Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

408 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACKR3 atypical chemokine receptor 3
ACOX2 acyl-CoA oxidase 2, branched chain
ACSS2 acyl-CoA synthetase short-chain family member 2
ACVRL1 activin A receptor type II-like 1
ADAM12 ADAM metallopeptidase domain 12
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAP2 ArfGAP with dual PH domains 2
ADCY4 adenylate cyclase 4
ADCY8 adenylate cyclase 8 (brain)
ADGRG3 adhesion G protein-coupled receptor G3
ADGRL4 adhesion G protein-coupled receptor L4
AFAP1 actin filament associated protein 1
AHR aryl hydrocarbon receptor
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALPL alkaline phosphatase, liver/bone/kidney
AMELX amelogenin, X-linked
APOF apolipoprotein F
ARHGAP29 Rho GTPase activating protein 29
ARHGAP6 Rho GTPase activating protein 6
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
AVPR2 arginine vasopressin receptor 2
BAALC brain and acute leukemia, cytoplasmic
BBS12 Bardet-Biedl syndrome 12
BCL6B B-cell CLL/lymphoma 6, member B
BCO2 beta-carotene oxygenase 2
BFSP1 beaded filament structural protein 1, filensin
BTG2 BTG family, member 2
BTNL2 butyrophilin-like 2
C10ORF82 chromosome 10 open reading frame 82
C11ORF53 chromosome 11 open reading frame 53
C15ORF53 chromosome 15 open reading frame 53
C17ORF98 chromosome 17 open reading frame 98
C1ORF141 chromosome 1 open reading frame 141
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C3ORF36 chromosome 3 open reading frame 36
C4ORF36 chromosome 4 open reading frame 36
C5AR2 complement component 5a receptor 2
C7ORF25 chromosome 7 open reading frame 25
C8ORF48 chromosome 8 open reading frame 48
C9ORF50 chromosome 9 open reading frame 50
CABP4 calcium binding protein 4
CALCRL calcitonin receptor-like
CALHM2 calcium homeostasis modulator 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBWD6 COBW domain containing 6
CCDC141 coiled-coil domain containing 141
CCDC80 coiled-coil domain containing 80
CCM2L cerebral cavernous malformation 2-like
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CD163 CD163 molecule
CD248 CD248 molecule, endosialin
CD300C CD300c molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD93 CD93 molecule
CDH13 cadherin 13
CDH24 cadherin 24, type 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR4 cadherin-related family member 4
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CELA2B chymotrypsin-like elastase family, member 2B
CEP19 centrosomal protein 19kDa
CETP cholesteryl ester transfer protein, plasma
CFAP47 cilia and flagella associated protein 47
CFAP74 cilia and flagella associated protein 74
CFH complement factor H
CFHR3 complement factor H-related 3
CGNL1 cingulin-like 1
CHRDL1 chordin-like 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLCN4 chloride channel, voltage-sensitive 4
CLDND2 claudin domain containing 2
CLEC14A C-type lectin domain family 14, member A
CLEC3B C-type lectin domain family 3, member B
CLIC5 chloride intracellular channel 5
CLSTN3 calsyntenin 3
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CNPY4 canopy FGF signaling regulator 4
CNTNAP4 contactin associated protein-like 4
COG7 component of oligomeric golgi complex 7
COL21A1 collagen, type XXI, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COTL1 coactosin-like F-actin binding protein 1
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRLF2 cytokine receptor-like factor 2
CRYBA4 crystallin, beta A4
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP1 cysteine and glycine-rich protein 1
CT62 cancer/testis antigen 62
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CXORF36 chromosome X open reading frame 36
CYBB cytochrome b-245, beta polypeptide
CYYR1 cysteine/tyrosine-rich 1
DCN decorin
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DERL3 derlin 3
DGKB diacylglycerol kinase, beta 90kDa
DIXDC1 DIX domain containing 1
DNMBP-AS1 DNMBP antisense RNA 1
DOCK4 dedicator of cytokinesis 4
DRD3 dopamine receptor D3
DYSF dysferlin
EBF1 early B-cell factor 1
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFCAB13 EF-hand calcium binding domain 13
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
ELN elastin
EMILIN1 elastin microfibril interfacer 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERLEC1 endoplasmic reticulum lectin 1
ESAM endothelial cell adhesion molecule
EXOC3L1 exocyst complex component 3-like 1
EXOC3L2 exocyst complex component 3-like 2
EYA1 EYA transcriptional coactivator and phosphatase 1
F13B coagulation factor XIII, B polypeptide
FAM124B family with sequence similarity 124B
FAM198A family with sequence similarity 198, member A
FAM212B family with sequence similarity 212, member B
FAM222A family with sequence similarity 222, member A
FAM46C family with sequence similarity 46, member C
FAM71C family with sequence similarity 71, member C
FAM74A1 family with sequence similarity 74, member A1
FAM74A3 family with sequence similarity 74, member A3
FAM84B family with sequence similarity 84, member B
FANCL Fanconi anemia, complementation group L
FAT4 FAT atypical cadherin 4
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCRLA Fc receptor-like A
FGD5 FYVE, RhoGEF and PH domain containing 5
FGFR1 fibroblast growth factor receptor 1
FGL2 fibrinogen-like 2
FICD FIC domain containing
FLT1 fms-related tyrosine kinase 1
FMOD fibromodulin
FNDC7 fibronectin type III domain containing 7
FOXI2 forkhead box I2
FPR1 formyl peptide receptor 1
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATA4 GATA binding protein 4
GDNF glial cell derived neurotrophic factor
GFRAL GDNF family receptor alpha like
GIMAP8 GTPase, IMAP family member 8
GJA5 gap junction protein, alpha 5, 40kDa
GLG1 golgi glycoprotein 1
GLT8D1 glycosyltransferase 8 domain containing 1
GLT8D2 glycosyltransferase 8 domain containing 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNS glucosamine (N-acetyl)-6-sulfatase
GPR4 G protein-coupled receptor 4
GSAP gamma-secretase activating protein
HBD hemoglobin, delta
HCG22 HLA complex group 22
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HEG1 heart development protein with EGF-like domains 1
HIGD1B HIG1 hypoxia inducible domain family, member 1B
HIST1H4K histone cluster 1, H4k
HK3 hexokinase 3 (white cell)
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRASLS2 HRAS-like suppressor 2
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IFNA5 interferon, alpha 5
IFNAR2 interferon (alpha, beta and omega) receptor 2
IL10RB interleukin 10 receptor, beta
IL15RA interleukin 15 receptor, alpha
IRAK2 interleukin-1 receptor-associated kinase 2
ITGA11 integrin, alpha 11
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
JSRP1 junctional sarcoplasmic reticulum protein 1
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNT2 potassium channel, sodium activated subfamily T, member 2
KCTD6 potassium channel tetramerization domain containing 6
KIAA0408 KIAA0408
KIAA1462 KIAA1462
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
LAMA4 laminin, alpha 4
LAMB1 laminin, beta 1
LAX1 lymphocyte transmembrane adaptor 1
LBP lipopolysaccharide binding protein
LCN6 lipocalin 6
LHX5 LIM homeobox 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00092 long intergenic non-protein coding RNA 92
LINC00305 long intergenic non-protein coding RNA 305
LINC01600 long intergenic non-protein coding RNA 1600
LOC100130872 uncharacterized LOC100130872
LOC100131496 uncharacterized LOC100131496
LOC153910 uncharacterized LOC153910
LOC154761 family with sequence similarity 115, member C pseudogene
LOC642929 general transcription factor II, i pseudogene
LPIN2 lipin 2
LRGUK leucine-rich repeats and guanylate kinase domain containing
LRRC25 leucine rich repeat containing 25
LUM lumican
MAATS1 MYCBP-associated, testis expressed 1
MBOAT4 membrane bound O-acyltransferase domain containing 4
MBTPS2 membrane-bound transcription factor peptidase, site 2
MERTK MER proto-oncogene, tyrosine kinase
MESTIT1 MEST intronic transcript 1, antisense RNA
MFAP5 microfibrillar associated protein 5
MFSD1 major facilitator superfamily domain containing 1
MIR99AHG mir-99a-let-7c cluster host gene
MIXL1 Mix paired-like homeobox
MLKL mixed lineage kinase domain-like
MMP23A matrix metallopeptidase 23A (pseudogene)
MMRN2 multimerin 2
MNDA myeloid cell nuclear differentiation antigen
MPEG1 macrophage expressed 1
MRC1 mannose receptor, C type 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTTP microsomal triglyceride transfer protein
MXRA5 matrix-remodelling associated 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO7A myosin VIIA
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NAAA N-acylethanolamine acid amidase
NANOS2 nanos homolog 2 (Drosophila)
NAV1 neuron navigator 1
NEUROG2 neurogenin 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L3 nuclear factor, erythroid 2-like 3
NHEG1 neuroblastoma highly expressed 1
NID2 nidogen 2 (osteonidogen)
NLRC4 NLR family, CARD domain containing 4
NOTCH4 notch 4
NOX1 NADPH oxidase 1
NPR1 natriuretic peptide receptor 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP2 nuclear receptor interacting protein 2
NTN4 netrin 4
NXPH3 neurexophilin 3
OIT3 oncoprotein induced transcript 3
OR13C4 olfactory receptor, family 13, subfamily C, member 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR4C13 olfactory receptor, family 4, subfamily C, member 13
OR4D11 olfactory receptor, family 4, subfamily D, member 11
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR52N1 olfactory receptor, family 52, subfamily N, member 1
OR56A5 olfactory receptor, family 56, subfamily A, member 5
OR6W1P olfactory receptor, family 6, subfamily W, member 1 pseudogene
OR8B12 olfactory receptor, family 8, subfamily B, member 12
OR8G5 olfactory receptor, family 8, subfamily G, member 5
OTOR otoraplin
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PCDH12 protocadherin 12
PCDHGB6 protocadherin gamma subfamily B, 6
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE11A phosphodiesterase 11A
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PI16 peptidase inhibitor 16
PKD2L2 polycystic kidney disease 2-like 2
PKDCC protein kinase domain containing, cytoplasmic
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G5 phospholipase A2, group V
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PLEK pleckstrin
PLET1 placenta expressed transcript 1
PLN phospholamban
PLVAP plasmalemma vesicle associated protein
PNLIP pancreatic lipase
PNLIPRP1 pancreatic lipase-related protein 1
POPDC2 popeye domain containing 2
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B
PRG4 proteoglycan 4
PRM3 protamine 3
PROCA1 protein interacting with cyclin A1
PROX1 prospero homeobox 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMY3AP RNA binding motif protein, Y-linked, family 3, member A pseudogene
RELN reelin
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGMA repulsive guidance molecule family member a
RIN2 Ras and Rab interactor 2
RIPPLY1 ripply transcriptional repressor 1
RNF133 ring finger protein 133
RUNX1-IT1 RUNX1 intronic transcript 1
RXFP4 relaxin/insulin-like family peptide receptor 4
SCARF1 scavenger receptor class F, member 1
SCARNA8 small Cajal body-specific RNA 8
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDC2 syndecan 2
SEC24D SEC24 family member D
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SFRP4 secreted frizzled-related protein 4
SFTA1P surfactant associated 1, pseudogene
SH2B3 SH2B adaptor protein 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLX4IP SLX4 interacting protein
SMAD3 SMAD family member 3
SMTN smoothelin
SNORA22 small nucleolar RNA, H/ACA box 22
SNORA44 small nucleolar RNA, H/ACA box 44
SNORA53 small nucleolar RNA, H/ACA box 53
SNORA74A small nucleolar RNA, H/ACA box 74A
SNORA75 small nucleolar RNA, H/ACA box 75
SOBP sine oculis binding protein homolog (Drosophila)
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRPX2 sushi-repeat containing protein, X-linked 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAB1 stabilin 1
STARD8 StAR-related lipid transfer (START) domain containing 8
STIM2 stromal interaction molecule 2
STK31 serine/threonine kinase 31
STXBP5L syntaxin binding protein 5-like
SYTL4 synaptotagmin-like 4
TAS1R3 taste receptor, type 1, member 3
TAS2R30 taste receptor, type 2, member 30
TAS2R42 taste receptor, type 2, member 42
TAS2R43 taste receptor, type 2, member 43
TCF23 transcription factor 23
TCP10 t-complex 10
TESC tescalcin
TEX33 testis expressed 33
TEX35 testis expressed 35
TEX43 testis expressed 43
TF transferrin
TGFB3 transforming growth factor, beta 3
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
TGM2 transglutaminase 2
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TIAM2 T-cell lymphoma invasion and metastasis 2
TM4SF5 transmembrane 4 L six family member 5
TMED4 transmembrane emp24 protein transport domain containing 4
TMEM150B transmembrane protein 150B
TMEM252 transmembrane protein 252
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNNI1 troponin I type 1 (skeletal, slow)
TNS2 tensin 2
TNXB tenascin XB
TOR1B torsin family 1, member B (torsin B)
TP53TG5 TP53 target 5
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTLL8 tubulin tyrosine ligase-like family member 8
TTN titin
TXNDC11 thioredoxin domain containing 11
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
UCN3 urocortin 3
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
USHBP1 Usher syndrome 1C binding protein 1
VAMP5 vesicle-associated membrane protein 5
VGLL3 vestigial-like family member 3
VIT vitrin
VSIG10 V-set and immunoglobulin domain containing 10
VTN vitronectin
WISP3 WNT1 inducible signaling pathway protein 3
WNT2 wingless-type MMTV integration site family member 2
WNT9B wingless-type MMTV integration site family, member 9B
XBP1 X-box binding protein 1
XCR1 chemokine (C motif) receptor 1
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZNF117 zinc finger protein 117
ZNF366 zinc finger protein 366