Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A6-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

337 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A6-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL6 acyl-CoA synthetase long-chain family member 6
ACSS1 acyl-CoA synthetase short-chain family member 1
ADGRG2 adhesion G protein-coupled receptor G2
AGFG1 ArfGAP with FG repeats 1
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12
AMZ2P1 archaelysin family metallopeptidase 2 pseudogene 1
ANKRD37 ankyrin repeat domain 37
ANKRD39 ankyrin repeat domain 39
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
ARL17B ADP-ribosylation factor-like 17B
ASXL1 additional sex combs like transcriptional regulator 1
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
AUTS2 autism susceptibility candidate 2
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BCAR1 breast cancer anti-estrogen resistance 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BHLHE40 basic helix-loop-helix family, member e40
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C20ORF195 chromosome 20 open reading frame 195
C2ORF76 chromosome 2 open reading frame 76
C2ORF88 chromosome 2 open reading frame 88
CA5A carbonic anhydrase VA, mitochondrial
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALML6 calmodulin-like 6
CCDC7 coiled-coil domain containing 7
CCSAP centriole, cilia and spindle-associated protein
CDC14C cell division cycle 14C
CEP152 centrosomal protein 152kDa
CEP95 centrosomal protein 95kDa
CGNL1 cingulin-like 1
CLASP1 cytoplasmic linker associated protein 1
CLEC2B C-type lectin domain family 2, member B
COL27A1 collagen, type XXVII, alpha 1
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
COX5B cytochrome c oxidase subunit Vb
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTTNBP2 cortactin binding protein 2
CUL3 cullin 3
CYBRD1 cytochrome b reductase 1
CYCS cytochrome c, somatic
CYGB cytoglobin
CYTH3 cytohesin 3
DAPK1 death-associated protein kinase 1
DCAF6 DDB1 and CUL4 associated factor 6
DCLRE1C DNA cross-link repair 1C
DDHD2 DDHD domain containing 2
DDIT4 DNA-damage-inducible transcript 4
DGKG diacylglycerol kinase, gamma 90kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25
DNM1P46 dynamin 1 pseudogene 46
DNPEP aspartyl aminopeptidase
DOCK10 dedicator of cytokinesis 10
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DSN1 DSN1, MIS12 kinetochore complex component
DSTYK dual serine/threonine and tyrosine protein kinase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP5P1 dual specificity phosphatase 5 pseudogene 1
EFCAB3 EF-hand calcium binding domain 3
EFR3B EFR3 homolog B (S. cerevisiae)
EGLN1 egl-9 family hypoxia-inducible factor 1
EP300 E1A binding protein p300
ERO1L ERO1-like (S. cerevisiae)
FAM126B family with sequence similarity 126, member B
FAM95B1 family with sequence similarity 95, member B1
FARSB phenylalanyl-tRNA synthetase, beta subunit
FITM2 fat storage-inducing transmembrane protein 2
FN3KRP fructosamine 3 kinase related protein
FXYD3 FXYD domain containing ion transport regulator 3
FXYD6 FXYD domain containing ion transport regulator 6
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAS2L3 growth arrest-specific 2 like 3
GAS8-AS1 GAS8 antisense RNA 1
GDF11 growth differentiation factor 11
GDF2 growth differentiation factor 2
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR155 G protein-coupled receptor 155
GRAMD4 GRAM domain containing 4
GTF2IRD2 GTF2I repeat domain containing 2
GTPBP10 GTP-binding protein 10 (putative)
GZF1 GDNF-inducible zinc finger protein 1
HACD4 3-hydroxyacyl-CoA dehydratase 4
HAR1A highly accelerated region 1A (non-protein coding)
HAR1B highly accelerated region 1B (non-protein coding)
HBP1 HMG-box transcription factor 1
HIBADH 3-hydroxyisobutyrate dehydrogenase
HILPDA hypoxia inducible lipid droplet-associated
HIP1 huntingtin interacting protein 1
HIST1H2AB histone cluster 1, H2ab
HIST1H2AG histone cluster 1, H2ag
HIST4H4 histone cluster 4, H4
HSF4 heat shock transcription factor 4
IFRD1 interferon-related developmental regulator 1
IL18R1 interleukin 18 receptor 1
IL22 interleukin 22
IL3 interleukin 3
INSIG2 insulin induced gene 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRS1 insulin receptor substrate 1
ISCU iron-sulfur cluster assembly enzyme
KATNAL2 katanin p60 subunit A-like 2
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDM3A lysine (K)-specific demethylase 3A
KLF14 Kruppel-like factor 14
KLHDC10 kelch domain containing 10
KMT2E lysine (K)-specific methyltransferase 2E
KRTAP6-2 keratin associated protein 6-2
LHFPL3 lipoma HMGIC fusion partner-like 3
LHX5 LIM homeobox 5
LHX6 LIM homeobox 6
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LIMD1 LIM domains containing 1
LINC00312 long intergenic non-protein coding RNA 312
LIPT1 lipoyltransferase 1
LOC100128573 uncharacterized LOC100128573
LOC100190986 uncharacterized LOC100190986
LOC143666 uncharacterized LOC143666
LOC154761 family with sequence similarity 115, member C pseudogene
LOC283856 uncharacterized LOC283856
LOC374443 C-type lectin domain family 2, member D pseudogene
LOC90834
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP2 low density lipoprotein receptor-related protein 2
MAP2 microtubule-associated protein 2
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK11 mitogen-activated protein kinase 11
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAVS mitochondrial antiviral signaling protein
MCM8 minichromosome maintenance complex component 8
MCOLN3 mucolipin 3
MEGF6 multiple EGF-like-domains 6
MEIOB meiosis specific with OB domains
MFF mitochondrial fission factor
MFSD6 major facilitator superfamily domain containing 6
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MGME1 mitochondrial genome maintenance exonuclease 1
MITD1 MIT, microtubule interacting and transport, domain containing 1
MKKS McKusick-Kaufman syndrome
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MON2 MON2 homolog (S. cerevisiae)
MREG melanoregulin
MRPL44 mitochondrial ribosomal protein L44
MRPS5 mitochondrial ribosomal protein S5
MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1
MTVR2 mouse mammary tumor virus receptor homolog 2
MYH10 myosin, heavy chain 10, non-muscle
MYO1B myosin IB
NAMPT nicotinamide phosphoribosyltransferase
NANP N-acetylneuraminic acid phosphatase
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NCK2 NCK adaptor protein 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NHEJ1 nonhomologous end-joining factor 1
NINL ninein-like
NKX2-6 NK2 homeobox 6
NLRP6 NLR family, pyrin domain containing 6
NPEPPS aminopeptidase puromycin sensitive
NUB1 negative regulator of ubiquitin-like proteins 1
OPTN optineurin
OR10W1 olfactory receptor, family 10, subfamily W, member 1
OR2B11 olfactory receptor, family 2, subfamily B, member 11
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR2M1P olfactory receptor, family 2, subfamily M, member 1 pseudogene
OR2M5 olfactory receptor, family 2, subfamily M, member 5
OR2T27 olfactory receptor, family 2, subfamily T, member 27
OR4F4 olfactory receptor, family 4, subfamily F, member 4
OR6M1 olfactory receptor, family 6, subfamily M, member 1
OSBPL3 oxysterol binding protein-like 3
PANK2 pantothenate kinase 2
PANX2 pannexin 2
PAQR5 progestin and adipoQ receptor family member V
PCDHGB8P protocadherin gamma subfamily B, 8 pseudogene
PCED1A PC-esterase domain containing 1A
PCNA proliferating cell nuclear antigen
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDZD4 PDZ domain containing 4
PECR peroxisomal trans-2-enoyl-CoA reductase
PGBD5 piggyBac transposable element derived 5
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PKP4 plakophilin 4
PLXNC1 plexin C1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNKD paroxysmal nonkinesigenic dyskinesia
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene)
PRKG2 protein kinase, cGMP-dependent, type II
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRR34 proline rich 34
PTCH1 patched 1
PYCARD PYD and CARD domain containing
RAB22A RAB22A, member RAS oncogene family
RAB24 RAB24, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD21L1 RAD21-like 1 (S. pombe)
RAI1 retinoic acid induced 1
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RANBP10 RAN binding protein 10
RAP1GAP RAP1 GTPase activating protein
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASEF RAS and EF-hand domain containing
RAX2 retina and anterior neural fold homeobox 2
RBM33 RNA binding motif protein 33
RBM48 RNA binding motif protein 48
RELL2 RELT-like 2
RGS9BP regulator of G protein signaling 9 binding protein
RHBDD1 rhomboid domain containing 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RNF114 ring finger protein 114
RNF24 ring finger protein 24
RPL23AP64 ribosomal protein L23a pseudogene 64
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RTN4RL1 reticulon 4 receptor-like 1
SCARNA9 small Cajal body-specific RNA 9
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPT11 septin 11
SEPT3 septin 3
SFT2D3 SFT2 domain containing 3
SGK223 homolog of rat pragma of Rnd2
SH3BP4 SH3-domain binding protein 4
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMCR5 Smith-Magenis syndrome chromosome region, candidate 5 (non-protein coding)
SND1-IT1 SND1 intronic transcript 1
SNPH syntaphilin
SNRK SNF related kinase
SNX5 sorting nexin 5
SP1 Sp1 transcription factor
SPDYE1 speedy/RINGO cell cycle regulator family member E1
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SPDYE5 speedy/RINGO cell cycle regulator family member E5
SPDYE6 speedy/RINGO cell cycle regulator family member E6
SPDYE7P speedy/RINGO cell cycle regulator family member E7, pseudogene
SPIRE2 spire-type actin nucleation factor 2
SRPK2 SRSF protein kinase 2
SRRM3 serine/arginine repetitive matrix 3
SSMEM1 serine-rich single-pass membrane protein 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK10 serine/threonine kinase 10
STK36 serine/threonine kinase 36
STMN3 stathmin-like 3
STXBP1 syntaxin binding protein 1
SYCP2 synaptonemal complex protein 2
SYPL1 synaptophysin-like 1
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TAS2R14 taste receptor, type 2, member 14
TAS2R20 taste receptor, type 2, member 20
TAS2R42 taste receptor, type 2, member 42
TAS2R43 taste receptor, type 2, member 43
TASP1 taspase, threonine aspartase, 1
TBC1D20 TBC1 domain family, member 20
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCHP trichoplein, keratin filament binding
TDRKH tudor and KH domain containing
TEDDM1 transmembrane epididymal protein 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TM7SF3 transmembrane 7 superfamily member 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM114 transmembrane protein 114
TMEM171 transmembrane protein 171
TMEM209 transmembrane protein 209
TMEM230 transmembrane protein 230
TMEM245 transmembrane protein 245
TMEM30C transmembrane protein 30C
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TNIK TRAF2 and NCK interacting kinase
TNRC18 trinucleotide repeat containing 18
TNS1 tensin 1
TPCN1 two pore segment channel 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM24 tripartite motif containing 24
TRIM47 tripartite motif containing 47
TRIM65 tripartite motif containing 65
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSHZ1 teashirt zinc finger homeobox 1
TTC21B tetratricopeptide repeat domain 21B
TYW5 tRNA-yW synthesizing protein 5
UBE3C ubiquitin protein ligase E3C
UGCG UDP-glucose ceramide glucosyltransferase
UHMK1 U2AF homology motif (UHM) kinase 1
UNC13A unc-13 homolog A (C. elegans)
USP17L6P ubiquitin specific peptidase 17-like family member 6, pseudogene
USP37 ubiquitin specific peptidase 37
VLDLR very low density lipoprotein receptor
VSIG10 V-set and immunoglobulin domain containing 10
VSTM1 V-set and transmembrane domain containing 1
WASL Wiskott-Aldrich syndrome-like
WDFY1 WD repeat and FYVE domain containing 1
WDR38 WD repeat domain 38
WDR60 WD repeat domain 60
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRN2 5'-3' exoribonuclease 2
ZADH2 zinc binding alcohol dehydrogenase domain containing 2
ZC3H6 zinc finger CCCH-type containing 6
ZG16 zymogen granule protein 16
ZNF142 zinc finger protein 142
ZNF337 zinc finger protein 337
ZNFX1 zinc finger, NFX1-type containing 1
ZNRF4 zinc and ring finger 4

low expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
OSGEP O-sialoglycoprotein endopeptidase
PPP1R7 protein phosphatase 1, regulatory subunit 7