Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

345 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADAMDEC1 ADAM-like, decysin 1
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADGRG7 adhesion G protein-coupled receptor G7
ADPGK ADP-dependent glucokinase
AGTPBP1 ATP/GTP binding protein 1
AK2 adenylate kinase 2
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKRD22 ankyrin repeat domain 22
AOAH acyloxyacyl hydrolase (neutrophil)
APOL3 apolipoprotein L, 3
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AQP9 aquaporin 9
AQR aquarius intron-binding spliceosomal factor
ARF4 ADP-ribosylation factor 4
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ATXN7 ataxin 7
B2M beta-2-microglobulin
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2A1 BCL2-related protein A1
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
BTNL2 butyrophilin-like 2
C10ORF128 chromosome 10 open reading frame 128
C15ORF53 chromosome 15 open reading frame 53
C15ORF57 chromosome 15 open reading frame 57
C1ORF110 chromosome 1 open reading frame 110
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C2ORF49 chromosome 2 open reading frame 49
C2ORF71 chromosome 2 open reading frame 71
C3AR1 complement component 3a receptor 1
C4ORF50 chromosome 4 open reading frame 50
C9ORF139 chromosome 9 open reading frame 139
C9ORF85 chromosome 9 open reading frame 85
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CATSPER2 cation channel, sperm associated 2
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CCL1 chemokine (C-C motif) ligand 1
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCL8 chemokine (C-C motif) ligand 8
CCNDBP1 cyclin D-type binding-protein 1
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CCSAP centriole, cilia and spindle-associated protein
CD160 CD160 molecule
CD163 CD163 molecule
CD200R1 CD200 receptor 1
CD200R1L CD200 receptor 1-like
CD300LF CD300 molecule-like family member f
CD302 CD302 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC14C cell division cycle 14C
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CIAO1 cytosolic iron-sulfur assembly component 1
CIITA class II, major histocompatibility complex, transactivator
CLEC10A C-type lectin domain family 10, member A
CLEC12A C-type lectin domain family 12, member A
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand
CNGA4 cyclic nucleotide gated channel alpha 4
COL6A5 collagen, type VI, alpha 5
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CP ceruloplasmin (ferroxidase)
CPVL carboxypeptidase, vitellogenic-like
CRTAM cytotoxic and regulatory T cell molecule
CTAGE6 CTAGE family, member 6
CTSC cathepsin C
CTSS cathepsin S
CTSW cathepsin W
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR6 chemokine (C-X-C motif) receptor 6
CYBB cytochrome b-245, beta polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene)
DMXL2 Dmx-like 2
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DRAM1 DNA-damage regulated autophagy modulator 1
DTHD1 death domain containing 1
DUSP9 dual specificity phosphatase 9
EEA1 early endosome antigen 1
EIF4E3 eukaryotic translation initiation factor 4E family member 3
EMC4 ER membrane protein complex subunit 4
FAM179A family with sequence similarity 179, member A
FAM26F family with sequence similarity 26, member F
FAM81A family with sequence similarity 81, member A
FAM96A family with sequence similarity 96, member A
FASLG Fas ligand (TNF superfamily, member 6)
FBXO6 F-box protein 6
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL6 Fc receptor-like 6
FES FES proto-oncogene, tyrosine kinase
GALK2 galactokinase 2
GALM galactose mutarotase (aldose 1-epimerase)
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GCH1 GTP cyclohydrolase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GHSR growth hormone secretagogue receptor
GIMAP4 GTPase, IMAP family member 4
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GLCE glucuronic acid epimerase
GLUL glutamate-ammonia ligase
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GOLGA2 golgin A2
GPR155 G protein-coupled receptor 155
GPR171 G protein-coupled receptor 171
GPR174 G protein-coupled receptor 174
GPR89B G protein-coupled receptor 89B
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
H1FOO H1 histone family, member O, oocyte-specific
HABP4 hyaluronan binding protein 4
HAPLN3 hyaluronan and proteoglycan link protein 3
HAUS2 HAUS augmin-like complex, subunit 2
HAVCR1 hepatitis A virus cellular receptor 1
HCP5 HLA complex P5 (non-protein coding)
HEATR9 HEAT repeat containing 9
HIST1H4K histone cluster 1, H4k
HK3 hexokinase 3 (white cell)
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HMGB3P1 high mobility group box 3 pseudogene 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTRA4 HtrA serine peptidase 4
IFNA21 interferon, alpha 21
IFNG interferon, gamma
IFNL2 interferon, lambda 2
IGSF22 immunoglobulin superfamily, member 22
IGSF6 immunoglobulin superfamily, member 6
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL15RA interleukin 15 receptor, alpha
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL21 interleukin 21
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL33 interleukin 33
IL4I1 interleukin 4 induced 1
IQCH IQ motif containing H
IVNS1ABP influenza virus NS1A binding protein
JAKMIP1 janus kinase and microtubule interacting protein 1
KIF3C kinesin family member 3C
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAP3 leucine aminopeptidase 3
LDHAL6B lactate dehydrogenase A-like 6B
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LEPROTL1 leptin receptor overlapping transcript-like 1
LHFPL1 lipoma HMGIC fusion partner-like 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINGO4 leucine rich repeat and Ig domain containing 4
LINS lines homolog (Drosophila)
LOC100130872 uncharacterized LOC100130872
LOC441455 makorin ring finger protein 1 pseudogene
LOC645752 golgin A6 family, member A pseudogene
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC57 leucine rich repeat containing 57
LYZ lysozyme
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MCEE methylmalonyl CoA epimerase
MCOLN2 mucolipin 2
MEFV Mediterranean fever
MESDC2 mesoderm development candidate 2
MIAT myocardial infarction associated transcript (non-protein coding)
MKRN3 makorin ring finger protein 3
MORF4L1 mortality factor 4 like 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MRC1 mannose receptor, C type 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYCNOS MYCN opposite strand
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAIP NLR family, apoptosis inhibitory protein
NCF1B neutrophil cytosolic factor 1B pseudogene
NEUROG3 neurogenin 3
NFAM1 NFAT activating protein with ITAM motif 1
NHLRC3 NHL repeat containing 3
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NLRC3 NLR family, CARD domain containing 3
NMRK1 nicotinamide riboside kinase 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2A7 olfactory receptor, family 2, subfamily A, member 7
OR51A4 olfactory receptor, family 51, subfamily A, member 4
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PATL2 protein associated with topoisomerase II homolog 2 (yeast)
PCDHGA3 protocadherin gamma subfamily A, 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHF5A PHD finger protein 5A
PIAS1 protein inhibitor of activated STAT, 1
PLA2G2D phospholipase A2, group IID
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEK pleckstrin
PMM1 phosphomannomutase 1
PNPLA3 patatin-like phospholipase domain containing 3
PPP1R21 protein phosphatase 1, regulatory subunit 21
PRF1 perforin 1 (pore forming protein)
PRR5L proline rich 5 like
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTAFR platelet-activating factor receptor
PTCH1 patched 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYHIN1 pyrin and HIN domain family, member 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB27A RAB27A, member RAS oncogene family
RAD21L1 RAD21-like 1 (S. pombe)
RALGDS ral guanine nucleotide dissociation stimulator
RAP1GAP RAP1 GTPase activating protein
RASD2 RASD family, member 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBMXL3 RNA binding motif protein, X-linked-like 3
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RMDN3 regulator of microtubule dynamics 3
RNF111 ring finger protein 111
RNF114 ring finger protein 114
RNF213 ring finger protein 213
RORC RAR-related orphan receptor C
RSPO3 R-spondin 3
SAMD3 sterile alpha motif domain containing 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCIMP SLP adaptor and CSK interacting membrane protein
SCPEP1 serine carboxypeptidase 1
SEPT3 septin 3
SERHL serine hydrolase-like (pseudogene)
SFTA1P surfactant associated 1, pseudogene
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIRPB1 signal-regulatory protein beta 1
SIRPD signal-regulatory protein delta
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A15 solute carrier family 22, member 15
SLC46A3 solute carrier family 46, member 3
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLFN12L schlafen family member 12-like
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAP23 synaptosomal-associated protein, 23kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNORA45B small nucleolar RNA, H/ACA box 45B
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SOD2 superoxide dismutase 2, mitochondrial
SPG11 spastic paraplegia 11 (autosomal recessive)
SQRDL sulfide quinone reductase-like (yeast)
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
STAT1 signal transducer and activator of transcription 1, 91kDa
STRIP2 striatin interacting protein 2
STX11 syntaxin 11
STYK1 serine/threonine/tyrosine kinase 1
SUMO1P1 SUMO1 pseudogene 1
SUSD3 sushi domain containing 3
TARP TCR gamma alternate reading frame protein
TBC1D29 TBC1 domain family, member 29
TBC1D2B TBC1 domain family, member 2B
TEF thyrotrophic embryonic factor
TFEC transcription factor EC
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TLR8 toll-like receptor 8
TM6SF1 transmembrane 6 superfamily member 1
TMEM150B transmembrane protein 150B
TMEM176B transmembrane protein 176B
TMEM237 transmembrane protein 237
TMEM62 transmembrane protein 62
TMEM63C transmembrane protein 63C
TMF1 TATA element modulatory factor 1
TMIGD1 transmembrane and immunoglobulin domain containing 1
TMPRSS3 transmembrane protease, serine 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNIP3 TNFAIP3 interacting protein 3
TPD52L1 tumor protein D52-like 1
TREML4 triggering receptor expressed on myeloid cells-like 4
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TYW5 tRNA-yW synthesizing protein 5
UBASH3A ubiquitin associated and SH3 domain containing A
UBD ubiquitin D
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBXN10 UBX domain protein 10
UNC50 unc-50 homolog (C. elegans)
VAMP5 vesicle-associated membrane protein 5
VANGL1 VANGL planar cell polarity protein 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
WBP2NL WBP2 N-terminal like
XCL2 chemokine (C motif) ligand 2
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFAND6 zinc finger, AN1-type domain 6
ZNF683 zinc finger protein 683
ZNFX1 zinc finger, NFX1-type containing 1