Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

422 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACRBP acrosin binding protein
ADAP2 ArfGAP with dual PH domains 2
ADGRB1 adhesion G protein-coupled receptor B1
AGA aspartylglucosaminidase
AIF1 allograft inflammatory factor 1
AIG1 androgen-induced 1
AKAP5 A kinase (PRKA) anchor protein 5
ALOX15 arachidonate 15-lipoxygenase
ANKRD22 ankyrin repeat domain 22
AOAH acyloxyacyl hydrolase (neutrophil)
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOL1 apolipoprotein L, 1
APOL3 apolipoprotein L, 3
APOL4 apolipoprotein L, 4
ARHGAP6 Rho GTPase activating protein 6
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG5 BCL2-associated athanogene 5
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCAS2 breast carcinoma amplified sequence 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BEND6 BEN domain containing 6
BMX BMX non-receptor tyrosine kinase
BPIFB2 BPI fold containing family B, member 2
BTNL3 butyrophilin-like 3
C10ORF128 chromosome 10 open reading frame 128
C11ORF94 chromosome 11 open reading frame 94
C14ORF159 chromosome 14 open reading frame 159
C15ORF53 chromosome 15 open reading frame 53
C16ORF89 chromosome 16 open reading frame 89
C17ORF47 chromosome 17 open reading frame 47
C17ORF67 chromosome 17 open reading frame 67
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4A complement component 4A (Rodgers blood group)
C4BPB complement component 4 binding protein, beta
C5ORF15 chromosome 5 open reading frame 15
C6ORF223 chromosome 6 open reading frame 223
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CAT catalase
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBWD3 COBW domain containing 3
CCDC37 coiled-coil domain containing 37
CCDC50 coiled-coil domain containing 50
CCDC79 coiled-coil domain containing 79
CCL4 chemokine (C-C motif) ligand 4
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL5 chemokine (C-C motif) ligand 5
CCNI2 cyclin I family, member 2
CCNYL1 cyclin Y-like 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CD101 CD101 molecule
CD226 CD226 molecule
CD38 CD38 molecule
CD72 CD72 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CIB3 calcium and integrin binding family member 3
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLSTN3 calsyntenin 3
CMTM5 CKLF-like MARVEL transmembrane domain containing 5
CNPY2 canopy FGF signaling regulator 2
COTL1 coactosin-like F-actin binding protein 1
COX20 COX20 cytochrome c oxidase assembly factor
CRELD1 cysteine-rich with EGF-like domains 1
CRELD2 cysteine-rich with EGF-like domains 2
CRTAM cytotoxic and regulatory T cell molecule
CSDE1 cold shock domain containing E1, RNA-binding
CSNK1G3 casein kinase 1, gamma 3
CSRP1 cysteine and glycine-rich protein 1
CTHRC1 collagen triple helix repeat containing 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSC cathepsin C
CTSW cathepsin W
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
CXXC5 CXXC finger protein 5
CYB561D1 cytochrome b561 family, member D1
DAO D-amino-acid oxidase
DCLRE1B DNA cross-link repair 1B
DDO D-aspartate oxidase
DENND1B DENN/MADD domain containing 1B
DENND2C DENN/MADD domain containing 2C
DGCR10 DiGeorge syndrome critical region gene 10 (non-protein coding)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18
DPYS dihydropyrimidinase
DRAM1 DNA-damage regulated autophagy modulator 1
DRD5 dopamine receptor D5
DSCR4 Down syndrome critical region 4
DSCR8 Down syndrome critical region 8
DUSP6 dual specificity phosphatase 6
DYNAP dynactin associated protein
DYNLT1 dynein, light chain, Tctex-type 1
DYSF dysferlin
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAC1 elaC ribonuclease Z 1
ELMO1 engulfment and cell motility 1
ELOVL2 ELOVL fatty acid elongase 2
EMILIN1 elastin microfibril interfacer 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPSTI1 epithelial stromal interaction 1 (breast)
ERAP2 endoplasmic reticulum aminopeptidase 2
ERICH6 glutamate-rich 6
ETV4 ets variant 4
EWSAT1 Ewing sarcoma associated transcript 1
EXT2 exostosin glycosyltransferase 2
FADS2 fatty acid desaturase 2
FAM26F family with sequence similarity 26, member F
FAM66A family with sequence similarity 66, member A
FATE1 fetal and adult testis expressed 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCRL6 Fc receptor-like 6
FGF13 fibroblast growth factor 13
FICD FIC domain containing
FLJ36777 uncharacterized LOC730971
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FMO9P flavin containing monooxygenase 9 pseudogene
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FSCB fibrous sheath CABYR binding protein
GAL3ST2 galactose-3-O-sulfotransferase 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GALC galactosylceramidase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP5 guanylate binding protein 5
GCH1 GTP cyclohydrolase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP1 ganglioside induced differentiation associated protein 1
GFI1 growth factor independent 1 transcription repressor
GFI1B growth factor independent 1B transcription repressor
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GIMAP8 GTPase, IMAP family member 8
GINM1 glycoprotein integral membrane 1
GJD3 gap junction protein, delta 3, 31.9kDa
GKAP1 G kinase anchoring protein 1
GLT6D1 glycosyltransferase 6 domain containing 1
GOLM1 golgi membrane protein 1
GPBAR1 G protein-coupled bile acid receptor 1
GPR119 G protein-coupled receptor 119
GPR152 G protein-coupled receptor 152
GPR171 G protein-coupled receptor 171
GPR65 G protein-coupled receptor 65
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GTSF1L gametocyte specific factor 1-like
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR2 hepatitis A virus cellular receptor 2
HIPK1 homeodomain interacting protein kinase 1
HK3 hexokinase 3 (white cell)
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HRCT1 histidine rich carboxyl terminus 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HYAL2 hyaluronoglucosaminidase 2
ICA1L islet cell autoantigen 1,69kDa-like
ICOS inducible T-cell co-stimulator
IDNK idnK, gluconokinase homolog (E. coli)
IFI35 interferon-induced protein 35
IFNA21 interferon, alpha 21
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL15RA interleukin 15 receptor, alpha
IL18BP interleukin 18 binding protein
IL18RAP interleukin 18 receptor accessory protein
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IPCEF1 interaction protein for cytohesin exchange factors 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
IZUMO1R IZUMO1 receptor, JUNO
JAKMIP1 janus kinase and microtubule interacting protein 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCTD12 potassium channel tetramerization domain containing 12
KIF5C kinesin family member 5C
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL36 kelch-like family member 36
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT36 keratin 36, type I
KRT8 keratin 8, type II
LAG3 lymphocyte-activation gene 3
LAMA4 laminin, alpha 4
LASP1 LIM and SH3 protein 1
LBX2 ladybird homeobox 2
LEMD1 LEM domain containing 1
LGMN legumain
LGSN lengsin, lens protein with glutamine synthetase domain
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00092 long intergenic non-protein coding RNA 92
LINC00271 long intergenic non-protein coding RNA 271
LINC00467 long intergenic non-protein coding RNA 467
LINC01587 long intergenic non-protein coding RNA 1587
LOC100272216 uncharacterized LOC100272216
LOC153684 uncharacterized LOC153684
LOC541473 FK506 binding protein 6, 36kDa pseudogene
LOC641367 cyclin Y-like 1 pseudogene
LOC729609 uncharacterized LOC729609
LOC81691 exonuclease NEF-sp
LPXN leupaxin
LRRC25 leucine rich repeat containing 25
LRRK2 leucine-rich repeat kinase 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAGT1 magnesium transporter 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MARVELD3 MARVEL domain containing 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEFV Mediterranean fever
METTL7B methyltransferase like 7B
MFAP3 microfibrillar-associated protein 3
MLEC malectin
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPZ myelin protein zero
MR1 major histocompatibility complex, class I-related
MROH8 maestro heat-like repeat family member 8
MRPS6 mitochondrial ribosomal protein S6
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSI1 musashi RNA-binding protein 1
MST1 macrophage stimulating 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYCBPAP MYCBP associated protein
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYO1F myosin IF
MYO5C myosin VC
MYO7A myosin VIIA
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NCR1 natural cytotoxicity triggering receptor 1
NEBL nebulette
NEUROG3 neurogenin 3
NFE2 nuclear factor, erythroid 2
NKG7 natural killer cell granule protein 7
NLRC4 NLR family, CARD domain containing 4
NPC2 Niemann-Pick disease, type C2
NRAP nebulin-related anchoring protein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5DC3 5'-nucleotidase domain containing 3
NUCB2 nucleobindin 2
OLFML3 olfactomedin-like 3
OOSP2 oocyte secreted protein 2
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR2M3 olfactory receptor, family 2, subfamily M, member 3
OR4K5 olfactory receptor, family 4, subfamily K, member 5
OR5B2 olfactory receptor, family 5, subfamily B, member 2
OR9I1 olfactory receptor, family 9, subfamily I, member 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHGB7 protocadherin gamma subfamily B, 7
PDCD1 programmed cell death 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA3 protein disulfide isomerase family A, member 3
PDIA3P1 protein disulfide isomerase family A, member 3 pseudogene 1
PDIA4 protein disulfide isomerase family A, member 4
PDIA6 protein disulfide isomerase family A, member 6
PELI1 pellino E3 ubiquitin protein ligase 1
PEX5L peroxisomal biogenesis factor 5-like
PHACTR2 phosphatase and actin regulator 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PHTF1 putative homeodomain transcription factor 1
PISRT1 polled intersex syndrome regulated transcript 1 (non-protein coding RNA)
PLA1A phospholipase A1 member A
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRAC2 prostate cancer susceptibility candidate 2
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
PRLH prolactin releasing hormone
PRR34 proline rich 34
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM22 RNA binding motif protein 22
RBP5 retinol binding protein 5, cellular
RGPD1 RANBP2-like and GRIP domain containing 1
RHOC ras homolog family member C
RLBP1 retinaldehyde binding protein 1
RNASE13 ribonuclease, RNase A family, 13 (non-active)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RNASET2 ribonuclease T2
RXFP4 relaxin/insulin-like family peptide receptor 4
SAMD3 sterile alpha motif domain containing 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SDSL serine dehydratase-like
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHROOM2 shroom family member 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC7 sialic acid binding Ig-like lectin 7
SIKE1 suppressor of IKBKE 1
SIRPD signal-regulatory protein delta
SIRPG signal-regulatory protein gamma
SIX1 SIX homeobox 1
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLAMF8 SLAM family member 8
SLC25A35 solute carrier family 25, member 35
SLC25A45 solute carrier family 25, member 45
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLFN11 schlafen family member 11
SMAD5 SMAD family member 5
SMAD5-AS1 SMAD5 antisense RNA 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA67 small nucleolar RNA, H/ACA box 67
SOCS1 suppressor of cytokine signaling 1
SPAG4 sperm associated antigen 4
SPTB spectrin, beta, erythrocytic
SQRDL sulfide quinone reductase-like (yeast)
STAT1 signal transducer and activator of transcription 1, 91kDa
STX11 syntaxin 11
STYK1 serine/threonine/tyrosine kinase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SUMO1P1 SUMO1 pseudogene 1
SUSD6 sushi domain containing 6
SYCE3 synaptonemal complex central element protein 3
SYNPO synaptopodin
SYT6 synaptotagmin VI
TAPBP TAP binding protein (tapasin)
TAPBPL TAP binding protein-like
TBC1D28 TBC1 domain family, member 28
TBX21 T-box 21
TEX38 testis expressed 38
TGFB3 transforming growth factor, beta 3
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TMEM107 transmembrane protein 107
TMEM132A transmembrane protein 132A
TMEM150B transmembrane protein 150B
TMEM170A transmembrane protein 170A
TMEM30A transmembrane protein 30A
TMEM30B transmembrane protein 30B
TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene
TMSB4XP8 thymosin beta 4, X-linked pseudogene 8
TMSB4Y thymosin beta 4, Y-linked
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP3 TNFAIP3 interacting protein 3
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TOX3 TOX high mobility group box family member 3
TP53I3 tumor protein p53 inducible protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM33 tripartite motif containing 33
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSPYL2 TSPY-like 2
TTC24 tetratricopeptide repeat domain 24
TTLL6 tubulin tyrosine ligase-like family member 6
TTTY18 testis-specific transcript, Y-linked 18 (non-protein coding)
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
ULBP3 UL16 binding protein 3
USH1C Usher syndrome 1C (autosomal recessive, severe)
VMO1 vitelline membrane outer layer 1 homolog (chicken)
VSTM5 V-set and transmembrane domain containing 5
WARS tryptophanyl-tRNA synthetase
XIRP1 xin actin binding repeat containing 1
ZBED2 zinc finger, BED-type containing 2
ZDHHC2 zinc finger, DHHC-type containing 2
ZDHHC23 zinc finger, DHHC-type containing 23
ZMYND15 zinc finger, MYND-type containing 15
ZNF596 zinc finger protein 596
ZNF683 zinc finger protein 683
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZPBP zona pellucida binding protein