Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

420 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
ADAT1 adenosine deaminase, tRNA-specific 1
AGA aspartylglucosaminidase
AGBL2 ATP/GTP binding protein-like 2
AKR7A2P1 aldo-keto reductase family 7, member A2 pseudogene 1
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD6 ankyrin repeat domain 6
ANKRD7 ankyrin repeat domain 7
ANLN anillin, actin binding protein
ANXA3 annexin A3
APITD1 apoptosis-inducing, TAF9-like domain 1
APTX aprataxin
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASIC5 acid sensing (proton gated) ion channel family member 5
ATM ATM serine/threonine kinase
BAG5 BCL2-associated athanogene 5
BAIAP2L1 BAI1-associated protein 2-like 1
BBS4 Bardet-Biedl syndrome 4
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL7B B-cell CLL/lymphoma 7B
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRCA1 breast cancer 1, early onset
BRWD1 bromodomain and WD repeat domain containing 1
BTG3 BTG family, member 3
C11ORF74 chromosome 11 open reading frame 74
C15ORF40 chromosome 15 open reading frame 40
C15ORF56 chromosome 15 open reading frame 56
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF112 chromosome 1 open reading frame 112
C1ORF115 chromosome 1 open reading frame 115
C21ORF59 chromosome 21 open reading frame 59
C3ORF30 chromosome 3 open reading frame 30
C5ORF34 chromosome 5 open reading frame 34
C6ORF62 chromosome 6 open reading frame 62
C7ORF49 chromosome 7 open reading frame 49
C9ORF64 chromosome 9 open reading frame 64
CAAP1 caspase activity and apoptosis inhibitor 1
CAGE1 cancer antigen 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBWD5 COBW domain containing 5
CBWD6 COBW domain containing 6
CCDC105 coiled-coil domain containing 105
CCDC171 coiled-coil domain containing 171
CCDC36 coiled-coil domain containing 36
CCNC cyclin C
CCNE2 cyclin E2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD164 CD164 molecule, sialomucin
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDON cell adhesion associated, oncogene regulated
CENPI centromere protein I
CENPU centromere protein U
CEP19 centrosomal protein 19kDa
CEP78 centrosomal protein 78kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHEK1 checkpoint kinase 1
CHM choroideremia (Rab escort protein 1)
CHN2 chimerin 2
CLDN12 claudin 12
COMMD8 COMM domain containing 8
COPB1 coatomer protein complex, subunit beta 1
CPA2 carboxypeptidase A2 (pancreatic)
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CRYM-AS1 CRYM antisense RNA 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTPS2 CTP synthase 2
CTTNBP2 cortactin binding protein 2
CXADR coxsackie virus and adenovirus receptor
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYTH3 cytohesin 3
DAPK1 death-associated protein kinase 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DEFB134 defensin, beta 134
DEK DEK proto-oncogene
DEPDC1 DEP domain containing 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLL3 delta-like 3 (Drosophila)
DONSON downstream neighbor of SON
DSN1 DSN1, MIS12 kinetochore complex component
EGF epidermal growth factor
ELAC1 elaC ribonuclease Z 1
EME1 essential meiotic structure-specific endonuclease 1
ERMP1 endoplasmic reticulum metallopeptidase 1
FAM111B family with sequence similarity 111, member B
FAM118B family with sequence similarity 118, member B
FAM120AOS family with sequence similarity 120A opposite strand
FAM200A family with sequence similarity 200, member A
FAM72A family with sequence similarity 72, member A
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FANCI Fanconi anemia, complementation group I
FASTKD3 FAST kinase domains 3
FAT2 FAT atypical cadherin 2
FAXC failed axon connections homolog (Drosophila)
FBXL4 F-box and leucine-rich repeat protein 4
FBXO18 F-box protein, helicase, 18
FBXO4 F-box protein 4
FIGNL1 fidgetin-like 1
FNBP1L formin binding protein 1-like
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli)
FZD9 frizzled class receptor 9
G6PD glucose-6-phosphate dehydrogenase
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GATAD1 GATA zinc finger domain containing 1
GBAS glioblastoma amplified sequence
GCLM glutamate-cysteine ligase, modifier subunit
GCNT7 glucosaminyl (N-acetyl) transferase family member 7
GDA guanine deaminase
GDI2 GDP dissociation inhibitor 2
GID4 GID complex subunit 4
GK5 glycerol kinase 5 (putative)
GMNN geminin, DNA replication inhibitor
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GOLGA1 golgin A1
GPR62 G protein-coupled receptor 62
GPR89B G protein-coupled receptor 89B
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTPBP4 GTP binding protein 4
GUSB glucuronidase, beta
HAUS1 HAUS augmin-like complex, subunit 1
HAUS2 HAUS augmin-like complex, subunit 2
HAUS6 HAUS augmin-like complex, subunit 6
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HEATR5A HEAT repeat containing 5A
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1T histone cluster 1, H1t
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BN histone cluster 1, H2bn
HIST1H3E histone cluster 1, H3e
HIST1H4I histone cluster 1, H4i
HMGN2 high mobility group nucleosomal binding domain 2
HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOOK1 hook microtubule-tethering protein 1
HYLS1 hydrolethalus syndrome 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IQCC IQ motif containing C
IRF4 interferon regulatory factor 4
IRX3 iroquois homeobox 3
IVNS1ABP influenza virus NS1A binding protein
KATNBL1 katanin p80 subunit B-like 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA0895 KIAA0895
KIAA1107 KIAA1107
KIAA1522 KIAA1522
KIF14 kinesin family member 14
KIF23 kinesin family member 23
KIN Kin17 DNA and RNA binding protein
KLF14 Kruppel-like factor 14
KLHDC9 kelch domain containing 9
KLHL32 kelch-like family member 32
KLHL42 kelch-like family member 42
KNTC1 kinetochore associated 1
KRIT1 KRIT1, ankyrin repeat containing
LAMA1 laminin, alpha 1
LAMP2 lysosomal-associated membrane protein 2
LARP4B La ribonucleoprotein domain family, member 4B
LOC100134368 uncharacterized LOC100134368
LOC728613 programmed cell death 6 pseudogene
LOC729603 calcineurin-like EF-hand protein 1 pseudogene
LOC81691 exonuclease NEF-sp
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC16A leucine rich repeat containing 16A
LRRC43 leucine rich repeat containing 43
MAEA macrophage erythroblast attacher
MAGEB1 melanoma antigen family B1
MAGEB6 melanoma antigen family B6
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPK4 mitogen-activated protein kinase 4
MARC1 mitochondrial amidoxime reducing component 1
MDH1B malate dehydrogenase 1B, NAD (soluble)
MELK maternal embryonic leucine zipper kinase
MEX3C mex-3 RNA binding family member C
MGC16275 uncharacterized protein MGC16275
MGME1 mitochondrial genome maintenance exonuclease 1
MMS22L MMS22-like, DNA repair protein
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOAP1 modulator of apoptosis 1
MRPL39 mitochondrial ribosomal protein L39
MRS2 MRS2 magnesium transporter
MSH5 mutS homolog 5
MTAP methylthioadenosine phosphorylase
MTFMT mitochondrial methionyl-tRNA formyltransferase
MYO19 myosin XIX
MYO5C myosin VC
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAE1 NEDD8 activating enzyme E1 subunit 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NCAPG non-SMC condensin I complex, subunit G
NCAPG2 non-SMC condensin II complex, subunit G2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEK4 NIMA-related kinase 4
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2
NKX2-4 NK2 homeobox 4
NKX3-1 NK3 homeobox 1
NLK nemo-like kinase
NOL4L nucleolar protein 4-like
NOP14-AS1 NOP14 antisense RNA 1
NPAT nuclear protein, ataxia-telangiectasia locus
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5DC1 5'-nucleotidase domain containing 1
NUP205 nucleoporin 205kDa
NUP37 nucleoporin 37kDa
NUP50 nucleoporin 50kDa
NUP54 nucleoporin 54kDa
NUPL2 nucleoporin like 2
OIP5 Opa interacting protein 5
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR10K1 olfactory receptor, family 10, subfamily K, member 1
OR10S1 olfactory receptor, family 10, subfamily S, member 1
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2G2 olfactory receptor, family 2, subfamily G, member 2
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OR6T1 olfactory receptor, family 6, subfamily T, member 1
ORC6 origin recognition complex, subunit 6
OSTM1 osteopetrosis associated transmembrane protein 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALB2 partner and localizer of BRCA2
PARN poly(A)-specific ribonuclease
PATE4 prostate and testis expressed 4
PBOV1 prostate and breast cancer overexpressed 1
PCNA proliferating cell nuclear antigen
PEX1 peroxisomal biogenesis factor 1
PF4 platelet factor 4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHTF1 putative homeodomain transcription factor 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PIH1D2 PIH1 domain containing 2
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLSCR1 phospholipid scramblase 1
PMS2P5 postmeiotic segregation increased 2 pseudogene 5
PPBPP2 pro-platelet basic protein pseudogene 2
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRC1 protein regulator of cytokinesis 1
PRDM13 PR domain containing 13
PRDX4 peroxiredoxin 4
PROKR1 prokineticin receptor 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRR26 proline rich 26
PSIP1 PC4 and SFRS1 interacting protein 1
PSMC3IP PSMC3 interacting protein
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RAB9A RAB9A, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD23B RAD23 homolog B (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBBP7 retinoblastoma binding protein 7
RBBP8 retinoblastoma binding protein 8
RBM17 RNA binding motif protein 17
RBM25 RNA binding motif protein 25
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RCOR1 REST corepressor 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDM1 RAD52 motif containing 1
RFC2 replication factor C (activator 1) 2, 40kDa
RHEB Ras homolog enriched in brain
RIPK4 receptor-interacting serine-threonine kinase 4
RLN1 relaxin 1
RLN2 relaxin 2
RMI1 RecQ mediated genome instability 1
RMI2 RecQ mediated genome instability 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF182 ring finger protein 182
RPA4 replication protein A4, 30kDa
RPL23AP64 ribosomal protein L23a pseudogene 64
RRAGD Ras-related GTP binding D
RRM1 ribonucleotide reductase M1
RWDD2B RWD domain containing 2B
S100PBP S100P binding protein
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCAF4 SR-related CTD-associated factor 4
SCRN1 secernin 1
SDHAF4 succinate dehydrogenase complex assembly factor 4
SEC14L3 SEC14-like 3 (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEPHS1 selenophosphate synthetase 1
SETD6 SET domain containing 6
SFT2D2 SFT2 domain containing 2
SGOL1 shugoshin-like 1 (S. pombe)
SHCBP1 SHC SH2-domain binding protein 1
SHROOM2 shroom family member 2
SIX4 SIX homeobox 4
SLAIN1 SLAIN motif family, member 1
SLBP stem-loop binding protein
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A40 solute carrier family 25, member 40
SLC25A51 solute carrier family 25, member 51
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC43A3 solute carrier family 43, member 3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMC1A structural maintenance of chromosomes 1A
SMCR5 Smith-Magenis syndrome chromosome region, candidate 5 (non-protein coding)
SMIM11 small integral membrane protein 11
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNORA11E small nucleolar RNA, H/ACA box 11E
SNORA29 small nucleolar RNA, H/ACA box 29
SNORA4 small nucleolar RNA, H/ACA box 4
SPA17 sperm autoantigenic protein 17
SPDYE2 speedy/RINGO cell cycle regulator family member E2
SRP54 signal recognition particle 54kDa
SSTR4 somatostatin receptor 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L2 stromal antigen 3-like 2 (pseudogene)
STYX serine/threonine/tyrosine interacting protein
SUMF2 sulfatase modifying factor 2
SUMO3 small ubiquitin-like modifier 3
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SVIP small VCP/p97-interacting protein
SYAP1 synapse associated protein 1
SYNJ1 synaptojanin 1
SZT2 seizure threshold 2 homolog (mouse)
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TBX5 T-box 5
TESK2 testis-specific kinase 2
TIGD4 tigger transposable element derived 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TM4SF18 transmembrane 4 L six family member 18
TMEM128 transmembrane protein 128
TMEM14B transmembrane protein 14B
TMEM170A transmembrane protein 170A
TMEM246 transmembrane protein 246
TMEM248 transmembrane protein 248
TMEM25 transmembrane protein 25
TMEM255A transmembrane protein 255A
TMEM56 transmembrane protein 56
TMPRSS13 transmembrane protease, serine 13
TOX3 TOX high mobility group box family member 3
TPGS2 tubulin polyglutamylase complex subunit 2
TRIM61 tripartite motif containing 61
TRIM62 tripartite motif containing 62
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTC8 tetratricopeptide repeat domain 8
TTK TTK protein kinase
TTLL5 tubulin tyrosine ligase-like family member 5
TUBAL3 tubulin, alpha-like 3
TXNRD1 thioredoxin reductase 1
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBE3C ubiquitin protein ligase E3C
ULK2 unc-51 like autophagy activating kinase 2
USP33 ubiquitin specific peptidase 33
USP45 ubiquitin specific peptidase 45
USP51 ubiquitin specific peptidase 51
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VRK1 vaccinia related kinase 1
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR91 WD repeat domain 91
WRB tryptophan rich basic protein
WRNIP1 Werner helicase interacting protein 1
ZBTB34 zinc finger and BTB domain containing 34
ZC3H14 zinc finger CCCH-type containing 14
ZNF138 zinc finger protein 138
ZNF160 zinc finger protein 160
ZNF236 zinc finger protein 236
ZNF280B zinc finger protein 280B
ZNF287 zinc finger protein 287
ZNF311 zinc finger protein 311
ZNF326 zinc finger protein 326
ZNF347 zinc finger protein 347
ZNF367 zinc finger protein 367
ZNF382 zinc finger protein 382
ZNF470 zinc finger protein 470
ZNF525 zinc finger protein 525
ZNF542P zinc finger protein 542, pseudogene
ZNF544 zinc finger protein 544
ZNF548 zinc finger protein 548
ZNF552 zinc finger protein 552
ZNF567 zinc finger protein 567
ZNF680 zinc finger protein 680
ZNF701 zinc finger protein 701
ZNF717 zinc finger protein 717
ZNF749 zinc finger protein 749
ZNF839 zinc finger protein 839
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase

low expression

Symbol Name
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
EIF4E2 eukaryotic translation initiation factor 4E family member 2
KEAP1 kelch-like ECH-associated protein 1
MAU2 MAU2 sister chromatid cohesion factor