Skin Cutaneous Melanoma_SKCM_TCGA-EE-A180-06A-11R-A21D-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

404 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EE-A180-06A-11R-A21D-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM30 ADAM metallopeptidase domain 30
ADAR adenosine deaminase, RNA-specific
ADCY2 adenylate cyclase 2 (brain)
ADGRE2 adhesion G protein-coupled receptor E2
ADSS adenylosuccinate synthase
AHCTF1 AT hook containing transcription factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALX1 ALX homeobox 1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
API5 apoptosis inhibitor 5
APOM apolipoprotein M
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATF7 activating transcription factor 7
ATF7IP activating transcription factor 7 interacting protein
ATG13 autophagy related 13
ATM ATM serine/threonine kinase
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2
B3GALTL beta 1,3-galactosyltransferase-like
BAG5 BCL2-associated athanogene 5
BRSK2 BR serine/threonine kinase 2
C11ORF49 chromosome 11 open reading frame 49
C12ORF49 chromosome 12 open reading frame 49
C14ORF169 chromosome 14 open reading frame 169
C19ORF44 chromosome 19 open reading frame 44
C1ORF131 chromosome 1 open reading frame 131
C1ORF35 chromosome 1 open reading frame 35
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CADPS Ca++-dependent secretion activator
CAPRIN1 cell cycle associated protein 1
CARD16 caspase recruitment domain family, member 16
CARKD carbohydrate kinase domain containing
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAT catalase
CBLN2 cerebellin 2 precursor
CD81 CD81 molecule
CDC16 cell division cycle 16
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CELF1 CUGBP, Elav-like family member 1
CEP170 centrosomal protein 170kDa
CEP170B centrosomal protein 170B
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD1L chromodomain helicase DNA binding protein 1-like
CHD8 chromodomain helicase DNA binding protein 8
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CIDEB cell death-inducing DFFA-like effector b
CKAP5 cytoskeleton associated protein 5
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COG2 component of oligomeric golgi complex 2
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CYCSP52 cytochrome c, somatic pseudogene 52
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYTH3 cytohesin 3
DAZ1 deleted in azoospermia 1
DAZ2 deleted in azoospermia 2
DAZ3 deleted in azoospermia 3
DCX doublecortin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND5A DENN/MADD domain containing 5A
DESI2 desumoylating isopeptidase 2
DGKH diacylglycerol kinase, eta
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DISC1 disrupted in schizophrenia 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DOCK5 dedicator of cytokinesis 5
DOT1L DOT1-like histone H3K79 methyltransferase
DSTYK dual serine/threonine and tyrosine protein kinase
DTX4 deltex 4, E3 ubiquitin ligase
DUSP16 dual specificity phosphatase 16
DUSP8 dual specificity phosphatase 8
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGLN1 egl-9 family hypoxia-inducible factor 1
ELP4 elongator acetyltransferase complex subunit 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EP400 E1A binding protein p400
EPHA5 EPH receptor A5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPSTI1 epithelial stromal interaction 1 (breast)
ERBB3 erb-b2 receptor tyrosine kinase 3
ESYT1 extended synaptotagmin-like protein 1
ETV3 ets variant 3
ETV5 ets variant 5
EXO1 exonuclease 1
EXOC8 exocyst complex component 8
FAM124A family with sequence similarity 124A
FANCF Fanconi anemia, complementation group F
FBXO25 F-box protein 25
FCRLA Fc receptor-like A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FER fer (fps/fes related) tyrosine kinase
FH fumarate hydratase
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FMN1 formin 1
FOXP2 forkhead box P2
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FXYD3 FXYD domain containing ion transport regulator 3
GAS2L3 growth arrest-specific 2 like 3
GATAD2B GATA zinc finger domain containing 2B
GDAP2 ganglioside induced differentiation associated protein 2
GGPS1 geranylgeranyl diphosphate synthase 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLCCI1 glucocorticoid induced 1
GMFB glia maturation factor, beta
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNPAT glyceronephosphate O-acyltransferase
GON4L gon-4-like (C. elegans)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HEATR1 HEAT repeat containing 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H3D histone cluster 2, H3d
HMBOX1 homeobox containing 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPU-AS1 HNRNPU antisense RNA 1
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOXD12 homeobox D12
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFNW1 interferon, omega 1
ILK integrin-linked kinase
INTS6 integrator complex subunit 6
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
IRX1 iroquois homeobox 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KAT6A K(lysine) acetyltransferase 6A
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCTD15 potassium channel tetramerization domain containing 15
KCTD20 potassium channel tetramerization domain containing 20
KDM5D lysine (K)-specific demethylase 5D
KIAA0355 KIAA0355
KIAA0430 KIAA0430
KIAA0754 KIAA0754
KIAA1549L KIAA1549-like
KIAA1715 KIAA1715
KIF26B kinesin family member 26B
KLC1 kinesin light chain 1
KLF14 Kruppel-like factor 14
KRTAP6-3 keratin associated protein 6-3
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LGALS8 lectin, galactoside-binding, soluble, 8
LIMA1 LIM domain and actin binding 1
LIMD1 LIM domains containing 1
LNX2 ligand of numb-protein X 2
LOC388692 uncharacterized LOC388692
LOC613037 nuclear pore complex interacting protein pseudogene
LOC729603 calcineurin-like EF-hand protein 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LYST lysosomal trafficking regulator
MADD MAP-kinase activating death domain
MAML1 mastermind-like 1 (Drosophila)
MCF2L MCF.2 cell line derived transforming sequence-like
MCOLN3 mucolipin 3
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MIPEP mitochondrial intermediate peptidase
MLXIP MLX interacting protein
MSRB3 methionine sulfoxide reductase B3
MSX2 msh homeobox 2
MTCH2 mitochondrial carrier 2
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MX1 MX dynamin-like GTPase 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO7A myosin VIIA
NAP1L4 nucleosome assembly protein 1-like 4
NAT10 N-acetyltransferase 10 (GCN5-related)
NBPF10 neuroblastoma breakpoint family, member 10
NBPF15 neuroblastoma breakpoint family, member 15
NBPF9 neuroblastoma breakpoint family, member 9
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NOP9 NOP9 nucleolar protein
NOTCH2 notch 2
NSD1 nuclear receptor binding SET domain protein 1
NUP133 nucleoporin 133kDa
NUP98 nucleoporin 98kDa
NUPL1 nucleoporin like 1
NVL nuclear VCP-like
NXF1 nuclear RNA export factor 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
OPN3 opsin 3
OR10H2 olfactory receptor, family 10, subfamily H, member 2
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR4F5 olfactory receptor, family 4, subfamily F, member 5
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR5K2 olfactory receptor, family 5, subfamily K, member 2
OR8B2 olfactory receptor, family 8, subfamily B, member 2
PAN3 PAN3 poly(A) specific ribonuclease subunit
PANK3 pantothenate kinase 3
PARVA parvin, alpha
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PAX6 paired box 6
PBRM1 polybromo 1
PCDHA10 protocadherin alpha 10
PCDHA13 protocadherin alpha 13
PCDHA9 protocadherin alpha 9
PCDHB12 protocadherin beta 12
PCDHB13 protocadherin beta 13
PCDHB14 protocadherin beta 14
PCDHB17P protocadherin beta 17 pseudogene
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCDHGB4 protocadherin gamma subfamily B, 4
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE3A phosphodiesterase 3A, cGMP-inhibited
PFN1P2 profilin 1 pseudogene 2
PHRF1 PHD and ring finger domains 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLXNC1 plexin C1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POLG polymerase (DNA directed), gamma
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POMK protein-O-mannose kinase
POMT2 protein-O-mannosyltransferase 2
POU4F1 POU class 4 homeobox 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRDM11 PR domain containing 11
PRKD3 protein kinase D3
PROSER1 proline and serine rich 1
PSEN2 presenilin 2
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRM protein tyrosine phosphatase, receptor type, M
QSER1 glutamine and serine rich 1
RAB4A RAB4A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASA3 RAS p21 protein activator 3
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RB1 retinoblastoma 1
RBM23 RNA binding motif protein 23
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGMB repulsive guidance molecule family member b
RIC8B RIC8 guanine nucleotide exchange factor B
RIMKLB ribosomal modification protein rimK-like family member B
RIT1 Ras-like without CAAX 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF187 ring finger protein 187
RREB1 ras responsive element binding protein 1
RRM1 ribonucleotide reductase M1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RTN4RL1 reticulon 4 receptor-like 1
SALL3 spalt-like transcription factor 3
SAMD4A sterile alpha motif domain containing 4A
SBF2 SET binding factor 2
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SETD5 SET domain containing 5
SETDB2 SET domain, bifurcated 2
SH3BP5L SH3-binding domain protein 5-like
SLAIN1 SLAIN motif family, member 1
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A30 solute carrier family 25, member 30
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLITRK2 SLIT and NTRK-like family, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SMYD3 SET and MYND domain containing 3
SNAP47 synaptosomal-associated protein, 47kDa
SNORA47 small nucleolar RNA, H/ACA box 47
SP1 Sp1 transcription factor
SPHAR S-phase response (cyclin related)
SPRTN SprT-like N-terminal domain
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREBF2 sterol regulatory element binding transcription factor 2
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SSH1 slingshot protein phosphatase 1
ST5 suppression of tumorigenicity 5
ST7-OT3 ST7 overlapping transcript 3
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TAS2R39 taste receptor, type 2, member 39
TATDN2 TatD DNase domain containing 2
TBL1Y transducin (beta)-like 1, Y-linked
TCHP trichoplein, keratin filament binding
TCP11L1 t-complex 11, testis-specific-like 1
TDRD3 tudor domain containing 3
TDRD9 tudor domain containing 9
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TFB2M transcription factor B2, mitochondrial
TFDP1 transcription factor Dp-1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TM9SF2 transmembrane 9 superfamily member 2
TMCO3 transmembrane and coiled-coil domains 3
TMEM132D transmembrane protein 132D
TMEM63A transmembrane protein 63A
TMPPE transmembrane protein with metallophosphoesterase domain
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TP53BP2 tumor protein p53 binding protein 2
TPP1 tripeptidyl peptidase I
TPP2 tripeptidyl peptidase II
TPPP tubulin polymerization promoting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRH thyrotropin-releasing hormone
TRIM11 tripartite motif containing 11
TRIM13 tripartite motif containing 13
TRIM21 tripartite motif containing 21
TRIM34 tripartite motif containing 34
TRIM44 tripartite motif containing 44
TRIM5 tripartite motif containing 5
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM68 tripartite motif containing 68
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSNAX translin-associated factor X
TSSK4 testis-specific serine kinase 4
TTLL5 tubulin tyrosine ligase-like family member 5
TTLL6 tubulin tyrosine ligase-like family member 6
TTTY5 testis-specific transcript, Y-linked 5 (non-protein coding)
TUBGCP3 tubulin, gamma complex associated protein 3
UBXN7 UBX domain protein 7
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UEVLD UEV and lactate/malate dehyrogenase domains
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
USP47 ubiquitin specific peptidase 47
USP9Y ubiquitin specific peptidase 9, Y-linked
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR26 WD repeat domain 26
WDR3 WD repeat domain 3
WDR63 WD repeat domain 63
WSB2 WD repeat and SOCS box containing 2
XPO4 exportin 4
YEATS2 YEATS domain containing 2
YLPM1 YLP motif containing 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBED1 zinc finger, BED-type containing 1
ZBED3 zinc finger, BED-type containing 3
ZBTB37 zinc finger and BTB domain containing 37
ZBTB42 zinc finger and BTB domain containing 42
ZC3H13 zinc finger CCCH-type containing 13
ZC3H4 zinc finger CCCH-type containing 4
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF236 zinc finger protein 236
ZNF317 zinc finger protein 317
ZNF407 zinc finger protein 407
ZNF418 zinc finger protein 418
ZNF445 zinc finger protein 445
ZNF496 zinc finger protein 496
ZNF562 zinc finger protein 562
ZNF618 zinc finger protein 618
ZNF619 zinc finger protein 619
ZNF641 zinc finger protein 641
ZNF669 zinc finger protein 669
ZNF678 zinc finger protein 678
ZNF69 zinc finger protein 69
ZNF697 zinc finger protein 697
ZNF703 zinc finger protein 703
ZNRF4 zinc and ring finger 4
ZSCAN22 zinc finger and SCAN domain containing 22

low expression

Symbol Name
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
UBE2F ubiquitin-conjugating enzyme E2F (putative)