Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z0-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

457 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z0-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTL7A actin-like 7A
ACVR2B activin A receptor, type IIB
ADGB androglobin
ADGRF5 adhesion G protein-coupled receptor F5
AFF2 AF4/FMR2 family, member 2
AGBL4 ATP/GTP binding protein-like 4
AGTPBP1 ATP/GTP binding protein 1
AKIRIN2 akirin 2
ALCAM activated leukocyte cell adhesion molecule
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ANKRD26 ankyrin repeat domain 26
ANKRD46 ankyrin repeat domain 46
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL10 ADP-ribosylation factor-like 10
ARL5B ADP-ribosylation factor-like 5B
ARMCX5 armadillo repeat containing, X-linked 5
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
ATAD5 ATPase family, AAA domain containing 5
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCLAF1 BCL2-associated transcription factor 1
BEND3 BEN domain containing 3
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BORA bora, aurora kinase A activator
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRD3 bromodomain containing 3
BRPF3 bromodomain and PHD finger containing, 3
BRWD3 bromodomain and WD repeat domain containing 3
C12ORF76 chromosome 12 open reading frame 76
C1ORF106 chromosome 1 open reading frame 106
C1ORF146 chromosome 1 open reading frame 146
C6ORF163 chromosome 6 open reading frame 163
C6ORF203 chromosome 6 open reading frame 203
C9ORF40 chromosome 9 open reading frame 40
C9ORF72 chromosome 9 open reading frame 72
CBX5 chromobox homolog 5
CCAR1 cell division cycle and apoptosis regulator 1
CCDC117 coiled-coil domain containing 117
CCDC28A coiled-coil domain containing 28A
CCNE2 cyclin E2
CCNJ cyclin J
CCP110 centriolar coiled coil protein 110kDa
CD5L CD5 molecule-like
CDC25C cell division cycle 25C
CDC5L cell division cycle 5-like
CDC7 cell division cycle 7
CDCA7 cell division cycle associated 7
CDK8 cyclin-dependent kinase 8
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CENPF centromere protein F, 350/400kDa
CENPJ centromere protein J
CENPK centromere protein K
CENPQ centromere protein Q
CEP192 centrosomal protein 192kDa
CEP76 centrosomal protein 76kDa
CEP78 centrosomal protein 78kDa
CHD7 chromodomain helicase DNA binding protein 7
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKAP2 cytoskeleton associated protein 2
CNOT10 CCR4-NOT transcription complex, subunit 10
CNOT6 CCR4-NOT transcription complex, subunit 6
CNTLN centlein, centrosomal protein
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
DCAF12 DDB1 and CUL4 associated factor 12
DCLRE1A DNA cross-link repair 1A
DCP2 decapping mRNA 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DEK DEK proto-oncogene
DGKH diacylglycerol kinase, eta
DHFR dihydrofolate reductase
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DICER1 dicer 1, ribonuclease type III
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLG5 discs, large homolog 5 (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMP1 dentin matrix acidic phosphoprotein 1
DNA2 DNA replication helicase/nuclease 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DOK5 docking protein 5
DOK6 docking protein 6
DPY19L4 dpy-19-like 4 (C. elegans)
DUSP27 dual specificity phosphatase 27 (putative)
DYM dymeclin
E2F3 E2F transcription factor 3
E2F5 E2F transcription factor 5, p130-binding
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EDDM3B epididymal protein 3B
EDNRB endothelin receptor type B
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A1P9 eukaryotic translation elongation factor 1 alpha 1 pseudogene 9
EFHC2 EF-hand domain (C-terminal) containing 2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELF1 E74-like factor 1 (ets domain transcription factor)
ELOVL5 ELOVL fatty acid elongase 5
ERC2-IT1 ERC2 intronic transcript 1
ESD esterase D
EXOC2 exocyst complex component 2
EXOSC8 exosome component 8
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM135A family with sequence similarity 135, member A
FAM49A family with sequence similarity 49, member A
FAM49B family with sequence similarity 49, member B
FAM74A3 family with sequence similarity 74, member A3
FAM92A1 family with sequence similarity 92, member A1
FGFBP3 fibroblast growth factor binding protein 3
FMR1 fragile X mental retardation 1
FOXP4 forkhead box P4
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GDAP1 ganglioside induced differentiation associated protein 1
GLO1 glyoxalase I
GMNN geminin, DNA replication inhibitor
GMPS guanine monphosphate synthase
GOPC golgi-associated PDZ and coiled-coil motif containing
GPALPP1 GPALPP motifs containing 1
GPR180 G protein-coupled receptor 180
GPR20 G protein-coupled receptor 20
GRIP2 glutamate receptor interacting protein 2
GRM6 glutamate receptor, metabotropic 6
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GTPBP8 GTP-binding protein 8 (putative)
HAUS1 HAUS augmin-like complex, subunit 1
HDDC2 HD domain containing 2
HELLS helicase, lymphoid-specific
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HIST1H2AC histone cluster 1, H2ac
HIST1H2AH histone cluster 1, H2ah
HIST1H2AK histone cluster 1, H2ak
HIST1H2BE histone cluster 1, H2be
HIST1H2BK histone cluster 1, H2bk
HIST1H2BN histone cluster 1, H2bn
HIST1H3F histone cluster 1, H3f
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGN1 high mobility group nucleosome binding domain 1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXB9 homeobox B9
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPH1 heat shock 105kDa/110kDa protein 1
IBSP integrin-binding sialoprotein
IFT74 intraflagellar transport 74
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL3 interleukin 3
INSC inscuteable homolog (Drosophila)
INTS8 integrator complex subunit 8
IPO11 importin 11
IPO5 importin 5
IQCB1 IQ motif containing B1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNRG potassium channel regulator
KDM6A lysine (K)-specific demethylase 6A
KIAA1586 KIAA1586
KIF11 kinesin family member 11
KIF20A kinesin family member 20A
KIF24 kinesin family member 24
KIF27 kinesin family member 27
KIF2A kinesin heavy chain member 2A
KLF12 Kruppel-like factor 12
KLHDC3 kelch domain containing 3
KLHL24 kelch-like family member 24
KLHL29 kelch-like family member 29
KLHL32 kelch-like family member 32
KLHL9 kelch-like family member 9
KNTC1 kinetochore associated 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LBR lamin B receptor
LCOR ligand dependent nuclear receptor corepressor
LIN28A lin-28 homolog A (C. elegans)
LIN28B lin-28 homolog B (C. elegans)
LMNB1 lamin B1
LOC100130691 uncharacterized LOC100130691
LOC221122 uncharacterized LOC221122
LOC441666 zinc finger protein 91 pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LPAR6 lysophosphatidic acid receptor 6
LRRC10B leucine rich repeat containing 10B
LRRC6 leucine rich repeat containing 6
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MAB21L2 mab-21-like 2 (C. elegans)
MAMDC2 MAM domain containing 2
MAML2 mastermind-like 2 (Drosophila)
MARCH5 membrane-associated ring finger (C3HC4) 5
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM9 minichromosome maintenance complex component 9
MEF2C myocyte enhancer factor 2C
MEOX2 mesenchyme homeobox 2
MEPE matrix extracellular phosphoglycoprotein
MEX3A mex-3 RNA binding family member A
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIMT1 MER1 repeat containing imprinted transcript 1 (non-protein coding)
MIS18BP1 MIS18 binding protein 1
MMS22L MMS22-like, DNA repair protein
MPHOSPH8 M-phase phosphoprotein 8
MRGPRG-AS1 MRGPRG antisense RNA 1
MRGPRX1 MAS-related GPR, member X1
MRPL18 mitochondrial ribosomal protein L18
MRPS31 mitochondrial ribosomal protein S31
MRS2 MRS2 magnesium transporter
MSGN1 mesogenin 1
MSH2 mutS homolog 2
MSI1 musashi RNA-binding protein 1
MTAP methylthioadenosine phosphorylase
MTBP MDM2 binding protein
MTMR8 myotubularin related protein 8
MTO1 mitochondrial tRNA translation optimization 1
MVB12B multivesicular body subunit 12B
MYO3A myosin IIIA
MYOZ1 myozenin 1
MYOZ3 myozenin 3
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative)
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDC80 NDC80 kinetochore complex component
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NEK3 NIMA-related kinase 3
NFYA nuclear transcription factor Y, alpha
NONO non-POU domain containing, octamer-binding
NPPB natriuretic peptide B
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUDCD1 NudC domain containing 1
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP153 nucleoporin 153kDa
NUPL1 nucleoporin like 1
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR6W1P olfactory receptor, family 6, subfamily W, member 1 pseudogene
ORC3 origin recognition complex, subunit 3
OSBPL11 oxysterol binding protein-like 11
OTUD6B OTU domain containing 6B
PALD1 phosphatase domain containing, paladin 1
PAMR1 peptidase domain containing associated with muscle regeneration 1
PBX2 pre-B-cell leukemia homeobox 2
PCDHA13 protocadherin alpha 13
PCDHAC2 protocadherin alpha subfamily C, 2
PCDHGA3 protocadherin gamma subfamily A, 3
PCGF6 polycomb group ring finger 6
PDCD2 programmed cell death 2
PDCL phosducin-like
PDS5B PDS5 cohesin associated factor B
PEG3 paternally expressed 3
PHF6 PHD finger protein 6
PIBF1 progesterone immunomodulatory binding factor 1
PLAG1 pleiomorphic adenoma gene 1
PLCB4 phospholipase C, beta 4
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLS3 plastin 3
POLE polymerase (DNA directed), epsilon, catalytic subunit
POU1F1 POU class 1 homeobox 1
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROSER1 proline and serine rich 1
PRPF4B pre-mRNA processing factor 4B
PRTFDC1 phosphoribosyl transferase domain containing 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSPC1 paraspeckle component 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAD50 RAD50 homolog (S. cerevisiae)
RANBP6 RAN binding protein 6
RAP2A RAP2A, member of RAS oncogene family
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RB1CC1 RB1-inducible coiled-coil 1
RBL1 retinoblastoma-like 1
RBM12 RNA binding motif protein 12
RBM12B RNA binding motif protein 12B
RBMS3 RNA binding motif, single stranded interacting protein 3
RCAN2 regulator of calcineurin 2
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RFXAP regulatory factor X-associated protein
RIC1 RAB6A GEF complex partner 1
RMI1 RecQ mediated genome instability 1
RNASEH2B ribonuclease H2, subunit B
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF138P1 ring finger protein 138, E3 ubiquitin protein ligase pseudogene 1
RNF146 ring finger protein 146
RNF219 ring finger protein 219
RPL29P2 ribosomal protein L29 pseudogene 2
RPL7L1 ribosomal protein L7-like 1
RRM1 ribonucleotide reductase M1
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTKN2 rhotekin 2
RTP1 receptor (chemosensory) transporter protein 1
RWDD1 RWD domain containing 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDHAF4 succinate dehydrogenase complex assembly factor 4
SET SET nuclear proto-oncogene
SKA3 spindle and kinetochore associated complex subunit 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC38A9 solute carrier family 38, member 9
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLFN12 schlafen family member 12
SLITRK6 SLIT and NTRK-like family, member 6
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMIM8 small integral membrane protein 8
SNX14 sorting nexin 14
SOX11 SRY (sex determining region Y)-box 11
SPIN1 spindlin 1
SQLE squalene epoxidase
SRPK1 SRSF protein kinase 1
STAG1 stromal antigen 1
STAG2 stromal antigen 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
STAU2 staufen double-stranded RNA binding protein 2
STRBP spermatid perinuclear RNA binding protein
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TADA2A transcriptional adaptor 2A
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAS2R30 taste receptor, type 2, member 30
TBC1D31 TBC1 domain family, member 31
TBP TATA box binding protein
TBPL1 TBP-like 1
TCAF1 TRPM8 channel-associated factor 1
TCP1 t-complex 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TEAD2 TEA domain family member 2
TEX10 testis expressed 10
TFAM transcription factor A, mitochondrial
TFDP1 transcription factor Dp-1
TGFBR1 transforming growth factor, beta receptor 1
TLE4 transducin-like enhancer of split 4
TMEM139 transmembrane protein 139
TMEM170B transmembrane protein 170B
TMPO thymopoietin
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TMX4 thioredoxin-related transmembrane protein 4
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOP2B topoisomerase (DNA) II beta 180kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TPR translocated promoter region, nuclear basket protein
TREH trehalase (brush-border membrane glycoprotein)
TRHR thyrotropin-releasing hormone receptor
TRIM13 tripartite motif containing 13
TXLNG taxilin gamma
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN7 UBX domain protein 7
UFL1 UFM1-specific ligase 1
UHRF1BP1 UHRF1 binding protein 1
UNC5C unc-5 homolog C (C. elegans)
USP49 ubiquitin specific peptidase 49
USPL1 ubiquitin specific peptidase like 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR48 WD repeat domain 48
WTAP Wilms tumor 1 associated protein
WWTR1 WW domain containing transcription regulator 1
XIST X inactive specific transcript (non-protein coding)
XPO4 exportin 4
XPO5 exportin 5
YOD1 YOD1 deubiquitinase
YTHDC2 YTH domain containing 2
ZBED6CL ZBED6 C-terminal like
ZBTB24 zinc finger and BTB domain containing 24
ZBTB26 zinc finger and BTB domain containing 26
ZC3H13 zinc finger CCCH-type containing 13
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZC4H2 zinc finger, C4H2 domain containing
ZDHHC20 zinc finger, DHHC-type containing 20
ZFP2 ZFP2 zinc finger protein
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZIC1 Zic family member 1
ZIM2 zinc finger, imprinted 2
ZKSCAN7 zinc finger with KRAB and SCAN domains 7
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF124 zinc finger protein 124
ZNF135 zinc finger protein 135
ZNF154 zinc finger protein 154
ZNF184 zinc finger protein 184
ZNF197 zinc finger protein 197
ZNF236 zinc finger protein 236
ZNF24 zinc finger protein 24
ZNF253 zinc finger protein 253
ZNF281 zinc finger protein 281
ZNF292 zinc finger protein 292
ZNF318 zinc finger protein 318
ZNF322 zinc finger protein 322
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF354C zinc finger protein 354C
ZNF391 zinc finger protein 391
ZNF445 zinc finger protein 445
ZNF451 zinc finger protein 451
ZNF454 zinc finger protein 454
ZNF486 zinc finger protein 486
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551
ZNF566 zinc finger protein 566
ZNF608 zinc finger protein 608
ZNF618 zinc finger protein 618
ZNF624 zinc finger protein 624
ZNF625 zinc finger protein 625
ZNF626 zinc finger protein 626
ZNF658 zinc finger protein 658
ZNF660 zinc finger protein 660
ZNF665 zinc finger protein 665
ZNF667 zinc finger protein 667
ZNF678 zinc finger protein 678
ZNF681 zinc finger protein 681
ZNF711 zinc finger protein 711
ZNF718 zinc finger protein 718
ZNF737 zinc finger protein 737
ZNF770 zinc finger protein 770
ZNF813 zinc finger protein 813
ZNF835 zinc finger protein 835
ZUFSP zinc finger with UFM1-specific peptidase domain