Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

408 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAK1 AP2 associated kinase 1
ABLIM3 actin binding LIM protein family, member 3
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ADGRG6 adhesion G protein-coupled receptor G6
AFAP1L1 actin filament associated protein 1-like 1
AFF4 AF4/FMR2 family, member 4
AGO2 argonaute RISC catalytic component 2
AGRN agrin
AHI1 Abelson helper integration site 1
AK9 adenylate kinase 9
AKR1C8P aldo-keto reductase family 1, member C8, pseudogene
AMPH amphiphysin
ANO4 anoctamin 4
ANXA4 annexin A4
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APOA4 apolipoprotein A-IV
ARFGEF3 ARFGEF family member 3
ARHGAP18 Rho GTPase activating protein 18
ARHGAP21 Rho GTPase activating protein 21
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARSJ arylsulfatase family, member J
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATL3 atlastin GTPase 3
ATP13A2 ATPase type 13A2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATR ATR serine/threonine kinase
AVEN apoptosis, caspase activation inhibitor
B3GAT2 beta-1,3-glucuronyltransferase 2
BAIAP2L2 BAI1-associated protein 2-like 2
BCHE butyrylcholinesterase
BCL7B B-cell CLL/lymphoma 7B
BCL9L B-cell CLL/lymphoma 9-like
BEND7 BEN domain containing 7
BMP15 bone morphogenetic protein 15
BRCA2 breast cancer 2, early onset
BRSK2 BR serine/threonine kinase 2
C15ORF52 chromosome 15 open reading frame 52
C16ORF71 chromosome 16 open reading frame 71
C1ORF159 chromosome 1 open reading frame 159
C1ORF185 chromosome 1 open reading frame 185
C2ORF69 chromosome 2 open reading frame 69
C5ORF34 chromosome 5 open reading frame 34
CA5A carbonic anhydrase VA, mitochondrial
CAB39L calcium binding protein 39-like
CADPS2 Ca++-dependent secretion activator 2
CALU calumenin
CASC4 cancer susceptibility candidate 4
CAST calpastatin
CASZ1 castor zinc finger 1
CCDC112 coiled-coil domain containing 112
CCDC134 coiled-coil domain containing 134
CCDC149 coiled-coil domain containing 149
CCDC169 coiled-coil domain containing 169
CCDC7 coiled-coil domain containing 7
CCPG1 cell cycle progression 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD109 CD109 molecule
CD164 CD164 molecule, sialomucin
CD47 CD47 molecule
CD9 CD9 molecule
CDHR4 cadherin-related family member 4
CDR2 cerebellar degeneration-related protein 2, 62kDa
CENPI centromere protein I
CENPJ centromere protein J
CENPK centromere protein K
CEP104 centrosomal protein 104kDa
CHML choroideremia-like (Rab escort protein 2)
CHRDL1 chordin-like 1
CIB3 calcium and integrin binding family member 3
CLDN9 claudin 9
CLINT1 clathrin interactor 1
CLOCK clock circadian regulator
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COG5 component of oligomeric golgi complex 5
COG6 component of oligomeric golgi complex 6
COL4A5 collagen, type IV, alpha 5
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CPTP ceramide-1-phosphate transfer protein
CPVL carboxypeptidase, vitellogenic-like
CRISP1 cysteine-rich secretory protein 1
CRYAB crystallin, alpha B
CRYBG3 beta-gamma crystallin domain containing 3
CTGF connective tissue growth factor
DAZ2 deleted in azoospermia 2
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFNB31 deafness, autosomal recessive 31
DGKH diacylglycerol kinase, eta
DGKI diacylglycerol kinase, iota
DIAPH3 diaphanous-related formin 3
DLAT dihydrolipoamide S-acetyltransferase
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DMWD dystrophia myotonica, WD repeat containing
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSTN destrin (actin depolymerizing factor)
DTX3L deltex 3 like, E3 ubiquitin ligase
DVL1 dishevelled segment polarity protein 1
ECT2 epithelial cell transforming 2
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF5A2 eukaryotic translation initiation factor 5A2
EMC7 ER membrane protein complex subunit 7
EPS8 epidermal growth factor receptor pathway substrate 8
ESYT2 extended synaptotagmin-like protein 2
ETV1 ets variant 1
EVA1A eva-1 homolog A (C. elegans)
FAM184B family with sequence similarity 184, member B
FAM199X family with sequence similarity 199, X-linked
FAM216B family with sequence similarity 216, member B
FAM65B family with sequence similarity 65, member B
FAM81A family with sequence similarity 81, member A
FBXL17 F-box and leucine-rich repeat protein 17
FBXW11 F-box and WD repeat domain containing 11
FEM1C fem-1 homolog c (C. elegans)
FMO9P flavin containing monooxygenase 9 pseudogene
FOSL1 FOS-like antigen 1
FRMD5 FERM domain containing 5
FRY furry homolog (Drosophila)
FRYL FRY-like
FST follistatin
GATSL2 GATS protein-like 2
GDE1 glycerophosphodiester phosphodiesterase 1
GFM1 G elongation factor, mitochondrial 1
GNRHR gonadotropin-releasing hormone receptor
GOLIM4 golgi integral membrane protein 4
GOLT1B golgi transport 1B
GPR180 G protein-coupled receptor 180
GRAMD3 GRAM domain containing 3
GRK1 G protein-coupled receptor kinase 1
GRK4 G protein-coupled receptor kinase 4
GUCD1 guanylyl cyclase domain containing 1
GYG1 glycogenin 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBS1L HBS1-like translational GTPase
HCCS holocytochrome c synthase
HDAC9 histone deacetylase 9
HIRA histone cell cycle regulator
HMMR hyaluronan-mediated motility receptor (RHAMM)
HRH2 histamine receptor H2
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSF2BP heat shock transcription factor 2 binding protein
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HTRA2 HtrA serine peptidase 2
HUNK hormonally up-regulated Neu-associated kinase
ICMT isoprenylcysteine carboxyl methyltransferase
IFNB1 interferon, beta 1, fibroblast
IL12RB2 interleukin 12 receptor, beta 2
IL6ST interleukin 6 signal transducer
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INA internexin neuronal intermediate filament protein, alpha
INSM2 insulinoma-associated 2
IRS2 insulin receptor substrate 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KALRN kalirin, RhoGEF kinase
KATNAL1 katanin p60 subunit A-like 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KGFLP1 fibroblast growth factor 7 pseudogene
KHDC3L KH domain containing 3-like, subcortical maternal complex member
KIAA0754 KIAA0754
KIAA1328 KIAA1328
KIF1B kinesin family member 1B
KIF2A kinesin heavy chain member 2A
KIF5B kinesin family member 5B
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KPNA3 karyopherin alpha 3 (importin alpha 4)
LARP1 La ribonucleoprotein domain family, member 1
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00028 long intergenic non-protein coding RNA 28
LINC00346 long intergenic non-protein coding RNA 346
LOC100130264 uncharacterized LOC100130264
LOC285593 uncharacterized LOC285593
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPPR2 lipid phosphate phosphatase-related protein type 2
LRP12 low density lipoprotein receptor-related protein 12
LRP2 low density lipoprotein receptor-related protein 2
LRRC2 leucine rich repeat containing 2
LRRC30 leucine rich repeat containing 30
LRRC75A leucine rich repeat containing 75A
LUZP6 leucine zipper protein 6
LYRM1 LYR motif containing 1
LZIC leucine zipper and CTNNBIP1 domain containing
M1AP meiosis 1 associated protein
MAGOHB mago-nashi homolog B (Drosophila)
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBNL3 muscleblind-like splicing regulator 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN2 mucolipin 2
MED23 mediator complex subunit 23
MFN2 mitofusin 2
MFSD6 major facilitator superfamily domain containing 6
MGLL monoglyceride lipase
MIB2 mindbomb E3 ubiquitin protein ligase 2
MID2 midline 2
MINA MYC induced nuclear antigen
MS4A10 membrane-spanning 4-domains, subfamily A, member 10
MTFR2 mitochondrial fission regulator 2
MTMR12 myotubularin related protein 12
MTO1 mitochondrial tRNA translation optimization 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYLK4 myosin light chain kinase family, member 4
MYO6 myosin VI
MZT1 mitotic spindle organizing protein 1
NCAPD3 non-SMC condensin II complex, subunit D3
NDFIP2 Nedd4 family interacting protein 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NLN neurolysin (metallopeptidase M3 family)
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NPSR1 neuropeptide S receptor 1
NRROS negative regulator of reactive oxygen species
NT5E 5'-nucleotidase, ecto (CD73)
NUP98 nucleoporin 98kDa
OCRL oculocerebrorenal syndrome of Lowe
OOEP oocyte expressed protein
OR10P1 olfactory receptor, family 10, subfamily P, member 1
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR2A1 olfactory receptor, family 2, subfamily A, member 1
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OR52B6 olfactory receptor, family 52, subfamily B, member 6
OR5M10 olfactory receptor, family 5, subfamily M, member 10
OR6K2 olfactory receptor, family 6, subfamily K, member 2
OTUD6B OTU domain containing 6B
OXCT1 3-oxoacid CoA transferase 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP4 poly (ADP-ribose) polymerase family, member 4
PAX6 paired box 6
PCDH1 protocadherin 1
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGB4 protocadherin gamma subfamily B, 4
PCNT pericentrin
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE10A phosphodiesterase 10A
PDS5A PDS5 cohesin associated factor A
PEX7 peroxisomal biogenesis factor 7
PGBD4 piggyBac transposable element derived 4
PGM2 phosphoglucomutase 2
PGM5P2 phosphoglucomutase 5 pseudogene 2
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POFUT2 protein O-fucosyltransferase 2
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPARA peroxisome proliferator-activated receptor alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM11 PR domain containing 11
PRDM14 PR domain containing 14
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRRC1 proline-rich coiled-coil 1
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PYGO1 pygopus family PHD finger 1
RAB43 RAB43, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RANBP9 RAN binding protein 9
RAP2A RAP2A, member of RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RECQL RecQ helicase-like
RERE arginine-glutamic acid dipeptide (RE) repeats
REXO2 RNA exonuclease 2
RHPN2 rhophilin, Rho GTPase binding protein 2
RMDN3 regulator of microtubule dynamics 3
RNF11 ring finger protein 11
RNF133 ring finger protein 133
RNF148 ring finger protein 148
RNF6 ring finger protein (C3H2C3 type) 6
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP82 ribosomal protein L23a pseudogene 82
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RRN3P3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3
RSAD2 radical S-adenosyl methionine domain containing 2
RYK receptor-like tyrosine kinase
SAMD9L sterile alpha motif domain containing 9-like
SAR1B secretion associated, Ras related GTPase 1B
SASH1 SAM and SH3 domain containing 1
SC5D sterol-C5-desaturase
SCFD2 sec1 family domain containing 2
SDF4 stromal cell derived factor 4
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEC24A SEC24 family member A
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SETD7 SET domain containing (lysine methyltransferase) 7
SIK2 salt-inducible kinase 2
SLAIN2 SLAIN motif family, member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC35F5 solute carrier family 35, member F5
SLC37A3 solute carrier family 37, member 3
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMAP1 small ArfGAP 1
SMIM14 small integral membrane protein 14
SNED1 sushi, nidogen and EGF-like domains 1
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA59B small nucleolar RNA, H/ACA box 59B
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SRP72 signal recognition particle 72kDa
STIM2 stromal interaction molecule 2
STK39 serine threonine kinase 39
SYBU syntabulin (syntaxin-interacting)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
SYNJ1 synaptojanin 1
SYNJ2 synaptojanin 2
SYPL1 synaptophysin-like 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D23 TBC1 domain family, member 23
TBC1D24 TBC1 domain family, member 24
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBL1Y transducin (beta)-like 1, Y-linked
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL6 transcription elongation factor A (SII)-like 6
TEAD4 TEA domain family member 4
TEX12 testis expressed 12
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM9SF2 transmembrane 9 superfamily member 2
TMCO4 transmembrane and coiled-coil domains 4
TMEM131 transmembrane protein 131
TMEM17 transmembrane protein 17
TMEM171 transmembrane protein 171
TMEM173 transmembrane protein 173
TMEM30A transmembrane protein 30A
TMEM41B transmembrane protein 41B
TMEM55A transmembrane protein 55A
TMEM87A transmembrane protein 87A
TMEM95 transmembrane protein 95
TOPBP1 topoisomerase (DNA) II binding protein 1
TPD52L3 tumor protein D52-like 3
TPGS2 tubulin polyglutamylase complex subunit 2
TPP2 tripeptidyl peptidase II
TRAPPC10 trafficking protein particle complex 10
TRAPPC13 trafficking protein particle complex 13
TRIOBP TRIO and F-actin binding protein
TSPAN7 tetraspanin 7
TTBK2 tau tubulin kinase 2
TTC1 tetratricopeptide repeat domain 1
TUBGCP5 tubulin, gamma complex associated protein 5
UBA5 ubiquitin-like modifier activating enzyme 5
UBA6 ubiquitin-like modifier activating enzyme 6
UBASH3B ubiquitin associated and SH3 domain containing B
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE4B ubiquitination factor E4B
UBIAD1 UbiA prenyltransferase domain containing 1
UBN1 ubinuclein 1
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
USP12 ubiquitin specific peptidase 12
USP18 ubiquitin specific peptidase 18
UVSSA UV-stimulated scaffold protein A
VAMP3 vesicle-associated membrane protein 3
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WDR55 WD repeat domain 55
WNK1 WNK lysine deficient protein kinase 1
WWC2 WW and C2 domain containing 2
XPO4 exportin 4
XPO6 exportin 6
XRN1 5'-3' exoribonuclease 1
YIPF5 Yip1 domain family, member 5
YIPF6 Yip1 domain family, member 6
ZDHHC20 zinc finger, DHHC-type containing 20
ZHX3 zinc fingers and homeoboxes 3
ZNF106 zinc finger protein 106
ZNF148 zinc finger protein 148
ZNF827 zinc finger protein 827
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZNRF4 zinc and ring finger 4
ZW10 zw10 kinetochore protein

low expression

Symbol Name
CCAR2 cell cycle and apoptosis regulator 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
IP6K2 inositol hexakisphosphate kinase 2
RUNDC1 RUN domain containing 1
TTI2 TELO2 interacting protein 2