Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

301 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD15 abhydrolase domain containing 15
ABLIM2 actin binding LIM protein family, member 2
ACAA2 acetyl-CoA acyltransferase 2
ADCY1 adenylate cyclase 1 (brain)
AGRN agrin
AHNAK2 AHNAK nucleoprotein 2
AKAP3 A kinase (PRKA) anchor protein 3
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALPPL2 alkaline phosphatase, placental-like 2
AMOT angiomotin
ANO8 anoctamin 8
ANXA4 annexin A4
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ASB13 ankyrin repeat and SOCS box containing 13
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT1
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BMP8A bone morphogenetic protein 8a
BMPR1B bone morphogenetic protein receptor, type IB
BPHL biphenyl hydrolase-like (serine hydrolase)
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRSK2 BR serine/threonine kinase 2
C1ORF226 chromosome 1 open reading frame 226
C1ORF43 chromosome 1 open reading frame 43
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALHM3 calcium homeostasis modulator 3
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPN2 calpain 2, (m/II) large subunit
CASC10 cancer susceptibility candidate 10
CCDC85B coiled-coil domain containing 85B
CCR10 chemokine (C-C motif) receptor 10
CD2AP CD2-associated protein
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLDN9 claudin 9
CLN3 ceroid-lipofuscinosis, neuronal 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CPLX1 complexin 1
CPNE2 copine II
CRIP2 cysteine-rich protein 2
CRTAP cartilage associated protein
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTXN2 cortexin 2
CUL7 cullin 7
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDB2 damage-specific DNA binding protein 2, 48kDa
DDR2 discoidin domain receptor tyrosine kinase 2
DDX11L2 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 2
DEAF1 DEAF1 transcription factor
DEFB131 defensin, beta 131
DHRS7 dehydrogenase/reductase (SDR family) member 7
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRC1 disrupted in renal carcinoma 1
DNAH12 dynein, axonemal, heavy chain 12
DQX1 DEAQ box RNA-dependent ATPase 1
DSCR10 Down syndrome critical region 10 (non-protein coding)
DSCR8 Down syndrome critical region 8
DYM dymeclin
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EFNA4 ephrin-A4
EGR4 early growth response 4
ELAC1 elaC ribonuclease Z 1
EML5 echinoderm microtubule associated protein like 5
ENHO energy homeostasis associated
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
EXD2 exonuclease 3'-5' domain containing 2
FAF1 Fas (TNFRSF6) associated factor 1
FAM167B family with sequence similarity 167, member B
FAM20B family with sequence similarity 20, member B
FAM35A family with sequence similarity 35, member A
FAM35BP family with sequence similarity 35, member A pseudogene
FAM35DP family with sequence similarity 35, member A pseudogene
FAM90A1 family with sequence similarity 90, member A1
FBXL2 F-box and leucine-rich repeat protein 2
FBXO2 F-box protein 2
FBXO45 F-box protein 45
FECH ferrochelatase
FHOD1 formin homology 2 domain containing 1
FLNA filamin A, alpha
FLOT1 flotillin 1
FSD2 fibronectin type III and SPRY domain containing 2
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
GPR19 G protein-coupled receptor 19
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GUSBP2 glucuronidase, beta pseudogene 2
GUSBP3 glucuronidase, beta pseudogene 3
HARBI1 harbinger transposase derived 1
HBQ1 hemoglobin, theta 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDGF hepatoma-derived growth factor
HIST1H3H histone cluster 1, H3h
HK1 hexokinase 1
HN1L hematological and neurological expressed 1-like
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HSPA4L heat shock 70kDa protein 4-like
IDUA iduronidase, alpha-L-
INF2 inverted formin, FH2 and WH2 domain containing
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INPP5F inositol polyphosphate-5-phosphatase F
INSM2 insulinoma-associated 2
IPO11 importin 11
IRS1 insulin receptor substrate 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPK1-AS1 ITPK1 antisense RNA 1
JAGN1 jagunal homolog 1 (Drosophila)
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KDM1B lysine (K)-specific demethylase 1B
KDSR 3-ketodihydrosphingosine reductase
KHK ketohexokinase (fructokinase)
KIAA1161 KIAA1161
KIAA1715 KIAA1715
KLC2 kinesin light chain 2
KLHL40 kelch-like family member 40
LHFPL4 lipoma HMGIC fusion partner-like 4
LIMD1 LIM domains containing 1
LINC00235 long intergenic non-protein coding RNA 235
LINC01011 long intergenic non-protein coding RNA 1011
LINC01547 long intergenic non-protein coding RNA 1547
LINC01588 long intergenic non-protein coding RNA 1588
LOC401052 uncharacterized LOC401052
LOC441601 septin 7 pseudogene
LRRC1 leucine rich repeat containing 1
LRRC16A leucine rich repeat containing 16A
LRRC24 leucine rich repeat containing 24
LRRC37A3 leucine rich repeat containing 37, member A3
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LRRTM4 leucine rich repeat transmembrane neuronal 4
MANBA mannosidase, beta A, lysosomal
MANEAL mannosidase, endo-alpha-like
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK11 mitogen-activated protein kinase 11
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
METTL21A methyltransferase like 21A
MIF4GD MIF4G domain containing
MMP13 matrix metallopeptidase 13
MPZL1 myelin protein zero-like 1
MRAS muscle RAS oncogene homolog
MRGPRG-AS1 MRGPRG antisense RNA 1
MROH9 maestro heat-like repeat family member 9
MSRB3 methionine sulfoxide reductase B3
MYO18A myosin XVIIIA
NANOS1 nanos homolog 1 (Drosophila)
NAPRT nicotinate phosphoribosyltransferase
NARS asparaginyl-tRNA synthetase
NGLY1 N-glycanase 1
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NME1-NME2 NME1-NME2 readthrough
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX3 NADPH oxidase 3
NPM3 nucleophosmin/nucleoplasmin 3
NPTXR neuronal pentraxin receptor
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUP210L nucleoporin 210kDa-like
NUTM2D NUT family member 2D
OGG1 8-oxoguanine DNA glycosylase
OLFM2 olfactomedin 2
OR10J5 olfactory receptor, family 10, subfamily J, member 5
OR13C8 olfactory receptor, family 13, subfamily C, member 8
OXSM 3-oxoacyl-ACP synthase, mitochondrial
OXSR1 oxidative stress responsive 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PANK1 pantothenate kinase 1
PARD6A par-6 family cell polarity regulator alpha
PCDHA1 protocadherin alpha 1
PCDHA4 protocadherin alpha 4
PCDHA6 protocadherin alpha 6
PCNXL4 pecanex-like 4 (Drosophila)
PDCD11 programmed cell death 11
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PKN1 protein kinase N1
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PMVK phosphomevalonate kinase
PNMA1 paraneoplastic Ma antigen 1
PNPLA6 patatin-like phospholipase domain containing 6
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLH polymerase (DNA directed), eta
PPAN peter pan homolog (Drosophila)
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP1R2P3 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3
PRAMEF14 PRAME family member 14
PTCHD4 patched domain containing 4
PYGB phosphorylase, glycogen; brain
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD17 RAD17 homolog (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBM8A RNA binding motif protein 8A
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
REEP1 receptor accessory protein 1
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF150 ring finger protein 150
RPLP0P2 ribosomal protein, large, P0 pseudogene 2
RPSA ribosomal protein SA
RPSAP58 ribosomal protein SA pseudogene 58
RPUSD3 RNA pseudouridylate synthase domain containing 3
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RTN3 reticulon 3
RTN4RL2 reticulon 4 receptor-like 2
RTP1 receptor (chemosensory) transporter protein 1
S100A16 S100 calcium binding protein A16
S100A4 S100 calcium binding protein A4
S1PR2 sphingosine-1-phosphate receptor 2
SAC3D1 SAC3 domain containing 1
SAMD1 sterile alpha motif domain containing 1
SCHIP1 schwannomin interacting protein 1
SCRIB scribbled planar cell polarity protein
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERTAD4-AS1 SERTAD4 antisense RNA 1
SETD3 SET domain containing 3
SETMAR SET domain and mariner transposase fusion gene
SH2D5 SH2 domain containing 5
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3D19 SH3 domain containing 19
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC45A4 solute carrier family 45, member 4
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMAD2 SMAD family member 2
SMAD6 SMAD family member 6
SNX27 sorting nexin family member 27
SOX13 SRY (sex determining region Y)-box 13
SRCIN1 SRC kinase signaling inhibitor 1
SUMF1 sulfatase modifying factor 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SVIL supervillin
SYCE2 synaptonemal complex central element protein 2
SYP synaptophysin
SYT17 synaptotagmin XVII
SYT7 synaptotagmin VII
TADA3 transcriptional adaptor 3
TBC1D14 TBC1 domain family, member 14
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TEX19 testis expressed 19
TIGD3 tigger transposable element derived 3
TLE6 transducin-like enhancer of split 6
TMCO2 transmembrane and coiled-coil domains 2
TMEM151A transmembrane protein 151A
TMEM180 transmembrane protein 180
TMEM206 transmembrane protein 206
TMEM251 transmembrane protein 251
TMEM253 transmembrane protein 253
TMEM43 transmembrane protein 43
TMPPE transmembrane protein with metallophosphoesterase domain
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPM1 tropomyosin 1 (alpha)
TRAM1L1 translocation associated membrane protein 1-like 1
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSPAN14 tetraspanin 14
UBP1 upstream binding protein 1 (LBP-1a)
USP31 ubiquitin specific peptidase 31
USP6NL USP6 N-terminal like
WDR6 WD repeat domain 6
WDR63 WD repeat domain 63
XAGE1E X antigen family, member 1E
XRRA1 X-ray radiation resistance associated 1
XXYLT1 xyloside xylosyltransferase 1
XYLB xylulokinase homolog (H. influenzae)
ZNF219 zinc finger protein 219
ZNF716 zinc finger protein 716
ZNF718 zinc finger protein 718

low expression

Symbol Name
C14ORF169 chromosome 14 open reading frame 169
CHST10 carbohydrate sulfotransferase 10
GLOD4 glyoxalase domain containing 4
HNRNPL heterogeneous nuclear ribonucleoprotein L
LDHB lactate dehydrogenase B
TMEM62 transmembrane protein 62
UBB ubiquitin B