Sleep Disorders Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012893
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Genes

668 genes/proteins associated with the disease Sleep Disorders from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL1B interleukin 1, beta 2.88009
POMC proopiomelanocortin 2.88009
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 2.88009
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.88009
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.88009
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.51293
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.49113
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.40424
FOS FBJ murine osteosarcoma viral oncogene homolog 2.4035
PRL prolactin 2.38876
TNF tumor necrosis factor 2.38717
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.38441
BAX BCL2-associated X protein 2.38007
BCL2 B-cell CLL/lymphoma 2 2.36969
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.36491
DRD2 dopamine receptor D2 2.36388
CAT catalase 2.34921
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.32599
EGR1 early growth response 1 2.32393
MAPK1 mitogen-activated protein kinase 1 2.32106
BDNF brain-derived neurotrophic factor 2.3029
IL6 interleukin 6 2.29684
MAPK3 mitogen-activated protein kinase 3 2.28271
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.17469
TH tyrosine hydroxylase 2.16339
GSK3B glycogen synthase kinase 3 beta 2.14449
TP53 tumor protein p53 2.14275
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.14161
IL10 interleukin 10 2.11424
VEGFA vascular endothelial growth factor A 2.11353
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.10419
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.10319
GFAP glial fibrillary acidic protein 2.09522
NPY neuropeptide Y 2.09274
NOS2 nitric oxide synthase 2, inducible 2.09238
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.08609
BCL2L1 BCL2-like 1 2.08056
FAS Fas cell surface death receptor 2.07866
JUN jun proto-oncogene 2.07276
PENK proenkephalin 2.06909
ARC activity-regulated cytoskeleton-associated protein 2.06331
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.03833
DRD1 dopamine receptor D1 2.03432
SOD1 superoxide dismutase 1, soluble 2.03394
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.02971
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.02839
GSTP1 glutathione S-transferase pi 1 2.02641
NUPR1 nuclear protein, transcriptional regulator, 1 2.02585
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.02348
SOD2 superoxide dismutase 2, mitochondrial 2.01979
CREB1 cAMP responsive element binding protein 1 2.01787
CCL2 chemokine (C-C motif) ligand 2 2.00219
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.98843
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.98139
GNAS GNAS complex locus 1.98139
IL1A interleukin 1, alpha 1.97669
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.97288
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.96506
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.94829
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.94327
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.93414
GJA1 gap junction protein, alpha 1, 43kDa 1.92992
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.92343
PARP1 poly (ADP-ribose) polymerase 1 1.91814
TGFB1 transforming growth factor, beta 1 1.91765
IFNG interferon, gamma 1.88964
RGS4 regulator of G-protein signaling 4 1.8634
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.85834
MAPK14 mitogen-activated protein kinase 14 1.85712
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.85415
CRH corticotropin releasing hormone 1.85221
EDN1 endothelin 1 1.85169
CXCL8 chemokine (C-X-C motif) ligand 8 1.84888
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.84853
REN renin 1.84552
DUSP1 dual specificity phosphatase 1 1.8418
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.83841
HMOX1 heme oxygenase 1 1.83824
DDIT3 DNA-damage-inducible transcript 3 1.83521
GDNF glial cell derived neurotrophic factor 1.83254
COMT catechol-O-methyltransferase 1.83254
TAC1 tachykinin, precursor 1 1.83095
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.82307
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.82115
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.81738
JUNB jun B proto-oncogene 1.80623
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.80265
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.79579
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.79369
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.79159
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.79044
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.78778
FABP1 fatty acid binding protein 1, liver 1.78091
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.77686
COL1A1 collagen, type I, alpha 1 1.7716
INS insulin 1.77024
ADRB2 adrenoceptor beta 2, surface 1.76269
CCND1 cyclin D1 1.7621
C10ORF10 chromosome 10 open reading frame 10 1.75856
TAGLN transgelin 1.75699
EGFR epidermal growth factor receptor 1.75361
CTSL cathepsin L 1.75201
SGK1 serum/glucocorticoid regulated kinase 1 1.74621
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.74541
AVP arginine vasopressin 1.7446
INHBE inhibin, beta E 1.73938
CTSB cathepsin B 1.73475
MAPK8 mitogen-activated protein kinase 8 1.73292
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.73271
HOMER1 homer scaffolding protein 1 1.73028
GADD45A growth arrest and DNA-damage-inducible, alpha 1.72199
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.7185
MPO myeloperoxidase 1.71338
ADRB1 adrenoceptor beta 1 1.70553
SREBF1 sterol regulatory element binding transcription factor 1 1.70553
MMP9 matrix metallopeptidase 9 1.70347
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.69763
GPX1 glutathione peroxidase 1 1.69426
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.69254
MSMO1 methylsterol monooxygenase 1 1.68591
CYCS cytochrome c, somatic 1.68358
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.68316
APP amyloid beta (A4) precursor protein 1.6774
POR P450 (cytochrome) oxidoreductase 1.67654
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.67029
NGF nerve growth factor (beta polypeptide) 1.65908
F3 coagulation factor III (thromboplastin, tissue factor) 1.65775
IL2 interleukin 2 1.65577
HSPA8 heat shock 70kDa protein 8 1.65402
CDK2 cyclin-dependent kinase 2 1.64484
BAD BCL2-associated agonist of cell death 1.6428
PDYN prodynorphin 1.63541
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.63317
FGF2 fibroblast growth factor 2 (basic) 1.63183
FASLG Fas ligand (TNF superfamily, member 6) 1.63027
RGS2 regulator of G-protein signaling 2 1.62915
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.62335
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.61967
PRKCD protein kinase C, delta 1.61782
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.61506
IL4 interleukin 4 1.61037
GSTM1 glutathione S-transferase mu 1 1.60944
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.60874
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.60641
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.60594
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.6043
CREM cAMP responsive element modulator 1.6036
NOS1 nitric oxide synthase 1 (neuronal) 1.60314
CDK5 cyclin-dependent kinase 5 1.59381
LEP leptin 1.59334
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.59264
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.58889
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.57426
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.56435
IGF1 insulin-like growth factor 1 (somatomedin C) 1.56312
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.56019
FN1 fibronectin 1 1.55624
EGR2 early growth response 2 1.55624
G6PD glucose-6-phosphate dehydrogenase 1.55574
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.55378
APOE apolipoprotein E 1.55255
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.55231
FOSL2 FOS-like antigen 2 1.55108
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.55059
ATM ATM serine/threonine kinase 1.55035
NPPA natriuretic peptide A 1.5462
SIGMAR1 sigma non-opioid intracellular receptor 1 1.54184
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.53917
MMP3 matrix metallopeptidase 3 1.53892
RB1 retinoblastoma 1 1.5382
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.53699
CTSD cathepsin D 1.53699
CDC42 cell division cycle 42 1.53579
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.53579
NOS3 nitric oxide synthase 3 (endothelial cell) 1.53555
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.53456
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.53258
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.53234
PRKCE protein kinase C, epsilon 1.52987
JAK1 Janus kinase 1 1.52963
PRKCB protein kinase C, beta 1.52767
CD151 CD151 molecule (Raph blood group) 1.52237
BBC3 BCL2 binding component 3 1.52061
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.51759
F2 coagulation factor II (thrombin) 1.51683
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.51632
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.51607
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.51255
HSPA1A heat shock 70kDa protein 1A 1.51255
LPL lipoprotein lipase 1.51255
HSPB1 heat shock 27kDa protein 1 1.51105
NFE2L2 nuclear factor, erythroid 2-like 2 1.50979
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.50953
CXCL10 chemokine (C-X-C motif) ligand 10 1.50524
GH1 growth hormone 1 1.50498
SPP1 secreted phosphoprotein 1 1.50373
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.50348
CFLAR CASP8 and FADD-like apoptosis regulator 1.50298
TRH thyrotropin-releasing hormone 1.49967
CCND3 cyclin D3 1.49635
LDLR low density lipoprotein receptor 1.49558
BIRC5 baculoviral IAP repeat containing 5 1.49508
DRD3 dopamine receptor D3 1.49508
PRKCA protein kinase C, alpha 1.49045
NAMPT nicotinamide phosphoribosyltransferase 1.48684
ALB albumin 1.48659
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.48145
PER1 period circadian clock 1 1.48145
PPARG peroxisome proliferator-activated receptor gamma 1.474
INHBA inhibin, beta A 1.47374
MMP13 matrix metallopeptidase 13 1.47141
ATF3 activating transcription factor 3 1.46883
XBP1 X-box binding protein 1 1.46727
SDC4 syndecan 4 1.46409
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.46225
GAL galanin/GMAP prepropeptide 1.46067
CHEK1 checkpoint kinase 1 1.45936
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.45405
CYP3A cytochrome P450, family 3, subfamily A 1.45405
MMP2 matrix metallopeptidase 2 1.45326
ADORA1 adenosine A1 receptor 1.45326
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.45115
GRIK2 glutamate receptor, ionotropic, kainate 2 1.44927
ICAM1 intercellular adhesion molecule 1 1.44899
ADRB3 adrenoceptor beta 3 1.44735
GRM1 glutamate receptor, metabotropic 1 1.44653
IGF1R insulin-like growth factor 1 receptor 1.44544
ACHE acetylcholinesterase (Yt blood group) 1.44436
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.44409
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.4313
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.42885
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.42885
GRM5 glutamate receptor, metabotropic 5 1.4202
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.4202
GAP43 growth associated protein 43 1.41911
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.41505
LHB luteinizing hormone beta polypeptide 1.41285
GEM GTP binding protein overexpressed in skeletal muscle 1.41202
HINT1 histidine triad nucleotide binding protein 1 1.41063
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.40842
APOB apolipoprotein B 1.40815
CCNE1 cyclin E1 1.40705
NPPB natriuretic peptide B 1.40595
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.40457
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.40429
UNG uracil-DNA glycosylase 1.40429
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.40148
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.39869
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.39591
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.3931
HDAC1 histone deacetylase 1 1.39282
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.39254
CALCA calcitonin-related polypeptide alpha 1.39254
ADORA2A adenosine A2a receptor 1.39002
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.38724
TXNRD1 thioredoxin reductase 1 1.38555
FSHB follicle stimulating hormone, beta polypeptide 1.38412
HSPA1B heat shock 70kDa protein 1B 1.38213
OPRM1 opioid receptor, mu 1 1.38213
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.37789
MAOA monoamine oxidase A 1.37789
CTGF connective tissue growth factor 1.37561
CNR1 cannabinoid receptor 1 (brain) 1.3716
VCAM1 vascular cell adhesion molecule 1 1.3716
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.37075
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.36961
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.3682
H2AFX H2A histone family, member X 1.36735
APOA1 apolipoprotein A-I 1.36735
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.36591
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.36562
MBP myelin basic protein 1.36275
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.36275
E2F1 E2F transcription factor 1 1.36133
MEF2A myocyte enhancer factor 2A 1.36047
EFNB3 ephrin-B3 1.35849
CASP12 caspase 12 (gene/pseudogene) 1.35502
ATF4 activating transcription factor 4 1.35328
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.35155
GSR glutathione reductase 1.35098
BMP4 bone morphogenetic protein 4 1.35012
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.34955
PCNA proliferating cell nuclear antigen 1.34811
MCL1 myeloid cell leukemia 1 1.34811
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.34752
SCARB1 scavenger receptor class B, member 1 1.34547
EFNA1 ephrin-A1 1.34518
ELK1 ELK1, member of ETS oncogene family 1.34518
FBXO32 F-box protein 32 1.34169
LOX lysyl oxidase 1.33995
NTS neurotensin 1.3385
ODC1 ornithine decarboxylase 1 1.33583
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.33583
STAR steroidogenic acute regulatory protein 1.33434
CES2 carboxylesterase 2 1.33257
JUND jun D proto-oncogene 1.33257
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.33022
TUBA1A tubulin, alpha 1a 1.32846
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.32786
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.32518
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.32518
CDK4 cyclin-dependent kinase 4 1.32518
CXCL2 chemokine (C-X-C motif) ligand 2 1.32488
FASN fatty acid synthase 1.32369
TIMP1 TIMP metallopeptidase inhibitor 1 1.32132
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.31897
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.31837
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.31566
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.31297
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.31267
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.31119
GSTO1 glutathione S-transferase omega 1 1.30941
KLF10 Kruppel-like factor 10 1.30941
PER2 period circadian clock 2 1.30941
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.30696
THBS1 thrombospondin 1 1.30666
BID BH3 interacting domain death agonist 1.30451
TOB1 transducer of ERBB2, 1 1.3039
BAG3 BCL2-associated athanogene 3 1.30329
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.30329
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.30329
MAPK9 mitogen-activated protein kinase 9 1.30147
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.30087
DUSP6 dual specificity phosphatase 6 1.2975
PPARA peroxisome proliferator-activated receptor alpha 1.29719
ITGB5 integrin, beta 5 1.29533
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.29533
ACO2 aconitase 2, mitochondrial 1.2941
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.2941
VLDLR very low density lipoprotein receptor 1.28827
CYR61 cysteine-rich, angiogenic inducer, 61 1.2861
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.28579
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.28395
IGF2 insulin-like growth factor 2 1.28395
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.28303
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.28303
CCNB1 cyclin B1 1.28272
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.27875
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.27875
MAP2K1 mitogen-activated protein kinase kinase 1 1.27813
FADS2 fatty acid desaturase 2 1.27657
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.27533
CGA glycoprotein hormones, alpha polypeptide 1.27502
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.27471
PDE4B phosphodiesterase 4B, cAMP-specific 1.27378
INSIG1 insulin induced gene 1 1.27316
EDNRB endothelin receptor type B 1.27316
GPX3 glutathione peroxidase 3 1.27316
S1PR1 sphingosine-1-phosphate receptor 1 1.27101
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.27101
HMGB2 high mobility group box 2 1.27101
BAK1 BCL2-antagonist/killer 1 1.26917
APOA4 apolipoprotein A-IV 1.26825
ATF2 activating transcription factor 2 1.26545
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.26329
PON1 paraoxonase 1 1.26329
ATF5 activating transcription factor 5 1.25929
TLR4 toll-like receptor 4 1.25838
NRP1 neuropilin 1 1.25745
CHGA chromogranin A 1.25745
VIM vimentin 1.25214
GCLC glutamate-cysteine ligase, catalytic subunit 1.25121
CCL5 chemokine (C-C motif) ligand 5 1.24966
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.24687
MAPT microtubule-associated protein tau 1.24465
TEX261 testis expressed 261 1.24433
FGFR1 fibroblast growth factor receptor 1 1.2415
GCH1 GTP cyclohydrolase 1 1.2415
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.24118
ACTB actin, beta 1.24087
ARRB1 arrestin, beta 1 1.24087
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.23899
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.23648
ADCY7 adenylate cyclase 7 1.23552
TF transferrin 1.23488
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.23424
CD44 CD44 molecule (Indian blood group) 1.23296
DDIT4 DNA-damage-inducible transcript 4 1.23106
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.23011
TIMP2 TIMP metallopeptidase inhibitor 2 1.22916
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.22727
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.22404
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.22404
SST somatostatin 1.22371
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.22339
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.22016
E2F3 E2F transcription factor 3 1.21984
AKR1C1 aldo-keto reductase family 1, member C1 1.21791
STIP1 stress-induced phosphoprotein 1 1.21337
ANXA4 annexin A4 1.21337
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.21239
TRHR thyrotropin-releasing hormone receptor 1.21043
MAP2 microtubule-associated protein 2 1.21011
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.21011
ASS1 argininosuccinate synthase 1 1.21011
IFI30 interferon, gamma-inducible protein 30 1.20978
NGFR nerve growth factor receptor 1.20687
EMP1 epithelial membrane protein 1 1.20687
STAT5B signal transducer and activator of transcription 5B 1.20526
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.20493
CALR calreticulin 1.2046
PLCD4 phospholipase C, delta 4 1.20196
ADRA2A adrenoceptor alpha 2A 1.19704
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.19412
EZR ezrin 1.1908
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.1908
GSTA2 glutathione S-transferase alpha 2 1.1908
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.18783
ACIN1 apoptotic chromatin condensation inducer 1 1.18652
PXMP4 peroxisomal membrane protein 4, 24kDa 1.18652
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.18652
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.18521
CYBB cytochrome b-245, beta polypeptide 1.18391
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.18193
TGFA transforming growth factor, alpha 1.18159
BMP2K BMP2 inducible kinase 1.17926
GSTM2 glutathione S-transferase mu 2 (muscle) 1.1786
RYR2 ryanodine receptor 2 (cardiac) 1.17761
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.17695
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.17563
MAP2K6 mitogen-activated protein kinase kinase 6 1.17563
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.17563
GSTT1 glutathione S-transferase theta 1 1.17497
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.173
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.17268
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.17268
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 1.17235
RRM2 ribonucleotide reductase M2 1.16866
MKI67 marker of proliferation Ki-67 1.16666
KRT8 keratin 8, type II 1.16633
MED13L mediator complex subunit 13-like 1.16533
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.16533
FNDC4 fibronectin type III domain containing 4 1.16533
DHCR24 24-dehydrocholesterol reductase 1.16104
NINJ1 ninjurin 1 1.16035
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.15627
ADORA2B adenosine A2b receptor 1.15627
CALB1 calbindin 1, 28kDa 1.15627
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.15526
CDC25B cell division cycle 25B 1.15526
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.15526
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.15526
PLAT plasminogen activator, tissue 1.15357
TGFB2 transforming growth factor, beta 2 1.15357
BRCA1 breast cancer 1, early onset 1.15357
TOP2A topoisomerase (DNA) II alpha 170kDa 1.15357
IL18 interleukin 18 1.15357
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.15256
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.15223
SCG2 secretogranin II 1.15223
NCOA3 nuclear receptor coactivator 3 1.15223
ITM2B integral membrane protein 2B 1.15189
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.14989
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.14816
PLTP phospholipid transfer protein 1.14816
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.14816
NEFH neurofilament, heavy polypeptide 1.14678
STAT1 signal transducer and activator of transcription 1, 91kDa 1.14575
CLOCK clock circadian regulator 1.14541
RGS9 regulator of G-protein signaling 9 1.14541
PSAP prosaposin 1.14404
BECN1 beclin 1, autophagy related 1.14404
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.14404
ATR ATR serine/threonine kinase 1.14404
KLF4 Kruppel-like factor 4 (gut) 1.14404
CLU clusterin 1.14234
XDH xanthine dehydrogenase 1.14234
TAAR1 trace amine associated receptor 1 1.142
TSC22D3 TSC22 domain family, member 3 1.14132
FOXO1 forkhead box O1 1.14132
NQO1 NAD(P)H dehydrogenase, quinone 1 1.14064
NPAS2 neuronal PAS domain protein 2 1.13929
ALDOA aldolase A, fructose-bisphosphate 1.13862
TFRC transferrin receptor 1.13621
CCND2 cyclin D2 1.13552
IL12A interleukin 12A 1.13347
ERBB2 erb-b2 receptor tyrosine kinase 2 1.13347
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.13347
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.13347
COL11A1 collagen, type XI, alpha 1 1.13245
RELN reelin 1.13245
IGFBP1 insulin-like growth factor binding protein 1 1.1294
PARK7 parkinson protein 7 1.12872
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.12805
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.12703
WISP1 WNT1 inducible signaling pathway protein 1 1.12703
TJP3 tight junction protein 3 1.12703
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.1253
SREBF2 sterol regulatory element binding transcription factor 2 1.12495
HSPE1 heat shock 10kDa protein 1 1.12288
EEF2 eukaryotic translation elongation factor 2 1.12288
CPT1A carnitine palmitoyltransferase 1A (liver) 1.12185
PF4 platelet factor 4 1.12117
ADCY6 adenylate cyclase 6 1.12117
INSR insulin receptor 1.12048
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.11911
TSC22D1 TSC22 domain family, member 1 1.11775
RHOB ras homolog family member B 1.11775
IDI1 isopentenyl-diphosphate delta isomerase 1 1.11775
PRLR prolactin receptor 1.11536
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.11536
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.11536
EGR3 early growth response 3 1.11046
WNT5A wingless-type MMTV integration site family, member 5A 1.11046
LPIN1 lipin 1 1.11046
PDIA3 protein disulfide isomerase family A, member 3 1.11011
FBXL3 F-box and leucine-rich repeat protein 3 1.10872
GSTA1 glutathione S-transferase alpha 1 1.10769
OAT ornithine aminotransferase 1.10769
WNT4 wingless-type MMTV integration site family, member 4 1.10665
VCL vinculin 1.10665
ALAD aminolevulinate dehydratase 1.10527
OPRD1 opioid receptor, delta 1 1.10353
SYP synaptophysin 1.10317
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.10282
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.10104
SQLE squalene epoxidase 1.10033
CAPN1 calpain 1, (mu/I) large subunit 1.09998
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.09963
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.09892
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.09857
STAT5A signal transducer and activator of transcription 5A 1.09646
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.09611
IGFBP5 insulin-like growth factor binding protein 5 1.09541
TJP1 tight junction protein 1 1.09541
ACTA2 actin, alpha 2, smooth muscle, aorta 1.09471
S100A9 S100 calcium binding protein A9 1.09332
SFPQ splicing factor proline/glutamine-rich 1.09297
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.09047
URI1 URI1, prefoldin-like chaperone 1.0894
EIF5 eukaryotic translation initiation factor 5 1.0894
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.0894
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.08797
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.08797
GSTA4 glutathione S-transferase alpha 4 1.08655
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.08619
RGCC regulator of cell cycle 1.08301
VWF von Willebrand factor 1.08301
EIF4B eukaryotic translation initiation factor 4B 1.08301
NFE2L1 nuclear factor, erythroid 2-like 1 1.08301
HPCAL1 hippocalcin-like 1 1.08301
UBC ubiquitin C 1.08301
CNOT7 CCR4-NOT transcription complex, subunit 7 1.08019
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.07947
TUBB3 tubulin, beta 3 class III 1.07947
PDGFB platelet-derived growth factor beta polypeptide 1.07911
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.07804
CARTPT CART prepropeptide 1.07804
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.07804
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.0766
CD4 CD4 molecule 1.07305
SDS serine dehydratase 1.07305
CA12 carbonic anhydrase XII 1.07305
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.07305
ASL argininosuccinate lyase 1.07305
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.07199
RND2 Rho family GTPase 2 1.07093
RAD51 RAD51 recombinase 1.06987
MAOB monoamine oxidase B 1.06987
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.06987
PKM pyruvate kinase, muscle 1.06987
STMN1 stathmin 1 1.06987
RAD50 RAD50 homolog (S. cerevisiae) 1.06987
PRKCG protein kinase C, gamma 1.06844
IL12B interleukin 12B 1.06698
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.06661
APAF1 apoptotic peptidase activating factor 1 1.06552
EPO erythropoietin 1.06552
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.06552
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.0637
CAPN2 calpain 2, (m/II) large subunit 1.0637
EIF4E eukaryotic translation initiation factor 4E 1.0637
SYT5 synaptotagmin V 1.06333
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 1.06333
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.06333
GSK3A glycogen synthase kinase 3 alpha 1.06333
PTK2 protein tyrosine kinase 2 1.06333
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.06297
ACAA1 acetyl-CoA acyltransferase 1 1.06297
CD68 CD68 molecule 1.06044
GJB2 gap junction protein, beta 2, 26kDa 1.06044
HPN hepsin 1.05864
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.05864
CDC25A cell division cycle 25A 1.05757
ANXA5 annexin A5 1.05648
PTK2B protein tyrosine kinase 2 beta 1.05461
PNMT phenylethanolamine N-methyltransferase 1.05423
CRP C-reactive protein, pentraxin-related 1.05423
PKN2 protein kinase N2 1.05386
INHA inhibin, alpha 1.05386
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.05349
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.05126
MAP2K2 mitogen-activated protein kinase kinase 2 1.04978
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.04941
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.04904
COX5B cytochrome c oxidase subunit Vb 1.04904
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.04904
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.04794
MANBA mannosidase, beta A, lysosomal 1.04611
SIPA1L1 signal-induced proliferation-associated 1 like 1 1.04574
IER3 immediate early response 3 1.04574
MMP1 matrix metallopeptidase 1 1.04574
PHGDH phosphoglycerate dehydrogenase 1.04538
RGS3 regulator of G-protein signaling 3 1.04465
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.04427
ANGPTL4 angiopoietin-like 4 1.04352
IRS1 insulin receptor substrate 1 1.04352
MARCKS myristoylated alanine-rich protein kinase C substrate 1.04239
ERN1 endoplasmic reticulum to nucleus signaling 1 1.04239
ECH1 enoyl CoA hydratase 1, peroxisomal 1.04239
TXNIP thioredoxin interacting protein 1.04126
CD36 CD36 molecule (thrombospondin receptor) 1.04088
PXN paxillin 1.04014
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.03939
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.03939
HPCA hippocalcin 1.03901
CDK1 cyclin-dependent kinase 1 1.03901
GDF15 growth differentiation factor 15 1.03752
PTEN phosphatase and tensin homolog 1.03752
MGST1 microsomal glutathione S-transferase 1 1.03715
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.03715
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.03641
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.03567
IRF9 interferon regulatory factor 9 1.03567
PVALB parvalbumin 1.03567
PHYH phytanoyl-CoA 2-hydroxylase 1.03567
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.0353
SPON2 spondin 2, extracellular matrix protein 1.0353
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.0353
GFRA1 GDNF family receptor alpha 1 1.0353
FST follistatin 1.03345
COL3A1 collagen, type III, alpha 1 1.03308
TPD52 tumor protein D52 1.03122
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 1.03122
ACOX2 acyl-CoA oxidase 2, branched chain 1.03084
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.03084
IL1RN interleukin 1 receptor antagonist 1.03084
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.03046
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.02671
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.02671
CHKA choline kinase alpha 1.02671
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.02671
PHB prohibitin 1.02485
DCAF8 DDB1 and CUL4 associated factor 8 1.02336
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.02225
PPL periplakin 1.02225
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.02225
TUBA4A tubulin, alpha 4a 1.02225
TNC tenascin C 1.02188
HRAS Harvey rat sarcoma viral oncogene homolog 1.0204
GCK glucokinase (hexokinase 4) 1.01928
HSF1 heat shock transcription factor 1 1.01928
USP2 ubiquitin specific peptidase 2 1.01814
ADK adenosine kinase 1.01814
ACKR3 atypical chemokine receptor 3 1.01814
OPRK1 opioid receptor, kappa 1 1.01663
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.01663
CRYAB crystallin, alpha B 1.01663
PLK2 polo-like kinase 2 1.01663
TRIM25 tripartite motif containing 25 1.01625
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.01587
PPP1R15B protein phosphatase 1, regulatory subunit 15B 1.01549
ARRB2 arrestin, beta 2 1.01437
CCKBR cholecystokinin B receptor 1.01437
ADCK3 aarF domain containing kinase 3 1.01399
CXCR4 chemokine (C-X-C motif) receptor 4 1.01286
TSHB thyroid stimulating hormone, beta 1.01137
CKB creatine kinase, brain 1.01099