Spinal Cord Injuries Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group neurological (Genetic Association Database)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D013119
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Genes

65 genes/proteins associated with the disease Spinal Cord Injuries from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AQP4 aquaporin 4 2.88009
SOD1 superoxide dismutase 1, soluble 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.88009
AKT1S1 AKT1 substrate 1 (proline-rich) 2.88009
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.88009
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.88009
VEGFA vascular endothelial growth factor A 2.88009
AQP1 aquaporin 1 (Colton blood group) 2.88009
MAPK1 mitogen-activated protein kinase 1 1.437
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.41721
MMP3 matrix metallopeptidase 3 1.37504
IL4 interleukin 4 1.37332
MAPK3 mitogen-activated protein kinase 3 1.34723
IL6 interleukin 6 1.33523
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.3314
FOS FBJ murine osteosarcoma viral oncogene homolog 1.29875
CCL2 chemokine (C-C motif) ligand 2 1.29194
CXCL8 chemokine (C-X-C motif) ligand 8 1.28703
EDN1 endothelin 1 1.27936
TNF tumor necrosis factor 1.26329
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.26329
VWF von Willebrand factor 1.25463
XBP1 X-box binding protein 1 1.25183
IL12A interleukin 12A 1.25028
GSK3B glycogen synthase kinase 3 beta 1.22501
NOS2 nitric oxide synthase 2, inducible 1.22469
JAK1 Janus kinase 1 1.21887
TIMP1 TIMP metallopeptidase inhibitor 1 1.21695
NOS1 nitric oxide synthase 1 (neuronal) 1.21304
SMAD2 SMAD family member 2 1.19933
ICAM1 intercellular adhesion molecule 1 1.19146
OCLN occludin 1.19113
BCL2 B-cell CLL/lymphoma 2 1.17662
APP amyloid beta (A4) precursor protein 1.17067
MMP9 matrix metallopeptidase 9 1.16633
SREBF1 sterol regulatory element binding transcription factor 1 1.16467
IL1B interleukin 1, beta 1.15627
TGFB1 transforming growth factor, beta 1 1.14919
CXCL10 chemokine (C-X-C motif) ligand 10 1.14166
MMP2 matrix metallopeptidase 2 1.12219
IL12B interleukin 12B 1.11673
FN1 fibronectin 1 1.11571
CCL5 chemokine (C-C motif) ligand 5 1.09611
LBP lipopolysaccharide binding protein 1.09262
SELL selectin L 1.08762
IFNG interferon, gamma 1.08478
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.08019
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.07376
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.06515
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.06225
THBD thrombomodulin 1.05864
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.05349
COL1A1 collagen, type I, alpha 1 1.04904
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.04684
RB1 retinoblastoma 1 1.04352
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.03715
THRSP thyroid hormone responsive 1.03493
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.03419
CD36 CD36 molecule (thrombospondin receptor) 1.02933
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.02485
TLR4 toll-like receptor 4 1.02373
STAT1 signal transducer and activator of transcription 1, 91kDa 1.02151
NPPA natriuretic peptide A 1.01928
IL2 interleukin 2 1.01625
TFRC transferrin receptor 1.01474