSX1 msh homeobox 1 -0.377048
KIAA0355 KIAA0355 -0.376595
CTNND1 catenin (cadherin-associated protein), delta 1 -0.376544
JUND jun D proto-oncogene -0.37634
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.376082
HEXIM1 hexamethylene bis-acetamide inducible 1 -0.375879
RRAS related RAS viral (r-ras) oncogene homolog -0.375481
WASF3 WAS protein family, member 3 -0.375473
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.375382
CSRP1 cysteine and glycine-rich protein 1 -0.375376
DGKD diacylglycerol kinase, delta 130kDa -0.375069
WDR82 WD repeat domain 82 -0.374658
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -0.374509
IFNA21 interferon, alpha 21 -0.373573
QKI QKI, KH domain containing, RNA binding -0.373276
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -0.373154
CARD10 caspase recruitment domain family, member 10 -0.373138
MGAM maltase-glucoamylase -0.37306
SCN2A sodium channel, voltage gated, type II alpha subunit -0.372126
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.371912
OLFML2A olfactomedin-like 2A -0.371864
STOM stomatin -0.371687
SLC10A3 solute carrier family 10, member 3 -0.368057
BDNF brain-derived neurotrophic factor -0.367342
C14ORF132 chromosome 14 open reading frame 132 -0.366726
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.366298
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -0.365998
PLCE1 phospholipase C, epsilon 1 -0.364308
RANBP2 RAN binding protein 2 -0.364001
EVI5 ecotropic viral integration site 5 -0.363179
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.363041
DIAPH2 diaphanous-related formin 2 -0.362877
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.361905
ZHX3 zinc fingers and homeoboxes 3 -0.361544
FASN fatty acid synthase -0.361533
VCL vinculin -0.360448
PTPRB protein tyrosine phosphatase, receptor type, B -0.358425
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -0.357412
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -0.356861
DOCK9 dedicator of cytokinesis 9 -0.356349
LARP7 La ribonucleoprotein domain family, member 7 -0.355824
FDPS farnesyl diphosphate synthase -0.355127
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.354289
SH2B3 SH2B adaptor protein 3 -0.353456
SNX3 sorting nexin 3 -0.353321
ACD adrenocortical dysplasia homolog (mouse) -0.352936
SRF serum response factor (c-fos serum response element-binding transcription factor) -0.352345
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -0.352219
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -0.352123
DUSP8 dual specificity phosphatase 8 -0.351303
DLC1 DLC1 Rho GTPase activating protein -0.350761
CASC3 cancer susceptibility candidate 3 -0.349382
EPB42 erythrocyte membrane protein band 4.2 -0.348018
GJC2 gap junction protein, gamma 2, 47kDa -0.347901
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.347372
TEAD4 TEA domain family member 4 -0.347035
ZNF460 zinc finger protein 460 -0.346882
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.346642
TACC2 transforming, acidic coiled-coil containing protein 2 -0.3465
ADGRB3 adhesion G protein-coupled receptor B3 -0.344829
TEK TEK tyrosine kinase, endothelial -0.344752
PDGFB platelet-derived growth factor beta polypeptide -0.344251
ADAM7 ADAM metallopeptidase domain 7 -0.344014
MAPK11 mitogen-activated protein kinase 11 -0.343879
PRM2 protamine 2 -0.343244
DTX4 deltex 4, E3 ubiquitin ligase -0.343063
CPA1 carboxypeptidase A1 (pancreatic) -0.342929
MOB4 MOB family member 4, phocein -0.342875
PUF60 poly-U binding splicing factor 60KDa -0.342562
ADGRE5 adhesion G protein-coupled receptor E5 -0.341479
GTPBP10 GTP-binding protein 10 (putative) -0.34146
TCOF1 Treacher Collins-Franceschetti syndrome 1 -0.341038
LEPROT leptin receptor overlapping transcript -0.340957
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -0.340887
NR3C2 nuclear receptor subfamily 3, group C, member 2 -0.340854
TGFBR3 transforming growth factor, beta receptor III -0.340161
CRIP1 cysteine-rich protein 1 (intestinal) -0.340028