Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

361 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARD alanine and arginine rich domain containing protein
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
ACTL7B actin-like 7B
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY4 adenylate cyclase 4
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL4 adhesion G protein-coupled receptor L4
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADRA1D adrenoceptor alpha 1D
AGFG2 ArfGAP with FG repeats 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALPK3 alpha-kinase 3
AMH anti-Mullerian hormone
ANGPT2 angiopoietin 2
ANKRD7 ankyrin repeat domain 7
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
ANXA13 annexin A13
AOC3 amine oxidase, copper containing 3
APOL5 apolipoprotein L, 5
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL15 ADP-ribosylation factor-like 15
ARL4A ADP-ribosylation factor-like 4A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCAP29 B-cell receptor-associated protein 29
BCHE butyrylcholinesterase
BCL6B B-cell CLL/lymphoma 6, member B
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C1QTNF9B C1q and tumor necrosis factor related protein 9B
C2ORF88 chromosome 2 open reading frame 88
C5AR1 complement component 5a receptor 1
C7ORF73 chromosome 7 open reading frame 73
CAB39L calcium binding protein 39-like
CALCRL calcitonin receptor-like
CASQ2 calsequestrin 2 (cardiac muscle)
CAV2 caveolin 2
CBX3 chromobox homolog 3
CCDC160 coiled-coil domain containing 160
CCDC50 coiled-coil domain containing 50
CCDC80 coiled-coil domain containing 80
CCM2L cerebral cavernous malformation 2-like
CD200 CD200 molecule
CD300LB CD300 molecule-like family member b
CD302 CD302 molecule
CD34 CD34 molecule
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR2 cadherin-related family member 2
CHL1 cell adhesion molecule L1-like
CHRD chordin
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN1 claudin 1
CLEC14A C-type lectin domain family 14, member A
CLHC1 clathrin heavy chain linker domain containing 1
CLN5 ceroid-lipofuscinosis, neuronal 5
CNN1 calponin 1, basic, smooth muscle
CNPY4 canopy FGF signaling regulator 4
CNTN6 contactin 6
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL3A1 collagen, type III, alpha 1
COMT catechol-O-methyltransferase
CORO2B coronin, actin binding protein, 2B
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CPED1 cadherin-like and PC-esterase domain containing 1
CPLX2 complexin 2
CPN1 carboxypeptidase N, polypeptide 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROT carnitine O-octanoyltransferase
CRYL1 crystallin, lambda 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CTAGE9 CTAGE family, member 9
CTXN2 cortexin 2
CXORF36 chromosome X open reading frame 36
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYYR1 cysteine/tyrosine-rich 1
DCN decorin
DDX26B DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
DEFB109P1B defensin, beta 109, pseudogene 1B
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNM1 dynamin 1
DNMBP-AS1 DNMBP antisense RNA 1
DPY19L2 dpy-19-like 2 (C. elegans)
DPY19L2P4 DPY19L2 pseudogene 4
DRP2 dystrophin related protein 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EBF1 early B-cell factor 1
EDN1 endothelin 1
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELOVL2 ELOVL fatty acid elongase 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERVFRD-1 endogenous retrovirus group FRD, member 1
ESAM endothelial cell adhesion molecule
EXOC3L1 exocyst complex component 3-like 1
EXOC3L2 exocyst complex component 3-like 2
EXOC4 exocyst complex component 4
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM122A family with sequence similarity 122A
FAM13C family with sequence similarity 13, member C
FAM149A family with sequence similarity 149, member A
FAM162B family with sequence similarity 162, member B
FAM170B family with sequence similarity 170, member B
FAM46A family with sequence similarity 46, member A
FAM84B family with sequence similarity 84, member B
FAM95B1 family with sequence similarity 95, member B1
FAT4 FAT atypical cadherin 4
FBXL22 F-box and leucine-rich repeat protein 22
FBXL5 F-box and leucine-rich repeat protein 5
FEM1C fem-1 homolog c (C. elegans)
FGD5 FYVE, RhoGEF and PH domain containing 5
FGF7 fibroblast growth factor 7
FHL5 four and a half LIM domains 5
FILIP1 filamin A interacting protein 1
FILIP1L filamin A interacting protein 1-like
FLT1 fms-related tyrosine kinase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXS1 forkhead box S1
FRK fyn-related Src family tyrosine kinase
FRY furry homolog (Drosophila)
FSTL1 follistatin-like 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GDF10 growth differentiation factor 10
GGT5 gamma-glutamyltransferase 5
GJA3 gap junction protein, alpha 3, 46kDa
GJB2 gap junction protein, beta 2, 26kDa
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR1 G protein-coupled receptor 1
GPR21 G protein-coupled receptor 21
GRIK3 glutamate receptor, ionotropic, kainate 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFV H2A histone family, member V
HACD4 3-hydroxyacyl-CoA dehydratase 4
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HHEX hematopoietically expressed homeobox
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIST1H2BH histone cluster 1, H2bh
HOTAIR HOX transcript antisense RNA
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSBP1 heat shock factor binding protein 1
IFNW1 interferon, omega 1
IL17D interleukin 17D
INE2 inactivation escape 2 (non-protein coding)
ING3 inhibitor of growth family, member 3
IQCK IQ motif containing K
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITLN1 intelectin 1 (galactofuranose binding)
KANK3 KN motif and ankyrin repeat domains 3
KATNAL2 katanin p60 subunit A-like 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD12 potassium channel tetramerization domain containing 12
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KIAA1462 KIAA1462
KLHL20 kelch-like family member 20
KRTAP27-1 keratin associated protein 27-1
LIPI lipase, member I
LMOD1 leiomodin 1 (smooth muscle)
LRP4 low density lipoprotein receptor-related protein 4
LRRC70 leucine rich repeat containing 70
LRRTM1 leucine rich repeat transmembrane neuronal 1
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MFRP membrane frizzled-related protein
MFSD6 major facilitator superfamily domain containing 6
MGC16142 uncharacterized protein MGC16142
MINOS1 mitochondrial inner membrane organizing system 1
MKKS McKusick-Kaufman syndrome
MKRN1 makorin ring finger protein 1
MMP7 matrix metallopeptidase 7
MMRN2 multimerin 2
MN1 meningioma (disrupted in balanced translocation) 1
MOXD1 monooxygenase, DBH-like 1
MRO maestro
MRVI1 murine retrovirus integration site 1 homolog
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTMR7 myotubularin related protein 7
MUSTN1 musculoskeletal, embryonic nuclear protein 1
MYCT1 myc target 1
MYH11 myosin, heavy chain 11, smooth muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO3A myosin IIIA
MYOCD myocardin
MYOM1 myomesin 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NBL1 neuroblastoma 1, DAN family BMP antagonist
NELL1 NEL-like 1 (chicken)
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NFE2L2 nuclear factor, erythroid 2-like 2
NHSL2 NHS-like 2
NID2 nidogen 2 (osteonidogen)
NKAIN3 Na+/K+ transporting ATPase interacting 3
NME5 NME/NM23 family member 5
NOTCH4 notch 4
NRIP2 nuclear receptor interacting protein 2
NUTM2F NUT family member 2F
NUTM2G NUT family member 2G
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
OAZ2 ornithine decarboxylase antizyme 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OIT3 oncoprotein induced transcript 3
OLFM3 olfactomedin 3
OMG oligodendrocyte myelin glycoprotein
OPN3 opsin 3
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2A1 olfactory receptor, family 2, subfamily A, member 1
OR2A12 olfactory receptor, family 2, subfamily A, member 12
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2A25 olfactory receptor, family 2, subfamily A, member 25
OR2A5 olfactory receptor, family 2, subfamily A, member 5
OR2A9P olfactory receptor, family 2, subfamily A, member 9 pseudogene
OR3A1 olfactory receptor, family 3, subfamily A, member 1
OR6P1 olfactory receptor, family 6, subfamily P, member 1
OVCH1 ovochymase 1
PALLD palladin, cytoskeletal associated protein
PAX4 paired box 4
PCDH12 protocadherin 12
PCDHGA3 protocadherin gamma subfamily A, 3
PCOLCE procollagen C-endopeptidase enhancer
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PDGFD platelet derived growth factor D
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX5L peroxisomal biogenesis factor 5-like
PGR progesterone receptor
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKD2L2 polycystic kidney disease 2-like 2
PLAC9 placenta-specific 9
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLVAP plasmalemma vesicle associated protein
POLB polymerase (DNA directed), beta
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
POU3F3 POU class 3 homeobox 3
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPT1 palmitoyl-protein thioesterase 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRND prion protein 2 (dublet)
PTCH2 patched 2
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
RAB3C RAB3C, member RAS oncogene family
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASL12 RAS-like, family 12
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM48 RNA binding motif protein 48
RCVRN recoverin
RELL2 RELT-like 2
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGPD8 RANBP2-like and GRIP domain containing 8
RGS12 regulator of G-protein signaling 12
RGS7BP regulator of G-protein signaling 7 binding protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL13AP17 ribosomal protein L13a pseudogene 17
RPSAP52 ribosomal protein SA pseudogene 52
SCD5 stearoyl-CoA desaturase 5
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN7A sodium channel, voltage gated, type VII alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCRT1 scratch family zinc finger 1
SDC2 syndecan 2
SEBOX SEBOX homeobox
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEPT7 septin 7
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFRP2 secreted frizzled-related protein 2
SFXN5 sideroflexin 5
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SGCE sarcoglycan, epsilon
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHOX2 short stature homeobox 2
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC22A17 solute carrier family 22, member 17
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC37A3 solute carrier family 37, member 3
SLC45A2 solute carrier family 45, member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD5-AS1 SMAD5 antisense RNA 1
SMOC2 SPARC related modular calcium binding 2
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNX10 sorting nexin 10
SOSTDC1 sclerostin domain containing 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPARCL1 SPARC-like 1 (hevin)
SPATA18 spermatogenesis associated 18
SPATA22 spermatogenesis associated 22
SPX spexin hormone
SRL sarcalumenin
SRRM3 serine/arginine repetitive matrix 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST7-AS2 ST7 antisense RNA 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP4 STEAP family member 4
STH saitohin
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUSD2 sushi domain containing 2
SVOP SV2 related protein homolog (rat)
TAGLN transgelin
TAS2R39 taste receptor, type 2, member 39
TAS2R42 taste receptor, type 2, member 42
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D28 TBC1 domain family, member 28
TBX2 T-box 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGDS TDP-glucose 4,6-dehydratase
TGFB3 transforming growth factor, beta 3
TLE2 transducin-like enhancer of split 2
TM4SF18 transmembrane 4 L six family member 18
TMEM168 transmembrane protein 168
TMEM207 transmembrane protein 207
TMEM26 transmembrane protein 26
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM1 tropomyosin 1 (alpha)
TSC22D4 TSC22 domain family, member 4
TSPO2 translocator protein 2
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBL3 ubiquitin-like 3
UNC5CL unc-5 homolog C (C. elegans)-like
USHBP1 Usher syndrome 1C binding protein 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
WBSCR22 Williams Beuren syndrome chromosome region 22
ZCWPW2 zinc finger, CW type with PWWP domain 2
ZFP36 ZFP36 ring finger protein
ZNF467 zinc finger protein 467
ZNF483 zinc finger protein 483
ZNF596 zinc finger protein 596

low expression

Symbol Name
TDP1 tyrosyl-DNA phosphodiesterase 1