Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

418 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABI3BP ABI family, member 3 (NESH) binding protein
ACE angiotensin I converting enzyme
ACOXL acyl-CoA oxidase-like
ADAMDEC1 ADAM-like, decysin 1
ADGRG5 adhesion G protein-coupled receptor G5
ADORA2A adenosine A2a receptor
AIF1 allograft inflammatory factor 1
AKNA AT-hook transcription factor
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALPL alkaline phosphatase, liver/bone/kidney
AMICA1 adhesion molecule, interacts with CXADR antigen 1
AMOT angiomotin
AMPD1 adenosine monophosphate deaminase 1
AOAH acyloxyacyl hydrolase (neutrophil)
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGAP25 Rho GTPase activating protein 25
ARHGAP27 Rho GTPase activating protein 27
ARHGAP30 Rho GTPase activating protein 30
ARL11 ADP-ribosylation factor-like 11
ASB2 ankyrin repeat and SOCS box containing 2
ATF5 activating transcription factor 5
ATG7 autophagy related 7
BATF basic leucine zipper transcription factor, ATF-like
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BHLHA15 basic helix-loop-helix family, member a15
BIN2 bridging integrator 2
BMP10 bone morphogenetic protein 10
BTG2 BTG family, member 2
BTK Bruton agammaglobulinemia tyrosine kinase
C10ORF54 chromosome 10 open reading frame 54
C11ORF53 chromosome 11 open reading frame 53
C16ORF54 chromosome 16 open reading frame 54
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C3 complement component 3
C5AR2 complement component 5a receptor 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC69 coiled-coil domain containing 69
CCL1 chemokine (C-C motif) ligand 1
CCL25 chemokine (C-C motif) ligand 25
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR8 chemokine (C-C motif) receptor 8
CCRL2 chemokine (C-C motif) receptor-like 2
CD180 CD180 molecule
CD1B CD1b molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD300A CD300a molecule
CD300C CD300c molecule
CD300E CD300e molecule
CD300LB CD300 molecule-like family member b
CD300LF CD300 molecule-like family member f
CD38 CD38 molecule
CD4 CD4 molecule
CD5 CD5 molecule
CD53 CD53 molecule
CD6 CD6 molecule
CD68 CD68 molecule
CD7 CD7 molecule
CD80 CD80 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CDH23 cadherin-related 23
CDX1 caudal type homeobox 1
CEACAM22P carcinoembryonic antigen-related cell adhesion molecule 22, pseudogene
CECR1 cat eye syndrome chromosome region, candidate 1
CELA1 chymotrypsin-like elastase family, member 1
CFD complement factor D (adipsin)
CFP complement factor properdin
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC10A C-type lectin domain family 10, member A
CLEC12A C-type lectin domain family 12, member A
CLEC4C C-type lectin domain family 4, member C
CLEC4E C-type lectin domain family 4, member E
COL4A4 collagen, type IV, alpha 4
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COLEC12 collectin sub-family member 12
CPA5 carboxypeptidase A5
CPNE9 copine family member IX
CRB2 crumbs family member 2
CREG1 cellular repressor of E1A-stimulated genes 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CTSS cathepsin S
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR3 chemokine (C-X-C motif) receptor 3
CXORF21 chromosome X open reading frame 21
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYSLTR1 cysteinyl leukotriene receptor 1
CYTH1 cytohesin 1
CYTH4 cytohesin 4
CYTIP cytohesin 1 interacting protein
DAZL deleted in azoospermia-like
DCANP1 dendritic cell-associated nuclear protein
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DERL3 derlin 3
DGKG diacylglycerol kinase, gamma 90kDa
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DOCK2 dedicator of cytokinesis 2
DOK2 docking protein 2, 56kDa
EBI3 Epstein-Barr virus induced 3
EGF epidermal growth factor
EMILIN2 elastin microfibril interfacer 2
ERICH6 glutamate-rich 6
ERVFRD-1 endogenous retrovirus group FRD, member 1
FAM110A family with sequence similarity 110, member A
FAM167B family with sequence similarity 167, member B
FAM170B family with sequence similarity 170, member B
FAM179A family with sequence similarity 179, member A
FAM46C family with sequence similarity 46, member C
FAM78A family with sequence similarity 78, member A
FAM92B family with sequence similarity 92, member B
FBP1 fructose-1,6-bisphosphatase 1
FBXO40 F-box protein 40
FBXO47 F-box protein 47
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FCRL5 Fc receptor-like 5
FERMT3 fermitin family member 3
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FLJ41941 uncharacterized LOC100192420
FLT3 fms-related tyrosine kinase 3
FMO1 flavin containing monooxygenase 1
FMR1NB fragile X mental retardation 1 neighbor
FOLR2 folate receptor 2 (fetal)
FOXP3 forkhead box P3
FPR3 formyl peptide receptor 3
FTL ferritin, light polypeptide
FUCA1 fucosidase, alpha-L- 1, tissue
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
G6PD glucose-6-phosphate dehydrogenase
GAB3 GRB2-associated binding protein 3
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GIMAP1 GTPase, IMAP family member 1
GIMAP5 GTPase, IMAP family member 5
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GPBAR1 G protein-coupled bile acid receptor 1
GPR139 G protein-coupled receptor 139
GPR31 G protein-coupled receptor 31
GRB2 growth factor receptor-bound protein 2
GRIPAP1 GRIP1 associated protein 1
GUCY2EP guanylate cyclase 2E, pseudogene
H1FNT H1 histone family, member N, testis-specific
HAVCR2 hepatitis A virus cellular receptor 2
HCG22 HLA complex group 22
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCRT hypocretin (orexin) neuropeptide precursor
HCST hematopoietic cell signal transducer
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHEX hematopoietically expressed homeobox
HID1 HID1 domain containing
HIST1H3D histone cluster 1, H3d
HIST1H3H histone cluster 1, H3h
HIST2H2AA3 histone cluster 2, H2aa3
HIST2H2BE histone cluster 2, H2be
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMHA1 histocompatibility (minor) HA-1
HMHB1 histocompatibility (minor) HB-1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSH2D hematopoietic SH2 domain containing
HTRA4 HtrA serine peptidase 4
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICOS inducible T-cell co-stimulator
IFI30 interferon, gamma-inducible protein 30
IFI35 interferon-induced protein 35
IFNAR2 interferon (alpha, beta and omega) receptor 2
IGFLR1 IGF-like family receptor 1
IGSF6 immunoglobulin superfamily, member 6
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12RB1 interleukin 12 receptor, beta 1
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL18RAP interleukin 18 receptor accessory protein
IL1R1 interleukin 1 receptor, type I
IL27 interleukin 27
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4I1 interleukin 4 induced 1
INSL3 insulin-like 3 (Leydig cell)
INSL6 insulin-like 6
IRF2 interferon regulatory factor 2
IRF5 interferon regulatory factor 5
IRF9 interferon regulatory factor 9
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
JSRP1 junctional sarcoplasmic reticulum protein 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIF19 kinesin family member 19
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT20 keratin 20, type I
LAMP3 lysosomal-associated membrane protein 3
LAX1 lymphocyte transmembrane adaptor 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS2 lectin, galactoside-binding, soluble, 2
LGMN legumain
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LIME1 Lck interacting transmembrane adaptor 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC284379 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene
LRRC14B leucine rich repeat containing 14B
LRRC25 leucine rich repeat containing 25
LST1 leukocyte specific transcript 1
LY9 lymphocyte antigen 9
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MEI1 meiosis inhibitor 1
MIXL1 Mix paired-like homeobox
MLKL mixed lineage kinase domain-like
MMP19 matrix metallopeptidase 19
MMP25 matrix metallopeptidase 25
MPEG1 macrophage expressed 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MSN moesin
MTMR14 myotubularin related protein 14
MYO1F myosin IF
NAAA N-acylethanolamine acid amidase
NAGK N-acetylglucosamine kinase
NCF1 neutrophil cytosolic factor 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKAP1L NCK-associated protein 1-like
NECAP2 NECAP endocytosis associated 2
NFAM1 NFAT activating protein with ITAM motif 1
NLRC4 NLR family, CARD domain containing 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
ODF1 outer dense fiber of sperm tails 1
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)
OR2Z1 olfactory receptor, family 2, subfamily Z, member 1
OR51M1 olfactory receptor, family 51, subfamily M, member 1
OR52W1 olfactory receptor, family 52, subfamily W, member 1
OR5M11 olfactory receptor, family 5, subfamily M, member 11
OR5M8 olfactory receptor, family 5, subfamily M, member 8
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OSGIN1 oxidative stress induced growth inhibitor 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP14 poly (ADP-ribose) polymerase family, member 14
PCCB propionyl CoA carboxylase, beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PGD phosphogluconate dehydrogenase
PIK3CD-AS1 PIK3CD antisense RNA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PILRA paired immunoglobin-like type 2 receptor alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2D phospholipase A2, group IID
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD4 phospholipase D family, member 4
PLEK pleckstrin
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXND1 plexin D1
PNOC prepronociceptin
POU2AF1 POU class 2 associating factor 1
PRDX1 peroxiredoxin 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTAFR platelet-activating factor receptor
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB20 RAB20, member RAS oncogene family
RAB42 RAB42, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RENBP renin binding protein
RGCC regulator of cell cycle
RNASE6 ribonuclease, RNase A family, k6
RNASET2 ribonuclease T2
RNF166 ring finger protein 166
RNF43 ring finger protein 43
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR4 sphingosine-1-phosphate receptor 4
SCIMP SLP adaptor and CSK interacting membrane protein
SCPEP1 serine carboxypeptidase 1
SCT secretin
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEPT6 septin 6
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPB2 signal-regulatory protein beta 2
SIRPD signal-regulatory protein delta
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC38A6 solute carrier family 38, member 6
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAI3 snail family zinc finger 3
SNORA12 small nucleolar RNA, H/ACA box 12
SNORA5C small nucleolar RNA, H/ACA box 5C
SNX20 sorting nexin 20
SPAG4 sperm associated antigen 4
SPI1 Spi-1 proto-oncogene
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRXN1 sulfiredoxin 1
SSR4 signal sequence receptor, delta
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAC3 SH3 and cysteine rich domain 3
STARD8 StAR-related lipid transfer (START) domain containing 8
STAT4 signal transducer and activator of transcription 4
STXBP5L syntaxin binding protein 5-like
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SVOP SV2 related protein homolog (rat)
TAAR1 trace amine associated receptor 1
TALDO1 transaldolase 1
TARP TCR gamma alternate reading frame protein
TAS1R3 taste receptor, type 1, member 3
TBC1D10C TBC1 domain family, member 10C
TBX21 T-box 21
TCF23 transcription factor 23
TCP10 t-complex 10
TEKT5 tektin 5
TEP1 telomerase-associated protein 1
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR9 toll-like receptor 9
TMEM150B transmembrane protein 150B
TMEM187 transmembrane protein 187
TMEM255A transmembrane protein 255A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TNS2 tensin 2
TOR3A torsin family 3, member A
TPD52L3 tumor protein D52-like 3
TPST2 tyrosylprotein sulfotransferase 2
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM16 tripartite motif containing 16
TRIM16L tripartite motif containing 16-like
TRIM47 tripartite motif containing 47
TSPY4 testis specific protein, Y-linked 4
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TXN thioredoxin
TXNDC11 thioredoxin domain containing 11
TXNRD1 thioredoxin reductase 1
TYROBP TYRO protein tyrosine kinase binding protein
UBA7 ubiquitin-like modifier activating enzyme 7
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UPK3A uroplakin 3A
UTF1 undifferentiated embryonic cell transcription factor 1
VAV1 vav 1 guanine nucleotide exchange factor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WAS Wiskott-Aldrich syndrome
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
XCL2 chemokine (C motif) ligand 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZBP1 Z-DNA binding protein 1