Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3524
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Genes

600 genes differentially expressed during Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 3.55041
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 3.10008
GMFB glia maturation factor, beta 3.04523
C19ORF66 chromosome 19 open reading frame 66 2.92258
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.87669
GCC2 GRIP and coiled-coil domain containing 2 2.8761
HLTF helicase-like transcription factor 2.85749
LITAF lipopolysaccharide-induced TNF factor 2.78471
ADAR adenosine deaminase, RNA-specific 2.76739
SASH3 SAM and SH3 domain containing 3 2.68935
RBBP7 retinoblastoma binding protein 7 2.63823
AIM2 absent in melanoma 2 2.58049
SNX6 sorting nexin 6 2.5117
TRIM45 tripartite motif containing 45 2.46274
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 2.4603
RBM12B RNA binding motif protein 12B 2.42294
SND1 staphylococcal nuclease and tudor domain containing 1 2.39947
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.37139
MORF4L1 mortality factor 4 like 1 2.3535
EFR3A EFR3 homolog A (S. cerevisiae) 2.3353
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.30963
PMS2P2 postmeiotic segregation increased 2 pseudogene 2 2.30072
ITPK1 inositol-tetrakisphosphate 1-kinase 2.28711
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2.28096
SV2C synaptic vesicle glycoprotein 2C 2.26768
MTF2 metal response element binding transcription factor 2 2.26083
RSRC1 arginine/serine-rich coiled-coil 1 2.25298
SLC30A5 solute carrier family 30 (zinc transporter), member 5 2.25293
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.22881
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.1979
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.18856
HDAC2 histone deacetylase 2 2.18366
NBN nibrin 2.17603
RNF111 ring finger protein 111 2.16367
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.14748
SNUPN snurportin 1 2.1386
MBD4 methyl-CpG binding domain protein 4 2.13073
RAD21 RAD21 homolog (S. pombe) 2.12967
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 2.12663
B2M beta-2-microglobulin 2.12033
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.11932
TRIM8 tripartite motif containing 8 2.09434
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 2.06942
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 2.05187
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.05125
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 2.04852
ATF5 activating transcription factor 5 2.04581
SUMO3 small ubiquitin-like modifier 3 2.04033
SLC39A8 solute carrier family 39 (zinc transporter), member 8 2.03654
HOXD11 homeobox D11 2.02348
FTL ferritin, light polypeptide 2.02332
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 2.0191
COMMD4 COMM domain containing 4 2.01236
RPN2 ribophorin II 2.01186
PARP12 poly (ADP-ribose) polymerase family, member 12 1.99757
KLF12 Kruppel-like factor 12 1.99215
SP110 SP110 nuclear body protein 1.98878
ADAM10 ADAM metallopeptidase domain 10 1.96697
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.95469
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 1.95463
MDK midkine (neurite growth-promoting factor 2) 1.95177
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.94977
M6PR mannose-6-phosphate receptor (cation dependent) 1.94441
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1.94291
HLA-C major histocompatibility complex, class I, C 1.93742
DPP3 dipeptidyl-peptidase 3 1.93534
BMPR1A bone morphogenetic protein receptor, type IA 1.9322
FOXP1 forkhead box P1 1.92395
ARMC1 armadillo repeat containing 1 1.91278
BET1 Bet1 golgi vesicular membrane trafficking protein 1.90725
LGI3 leucine-rich repeat LGI family, member 3 1.89598
TROAP trophinin associated protein 1.89402
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.8927
POT1 protection of telomeres 1 1.88767
SKAP2 src kinase associated phosphoprotein 2 1.88541
DZIP3 DAZ interacting zinc finger protein 3 1.88172
PRUNE prune exopolyphosphatase 1.88124
KIAA1033 KIAA1033 1.87791
BBX bobby sox homolog (Drosophila) 1.87631
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.87512
TSNAX translin-associated factor X 1.87422
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 1.86948
RNF130 ring finger protein 130 1.86703
IFT81 intraflagellar transport 81 1.86678
MAGT1 magnesium transporter 1 1.86515
PLSCR1 phospholipid scramblase 1 1.86457
APP amyloid beta (A4) precursor protein 1.86391
PDCL phosducin-like 1.86248
NECAB3 N-terminal EF-hand calcium binding protein 3 1.86204
HMG20A high mobility group 20A 1.86124
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.85809
GLG1 golgi glycoprotein 1 1.84645
PFDN1 prefoldin subunit 1 1.84178
PEX14 peroxisomal biogenesis factor 14 1.8349
C1ORF27 chromosome 1 open reading frame 27 1.83417
FAM3C family with sequence similarity 3, member C 1.83307
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.83304
GLIPR1 GLI pathogenesis-related 1 1.83068
KIF4A kinesin family member 4A 1.82985
HSF2BP heat shock transcription factor 2 binding protein 1.8272
COG2 component of oligomeric golgi complex 2 1.8272
IFI16 interferon, gamma-inducible protein 16 1.82431
ZFR zinc finger RNA binding protein 1.82365
FNDC3B fibronectin type III domain containing 3B 1.82343
CTNNBL1 catenin, beta like 1 1.81976
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.81595
SMAD1 SMAD family member 1 1.81426
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.8114
ZC3H7A zinc finger CCCH-type containing 7A 1.80805
HELZ helicase with zinc finger 1.80726
YIPF5 Yip1 domain family, member 5 1.80318
CSK c-src tyrosine kinase 1.79811
PHF21A PHD finger protein 21A 1.79721
TM2D3 TM2 domain containing 3 1.79138
MRPS34 mitochondrial ribosomal protein S34 1.78081
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 1.78013
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 1.77984
CHD8 chromodomain helicase DNA binding protein 8 1.77861
HDGFRP3 hepatoma-derived growth factor, related protein 3 1.77834
FANCE Fanconi anemia, complementation group E 1.77821
SLC25A38 solute carrier family 25, member 38 1.77743
SEPHS1 selenophosphate synthetase 1 1.76811
ZNF148 zinc finger protein 148 1.7626
SIPA1L3 signal-induced proliferation-associated 1 like 3 1.76092
TGDS TDP-glucose 4,6-dehydratase 1.75753
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.7564
TUG1 taurine up-regulated 1 (non-protein coding) 1.74509
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 1.74043
ATR ATR serine/threonine kinase 1.73537
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.73393
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.72708
NCBP2 nuclear cap binding protein subunit 2, 20kDa 1.72575
PARL presenilin associated, rhomboid-like 1.72008
USP18 ubiquitin specific peptidase 18 1.71967
TBCC tubulin folding cofactor C 1.71784
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.71624
FADS2 fatty acid desaturase 2 1.71265
MARVELD2 MARVEL domain containing 2 1.70333
SAP130 Sin3A-associated protein, 130kDa 1.70319
SKIL SKI-like proto-oncogene 1.70154
NSUN5 NOP2/Sun domain family, member 5 1.69525
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.69473
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.69237
KPNA1 karyopherin alpha 1 (importin alpha 5) 1.69065
DSG2 desmoglein 2 1.68965
LDHB lactate dehydrogenase B 1.68773
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 1.68691
C5ORF28 chromosome 5 open reading frame 28 1.68652
KIF2A kinesin heavy chain member 2A 1.68614
MRPL28 mitochondrial ribosomal protein L28 1.68441
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.68332
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 1.68302
MOCOS molybdenum cofactor sulfurase 1.67533
AK2 adenylate kinase 2 1.67399
RTP4 receptor (chemosensory) transporter protein 4 1.67261
PALB2 partner and localizer of BRCA2 1.66741
COG5 component of oligomeric golgi complex 5 1.66672
TTC30A tetratricopeptide repeat domain 30A 1.6605
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.65494
PRMT1 protein arginine methyltransferase 1 1.65278
ANAPC13 anaphase promoting complex subunit 13 1.63824
VEGFB vascular endothelial growth factor B 1.63767
DTX4 deltex 4, E3 ubiquitin ligase 1.63652
PARN poly(A)-specific ribonuclease 1.63191
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.63068
LECT1 leukocyte cell derived chemotaxin 1 1.62928
NGRN neugrin, neurite outgrowth associated 1.62688
TSPAN2 tetraspanin 2 1.62629
APOL2 apolipoprotein L, 2 1.62206
AGRN agrin 1.62041
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.61491
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.61443
XAF1 XIAP associated factor 1 1.61442
GNPDA1 glucosamine-6-phosphate deaminase 1 1.61168
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.6095
DPP8 dipeptidyl-peptidase 8 1.60626
C1S complement component 1, s subcomponent 1.60412
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.60168
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.60134
UBR5 ubiquitin protein ligase E3 component n-recognin 5 1.5988
TMPO thymopoietin 1.59448
SHCBP1 SHC SH2-domain binding protein 1 1.59313
ACLY ATP citrate lyase 1.5911
DUSP12 dual specificity phosphatase 12 1.58347
NFE2L3 nuclear factor, erythroid 2-like 3 1.58223
RAB20 RAB20, member RAS oncogene family 1.57825
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 1.57619
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.57588
C7ORF49 chromosome 7 open reading frame 49 1.57072
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 1.56888
ZC3H4 zinc finger CCCH-type containing 4 1.56833
XYLT2 xylosyltransferase II 1.56829
TBK1 TANK-binding kinase 1 1.56175
MSRB1 methionine sulfoxide reductase B1 1.56106
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.56062
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.55922
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.55733
TOR3A torsin family 3, member A 1.55381
LAPTM4B lysosomal protein transmembrane 4 beta 1.54869
METTL5 methyltransferase like 5 1.5471
PNMA1 paraneoplastic Ma antigen 1 1.54588
TRIM21 tripartite motif containing 21 1.5438
PUF60 poly-U binding splicing factor 60KDa 1.54194
SCPEP1 serine carboxypeptidase 1 1.54147
UFL1 UFM1-specific ligase 1 1.53934
ARMT1 acidic residue methyltransferase 1 1.53913
CTSC cathepsin C 1.5387
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.53446
ORC6 origin recognition complex, subunit 6 1.53433
IGSF1 immunoglobulin superfamily, member 1 1.53287
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.53236
LHFPL2 lipoma HMGIC fusion partner-like 2 1.52969
IFI44 interferon-induced protein 44 1.52716
NTAN1 N-terminal asparagine amidase 1.52589
IFI44L interferon-induced protein 44-like 1.52385
STAT1 signal transducer and activator of transcription 1, 91kDa 1.52288
TFRC transferrin receptor 1.52196
RHEB Ras homolog enriched in brain 1.52191
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.51977
STX16 syntaxin 16 1.5157
DMXL2 Dmx-like 2 1.51443
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 1.51433
TMSB10 thymosin beta 10 1.51021
PPT1 palmitoyl-protein thioesterase 1 1.50828
PIAS3 protein inhibitor of activated STAT, 3 1.50744
SFXN1 sideroflexin 1 1.50587
RCN2 reticulocalbin 2, EF-hand calcium binding domain 1.50484
MAN2B2 mannosidase, alpha, class 2B, member 2 1.50483
MYO7A myosin VIIA 1.50132
DNAAF2 dynein, axonemal, assembly factor 2 1.49864
ERGIC2 ERGIC and golgi 2 1.49694
USB1 U6 snRNA biogenesis 1 1.49656
LRRC14 leucine rich repeat containing 14 1.49289
GCA grancalcin, EF-hand calcium binding protein 1.4894
ZDHHC17 zinc finger, DHHC-type containing 17 1.48435
SEC11A SEC11 homolog A (S. cerevisiae) 1.48234
CTSH cathepsin H 1.48123
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.4747
RNF115 ring finger protein 115 1.47236
MTIF2 mitochondrial translational initiation factor 2 1.47235
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 1.47212
DAP3 death associated protein 3 1.46967
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.46922
ADPGK ADP-dependent glucokinase 1.46883
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.46795
MCTP2 multiple C2 domains, transmembrane 2 1.46633
SEP15 15 kDa selenoprotein 1.463
LRRC40 leucine rich repeat containing 40 1.46187
TPST2 tyrosylprotein sulfotransferase 2 1.45818
SERP1 stress-associated endoplasmic reticulum protein 1 1.45575
U2SURP U2 snRNP-associated SURP domain containing 1.45478
NXPH4 neurexophilin 4 1.45074
STK3 serine/threonine kinase 3 1.45039
MED22 mediator complex subunit 22 1.45016
C9ORF91 chromosome 9 open reading frame 91 1.44852
FAM111A family with sequence similarity 111, member A 1.44732
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.44606
APOO apolipoprotein O 1.43775
ABHD10 abhydrolase domain containing 10 1.43448
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 1.43327
BTN3A1 butyrophilin, subfamily 3, member A1 1.43282
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.43224
SCRN1 secernin 1 1.43138
SLC38A6 solute carrier family 38, member 6 1.42907
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.42654
FAM178A family with sequence similarity 178, member A 1.42492
C2CD3 C2 calcium-dependent domain containing 3 1.42258
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.41879
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 1.41717
ZNF384 zinc finger protein 384 1.41641
TRIB2 tribbles pseudokinase 2 1.41358
OAZ1 ornithine decarboxylase antizyme 1 1.40861
HACD3 3-hydroxyacyl-CoA dehydratase 3 1.40776
TJAP1 tight junction associated protein 1 (peripheral) 1.40737
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.4065
CKAP5 cytoskeleton associated protein 5 1.4064
OXTR oxytocin receptor 1.40581
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 1.40349
MEF2A myocyte enhancer factor 2A 1.40159
C19ORF54 chromosome 19 open reading frame 54 1.39259
COX17 COX17 cytochrome c oxidase copper chaperone 1.39114
YEATS2 YEATS domain containing 2 1.39082
ABHD2 abhydrolase domain containing 2 1.38946
RNF114 ring finger protein 114 1.38797
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.38765
UXS1 UDP-glucuronate decarboxylase 1 1.38628
TCF4 transcription factor 4 1.38615
NSUN3 NOP2/Sun domain family, member 3 1.38468
HDAC1 histone deacetylase 1 1.38272
ADAM8 ADAM metallopeptidase domain 8 1.37963
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.37796
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.3771
RRAS related RAS viral (r-ras) oncogene homolog 1.377
STAG2 stromal antigen 2 1.37661
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 1.37539
FSCN1 fascin actin-bundling protein 1 1.37499
USP33 ubiquitin specific peptidase 33 1.37427
CBX3 chromobox homolog 3 1.37007
DAD1 defender against cell death 1 1.36914
TXNRD2 thioredoxin reductase 2 1.3688

decreased expression

Symbol Name Standardized Value
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -3.54158
NUP214 nucleoporin 214kDa -2.87969
RBM5 RNA binding motif protein 5 -2.87795
WASF2 WAS protein family, member 2 -2.86362
C17ORF70 chromosome 17 open reading frame 70 -2.82821
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -2.80008
STRN striatin, calmodulin binding protein -2.78264
MVK mevalonate kinase -2.77983
HCFC1 host cell factor C1 -2.77071
ACADVL acyl-CoA dehydrogenase, very long chain -2.76114
RANBP9 RAN binding protein 9 -2.687
HDAC6 histone deacetylase 6 -2.67796
TRAPPC9 trafficking protein particle complex 9 -2.66387
SCAP SREBF chaperone -2.6514
ELL3 elongation factor RNA polymerase II-like 3 -2.60875
MAK16 MAK16 homolog (S. cerevisiae) -2.59654
OXSR1 oxidative stress responsive 1 -2.59421
HSBP1 heat shock factor binding protein 1 -2.58229
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.57684
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.52901
TMEM43 transmembrane protein 43 -2.47685
C7ORF26 chromosome 7 open reading frame 26 -2.45173
WDR82 WD repeat domain 82 -2.445
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.43981
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -2.41941
HARS histidyl-tRNA synthetase -2.41829
QARS glutaminyl-tRNA synthetase -2.40668
TMED3 transmembrane emp24 protein transport domain containing 3 -2.37733
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.36953
MYD88 myeloid differentiation primary response 88 -2.36712
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -2.36322
PITPNA phosphatidylinositol transfer protein, alpha -2.35657
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.35643
CBR4 carbonyl reductase 4 -2.35399
MINK1 misshapen-like kinase 1 -2.34539
PNPLA6 patatin-like phospholipase domain containing 6 -2.33398
PAPPA2 pappalysin 2 -2.3267
CAMTA2 calmodulin binding transcription activator 2 -2.31478
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.29869
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -2.2869
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.27434
NXF1 nuclear RNA export factor 1 -2.2619
GOLGA4 golgin A4 -2.25835
ADNP2 ADNP homeobox 2 -2.25223
DYNLL1 dynein, light chain, LC8-type 1 -2.25001
TEX2 testis expressed 2 -2.23134
CPA2 carboxypeptidase A2 (pancreatic) -2.22487
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.22246
MADD MAP-kinase activating death domain -2.21917
LMBR1L limb development membrane protein 1-like -2.21587
NAGK N-acetylglucosamine kinase -2.2146
C15ORF39 chromosome 15 open reading frame 39 -2.21316
RNF126 ring finger protein 126 -2.19424
SNRK SNF related kinase -2.19201
MYO1A myosin IA -2.19187
ACTG1 actin gamma 1 -2.19009
HOXB5 homeobox B5 -2.16884
PNP purine nucleoside phosphorylase -2.16793
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.15718
G6PC2 glucose-6-phosphatase, catalytic, 2 -2.15319
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -2.14507
SH3GL3 SH3-domain GRB2-like 3 -2.14119
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 -2.13929
IL13RA1 interleukin 13 receptor, alpha 1 -2.13214
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -2.12994
MBD1 methyl-CpG binding domain protein 1 -2.12646
ACAA1 acetyl-CoA acyltransferase 1 -2.12365
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.11503
PRDM2 PR domain containing 2, with ZNF domain -2.101
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -2.09961
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -2.094
DESI1 desumoylating isopeptidase 1 -2.09335
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -2.09153
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -2.08705
MGST2 microsomal glutathione S-transferase 2 -2.08652
PGC progastricsin (pepsinogen C) -2.07599
DCT dopachrome tautomerase -2.07088
GAPVD1 GTPase activating protein and VPS9 domains 1 -2.07086
TYRP1 tyrosinase-related protein 1 -2.06103
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 -2.05793
WDTC1 WD and tetratricopeptide repeats 1 -2.05624
CDK2 cyclin-dependent kinase 2 -2.04668
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -2.04136
CCDC9 coiled-coil domain containing 9 -2.03742
PEG3 paternally expressed 3 -2.02887
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -2.02079
MED8 mediator complex subunit 8 -2.01957
GFOD2 glucose-fructose oxidoreductase domain containing 2 -1.99903
TATDN2 TatD DNase domain containing 2 -1.98943
COPS6 COP9 signalosome subunit 6 -1.98196
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.97407
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -1.97359
AAMP angio-associated, migratory cell protein -1.96391
TRAK1 trafficking protein, kinesin binding 1 -1.95419
NBPF14 neuroblastoma breakpoint family, member 14 -1.94602
TBC1D13 TBC1 domain family, member 13 -1.94371
RUFY3 RUN and FYVE domain containing 3 -1.94204
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -1.92976
PAX8 paired box 8 -1.92533
KIAA0232 KIAA0232 -1.9232
TEX261 testis expressed 261 -1.92299
TXN thioredoxin -1.92019
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -1.91866
SRPK1 SRSF protein kinase 1 -1.91848
BCL2L2 BCL2-like 2 -1.91423
SUN1 Sad1 and UNC84 domain containing 1 -1.90888
MBD5 methyl-CpG binding domain protein 5 -1.90698
MTMR9 myotubularin related protein 9 -1.90384
PRDM9 PR domain containing 9 -1.89932
TOX4 TOX high mobility group box family member 4 -1.89242
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -1.89068
C18ORF25 chromosome 18 open reading frame 25 -1.88216
PCF11 PCF11 cleavage and polyadenylation factor subunit -1.87852
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.87714
TUBA1C tubulin, alpha 1c -1.8753
CD59 CD59 molecule, complement regulatory protein -1.87049
ELOVL1 ELOVL fatty acid elongase 1 -1.85659
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.85433
EXOSC7 exosome component 7 -1.84899
PDLIM5 PDZ and LIM domain 5 -1.8488
NOP56 NOP56 ribonucleoprotein -1.84565
MOSPD2 motile sperm domain containing 2 -1.84366
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 -1.83444
ZBTB5 zinc finger and BTB domain containing 5 -1.82999
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) -1.82362
LMNA lamin A/C -1.82158
EIF5B eukaryotic translation initiation factor 5B -1.82107
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -1.82008
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -1.81947
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -1.818
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -1.81738
MED16 mediator complex subunit 16 -1.8102
MYO15B myosin XVB -1.80734
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -1.8071
CFAP74 cilia and flagella associated protein 74 -1.8036
WIPI2 WD repeat domain, phosphoinositide interacting 2 -1.80117
RPS14 ribosomal protein S14 -1.79913
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -1.79207
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.79098
DUSP7 dual specificity phosphatase 7 -1.78924
ZNF710 zinc finger protein 710 -1.78737
EIF3M eukaryotic translation initiation factor 3, subunit M -1.78706
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.78525
UNC45A unc-45 homolog A (C. elegans) -1.78174
FRMD4B FERM domain containing 4B -1.77735
WIPF2 WAS/WASL interacting protein family, member 2 -1.77707
GON4L gon-4-like (C. elegans) -1.76971
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -1.76034
RIN1 Ras and Rab interactor 1 -1.76033
PTPRE protein tyrosine phosphatase, receptor type, E -1.75872
EPN2 epsin 2 -1.75687
SARS seryl-tRNA synthetase -1.7567
CXXC1 CXXC finger protein 1 -1.75319
SRP72 signal recognition particle 72kDa -1.74914
RPL23 ribosomal protein L23 -1.74568
MZF1 myeloid zinc finger 1 -1.74279
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -1.74153
DUOX1 dual oxidase 1 -1.73955
ZNF133 zinc finger protein 133 -1.73765
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.73735
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -1.73259
C12ORF29 chromosome 12 open reading frame 29 -1.72553
NOL6 nucleolar protein 6 (RNA-associated) -1.71868
JRK Jrk homolog (mouse) -1.71795
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.7137
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.71113
HECA headcase homolog (Drosophila) -1.7078
AIM1 absent in melanoma 1 -1.70722
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.70571
PRPF19 pre-mRNA processing factor 19 -1.70028
ALPPL2 alkaline phosphatase, placental-like 2 -1.6994
DSTN destrin (actin depolymerizing factor) -1.6989
C1ORF109 chromosome 1 open reading frame 109 -1.69858
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -1.69788
RPS18 ribosomal protein S18 -1.69548
STX7 syntaxin 7 -1.69392
IMMT inner membrane protein, mitochondrial -1.69336
PPP1R3C protein phosphatase 1, regulatory subunit 3C -1.68826
RANBP2 RAN binding protein 2 -1.68772
ZDHHC18 zinc finger, DHHC-type containing 18 -1.6807
WDR43 WD repeat domain 43 -1.67408
RPL27 ribosomal protein L27 -1.67041
TPT1 tumor protein, translationally-controlled 1 -1.66894
SEH1L SEH1-like (S. cerevisiae) -1.66841
SORBS1 sorbin and SH3 domain containing 1 -1.6674
PLS3 plastin 3 -1.66319
SGPL1 sphingosine-1-phosphate lyase 1 -1.66251
NPR3 natriuretic peptide receptor 3 -1.66106
HYAL2 hyaluronoglucosaminidase 2 -1.65919
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.65901
RPL38 ribosomal protein L38 -1.65839
EIF1AX eukaryotic translation initiation factor 1A, X-linked -1.65831
TUSC2 tumor suppressor candidate 2 -1.6557
PEA15 phosphoprotein enriched in astrocytes 15 -1.6552
CCT2 chaperonin containing TCP1, subunit 2 (beta) -1.65396
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -1.65355
UNC13B unc-13 homolog B (C. elegans) -1.64361
LOC440434 aminopeptidase puromycin sensitive pseudogene -1.64086
TOR1AIP1 torsin A interacting protein 1 -1.63572
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -1.63458
TUBB4B tubulin, beta 4B class IVb -1.63375
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -1.62953
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -1.62621
MLPH melanophilin -1.62557
ALAS1 5'-aminolevulinate synthase 1 -1.62491
GPX3 glutathione peroxidase 3 -1.62132
NFRKB nuclear factor related to kappaB binding protein -1.62027
TRIM3 tripartite motif containing 3 -1.61653
STXBP6 syntaxin binding protein 6 (amisyn) -1.60569
DIAPH1 diaphanous-related formin 1 -1.60557
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -1.60518
RPS13 ribosomal protein S13 -1.60494
FAM53B family with sequence similarity 53, member B -1.60487
HYLS1 hydrolethalus syndrome 1 -1.60429
LPIN1 lipin 1 -1.59941
C20ORF27 chromosome 20 open reading frame 27 -1.599
ZNF419 zinc finger protein 419 -1.59859
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -1.59408
ATF4 activating transcription factor 4 -1.59282
BAG3 BCL2-associated athanogene 3 -1.59117
SIRT3 sirtuin 3 -1.58882
BYSL bystin-like -1.58595
RAP1A RAP1A, member of RAS oncogene family -1.58506
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.58482
ZFAND3 zinc finger, AN1-type domain 3 -1.5848
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.58073
UBXN1 UBX domain protein 1 -1.57853
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -1.57834
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -1.57753
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.57729
KCTD2 potassium channel tetramerization domain containing 2 -1.57599
ATG2B autophagy related 2B -1.57143
KAT6A K(lysine) acetyltransferase 6A -1.57018
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.56751
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -1.56713
CAMK2B calcium/calmodulin-dependent protein kinase II beta -1.56475
PRPF8 pre-mRNA processing factor 8 -1.5581
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -1.55709
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -1.55
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.54963
GRM6 glutamate receptor, metabotropic 6 -1.54962
KLF8 Kruppel-like factor 8 -1.54867
SH3PXD2A SH3 and PX domains 2A -1.54865
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -1.54753
FOXN3 forkhead box N3 -1.54385
RPP14 ribonuclease P/MRP 14kDa subunit -1.54182
GOLGA2 golgin A2 -1.53708
GOSR1 golgi SNAP receptor complex member 1 -1.53382
EXPH5 exophilin 5 -1.5336
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -1.53287
TMEM40 transmembrane protein 40 -1.53269
RPL37A ribosomal protein L37a -1.5325
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.53111
HDAC3 histone deacetylase 3 -1.52823
FARSA phenylalanyl-tRNA synthetase, alpha subunit -1.52663
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.52595
PQLC1 PQ loop repeat containing 1 -1.52546
MAD2L1BP MAD2L1 binding protein -1.52379
TSPO translocator protein (18kDa) -1.52245
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -1.5218
XPO6 exportin 6 -1.5212
NFYC nuclear transcription factor Y, gamma -1.52002
STX17 syntaxin 17 -1.5196
DCAF7 DDB1 and CUL4 associated factor 7 -1.5181
XPA xeroderma pigmentosum, complementation group A -1.51776
KLHL20 kelch-like family member 20 -1.51763
GLUD1 glutamate dehydrogenase 1 -1.51419
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.51368
SF3B5 splicing factor 3b, subunit 5, 10kDa -1.51053
TUBB3 tubulin, beta 3 class III -1.50979
IFNG interferon, gamma -1.50963
CLDN17 claudin 17 -1.50801
NCKIPSD NCK interacting protein with SH3 domain -1.50655
ANKRD10 ankyrin repeat domain 10 -1.50635
SH3GL1 SH3-domain GRB2-like 1 -1.50127
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.5004
LARP7 La ribonucleoprotein domain family, member 7 -1.49864
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -1.49833
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -1.49194
TMEM9B TMEM9 domain family, member B -1.48696
IFRD1 interferon-related developmental regulator 1 -1.48633
TPCN1 two pore segment channel 1 -1.48364
GPS2 G protein pathway suppressor 2 -1.48282
TRIM13 tripartite motif containing 13 -1.48127
THUMPD2 THUMP domain containing 2 -1.48116
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.48033
CEP250 centrosomal protein 250kDa -1.4769
TFB1M transcription factor B1, mitochondrial -1.47616
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.47538
ALS2CL ALS2 C-terminal like -1.47449
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -1.47226
AMOTL2 angiomotin like 2 -1.4711
FBXO3 F-box protein 3 -1.46928
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.46894
MOS v-mos Moloney murine sarcoma viral oncogene homolog -1.46796
NUFIP1P nuclear fragile X mental retardation protein interacting protein 1 pseudogene -1.46758
PDCD11 programmed cell death 11 -1.46703
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -1.46555
WNT6 wingless-type MMTV integration site family, member 6 -1.46444
SIGLEC6 sialic acid binding Ig-like lectin 6 -1.46397