Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y6-01A-21R-A239-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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312 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y6-01A-21R-A239-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACSM2A acyl-CoA synthetase medium-chain family member 2A
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACYP2 acylphosphatase 2, muscle type
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY2 adenylate cyclase 2 (brain)
ADGRA3 adhesion G protein-coupled receptor A3
ADSS adenylosuccinate synthase
AEBP1 AE binding protein 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALAD aminolevulinate dehydratase
AMY2A amylase, alpha 2A (pancreatic)
APLF aprataxin and PNKP like factor
APOC2 apolipoprotein C-II
APOC4 apolipoprotein C-IV
APOE apolipoprotein E
APOO apolipoprotein O
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARMC9 armadillo repeat containing 9
ARSD arylsulfatase D
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ARV1 ARV1 homolog (S. cerevisiae)
ATG4A autophagy related 4A, cysteine peptidase
ATG4B autophagy related 4B, cysteine peptidase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BBS12 Bardet-Biedl syndrome 12
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BHMT betaine--homocysteine S-methyltransferase
BLZF1 basic leucine zipper nuclear factor 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C10ORF107 chromosome 10 open reading frame 107
C1ORF189 chromosome 1 open reading frame 189
C1ORF204 chromosome 1 open reading frame 204
C22ORF39 chromosome 22 open reading frame 39
C22ORF46 chromosome 22 open reading frame 46
C2ORF74 chromosome 2 open reading frame 74
C5ORF49 chromosome 5 open reading frame 49
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CBR1 carbonyl reductase 1
CBR4 carbonyl reductase 4
CBY1 chibby homolog 1 (Drosophila)
CCDC110 coiled-coil domain containing 110
CCNDBP1 cyclin D-type binding-protein 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKL3 cyclin-dependent kinase-like 3
CENPM centromere protein M
CHN2 chimerin 2
CIAO1 cytosolic iron-sulfur assembly component 1
CLCN5 chloride channel, voltage-sensitive 5
CLTCL1 clathrin, heavy chain-like 1
CLUL1 clusterin-like 1 (retinal)
CLYBL citrate lyase beta like
CNGA4 cyclic nucleotide gated channel alpha 4
COA5 cytochrome c oxidase assembly factor 5
COA6 cytochrome c oxidase assembly factor 6
COG2 component of oligomeric golgi complex 2
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COMMD3 COMM domain containing 3
COMT catechol-O-methyltransferase
COPZ2 coatomer protein complex, subunit zeta 2
CYB5R3 cytochrome b5 reductase 3
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DCAF8 DDB1 and CUL4 associated factor 8
DCAKD dephospho-CoA kinase domain containing
DCDC2B doublecortin domain containing 2B
DCST2 DC-STAMP domain containing 2
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
DEFB135 defensin, beta 135
DFNB59 deafness, autosomal recessive 59
DGCR14 DiGeorge syndrome critical region gene 14
DGCR2 DiGeorge syndrome critical region gene 2
DGCR6 DiGeorge syndrome critical region gene 6
DGCR6L DiGeorge syndrome critical region gene 6-like
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIRC2 disrupted in renal carcinoma 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAL4 dynein, axonemal, light chain 4
DPH3 diphthamide biosynthesis 3
DSCR8 Down syndrome critical region 8
DSTYK dual serine/threonine and tyrosine protein kinase
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EFHB EF-hand domain family, member B
ELMOD3 ELMO/CED-12 domain containing 3
ENAM enamelin
ENGASE endo-beta-N-acetylglucosaminidase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ENTHD1 ENTH domain containing 1
EPDR1 ependymin related 1
EPYC epiphycan
ETFDH electron-transferring-flavoprotein dehydrogenase
EXD1 exonuclease 3'-5' domain containing 1
F8 coagulation factor VIII, procoagulant component
FAM109B family with sequence similarity 109, member B
FAM161A family with sequence similarity 161, member A
FAM173B family with sequence similarity 173, member B
FAM180B family with sequence similarity 180, member B
FBXO36 F-box protein 36
FCRLA Fc receptor-like A
FERD3L Fer3-like bHLH transcription factor
FH fumarate hydratase
FMO4 flavin containing monooxygenase 4
GEMIN8 gem (nuclear organelle) associated protein 8
GHRLOS ghrelin opposite strand/antisense RNA
GLT8D1 glycosyltransferase 8 domain containing 1
GNPAT glyceronephosphate O-acyltransferase
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
GPR158 G protein-coupled receptor 158
GPR89A G protein-coupled receptor 89A
GYG2 glycogenin 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HDAC11 histone deacetylase 11
HDAC8 histone deacetylase 8
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIRA histone cell cycle regulator
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSF2BP heat shock transcription factor 2 binding protein
HSPH1 heat shock 105kDa/110kDa protein 1
IBSP integrin-binding sialoprotein
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFT20 intraflagellar transport 20
IGFBP7 insulin-like growth factor binding protein 7
IGSF22 immunoglobulin superfamily, member 22
IL1R1 interleukin 1 receptor, type I
INSM1 insulinoma-associated 1
JOSD1 Josephin domain containing 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA1024 KIAA1024
KIAA1804 mixed lineage kinase 4
KLHDC8B kelch domain containing 8B
KLHL22 kelch-like family member 22
KLHL30 kelch-like family member 30
KLKB1 kallikrein B, plasma (Fletcher factor) 1
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LAS1L LAS1-like (S. cerevisiae)
LCNL1 lipocalin-like 1
LDAH lipid droplet associated hydrolase
LINC00202-1 long intergenic non-protein coding RNA 202-1
LINGO1 leucine rich repeat and Ig domain containing 1
LINS lines homolog (Drosophila)
LOC100129534 small nuclear ribonucleoprotein polypeptide N pseudogene
LOC100129550 uncharacterized LOC100129550
LOC100272217 uncharacterized LOC100272217
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
LSAMP limbic system-associated membrane protein
LYPD6 LY6/PLAUR domain containing 6
LYRM9 LYR motif containing 9
M1AP meiosis 1 associated protein
MAPK10 mitogen-activated protein kinase 10
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCEE methylmalonyl CoA epimerase
MDH1 malate dehydrogenase 1, NAD (soluble)
METTL9 methyltransferase like 9
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MIEF1 mitochondrial elongation factor 1
MPC2 mitochondrial pyruvate carrier 2
MRPL24 mitochondrial ribosomal protein L24
MRPL35 mitochondrial ribosomal protein L35
MRPL40 mitochondrial ribosomal protein L40
MRPS25 mitochondrial ribosomal protein S25
MST1L macrophage stimulating 1-like
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MYCBPAP MYCBP associated protein
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYO5B myosin VB
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAGA N-acetylgalactosaminidase, alpha-
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NES nestin
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NIT2 nitrilase family, member 2
NME5 NME/NM23 family member 5
NOX1 NADPH oxidase 1
NTPCR nucleoside-triphosphatase, cancer-related
OAZ3 ornithine decarboxylase antizyme 3
OR14C36 olfactory receptor, family 14, subfamily C, member 36
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR9G4 olfactory receptor, family 9, subfamily G, member 4
OXCT1 3-oxoacid CoA transferase 1
OXNAD1 oxidoreductase NAD-binding domain containing 1
PAAF1 proteasomal ATPase-associated factor 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDE4DIP phosphodiesterase 4D interacting protein
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF5A PHD finger protein 5A
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y
PLCD4 phospholipase C, delta 4
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMM1 phosphomannomutase 1
PNPLA4 patatin-like phospholipase domain containing 4
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POM121L1P POM121 transmembrane nucleoporin-like 1, pseudogene
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
POU1F1 POU class 1 homeobox 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PRDX1 peroxiredoxin 1
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTPRB protein tyrosine phosphatase, receptor type, B
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAB1A RAB1A, member RAS oncogene family
RAB41 RAB41, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RABIF RAB interacting factor
RANGAP1 Ran GTPase activating protein 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBX1 ring-box 1, E3 ubiquitin protein ligase
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RFT1 RFT1 homolog (S. cerevisiae)
RGS20 regulator of G-protein signaling 20
RHOQ ras homolog family member Q
RMDN2 regulator of microtubule dynamics 2
RNF144A ring finger protein 144A
RPS19BP1 ribosomal protein S19 binding protein 1
RRH retinal pigment epithelium-derived rhodopsin homolog
RS1 retinoschisin 1
RUSC1-AS1 RUSC1 antisense RNA 1
S100A1 S100 calcium binding protein A1
SAMM50 SAMM50 sorting and assembly machinery component
SDF2 stromal cell-derived factor 2
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEPT5 septin 5
SEPW1 selenoprotein W, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD4 SET domain containing 4
SGSM3 small G protein signaling modulator 3
SHISA4 shisa family member 4
SKAP1 src kinase associated phosphoprotein 1
SLC10A5 solute carrier family 10, member 5
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC38A6 solute carrier family 38, member 6
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMDT1 single-pass membrane protein with aspartate-rich tail 1
SMIM11 small integral membrane protein 11
SNAPIN SNAP-associated protein
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX13 SRY (sex determining region Y)-box 13
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPRTN SprT-like N-terminal domain
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STBD1 starch binding domain 1
STKLD1 serine/threonine kinase-like domain containing 1
STRIP2 striatin interacting protein 2
STS steroid sulfatase (microsomal), isozyme S
SYNGR1 synaptogyrin 1
SYT5 synaptotagmin V
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TCTA T-cell leukemia translocation altered
TDRD6 tudor domain containing 6
TEX30 testis expressed 30
THEM4 thioesterase superfamily member 4
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TIPRL TOR signaling pathway regulator
TMCO1 transmembrane and coiled-coil domains 1
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM199 transmembrane protein 199
TMEM203 transmembrane protein 203
TMEM255A transmembrane protein 255A
TMEM5 transmembrane protein 5
TMEM86A transmembrane protein 86A
TMEM9 transmembrane protein 9
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TNRC6B trinucleotide repeat containing 6B
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSNAX translin-associated factor X
TTC13 tetratricopeptide repeat domain 13
TTC23L tetratricopeptide repeat domain 23-like
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA8 tubulin, alpha 8
TUBB8 tubulin, beta 8 class VIII
TUBBP5 tubulin, beta pseudogene 5
UBE2A ubiquitin-conjugating enzyme E2A
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UFD1L ubiquitin fusion degradation 1 like (yeast)
UFSP2 UFM1-specific peptidase 2
UGP2 UDP-glucose pyrophosphorylase 2
URB1-AS1 URB1 antisense RNA 1 (head to head)
VCX variable charge, X-linked
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WDR72 WD repeat domain 72
WDR92 WD repeat domain 92
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YOD1 YOD1 deubiquitinase
ZC3H11A zinc finger CCCH-type containing 11A
ZIC4 Zic family member 4
ZNF630 zinc finger protein 630
ZNF846 zinc finger protein 846
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2