Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

437 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABLIM1 actin binding LIM protein 1
ABR active BCR-related
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ADAM23 ADAM metallopeptidase domain 23
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADCY9 adenylate cyclase 9
ADD3 adducin 3 (gamma)
ADRA2C adrenoceptor alpha 2C
ADSL adenylosuccinate lyase
AJAP1 adherens junctions associated protein 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMDHD2 amidohydrolase domain containing 2
AMMECR1L AMMECR1-like
ANK2 ankyrin 2, neuronal
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD17 ankyrin repeat domain 17
ANKRD23 ankyrin repeat domain 23
ANKRD39 ankyrin repeat domain 39
ANKRD52 ankyrin repeat domain 52
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AP3M1 adaptor-related protein complex 3, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APCDD1 adenomatosis polyposis coli down-regulated 1
ARF6 ADP-ribosylation factor 6
ARHGAP24 Rho GTPase activating protein 24
ARHGAP32 Rho GTPase activating protein 32
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX3 armadillo repeat containing, X-linked 3
ARMCX6 armadillo repeat containing, X-linked 6
ARSG arylsulfatase G
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ARX aristaless related homeobox
ASXL1 additional sex combs like transcriptional regulator 1
ATG14 autophagy related 14
ATG2A autophagy related 2A
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATRN attractin
AXIN2 axin 2
B3GALTL beta 1,3-galactosyltransferase-like
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAIAP2L2 BAI1-associated protein 2-like 2
BBC3 BCL2 binding component 3
BBS1 Bardet-Biedl syndrome 1
BCORL1 BCL6 corepressor-like 1
BOK BCL2-related ovarian killer
BTBD10 BTB (POZ) domain containing 10
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C15ORF59 chromosome 15 open reading frame 59
C1ORF101 chromosome 1 open reading frame 101
C1ORF198 chromosome 1 open reading frame 198
C2ORF88 chromosome 2 open reading frame 88
C4ORF47 chromosome 4 open reading frame 47
C9ORF129 chromosome 9 open reading frame 129
CA14 carbonic anhydrase XIV
CACHD1 cache domain containing 1
CBX6 chromobox homolog 6
CBY1 chibby homolog 1 (Drosophila)
CCDC184 coiled-coil domain containing 184
CCDC43 coiled-coil domain containing 43
CCDC80 coiled-coil domain containing 80
CCNT1 cyclin T1
CDC25B cell division cycle 25B
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK15 cyclin-dependent kinase 15
CDYL chromodomain protein, Y-like
CELA2B chymotrypsin-like elastase family, member 2B
CELF2 CUGBP, Elav-like family member 2
CEMP1 cementum protein 1
CHD6 chromodomain helicase DNA binding protein 6
CHMP1B charged multivesicular body protein 1B
CHURC1 churchill domain containing 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
CISD1 CDGSH iron sulfur domain 1
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLASP1 cytoplasmic linker associated protein 1
CLCN7 chloride channel, voltage-sensitive 7
CLEC12B C-type lectin domain family 12, member B
CLIP1 CAP-GLY domain containing linker protein 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRMP1 collapsin response mediator protein 1
CROT carnitine O-octanoyltransferase
CRYM crystallin, mu
CSNK1E casein kinase 1, epsilon
CST1 cystatin SN
CST4 cystatin S
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNND1 catenin (cadherin-associated protein), delta 1
CTXN1 cortexin 1
CYB561A3 cytochrome b561 family, member A3
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBN1 drebrin 1
DENND5B DENN/MADD domain containing 5B
DERA deoxyribose-phosphate aldolase (putative)
DIRC2 disrupted in renal carcinoma 2
DKFZP434H168 uncharacterized LOC26077
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNAL4 dynein, axonemal, light chain 4
DOCK5 dedicator of cytokinesis 5
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPYSL2 dihydropyrimidinase-like 2
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP16 dual specificity phosphatase 16
DUSP8 dual specificity phosphatase 8
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDNRB endothelin receptor type B
EMP1 epithelial membrane protein 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EOMES eomesodermin
EPHA5 EPH receptor A5
EPHB1 EPH receptor B1
ETV5 ets variant 5
EXOC6B exocyst complex component 6B
EXTL3 exostosin-like glycosyltransferase 3
FAHD1 fumarylacetoacetate hydrolase domain containing 1
FAM101B family with sequence similarity 101, member B
FAM149B1 family with sequence similarity 149, member B1
FAM161A family with sequence similarity 161, member A
FAM21A family with sequence similarity 21, member A
FAM53C family with sequence similarity 53, member C
FAM89A family with sequence similarity 89, member A
FASTKD3 FAST kinase domains 3
FASTKD5 FAST kinase domains 5
FBXL20 F-box and leucine-rich repeat protein 20
FER fer (fps/fes related) tyrosine kinase
FER1L6 fer-1-like family member 6
FHOD3 formin homology 2 domain containing 3
FIGN fidgetin
FITM2 fat storage-inducing transmembrane protein 2
FOCAD focadhesin
FOXO4 forkhead box O4
FSTL1 follistatin-like 1
FSTL5 follistatin-like 5
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GAS6 growth arrest-specific 6
GCC1 GRIP and coiled-coil domain containing 1
GJB1 gap junction protein, beta 1, 32kDa
GMPR guanosine monophosphate reductase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR143 G protein-coupled receptor 143
GSG1L GSG1-like
GSK3B glycogen synthase kinase 3 beta
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTPBP1 GTP binding protein 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBP1 HMG-box transcription factor 1
HEXA-AS1 HEXA antisense RNA 1
HIATL1 hippocampus abundant transcript-like 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H3E histone cluster 1, H3e
HMBOX1 homeobox containing 1
HNMT histamine N-methyltransferase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRH3 histamine receptor H3
HS1BP3 HCLS1 binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSDL1 hydroxysteroid dehydrogenase like 1
HSPA1L heat shock 70kDa protein 1-like
IFNW1 interferon, omega 1
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IL16 interleukin 16
ILK integrin-linked kinase
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPMK inositol polyphosphate multikinase
IRAK3 interleukin-1 receptor-associated kinase 3
IRF4 interferon regulatory factor 4
IRGQ immunity-related GTPase family, Q
IRS2 insulin receptor substrate 2
IRX2 iroquois homeobox 2
JOSD1 Josephin domain containing 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0100 KIAA0100
KIAA0754 KIAA0754
KIAA1211 KIAA1211
KIAA1549L KIAA1549-like
KIF16B kinesin family member 16B
KIF1A kinesin family member 1A
KIF1B kinesin family member 1B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL9 kelch-like family member 9
KRBA2 KRAB-A domain containing 2
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LATS2 large tumor suppressor kinase 2
LIMD1 LIM domains containing 1
LINC00518 long intergenic non-protein coding RNA 518
LINGO1 leucine rich repeat and Ig domain containing 1
LOC100129550 uncharacterized LOC100129550
LPPR4 lipid phosphate phosphatase-related protein type 4
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC27 leucine rich repeat containing 27
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LY6G6F lymphocyte antigen 6 complex, locus G6F
MAEA macrophage erythroblast attacher
MANEAL mannosidase, endo-alpha-like
MAP4 microtubule-associated protein 4
MAP6 microtubule-associated protein 6
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARVELD2 MARVEL domain containing 2
MAVS mitochondrial antiviral signaling protein
MBD3L1 methyl-CpG binding domain protein 3-like 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCF2L MCF.2 cell line derived transforming sequence-like
MCTS2P malignant T cell amplified sequence 2, pseudogene
MED18 mediator complex subunit 18
MED20 mediator complex subunit 20
METTL12 methyltransferase like 12
MGME1 mitochondrial genome maintenance exonuclease 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLANA melan-A
MLEC malectin
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPPE1 metallophosphoesterase 1
MRPS16 mitochondrial ribosomal protein S16
MSI2 musashi RNA-binding protein 2
MTCH2 mitochondrial carrier 2
MTG2 mitochondrial ribosome-associated GTPase 2
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MXD4 MAX dimerization protein 4
MYO1D myosin ID
MYO5A myosin VA (heavy chain 12, myoxin)
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NAT8L N-acetyltransferase 8-like (GCN5-related, putative)
NATD1 N-acetyltransferase domain containing 1
NBEAL1 neurobeachin-like 1
NECAB2 N-terminal EF-hand calcium binding protein 2
NHLRC2 NHL repeat containing 2
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NKD1 naked cuticle homolog 1 (Drosophila)
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NOP9 NOP9 nucleolar protein
NPHP4 nephronophthisis 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NSG1 neuron specific gene family member 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
ONECUT2 one cut homeobox 2
OR1E2 olfactory receptor, family 1, subfamily E, member 2
OTOF otoferlin
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PALM paralemmin
PANK3 pantothenate kinase 3
PAQR8 progestin and adipoQ receptor family member VIII
PARVA parvin, alpha
PAX3 paired box 3
PCDHA11 protocadherin alpha 11
PCDHA12 protocadherin alpha 12
PCDHA5 protocadherin alpha 5
PDDC1 Parkinson disease 7 domain containing 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PDZD8 PDZ domain containing 8
PEG3 paternally expressed 3
PEG3-AS1 PEG3 antisense RNA 1
PGBD5 piggyBac transposable element derived 5
PHACTR3 phosphatase and actin regulator 3
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PICK1 protein interacting with PRKCA 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLA2G15 phospholipase A2, group XV
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHM3 pleckstrin homology domain containing, family M, member 3
PNMA6A paraneoplastic Ma antigen family member 6A
PNRC1 proline-rich nuclear receptor coactivator 1
POU4F3 POU class 4 homeobox 3
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene)
PRKD1 protein kinase D1
PRKD3 protein kinase D3
PRR14L proline rich 14-like
PRUNE2 prune homolog 2 (Drosophila)
PSEN2 presenilin 2
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRM protein tyrosine phosphatase, receptor type, M
PTPRS protein tyrosine phosphatase, receptor type, S
PXK PX domain containing serine/threonine kinase
PXMP4 peroxisomal membrane protein 4, 24kDa
QPCT glutaminyl-peptide cyclotransferase
QPRT quinolinate phosphoribosyltransferase
RAB7A RAB7A, member RAS oncogene family
RABIF RAB interacting factor
RANBP10 RAN binding protein 10
RAP2B RAP2B, member of RAS oncogene family
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBBP9 retinoblastoma binding protein 9
RBM12 RNA binding motif protein 12
RC3H2 ring finger and CCCH-type domains 2
REPS2 RALBP1 associated Eps domain containing 2
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RGS3 regulator of G-protein signaling 3
RGS9BP regulator of G protein signaling 9 binding protein
RHOA ras homolog family member A
RHOB ras homolog family member B
RMDN2 regulator of microtubule dynamics 2
RNF144B ring finger protein 144B
RPS6KL1 ribosomal protein S6 kinase-like 1
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRAGA Ras-related GTP binding A
RTTN rotatin
SARM1 sterile alpha and TIR motif containing 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGSM3 small G protein signaling modulator 3
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A6 solute carrier family 16, member 6
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A23 solute carrier family 22, member 23
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC35A5 solute carrier family 35, member A5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC45A3 solute carrier family 45, member 3
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLITRK2 SLIT and NTRK-like family, member 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX19 sorting nexin 19
SNX25 sorting nexin 25
SNX30 sorting nexin family member 30
SOCS6 suppressor of cytokine signaling 6
SOX12 SRY (sex determining region Y)-box 12
SP5 Sp5 transcription factor
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRPK2 SRSF protein kinase 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STXBP6 syntaxin binding protein 6 (amisyn)
SYNGR1 synaptogyrin 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D16 TBC1 domain family, member 16
TBC1D20 TBC1 domain family, member 20
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TECPR2 tectonin beta-propeller repeat containing 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TJP1 tight junction protein 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLL2 tolloid-like 2
TM4SF20 transmembrane 4 L six family member 20
TMEM110 transmembrane protein 110
TMEM138 transmembrane protein 138
TMEM184B transmembrane protein 184B
TMEM204 transmembrane protein 204
TMEM63B transmembrane protein 63B
TMOD1 tropomodulin 1
TMPPE transmembrane protein with metallophosphoesterase domain
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNPO2 transportin 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TP53I11 tumor protein p53 inducible protein 11
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPCN2 two pore segment channel 2
TPP1 tripeptidyl peptidase I
TRAK2 trafficking protein, kinesin binding 2
TRIM32 tripartite motif containing 32
TRIO trio Rho guanine nucleotide exchange factor
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSGA10IP testis specific, 10 interacting protein
TTYH2 tweety family member 2
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TYR tyrosinase
TYRP1 tyrosinase-related protein 1
UBE2H ubiquitin-conjugating enzyme E2H
UBFD1 ubiquitin family domain containing 1
UNC13B unc-13 homolog B (C. elegans)
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VEPH1 ventricular zone expressed PH domain-containing 1
VLDLR very low density lipoprotein receptor
WDR20 WD repeat domain 20
WNT4 wingless-type MMTV integration site family, member 4
WSB2 WD repeat and SOCS box containing 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZC3H10 zinc finger CCCH-type containing 10
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZEB2 zinc finger E-box binding homeobox 2
ZFP69B ZFP69 zinc finger protein B
ZFYVE21 zinc finger, FYVE domain containing 21
ZIM2 zinc finger, imprinted 2
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMAT3 zinc finger, matrin-type 3
ZNF134 zinc finger protein 134
ZNF135 zinc finger protein 135
ZNF197 zinc finger protein 197
ZNF320 zinc finger protein 320
ZNF416 zinc finger protein 416
ZNF417 zinc finger protein 417
ZNF549 zinc finger protein 549
ZNF562 zinc finger protein 562
ZNF619 zinc finger protein 619
ZNF649 zinc finger protein 649
ZNF749 zinc finger protein 749
ZNF772 zinc finger protein 772
ZSWIM1 zinc finger, SWIM-type containing 1