Skin Cutaneous Melanoma_SKCM_TCGA-ER-A198-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

226 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-ER-A198-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAT2 acetyl-CoA acetyltransferase 2
ACER2 alkaline ceramidase 2
ACLY ATP citrate lyase
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTRT1 actin-related protein T1
ANKRD36B ankyrin repeat domain 36B
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGAP29 Rho GTPase activating protein 29
ATAD2 ATPase family, AAA domain containing 2
ATM ATM serine/threonine kinase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD10 BTB (POZ) domain containing 10
C14ORF1 chromosome 14 open reading frame 1
C19ORF71 chromosome 19 open reading frame 71
C9ORF91 chromosome 9 open reading frame 91
CACUL1 CDK2-associated, cullin domain 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC15 coiled-coil domain containing 15
CCND1 cyclin D1
CCNG1 cyclin G1
CCSER2 coiled-coil serine-rich protein 2
CDC6 cell division cycle 6
CDCA2 cell division cycle associated 2
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPI centromere protein I
CENPN centromere protein N
CEP55 centrosomal protein 55kDa
CEP78 centrosomal protein 78kDa
CFAP46 cilia and flagella associated protein 46
CHEK1 checkpoint kinase 1
CISD1 CDGSH iron sulfur domain 1
CKAP2 cytoskeleton associated protein 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLDND2 claudin domain containing 2
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DENND4C DENN/MADD domain containing 4C
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DNA2 DNA replication helicase/nuclease 2
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DUSP4 dual specificity phosphatase 4
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
EPHA2 EPH receptor A2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC6L2 excision repair cross-complementation group 6-like 2
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
EXOC6 exocyst complex component 6
FAM102B family with sequence similarity 102, member B
FAM161A family with sequence similarity 161, member A
FAM171B family with sequence similarity 171, member B
FAM187B family with sequence similarity 187, member B
FAM188A family with sequence similarity 188, member A
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FANCD2 Fanconi anemia, complementation group D2
FAXC failed axon connections homolog (Drosophila)
FBXL4 F-box and leucine-rich repeat protein 4
FGFBP3 fibroblast growth factor binding protein 3
FRAS1 Fraser extracellular matrix complex subunit 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GFRAL GDNF family receptor alpha like
GINS2 GINS complex subunit 2 (Psf2 homolog)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMNN geminin, DNA replication inhibitor
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GSTCD glutathione S-transferase, C-terminal domain containing
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAUS6 HAUS augmin-like complex, subunit 6
HEATR3 HEAT repeat containing 3
HEATR5A HEAT repeat containing 5A
HELLS helicase, lymphoid-specific
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMGB3P1 high mobility group box 3 pseudogene 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HN1L hematological and neurological expressed 1-like
HSDL1 hydroxysteroid dehydrogenase like 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IFNGR1 interferon gamma receptor 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INSIG1 insulin induced gene 1
IPMK inositol polyphosphate multikinase
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNU1 potassium channel, subfamily U, member 1
KIAA0754 KIAA0754
KIF11 kinesin family member 11
KIF20B kinesin family member 20B
KIF24 kinesin family member 24
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLLN killin, p53-regulated DNA replication inhibitor
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LATS2 large tumor suppressor kinase 2
LDLR low density lipoprotein receptor
LHFPL1 lipoma HMGIC fusion partner-like 1
LINC00476 long intergenic non-protein coding RNA 476
LMBR1 limb development membrane protein 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPIN1 lipin 1
LRP4 low density lipoprotein receptor-related protein 4
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAEA macrophage erythroblast attacher
MALT1 MALT1 paracaspase
MASTL microtubule associated serine/threonine kinase-like
MAT1A methionine adenosyltransferase I, alpha
MELK maternal embryonic leucine zipper kinase
METTL9 methyltransferase like 9
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKI67 marker of proliferation Ki-67
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type
MPPED2 metallophosphoesterase domain containing 2
MRPL30 mitochondrial ribosomal protein L30
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E
MSMO1 methylsterol monooxygenase 1
MTFMT mitochondrial methionyl-tRNA formyltransferase
MTFR2 mitochondrial fission regulator 2
MVD mevalonate (diphospho) decarboxylase
MYH10 myosin, heavy chain 10, non-muscle
MYO1D myosin ID
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG non-SMC condensin I complex, subunit G
NCAPH non-SMC condensin I complex, subunit H
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NHLRC2 NHL repeat containing 2
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NPAT nuclear protein, ataxia-telangiectasia locus
NPM2 nucleophosmin/nucleoplasmin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OAT ornithine aminotransferase
OR14I1 olfactory receptor, family 14, subfamily I, member 1
ORC6 origin recognition complex, subunit 6
PANK3 pantothenate kinase 3
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCNA proliferating cell nuclear antigen
PDCL3 phosducin-like 3
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PELI2 pellino E3 ubiquitin protein ligase family member 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLK4 polo-like kinase 4
PLS1 plastin 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRKCB protein kinase C, beta
PRKD3 protein kinase D3
PRR11 proline rich 11
PRSS48 protease, serine, 48
PSAT1 phosphoserine aminotransferase 1
PSIP1 PC4 and SFRS1 interacting protein 1
PTCD3 pentatricopeptide repeat domain 3
PXK PX domain containing serine/threonine kinase
PXMP2 peroxisomal membrane protein 2, 22kDa
RASEF RAS and EF-hand domain containing
RASIP1 Ras interacting protein 1
RBL1 retinoblastoma-like 1
RMI2 RecQ mediated genome instability 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRM1 ribonucleotide reductase M1
RTKN2 rhotekin 2
RTN4RL1 reticulon 4 receptor-like 1
SAE1 SUMO1 activating enzyme subunit 1
SCML4 sex comb on midleg-like 4 (Drosophila)
SEPT10 septin 10
SESN1 sestrin 1
SETX senataxin
SH2D5 SH2 domain containing 5
SKA3 spindle and kinetochore associated complex subunit 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLFN5 schlafen family member 5
SNORA4 small nucleolar RNA, H/ACA box 4
SPA17 sperm autoantigenic protein 17
SRR serine racemase
STARD7 StAR-related lipid transfer (START) domain containing 7
STOX1 storkhead box 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYTL2 synaptotagmin-like 2
TDRD7 tudor domain containing 7
TEKT5 tektin 5
TFAM transcription factor A, mitochondrial
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMELESS timeless circadian clock
TMEM131 transmembrane protein 131
TMEM163 transmembrane protein 163
TMEM194A transmembrane protein 194A
TMEM97 transmembrane protein 97
TOP2A topoisomerase (DNA) II alpha 170kDa
TRPM6 transient receptor potential cation channel, subfamily M, member 6
UGCG UDP-glucose ceramide glucosyltransferase
UNC13B unc-13 homolog B (C. elegans)
USP53 ubiquitin specific peptidase 53
VEPH1 ventricular zone expressed PH domain-containing 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDPCP WD repeat containing planar cell polarity effector
WDR91 WD repeat domain 91
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZC3H13 zinc finger CCCH-type containing 13
ZNF367 zinc finger protein 367
ZNF432 zinc finger protein 432
ZNF616 zinc finger protein 616
ZNF841 zinc finger protein 841
ZWINT ZW10 interacting kinetochore protein

low expression

Symbol Name
C9ORF64 chromosome 9 open reading frame 64
ERCC3 excision repair cross-complementation group 3
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
SMIM15 small integral membrane protein 15
ZNF140 zinc finger protein 140
ZNF263 zinc finger protein 263
ZNF350 zinc finger protein 350