Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

375 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
ACBD3 acyl-CoA binding domain containing 3
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGB androglobin
AGBL3 ATP/GTP binding protein-like 3
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
ALAD aminolevulinate dehydratase
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKIB1 ankyrin repeat and IBR domain containing 1
ANKRD7 ankyrin repeat domain 7
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANLN anillin, actin binding protein
AOC2 amine oxidase, copper containing 2 (retina-specific)
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
ARL4A ADP-ribosylation factor-like 4A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATG4C autophagy related 4C, cysteine peptidase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAG4 BCL2-associated athanogene 4
BANF2 barrier to autointegration factor 2
BCAN brevican
BCHE butyrylcholinesterase
BCL7B B-cell CLL/lymphoma 7B
BCLAF1 BCL2-associated transcription factor 1
BLCAP bladder cancer associated protein
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
C14ORF37 chromosome 14 open reading frame 37
C19ORF71 chromosome 19 open reading frame 71
C1ORF53 chromosome 1 open reading frame 53
C4ORF19 chromosome 4 open reading frame 19
C7ORF49 chromosome 7 open reading frame 49
C9ORF156 chromosome 9 open reading frame 156
C9ORF43 chromosome 9 open reading frame 43
CA4 carbonic anhydrase IV
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADPS2 Ca++-dependent secretion activator 2
CASD1 CAS1 domain containing 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBLN2 cerebellin 2 precursor
CBX3 chromobox homolog 3
CCDC132 coiled-coil domain containing 132
CCDC141 coiled-coil domain containing 141
CCDC169 coiled-coil domain containing 169
CCNH cyclin H
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDHR2 cadherin-related family member 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CELF5 CUGBP, Elav-like family member 5
CENPW centromere protein W
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHD3 chromodomain helicase DNA binding protein 3
CHERP calcium homeostasis endoplasmic reticulum protein
CNOT4 CCR4-NOT transcription complex, subunit 4
CNOT7 CCR4-NOT transcription complex, subunit 7
COX19 COX19 cytochrome c oxidase assembly factor
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRCP CGRP receptor component
CRHR2 corticotropin releasing hormone receptor 2
CTH cystathionine gamma-lyase
CYCSP52 cytochrome c, somatic pseudogene 52
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYTH3 cytohesin 3
DBF4 DBF4 zinc finger
DEPDC4 DEP domain containing 4
DGKI diacylglycerol kinase, iota
DLD dihydrolipoamide dehydrogenase
DLX4 distal-less homeobox 4
DPY19L2P2 DPY19L2 pseudogene 2
DSTYK dual serine/threonine and tyrosine protein kinase
DTD2 D-tyrosyl-tRNA deacylase 2 (putative)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DTWD2 DTW domain containing 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
E2F3 E2F transcription factor 3
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EHD4 EH-domain containing 4
ELOVL5 ELOVL fatty acid elongase 5
EMX1 empty spiracles homeobox 1
ESRP1 epithelial splicing regulatory protein 1
EXO1 exonuclease 1
EXOC8 exocyst complex component 8
FAM120C family with sequence similarity 120C
FAM126A family with sequence similarity 126, member A
FAM133B family with sequence similarity 133, member B
FAM149A family with sequence similarity 149, member A
FASN fatty acid synthase
FBXO9 F-box protein 9
FBXW8 F-box and WD repeat domain containing 8
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FITM2 fat storage-inducing transmembrane protein 2
FKBP14 FK506 binding protein 14, 22 kDa
FKBP15 FK506 binding protein 15, 133kDa
FOXK1 forkhead box K1
FOXN4 forkhead box N4
FRK fyn-related Src family tyrosine kinase
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GARS glycyl-tRNA synthetase
GAS2L3 growth arrest-specific 2 like 3
GCC1 GRIP and coiled-coil domain containing 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRA2 glycine receptor, alpha 2
GMPR guanosine monophosphate reductase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNRHR gonadotropin-releasing hormone receptor
GPR135 G protein-coupled receptor 135
GPR89B G protein-coupled receptor 89B
GPX8 glutathione peroxidase 8 (putative)
GSK3B glycogen synthase kinase 3 beta
GTF2A1L general transcription factor IIA, 1-like
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
H2AFV H2A histone family, member V
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAR1B highly accelerated region 1B (non-protein coding)
HBS1L HBS1-like translational GTPase
HDDC2 HD domain containing 2
HIATL1 hippocampus abundant transcript-like 1
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIST1H2BB histone cluster 1, H2bb
HIST3H3 histone cluster 3, H3
HMBOX1 homeobox containing 1
HOXA11 homeobox A11
HOXD1 homeobox D1
HSPA4 heat shock 70kDa protein 4
HUS1 HUS1 checkpoint homolog (S. pombe)
IER5 immediate early response 5
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INTS9 integrator complex subunit 9
IRF4 interferon regulatory factor 4
ISPD isoprenoid synthase domain containing
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD20 potassium channel tetramerization domain containing 20
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1456 KIAA1456
KIAA1715 KIAA1715
KIF3A kinesin family member 3A
KLHDC10 kelch domain containing 10
KLHL15 kelch-like family member 15
KMT2E lysine (K)-specific methyltransferase 2E
KRIT1 KRIT1, ankyrin repeat containing
KRT24 keratin 24, type I
KRTAP20-2 keratin associated protein 20-2
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LCNL1 lipocalin-like 1
LGI3 leucine-rich repeat LGI family, member 3
LHX2 LIM homeobox 2
LINC00244 long intergenic non-protein coding RNA 244
LMO3 LIM domain only 3 (rhombotin-like 2)
LNP1 leukemia NUP98 fusion partner 1
LOC401463 uncharacterized LOC401463
LOC493754
LOC646762 uncharacterized LOC646762
LOC90246 uncharacterized LOC90246
LONRF1 LON peptidase N-terminal domain and ring finger 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC16A leucine rich repeat containing 16A
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUZP6 leucine zipper protein 6
LYST lysosomal trafficking regulator
MAGED1 melanoma antigen family D1
MALSU1 mitochondrial assembly of ribosomal large subunit 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK10 mitogen-activated protein kinase 10
MED23 mediator complex subunit 23
MET MET proto-oncogene, receptor tyrosine kinase
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MID2 midline 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOCS3 molybdenum cofactor synthesis 3
MREG melanoregulin
MRPL32 mitochondrial ribosomal protein L32
MRPL44 mitochondrial ribosomal protein L44
MYO10 myosin X
MYO5A myosin VA (heavy chain 12, myoxin)
NAMPT nicotinamide phosphoribosyltransferase
NAP1L3 nucleosome assembly protein 1-like 3
NCAPG2 non-SMC condensin II complex, subunit G2
NDUFA4 NDUFA4, mitochondrial complex associated
NFE2L2 nuclear factor, erythroid 2-like 2
NFYA nuclear transcription factor Y, alpha
NHLRC4 NHL repeat containing 4
NHSL1 NHS-like 1
NKX2-4 NK2 homeobox 4
NPSR1 neuropeptide S receptor 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NSF N-ethylmaleimide-sensitive factor
NT5DC1 5'-nucleotidase domain containing 1
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN4 opsin 4
OR10A5 olfactory receptor, family 10, subfamily A, member 5
OR14I1 olfactory receptor, family 14, subfamily I, member 1
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR4F6 olfactory receptor, family 4, subfamily F, member 6
OR7C2 olfactory receptor, family 7, subfamily C, member 2
ORC5 origin recognition complex, subunit 5
OTX1 orthodenticle homeobox 1
PBK PDZ binding kinase
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCDHGA7 protocadherin gamma subfamily A, 7
PCDHGB5 protocadherin gamma subfamily B, 5
PDE3A phosphodiesterase 3A, cGMP-inhibited
PEX7 peroxisomal biogenesis factor 7
PGM2 phosphoglucomutase 2
PHTF2 putative homeodomain transcription factor 2
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PMS2CL PMS2 C-terminal like pseudogene
PNMA2 paraneoplastic Ma antigen 2
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
POMZP3 POM121 and ZP3 fusion
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCE protein kinase C, epsilon
PRLH prolactin releasing hormone
PRRC1 proline-rich coiled-coil 1
PRRT4 proline-rich transmembrane protein 4
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTCD3 pentatricopeptide repeat domain 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PURB purine-rich element binding protein B
QPRT quinolinate phosphoribosyltransferase
RAP2B RAP2B, member of RAS oncogene family
RBAK RB-associated KRAB zinc finger
RBM48 RNA binding motif protein 48
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGS12 regulator of G-protein signaling 12
RGS20 regulator of G-protein signaling 20
RINT1 RAD50 interactor 1
RNF146 ring finger protein 146
RNF216 ring finger protein 216
RNF216P1 ring finger protein 216 pseudogene 1
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RP1L1 retinitis pigmentosa 1-like 1
RPS12 ribosomal protein S12
RTN4RL1 reticulon 4 receptor-like 1
SAMD4A sterile alpha motif domain containing 4A
SAXO2 stabilizer of axonemal microtubules 2
SBDS Shwachman-Bodian-Diamond syndrome
SCFD2 sec1 family domain containing 2
SDCBP syndecan binding protein (syntenin)
SELENBP1 selenium binding protein 1
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEPT7P2 septin 7 pseudogene 2
SGK223 homolog of rat pragma of Rnd2
SLC18B1 solute carrier family 18, subfamily B, member 1
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A40 solute carrier family 25, member 40
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC35D3 solute carrier family 35, member D3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMIM7 small integral membrane protein 7
SNAI2 snail family zinc finger 2
SNHG15 small nucleolar RNA host gene 15
SNORA22 small nucleolar RNA, H/ACA box 22
SNORA24 small nucleolar RNA, H/ACA box 24
SNORA29 small nucleolar RNA, H/ACA box 29
SNORA75 small nucleolar RNA, H/ACA box 75
SNORD116-20 small nucleolar RNA, C/D box 116-20
SNTG1 syntrophin, gamma 1
SNX13 sorting nexin 13
SPRY3 sprouty homolog 3 (Drosophila)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRPK2 SRSF protein kinase 2
SSH2 slingshot protein phosphatase 2
ST7-OT3 ST7 overlapping transcript 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD3NL STARD3 N-terminal like
STON1 stonin 1
STRADB STE20-related kinase adaptor beta
STX7 syntaxin 7
SUCNR1 succinate receptor 1
SYPL1 synaptophysin-like 1
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TAS2R19 taste receptor, type 2, member 19
TAS2R31 taste receptor, type 2, member 31
TBL2 transducin (beta)-like 2
TCAF1 TRPM8 channel-associated factor 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDRD7 tudor domain containing 7
TEX15 testis expressed 15
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TGS1 trimethylguanosine synthase 1
THEM4 thioesterase superfamily member 4
TM2D2 TM2 domain containing 2
TM6SF2 transmembrane 6 superfamily member 2
TMEM140 transmembrane protein 140
TMEM168 transmembrane protein 168
TMEM248 transmembrane protein 248
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNNI3 troponin I type 3 (cardiac)
TNPO3 transportin 3
TP53TG1 TP53 target 1 (non-protein coding)
TPMT thiopurine S-methyltransferase
TRIB1 tribbles pseudokinase 1
TRIM16L tripartite motif containing 16-like
TRIM4 tripartite motif containing 4
TRIM61 tripartite motif containing 61
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSC22D4 TSC22 domain family, member 4
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TSPYL1 TSPY-like 1
TSPYL4 TSPY-like 4
TTPA tocopherol (alpha) transfer protein
TUBB1 tubulin, beta 1 class VI
TWISTNB TWIST neighbor
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBXN8 UBX domain protein 8
UGCG UDP-glucose ceramide glucosyltransferase
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UNC79 unc-79 homolog (C. elegans)
URGCP upregulator of cell proliferation
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VSTM2L V-set and transmembrane domain containing 2 like
VTA1 vesicle (multivesicular body) trafficking 1
WDR37 WD repeat domain 37
WDR60 WD repeat domain 60
WSB2 WD repeat and SOCS box containing 2
XKR6 XK, Kell blood group complex subunit-related family, member 6
XPO7 exportin 7
YIPF7 Yip1 domain family, member 7
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZC3H7A zinc finger CCCH-type containing 7A
ZC3HC1 zinc finger, C3HC-type containing 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMAT3 zinc finger, matrin-type 3
ZNF106 zinc finger protein 106
ZNF12 zinc finger protein 12
ZNF268 zinc finger protein 268
ZNF433 zinc finger protein 433
ZNF578 zinc finger protein 578
ZNF582 zinc finger protein 582
ZNF596 zinc finger protein 596
ZNF658 zinc finger protein 658
ZNF665 zinc finger protein 665
ZNF669 zinc finger protein 669
ZSCAN25 zinc finger and SCAN domain containing 25

low expression

Symbol Name
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)