Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

345 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABHD15 abhydrolase domain containing 15
ACACA acetyl-CoA carboxylase alpha
ACLY ATP citrate lyase
ADAM22 ADAM metallopeptidase domain 22
AFF1 AF4/FMR2 family, member 1
AGA aspartylglucosaminidase
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP10 A kinase (PRKA) anchor protein 10
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALPK1 alpha-kinase 1
ANAPC10 anaphase promoting complex subunit 10
ANK2 ankyrin 2, neuronal
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD40 ankyrin repeat domain 40
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANXA5 annexin A5
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APOE apolipoprotein E
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ASB16-AS1 ASB16 antisense RNA 1
ASIC3 acid sensing (proton gated) ion channel 3
ATG5 autophagy related 5
B2M beta-2-microglobulin
BCAS3 breast carcinoma amplified sequence 3
BPGM 2,3-bisphosphoglycerate mutase
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C10ORF53 chromosome 10 open reading frame 53
C15ORF53 chromosome 15 open reading frame 53
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF21 chromosome 1 open reading frame 21
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C4ORF17 chromosome 4 open reading frame 17
C4ORF33 chromosome 4 open reading frame 33
C6ORF58 chromosome 6 open reading frame 58
C7ORF31 chromosome 7 open reading frame 31
C7ORF49 chromosome 7 open reading frame 49
CALCOCO2 calcium binding and coiled-coil domain 2
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2
CAPS2 calcyphosine 2
CAV2 caveolin 2
CCDC28A coiled-coil domain containing 28A
CCDC50 coiled-coil domain containing 50
CCDC62 coiled-coil domain containing 62
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCNG2 cyclin G2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8A CD8a molecule
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP162 centrosomal protein 162kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIITA class II, major histocompatibility complex, transactivator
CLCNKA chloride channel, voltage-sensitive Ka
CLIC2 chloride intracellular channel 2
CLLU1 chronic lymphocytic leukemia up-regulated 1
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CPD carboxypeptidase D
CPXCR1 CPX chromosome region, candidate 1
CT55 cancer/testis antigen 55
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTNNA2 catenin (cadherin-associated protein), alpha 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CYYR1 cysteine/tyrosine-rich 1
DAAM2 dishevelled associated activator of morphogenesis 2
DBP D site of albumin promoter (albumin D-box) binding protein
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DDO D-aspartate oxidase
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAAF3 dynein, axonemal, assembly factor 3
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNASE1 deoxyribonuclease I
DRAM1 DNA-damage regulated autophagy modulator 1
DSCR8 Down syndrome critical region 8
EBI3 Epstein-Barr virus induced 3
ECT2L epithelial cell transforming 2 like
EDNRB endothelin receptor type B
ENOPH1 enolase-phosphatase 1
EOMES eomesodermin
EPHA5 EPH receptor A5
ERICH4 glutamate-rich 4
ERP27 endoplasmic reticulum protein 27
EXOC1 exocyst complex component 1
FAM133A family with sequence similarity 133, member A
FAM149A family with sequence similarity 149, member A
FAM163B family with sequence similarity 163, member B
FAM198B family with sequence similarity 198, member B
FAM26F family with sequence similarity 26, member F
FASLG Fas ligand (TNF superfamily, member 6)
FBXO8 F-box protein 8
FCAR Fc fragment of IgA receptor
FCRLA Fc receptor-like A
FFAR4 free fatty acid receptor 4
FLCN folliculin
FXR2 fragile X mental retardation, autosomal homolog 2
FXYD3 FXYD domain containing ion transport regulator 3
GAB1 GRB2-associated binding protein 1
GAGE10 G antigen 10
GAGE2D G antigen 2D
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GAS7 growth arrest-specific 7
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBP1 guanylate binding protein 1, interferon-inducible
GBP4 guanylate binding protein 4
GK2 glycerol kinase 2
GNPDA2 glucosamine-6-phosphate deaminase 2
GPR141 G protein-coupled receptor 141
GPR149 G protein-coupled receptor 149
GPX5 glutathione peroxidase 5
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM7 glutamate receptor, metabotropic 7
HCG26 HLA complex group 26 (non-protein coding)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCP5 HLA complex P5 (non-protein coding)
HHLA2 HERV-H LTR-associating 2
HIST1H4G histone cluster 1, H4g
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene)
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-H major histocompatibility complex, class I, H (pseudogene)
HLA-L major histocompatibility complex, class I, L (pseudogene)
HMGN5 high mobility group nucleosome binding domain 5
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
ICAM1 intercellular adhesion molecule 1
IFT88 intraflagellar transport 88
IGFBP7 insulin-like growth factor binding protein 7
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL26 interleukin 26
IL32 interleukin 32
IL4I1 interleukin 4 induced 1
INPP5J inositol polyphosphate-5-phosphatase J
INSM2 insulinoma-associated 2
IQCF6 IQ motif containing F6
IQGAP2 IQ motif containing GTPase activating protein 2
ITGAD integrin, alpha D
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNIP4 Kv channel interacting protein 4
KCTD20 potassium channel tetramerization domain containing 20
KDM1B lysine (K)-specific demethylase 1B
KIAA0408 KIAA0408
KIAA0556 KIAA0556
KIF2B kinesin family member 2B
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KNOP1 lysine-rich nucleolar protein 1
KRTAP27-1 keratin associated protein 27-1
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LARP7 La ribonucleoprotein domain family, member 7
LGALS13 lectin, galactoside-binding, soluble, 13
LGALS14 lectin, galactoside-binding, soluble, 14
LINC00339 long intergenic non-protein coding RNA 339
LOC100130093 uncharacterized LOC100130093
LOC100131691
LOC146481
LOC153910 uncharacterized LOC153910
LOC440461 Rho GTPase activating protein 27 pseudogene
LOC93622 Morf4 family associated protein 1-like 1 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEE1 melanoma antigen family E1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP2K4 mitogen-activated protein kinase kinase 4
MBNL2 muscleblind-like splicing regulator 2
METTL14 methyltransferase like 14
METTL4 methyltransferase like 4
MGP matrix Gla protein
MID2 midline 2
MIS12 MIS12 kinetochore complex component
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MRAS muscle RAS oncogene homolog
MTMR6 myotubularin related protein 6
NAIP NLR family, apoptosis inhibitory protein
NAMPT nicotinamide phosphoribosyltransferase
NBR1 neighbor of BRCA1 gene 1
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NLRC4 NLR family, CARD domain containing 4
NLRP11 NLR family, pyrin domain containing 11
NLRP4 NLR family, pyrin domain containing 4
NOX4 NADPH oxidase 4
NPAS3 neuronal PAS domain protein 3
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSF N-ethylmaleimide-sensitive factor
NUB1 negative regulator of ubiquitin-like proteins 1
NXPE1 neurexophilin and PC-esterase domain family, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OCIAD1 OCIA domain containing 1
OPN5 opsin 5
OPRL1 opiate receptor-like 1
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR11G2 olfactory receptor, family 11, subfamily G, member 2
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR2A12 olfactory receptor, family 2, subfamily A, member 12
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR4C13 olfactory receptor, family 4, subfamily C, member 13
OR4D9 olfactory receptor, family 4, subfamily D, member 9
OR51M1 olfactory receptor, family 51, subfamily M, member 1
OR51V1 olfactory receptor, family 51, subfamily V, member 1
OR56A4 olfactory receptor, family 56, subfamily A, member 4
OR6K6 olfactory receptor, family 6, subfamily K, member 6
OR8B4 olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene)
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PARK2 parkin RBR E3 ubiquitin protein ligase
PCDHA3 protocadherin alpha 3
PCDHA6 protocadherin alpha 6
PCDHA7 protocadherin alpha 7
PCDHGB2 protocadherin gamma subfamily B, 2
PDE1A phosphodiesterase 1A, calmodulin-dependent
PEX12 peroxisomal biogenesis factor 12
PHACTR2 phosphatase and actin regulator 2
PIH1D3 PIH1 domain containing 3
PLA2G12A phospholipase A2, group XIIA
PLA2G1B phospholipase A2, group IB (pancreas)
PLP1 proteolipid protein 1
PRG3 proteoglycan 3
PRKG2 protein kinase, cGMP-dependent, type II
PRMT9 protein arginine methyltransferase 9
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTCHD4 patched domain containing 4
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRM protein tyrosine phosphatase, receptor type, M
RAB12 RAB12, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB41 RAB41, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RCVRN recoverin
RESP18 regulated endocrine-specific protein 18
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHOT1 ras homolog family member T1
RWDD2A RWD domain containing 2A
SAMD9L sterile alpha motif domain containing 9-like
SAYSD1 SAYSVFN motif domain containing 1
SCLT1 sodium channel and clathrin linker 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SCOC short coiled-coil protein
SCPEP1 serine carboxypeptidase 1
SDAD1 SDA1 domain containing 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC22A24 solute carrier family 22, member 24
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SLFN12L schlafen family member 12-like
SLFN5 schlafen family member 5
SMYD4 SET and MYND domain containing 4
SNORA80A small nucleolar RNA, H/ACA box 80A
SOD2 superoxide dismutase 2, mitochondrial
SPATA5 spermatogenesis associated 5
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STIM2 stromal interaction molecule 2
STX7 syntaxin 7
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAPBPL TAP binding protein-like
TEX101 testis expressed 101
TFDP3 transcription factor Dp family, member 3
TIFA TRAF-interacting protein with forkhead-associated domain
TLR1 toll-like receptor 1
TMEM128 transmembrane protein 128
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase
TMEM184C transmembrane protein 184C
TMEM199 transmembrane protein 199
TMX4 thioredoxin-related transmembrane protein 4
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPD52L3 tumor protein D52-like 3
TRAFD1 TRAF-type zinc finger domain containing 1
TREML4 triggering receptor expressed on myeloid cells-like 4
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
TRIM5 tripartite motif containing 5
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBG2 tubulin, gamma 2
UBD ubiquitin D
UBE2G1 ubiquitin-conjugating enzyme E2G 1
USP38 ubiquitin specific peptidase 38
USP50 ubiquitin specific peptidase 50
UTS2B urotensin 2B
VIPR2 vasoactive intestinal peptide receptor 2
VNN3 vanin 3
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WARS tryptophanyl-tRNA synthetase
WDR17 WD repeat domain 17
WDR19 WD repeat domain 19
WDR7 WD repeat domain 7
WIPF3 WAS/WASL interacting protein family, member 3
WNT8B wingless-type MMTV integration site family, member 8B
ZBTB14 zinc finger and BTB domain containing 14
ZFYVE28 zinc finger, FYVE domain containing 28
ZIM3 zinc finger, imprinted 3
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF329 zinc finger protein 329
ZNF438 zinc finger protein 438
ZNF497 zinc finger protein 497
ZNF613 zinc finger protein 613
ZNF652 zinc finger protein 652
ZNF77 zinc finger protein 77
ZNF788 zinc finger family member 788
ZNF790 zinc finger protein 790
ZNF815P zinc finger protein 815, pseudogene
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1

low expression

Symbol Name
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)