Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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405 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABHD11 abhydrolase domain containing 11
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
AGBL3 ATP/GTP binding protein-like 3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ALG9 ALG9, alpha-1,2-mannosyltransferase
AMBP alpha-1-microglobulin/bikunin precursor
AMELY amelogenin, Y-linked
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae)
ANGPTL3 angiopoietin-like 3
ANKRD7 ankyrin repeat domain 7
ANXA5 annexin A5
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APITD1 apoptosis-inducing, TAF9-like domain 1
APOA1 apolipoprotein A-I
APOC3 apolipoprotein C-III
ARMCX5 armadillo repeat containing, X-linked 5
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASPDH aspartate dehydrogenase domain containing
ASRGL1 asparaginase like 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A1-AS1 ATP1A1 antisense RNA 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAN brevican
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7B B-cell CLL/lymphoma 7B
BDNF-AS BDNF antisense RNA
BMP15 bone morphogenetic protein 15
BMP8B bone morphogenetic protein 8b
BNC2 basonuclin 2
C11ORF31 chromosome 11 open reading frame 31
C11ORF65 chromosome 11 open reading frame 65
C11ORF94 chromosome 11 open reading frame 94
C12ORF57 chromosome 12 open reading frame 57
C14ORF93 chromosome 14 open reading frame 93
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF70 chromosome 2 open reading frame 70
C2ORF73 chromosome 2 open reading frame 73
C5 complement component 5
C6ORF48 chromosome 6 open reading frame 48
C6ORF52 chromosome 6 open reading frame 52
C7ORF49 chromosome 7 open reading frame 49
C7ORF55 chromosome 7 open reading frame 55
C9ORF173 chromosome 9 open reading frame 173
C9ORF40 chromosome 9 open reading frame 40
C9ORF9 chromosome 9 open reading frame 9
CAAP1 caspase activity and apoptosis inhibitor 1
CABIN1 calcineurin binding protein 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBWD1 COBW domain containing 1
CCBL2 cysteine conjugate-beta lyase 2
CCDC114 coiled-coil domain containing 114
CCDC141 coiled-coil domain containing 141
CCDC169 coiled-coil domain containing 169
CCDC176 coiled-coil domain containing 176
CCDC57 coiled-coil domain containing 57
CCNG1 cyclin G1
CDC14B cell division cycle 14B
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDNF cerebral dopamine neurotrophic factor
CELF6 CUGBP, Elav-like family member 6
CEP170P1 centrosomal protein 170kDa pseudogene 1
CEP41 centrosomal protein 41kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CETN3 centrin, EF-hand protein, 3
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHMP3 charged multivesicular body protein 3
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CIPC CLOCK-interacting pacemaker
CLCN5 chloride channel, voltage-sensitive 5
CLRN2 clarin 2
CNGA4 cyclic nucleotide gated channel alpha 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CNPY4 canopy FGF signaling regulator 4
CNTNAP3 contactin associated protein-like 3
COG7 component of oligomeric golgi complex 7
COPG2 coatomer protein complex, subunit gamma 2
CPN1 carboxypeptidase N, polypeptide 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXXC5 CXXC finger protein 5
CYCSP52 cytochrome c, somatic pseudogene 52
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DAPK1 death-associated protein kinase 1
DAZ2 deleted in azoospermia 2
DCPS decapping enzyme, scavenger
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30
DNASE1L1 deoxyribonuclease I-like 1
DNM1P46 dynamin 1 pseudogene 46
DPH5 diphthamide biosynthesis 5
DRAM2 DNA-damage regulated autophagy modulator 2
DTX2 deltex 2, E3 ubiquitin ligase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DUSP12 dual specificity phosphatase 12
EFCAB5 EF-hand calcium binding domain 5
EIF4H eukaryotic translation initiation factor 4H
ELOVL2 ELOVL fatty acid elongase 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERBB3 erb-b2 receptor tyrosine kinase 3
EXOC4 exocyst complex component 4
EXTL1 exostosin-like glycosyltransferase 1
F2 coagulation factor II (thrombin)
F9 coagulation factor IX
FAM185A family with sequence similarity 185, member A
FAM27B family with sequence similarity 27, member B
FAM50B family with sequence similarity 50, member B
FANCD2OS FANCD2 opposite strand
FBXL14 F-box and leucine-rich repeat protein 14
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FGF20 fibroblast growth factor 20
FKBP11 FK506 binding protein 11, 19 kDa
FLJ36777 uncharacterized LOC730971
FLVCR1-AS1 FLVCR1 antisense RNA 1 (head to head)
FOCAD focadhesin
FOXB1 forkhead box B1
FOXO4 forkhead box O4
FOXP4 forkhead box P4
FUK fucokinase
FZD9 frizzled class receptor 9
G6PC glucose-6-phosphatase, catalytic subunit
G6PC2 glucose-6-phosphatase, catalytic, 2
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GAS5 growth arrest-specific 5 (non-protein coding)
GATSL2 GATS protein-like 2
GCC1 GRIP and coiled-coil domain containing 1
GEMIN8P4 gem (nuclear organelle) associated protein 8 pseudogene 4
GJB1 gap junction protein, beta 1, 32kDa
GLE1 GLE1 RNA export mediator
GLT8D1 glycosyltransferase 8 domain containing 1
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GPR89B G protein-coupled receptor 89B
GSAP gamma-secretase activating protein
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
GTF2B general transcription factor IIB
GTF2I general transcription factor IIi
GTF2IP1 general transcription factor IIi pseudogene 1
GTF2IRD1 GTF2I repeat domain containing 1
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2B GTF2I repeat domain containing 2B
GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1
HADH hydroxyacyl-CoA dehydrogenase
HBE1 hemoglobin, epsilon 1
HEATR3 HEAT repeat containing 3
HFE hemochromatosis
HINT1 histidine triad nucleotide binding protein 1
HIP1 huntingtin interacting protein 1
HOXC11 homeobox C11
HOXD12 homeobox D12
HRG histidine-rich glycoprotein
HSPA2 heat shock 70kDa protein 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IFNA5 interferon, alpha 5
IFT22 intraflagellar transport 22
IGSF3 immunoglobulin superfamily, member 3
IPP intracisternal A particle-promoted polypeptide
ITFG2 integrin alpha FG-GAP repeat containing 2
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
KANK2 KN motif and ankyrin repeat domains 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNK16 potassium channel, two pore domain subfamily K, member 16
KIAA0141 KIAA0141
KIAA0391 KIAA0391
KIF24 kinesin family member 24
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHDC10 kelch domain containing 10
KNG1 kininogen 1
KRBA1 KRAB-A domain containing 1
LCA5L Leber congenital amaurosis 5-like
LDHAL6A lactate dehydrogenase A-like 6A
LHFPL1 lipoma HMGIC fusion partner-like 1
LINC00271 long intergenic non-protein coding RNA 271
LINC00467 long intergenic non-protein coding RNA 467
LMBR1 limb development membrane protein 1
LOC100134868 uncharacterized LOC100134868
LOC646813 DEAH (Asp-Glu-Ala-His) box helicase 9 pseudogene
LOC81691 exonuclease NEF-sp
LOH12CR2 loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
LUZP6 leucine zipper protein 6
MAGED2 melanoma antigen family D2
MAGED4B melanoma antigen family D4B
MAGEL2 melanoma antigen family L2
MBP myelin basic protein
MCAM melanoma cell adhesion molecule
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MED11 mediator complex subunit 11
MED20 mediator complex subunit 20
METTL2B methyltransferase like 2B
MGME1 mitochondrial genome maintenance exonuclease 1
MID2 midline 2
MIDN midnolin
MLANA melan-A
MLN motilin
MPZ myelin protein zero
MRPS33 mitochondrial ribosomal protein S33
MYO10 myosin X
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NCK2 NCK adaptor protein 2
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NIPAL1 NIPA-like domain containing 1
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NSUN5 NOP2/Sun domain family, member 5
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP205 nucleoporin 205kDa
NVL nuclear VCP-like
OLIG1 oligodendrocyte transcription factor 1
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR51B4 olfactory receptor, family 51, subfamily B, member 4
OR51B5 olfactory receptor, family 51, subfamily B, member 5
OR6C4 olfactory receptor, family 6, subfamily C, member 4
ORC5 origin recognition complex, subunit 5
ORM1 orosomucoid 1
PABPC5 poly(A) binding protein, cytoplasmic 5
PATL2 protein associated with topoisomerase II homolog 2 (yeast)
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDH1 protocadherin 1
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA12 protocadherin gamma subfamily A, 12
PCGF2 polycomb group ring finger 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLG plasminogen
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PMS2P5 postmeiotic segregation increased 2 pseudogene 5
PNMAL1 paraneoplastic Ma antigen family-like 1
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
POMZP3 POM121 and ZP3 fusion
POR P450 (cytochrome) oxidoreductase
POT1 protection of telomeres 1
POU3F3 POU class 3 homeobox 3
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R3E protein phosphatase 1, regulatory subunit 3E
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKG2 protein kinase, cGMP-dependent, type II
PSAT1 phosphoserine aminotransferase 1
PTCH1 patched 1
PTDSS2 phosphatidylserine synthase 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RABIF RAB interacting factor
RAD51B RAD51 paralog B
RAI1 retinoic acid induced 1
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
RBM18 RNA binding motif protein 18
RBM48 RNA binding motif protein 48
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REPIN1 replication initiator 1
RFC2 replication factor C (activator 1) 2, 40kDa
RHBDD2 rhomboid domain containing 2
RNF144A ring finger protein 144A
RNF183 ring finger protein 183
RPL23P8 ribosomal protein L23 pseudogene 8
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRAGB Ras-related GTP binding B
RRH retinal pigment epithelium-derived rhodopsin homolog
RTN4RL1 reticulon 4 receptor-like 1
SBDSP1 Shwachman-Bodian-Diamond syndrome pseudogene 1
SCAMP4 secretory carrier membrane protein 4
SCUBE2 signal peptide, CUB domain, EGF-like 2
SECISBP2 SECIS binding protein 2
SEP15 15 kDa selenoprotein
SEPT11 septin 11
SERINC4 serine incorporator 4
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SETD4 SET domain containing 4
SGK223 homolog of rat pragma of Rnd2
SGK494 uncharacterized serine/threonine-protein kinase SgK494
SIAE sialic acid acetylesterase
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRT4 sirtuin 4
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC25A40 solute carrier family 25, member 40
SLC25A47 solute carrier family 25, member 47
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC38A6 solute carrier family 38, member 6
SLC44A3 solute carrier family 44, member 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMIM7 small integral membrane protein 7
SNHG8 small nucleolar RNA host gene 8
SNX19 sorting nexin 19
SPACA5 sperm acrosome associated 5
SPATA45 spermatogenesis associated 45
SPATA9 spermatogenesis associated 9
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPIN2B spindlin family, member 2B
SPRED1 sprouty-related, EVH1 domain containing 1
SRP9 signal recognition particle 9kDa
SRPK2 SRSF protein kinase 2
SSC4D scavenger receptor cysteine rich family, 4 domains
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST7L suppression of tumorigenicity 7 like
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L2 stromal antigen 3-like 2 (pseudogene)
STAG3L3 stromal antigen 3-like 3 (pseudogene)
STON1 stonin 1
SYPL1 synaptophysin-like 1
SYS1-DBNDD2 SYS1-DBNDD2 readthrough (NMD candidate)
TADA2A transcriptional adaptor 2A
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TARBP1 TAR (HIV-1) RNA binding protein 1
TAT tyrosine aminotransferase
TATDN3 TatD DNase domain containing 3
TBL1Y transducin (beta)-like 1, Y-linked
TBL2 transducin (beta)-like 2
TCHP trichoplein, keratin filament binding
TCTEX1D2 Tctex1 domain containing 2
TDRD7 tudor domain containing 7
TES testin LIM domain protein
THEM4 thioesterase superfamily member 4
TIGD6 tigger transposable element derived 6
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TM4SF4 transmembrane 4 L six family member 4
TMCO1 transmembrane and coiled-coil domains 1
TMEM116 transmembrane protein 116
TMEM14C transmembrane protein 14C
TMEM168 transmembrane protein 168
TMEM18 transmembrane protein 18
TMEM187 transmembrane protein 187
TMEM209 transmembrane protein 209
TMEM257 transmembrane protein 257
TMEM27 transmembrane protein 27
TMEM5 transmembrane protein 5
TMEM80 transmembrane protein 80
TMEM98 transmembrane protein 98
TMOD1 tropomodulin 1
TNPO3 transportin 3
TNS2 tensin 2
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOR1AIP1 torsin A interacting protein 1
TPK1 thiamin pyrophosphokinase 1
TPMT thiopurine S-methyltransferase
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSC22D4 TSC22 domain family, member 4
TSHZ1 teashirt zinc finger homeobox 1
TSSK6 testis-specific serine kinase 6
TTC12 tetratricopeptide repeat domain 12
TTPA tocopherol (alpha) transfer protein
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TTYH1 tweety family member 1
TYRO3 TYRO3 protein tyrosine kinase
UBE3C ubiquitin protein ligase E3C
UBN2 ubinuclein 2
UFSP1 UFM1-specific peptidase 1 (non-functional)
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
WASL Wiskott-Aldrich syndrome-like
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR60 WD repeat domain 60
WDR91 WD repeat domain 91
WDR92 WD repeat domain 92
WFDC13 WAP four-disulfide core domain 13
WLS wntless Wnt ligand secretion mediator
YBEY ybeY metallopeptidase (putative)
ZC3HC1 zinc finger, C3HC-type containing 1
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZNF181 zinc finger protein 181
ZNF212 zinc finger protein 212
ZNF398 zinc finger protein 398
ZNF425 zinc finger protein 425
ZNF69 zinc finger protein 69
ZNF746 zinc finger protein 746
ZNF775 zinc finger protein 775
ZNF786 zinc finger protein 786
ZNF843 zinc finger protein 843
ZNF862 zinc finger protein 862
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZSCAN21 zinc finger and SCAN domain containing 21

low expression

Symbol Name
ATG7 autophagy related 7
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa