Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZB-06A-12R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

377 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZB-06A-12R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACPT acid phosphatase, testicular
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
AHNAK AHNAK nucleoprotein
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AMOTL1 angiomotin like 1
AOC3 amine oxidase, copper containing 3
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APCDD1 adenomatosis polyposis coli down-regulated 1
APOBR apolipoprotein B receptor
AQP9 aquaporin 9
ARHGAP10 Rho GTPase activating protein 10
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ASB13 ankyrin repeat and SOCS box containing 13
ASB2 ankyrin repeat and SOCS box containing 2
ATF3 activating transcription factor 3
ATL3 atlastin GTPase 3
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
AURKB aurora kinase B
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BEST2 bestrophin 2
BICC1 BicC family RNA binding protein 1
BMP2K BMP2 inducible kinase
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BPIFA1 BPI fold containing family A, member 1
BRI3BP BRI3 binding protein
BRMS1 breast cancer metastasis suppressor 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTBD6 BTB (POZ) domain containing 6
C11ORF84 chromosome 11 open reading frame 84
C15ORF43 chromosome 15 open reading frame 43
C1ORF115 chromosome 1 open reading frame 115
C1ORF68 chromosome 1 open reading frame 68
C1QTNF1 C1q and tumor necrosis factor related protein 1
C2ORF72 chromosome 2 open reading frame 72
C5AR1 complement component 5a receptor 1
C8ORF74 chromosome 8 open reading frame 74
CACHD1 cache domain containing 1
CALHM1 calcium homeostasis modulator 1
CALHM2 calcium homeostasis modulator 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAPN1 calpain 1, (mu/I) large subunit
CARD16 caspase recruitment domain family, member 16
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC51 coiled-coil domain containing 51
CCDC85B coiled-coil domain containing 85B
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL27 chemokine (C-C motif) ligand 27
CCND1 cyclin D1
CD1A CD1a molecule
CD248 CD248 molecule, endosialin
CD300E CD300e molecule
CD300LB CD300 molecule-like family member b
CD300LG CD300 molecule-like family member g
CD34 CD34 molecule
CD93 CD93 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDCA2 cell division cycle associated 2
CDCA5 cell division cycle associated 5
CDCP1 CUB domain containing protein 1
CDH22 cadherin 22, type 2
CDH23 cadherin-related 23
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR1 cadherin-related family member 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDX4 caudal type homeobox 4
CDY2B chromodomain protein, Y-linked, 2B
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFL1 cofilin 1 (non-muscle)
CHP2 calcineurin-like EF-hand protein 2
CISD1 CDGSH iron sulfur domain 1
CLDN8 claudin 8
CLEC14A C-type lectin domain family 14, member A
CLEC2A C-type lectin domain family 2, member A
CLEC3B C-type lectin domain family 3, member B
CLEC5A C-type lectin domain family 5, member A
CLP1 cleavage and polyadenylation factor I subunit 1
CMA1 chymase 1, mast cell
CNIH2 cornichon family AMPA receptor auxiliary protein 2
COL17A1 collagen, type XVII, alpha 1
COL21A1 collagen, type XXI, alpha 1
COLEC12 collectin sub-family member 12
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CTNND1 catenin (cadherin-associated protein), delta 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYTH3 cytohesin 3
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCLRE1B DNA cross-link repair 1B
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB136 defensin, beta 136
DEGS1 delta(4)-desaturase, sphingolipid 1
DGKG diacylglycerol kinase, gamma 90kDa
DHDH dihydrodiol dehydrogenase (dimeric)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DPP3 dipeptidyl-peptidase 3
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DTX4 deltex 4, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
E2F2 E2F transcription factor 2
EEF2K eukaryotic elongation factor 2 kinase
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EHD1 EH-domain containing 1
EIF1AD eukaryotic translation initiation factor 1A domain containing
ENDOD1 endonuclease domain containing 1
EPAS1 endothelial PAS domain protein 1
ESRRA estrogen-related receptor alpha
ESYT1 extended synaptotagmin-like protein 1
EVA1C eva-1 homolog C (C. elegans)
EXPH5 exophilin 5
FAIM Fas apoptotic inhibitory molecule
FAM111B family with sequence similarity 111, member B
FAM162B family with sequence similarity 162, member B
FAM43B family with sequence similarity 43, member B
FAM57A family with sequence similarity 57, member A
FAM89B family with sequence similarity 89, member B
FAP fibroblast activation protein, alpha
FBLN2 fibulin 2
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FDXR ferredoxin reductase
FEN1 flap structure-specific endonuclease 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FKBP2 FK506 binding protein 2, 13kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOXQ1 forkhead box Q1
FPR3 formyl peptide receptor 3
FRMD8 FERM domain containing 8
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GAMT guanidinoacetate N-methyltransferase
GAS2L1 growth arrest-specific 2 like 1
GATA3 GATA binding protein 3
GBX2 gastrulation brain homeobox 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GFRAL GDNF family receptor alpha like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRTP1 growth hormone regulated TBC protein 1
GSTM1 glutathione S-transferase mu 1
HAP1 huntingtin-associated protein 1
HIST1H1A histone cluster 1, H1a
HK1 hexokinase 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HN1L hematological and neurological expressed 1-like
HOMER2 homer scaffolding protein 2
HOXC5 homeobox C5
HPGDS hematopoietic prostaglandin D synthase
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNLR1 interferon, lambda receptor 1
IL20RB interleukin 20 receptor beta
IL37 interleukin 37
INF2 inverted formin, FH2 and WH2 domain containing
INO80C INO80 complex subunit C
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IQCF5 IQ motif containing F5
IQSEC1 IQ motif and Sec7 domain 1
JUNB jun B proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK16 potassium channel, two pore domain subfamily K, member 16
KHK ketohexokinase (fructokinase)
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLF4 Kruppel-like factor 4 (gut)
KLK4 kallikrein-related peptidase 4
KRT15 keratin 15, type I
KRT77 keratin 77, type II
KRTAP21-2 keratin associated protein 21-2
KY kyphoscoliosis peptidase
LAMB4 laminin, beta 4
LCE5A late cornified envelope 5A
LGMN legumain
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LIMD1 LIM domains containing 1
LINC00341 long intergenic non-protein coding RNA 341
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LTK leukocyte receptor tyrosine kinase
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MCEMP1 mast cell-expressed membrane protein 1
MED17 mediator complex subunit 17
MED19 mediator complex subunit 19
MEDAG mesenteric estrogen-dependent adipogenesis
MEGF6 multiple EGF-like-domains 6
MEN1 multiple endocrine neoplasia I
METTL9 methyltransferase like 9
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP27 matrix metallopeptidase 27
MMP28 matrix metallopeptidase 28
MMRN2 multimerin 2
MNX1 motor neuron and pancreas homeobox 1
MOV10 Mov10 RISC complex RNA helicase
MRPL49 mitochondrial ribosomal protein L49
MT4 metallothionein 4
MTA2 metastasis associated 1 family, member 2
MUS81 MUS81 structure-specific endonuclease subunit
MYOCD myocardin
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NAT8L N-acetyltransferase 8-like (GCN5-related, putative)
NCF2 neutrophil cytosolic factor 2
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NEUROD2 neuronal differentiation 2
NLRP12 NLR family, pyrin domain containing 12
NOX4 NADPH oxidase 4
NPTX1 neuronal pentraxin I
NPY4R neuropeptide Y receptor Y4
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
OIT3 oncoprotein induced transcript 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OR1E2 olfactory receptor, family 1, subfamily E, member 2
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR4D10 olfactory receptor, family 4, subfamily D, member 10
OR52I1 olfactory receptor, family 52, subfamily I, member 1
OSBP oxysterol binding protein
OSBPL3 oxysterol binding protein-like 3
OSR2 odd-skipped related transciption factor 2
OTOP1 otopetrin 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
OVCH2 ovochymase 2 (gene/pseudogene)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PAX6 paired box 6
PCNA proliferating cell nuclear antigen
PCNXL3 pecanex-like 3 (Drosophila)
PCP4 Purkinje cell protein 4
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
PGAM1 phosphoglycerate mutase 1 (brain)
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PI16 peptidase inhibitor 16
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PICALM phosphatidylinositol binding clathrin assembly protein
PIDD1 p53-induced death domain protein 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLA2G16 phospholipase A2, group XVI
PLAC9 placenta-specific 9
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLK3 polo-like kinase 3
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POU2F3 POU class 2 homeobox 3
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRDM4 PR domain containing 4
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRG4 proteoglycan 4
PTGFRN prostaglandin F2 receptor inhibitor
PTRF polymerase I and transcript release factor
PWRN2 Prader-Willi region non-protein coding RNA 2
RAB38 RAB38, member RAS oncogene family
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASA4 RAS p21 protein activator 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELT RELT tumor necrosis factor receptor
RETN resistin
RGCC regulator of cell cycle
RIN1 Ras and Rab interactor 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASEH2C ribonuclease H2, subunit C
RNF182 ring finger protein 182
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRM2 ribonucleotide reductase M2
RTN3 reticulon 3
RTN4RL1 reticulon 4 receptor-like 1
SAC3D1 SAC3 domain containing 1
SCYL1 SCY1-like 1 (S. cerevisiae)
SDHAF2 succinate dehydrogenase complex assembly factor 2
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFXN2 sideroflexin 2
SFXN3 sideroflexin 3
SGPL1 sphingosine-1-phosphate lyase 1
SH3BP4 SH3-domain binding protein 4
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC43A3 solute carrier family 43, member 3
SLC46A2 solute carrier family 46, member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SMAD5-AS1 SMAD5 antisense RNA 1
SMCO2 single-pass membrane protein with coiled-coil domains 2
SNORA4 small nucleolar RNA, H/ACA box 4
SNORA61 small nucleolar RNA, H/ACA box 61
SNTG2 syntrophin, gamma 2
SNX15 sorting nexin 15
SOX18 SRY (sex determining region Y)-box 18
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SRSF8 serine/arginine-rich splicing factor 8
SSRP1 structure specific recognition protein 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STIP1 stress-induced phosphoprotein 1
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYT8 synaptotagmin VIII
SYTL2 synaptotagmin-like 2
TACR1 tachykinin receptor 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAS2R41 taste receptor, type 2, member 41
TAT tyrosine aminotransferase
TEC tec protein tyrosine kinase
TIGD3 tigger transposable element derived 3
TKFC triokinase/FMN cyclase
TM7SF2 transmembrane 7 superfamily member 2
TMEM109 transmembrane protein 109
TMEM138 transmembrane protein 138
TMEM163 transmembrane protein 163
TMEM179B transmembrane protein 179B
TMEM204 transmembrane protein 204
TMEM52 transmembrane protein 52
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TNXB tenascin XB
TP53I3 tumor protein p53 inducible protein 3
TPPP3 tubulin polymerization-promoting protein family member 3
TPSAB1 tryptase alpha/beta 1
TRIM7 tripartite motif containing 7
TRIM8 tripartite motif containing 8
TRPT1 tRNA phosphotransferase 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSKU tsukushi, small leucine rich proteoglycan
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UNC93B1 unc-93 homolog B1 (C. elegans)
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3
USP31 ubiquitin specific peptidase 31
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR63 WD repeat domain 63
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WWC1 WW and C2 domain containing 1
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
YAP1 Yes-associated protein 1
ZBTB16 zinc finger and BTB domain containing 16
ZBTB3 zinc finger and BTB domain containing 3
ZDHHC5 zinc finger, DHHC-type containing 5
ZFP36 ZFP36 ring finger protein
ZNF366 zinc finger protein 366
ZWINT ZW10 interacting kinetochore protein