Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24C-01A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

408 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24C-01A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABHD17B abhydrolase domain containing 17B
ABHD6 abhydrolase domain containing 6
ABLIM1 actin binding LIM protein 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAA1 acetyl-CoA acyltransferase 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADGRA3 adhesion G protein-coupled receptor A3
AGBL3 ATP/GTP binding protein-like 3
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AKAP11 A kinase (PRKA) anchor protein 11
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMBRA1 autophagy/beclin-1 regulator 1
AMELX amelogenin, X-linked
AMER2 APC membrane recruitment protein 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANO6 anoctamin 6
ANXA3 annexin A3
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID1B AT rich interactive domain 1B (SWI1-like)
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARSD arylsulfatase D
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATRIP ATR interacting protein
B3GALTL beta 1,3-galactosyltransferase-like
BCDIN3D BCDIN3 domain containing
BCL2 B-cell CLL/lymphoma 2
BST1 bone marrow stromal cell antigen 1
BTD biotinidase
C22ORF29 chromosome 22 open reading frame 29
C22ORF39 chromosome 22 open reading frame 39
CADM2 cell adhesion molecule 2
CADPS2 Ca++-dependent secretion activator 2
CAPN7 calpain 7
CAPRIN1 cell cycle associated protein 1
CC2D2A coiled-coil and C2 domain containing 2A
CCDC122 coiled-coil domain containing 122
CCDC174 coiled-coil domain containing 174
CCDC51 coiled-coil domain containing 51
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD44 CD44 molecule (Indian blood group)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CES2 carboxylesterase 2
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CHMP2B charged multivesicular body protein 2B
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHURC1 churchill domain containing 1
CLASP2 cytoplasmic linker associated protein 2
CLN5 ceroid-lipofuscinosis, neuronal 5
CLUL1 clusterin-like 1 (retinal)
CNTF ciliary neurotrophic factor
CNTN3 contactin 3 (plasmacytoma associated)
COMT catechol-O-methyltransferase
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPNE3 copine III
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNND1 catenin (cadherin-associated protein), delta 1
DCAF7 DDB1 and CUL4 associated factor 7
DCDC2 doublecortin domain containing 2
DCLK1 doublecortin-like kinase 1
DCT dopachrome tautomerase
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DENND5B DENN/MADD domain containing 5B
DENND6A DENN/MADD domain containing 6A
DHRS12 dehydrogenase/reductase (SDR family) member 12
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DNASE1 deoxyribonuclease I
DOK6 docking protein 6
DPP8 dipeptidyl-peptidase 8
DSC1 desmocollin 1
DUSP16 dual specificity phosphatase 16
DYM dymeclin
DYNLRB2 dynein, light chain, roadblock-type 2
EAF1 ELL associated factor 1
ECT2L epithelial cell transforming 2 like
EFCAB5 EF-hand calcium binding domain 5
EIF4E3 eukaryotic translation initiation factor 4E family member 3
ELF1 E74-like factor 1 (ets domain transcription factor)
EMP1 epithelial membrane protein 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC4 excision repair cross-complementation group 4
ERMARD ER membrane-associated RNA degradation
EVC Ellis van Creveld protein
EXD2 exonuclease 3'-5' domain containing 2
EXOG endo/exonuclease (5'-3'), endonuclease G-like
F2R coagulation factor II (thrombin) receptor
FAM120B family with sequence similarity 120B
FAM120C family with sequence similarity 120C
FAM122A family with sequence similarity 122A
FAM126A family with sequence similarity 126, member A
FAM129A family with sequence similarity 129, member A
FAM161B family with sequence similarity 161, member B
FAM179B family with sequence similarity 179, member B
FAM192A family with sequence similarity 192, member A
FAM193A family with sequence similarity 193, member A
FAM208A family with sequence similarity 208, member A
FAM86DP family with sequence similarity 86, member D, pseudogene
FBXL17 F-box and leucine-rich repeat protein 17
FBXL2 F-box and leucine-rich repeat protein 2
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FBXO3 F-box protein 3
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FRMD4B FERM domain containing 4B
FRYL FRY-like
GALC galactosylceramidase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GGACT gamma-glutamylamine cyclotransferase
GID4 GID complex subunit 4
GLRA1 glycine receptor, alpha 1
GMFB glia maturation factor, beta
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPALPP1 GPALPP motifs containing 1
GPR158 G protein-coupled receptor 158
GPR27 G protein-coupled receptor 27
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRAMD2 GRAM domain containing 2
GTF2A1L general transcription factor IIA, 1-like
GTF2H5 general transcription factor IIH, polypeptide 5
GTF2IRD2B GTF2I repeat domain containing 2B
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HACL1 2-hydroxyacyl-CoA lyase 1
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC11 histone deacetylase 11
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HINT3 histidine triad nucleotide binding protein 3
HIRA histone cell cycle regulator
HMGB3P1 high mobility group box 3 pseudogene 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HRNR hornerin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPH1 heat shock 105kDa/110kDa protein 1
ICE2 interactor of little elongation complex ELL subunit 2
IFT88 intraflagellar transport 88
IGSF10 immunoglobulin superfamily, member 10
IL13RA1 interleukin 13 receptor, alpha 1
IL17RB interleukin 17 receptor B
IL17RD interleukin 17 receptor D
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IQCK IQ motif containing K
IQGAP2 IQ motif containing GTPase activating protein 2
IRS2 insulin receptor substrate 2
IRX5 iroquois homeobox 5
KAT6A K(lysine) acetyltransferase 6A
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCTD6 potassium channel tetramerization domain containing 6
KDSR 3-ketodihydrosphingosine reductase
KGFLP2 keratinocyte growth factor-like protein 2
KHDC1 KH homology domain containing 1
KIF3A kinesin family member 3A
KLHDC1 kelch domain containing 1
KLHL42 kelch-like family member 42
KPNA3 karyopherin alpha 3 (importin alpha 4)
KTN1-AS1 KTN1 antisense RNA 1
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LAMP2 lysosomal-associated membrane protein 2
LARGE like-glycosyltransferase
LATS1 large tumor suppressor kinase 1
LCA5 Leber congenital amaurosis 5
LEMD3 LEM domain containing 3
LIAS lipoic acid synthetase
LINC00271 long intergenic non-protein coding RNA 271
LMBRD1 LMBR1 domain containing 1
LNX2 ligand of numb-protein X 2
LOC145837
LPIN2 lipin 2
LSM11 LSM11, U7 small nuclear RNA associated
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MADD MAP-kinase activating death domain
MAN2B2 mannosidase, alpha, class 2B, member 2
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MCTP1 multiple C2 domains, transmembrane 1
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MDN1 MDN1, midasin homolog (yeast)
MED17 mediator complex subunit 17
METTL16 methyltransferase like 16
METTL6 methyltransferase like 6
MFAP3L microfibrillar-associated protein 3-like
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICU2 mitochondrial calcium uptake 2
MID2 midline 2
MIPEP mitochondrial intermediate peptidase
MITF microphthalmia-associated transcription factor
MLH3 mutL homolog 3
MPHOSPH8 M-phase phosphoprotein 8
MRPS25 mitochondrial ribosomal protein S25
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYD88 myeloid differentiation primary response 88
MYO5A myosin VA (heavy chain 12, myoxin)
N4BP1 NEDD4 binding protein 1
NALCN sodium leak channel, non selective
NBPF10 neuroblastoma breakpoint family, member 10
NCOA7 nuclear receptor coactivator 7
NCOR1 nuclear receptor corepressor 1
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NIPAL2 NIPA-like domain containing 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOP14 NOP14 nucleolar protein
NOP9 NOP9 nucleolar protein
NPAS3 neuronal PAS domain protein 3
NPEPPS aminopeptidase puromycin sensitive
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRIP1 nuclear receptor interacting protein 1
NSG1 neuron specific gene family member 1
OCIAD1 OCIA domain containing 1
OR1L1 olfactory receptor, family 1, subfamily L, member 1
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OXSR1 oxidative stress responsive 1
PABPC5 poly(A) binding protein, cytoplasmic 5
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAPD5 PAP associated domain containing 5
PARP4 poly (ADP-ribose) polymerase family, member 4
PCDHA4 protocadherin alpha 4
PCDHGA7 protocadherin gamma subfamily A, 7
PCDHGB5 protocadherin gamma subfamily B, 5
PCDHGB7 protocadherin gamma subfamily B, 7
PCNX pecanex homolog (Drosophila)
PDCD6IP programmed cell death 6 interacting protein
PDE12 phosphodiesterase 12
PDHB pyruvate dehydrogenase (lipoamide) beta
PDPK1 3-phosphoinositide dependent protein kinase 1
PDS5A PDS5 cohesin associated factor A
PEX7 peroxisomal biogenesis factor 7
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PITPNA phosphatidylinositol transfer protein, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLS3 plastin 3
PLXNB1 plexin B1
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6
PPP4R2 protein phosphatase 4, regulatory subunit 2
PRKD1 protein kinase D1
PRMT3 protein arginine methyltransferase 3
PRPF8 pre-mRNA processing factor 8
PRSS41 protease, serine, 41
PRY2 PTPN13-like, Y-linked 2
PTGR2 prostaglandin reductase 2
PXK PX domain containing serine/threonine kinase
QSER1 glutamine and serine rich 1
RAI1 retinoic acid induced 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBM23 RNA binding motif protein 23
RBSN rabenosyn, RAB effector
RFC1 replication factor C (activator 1) 1, 145kDa
RNF141 ring finger protein 141
RNF146 ring finger protein 146
RNF170 ring finger protein 170
RNF219 ring finger protein 219
RNF6 ring finger protein (C3H2C3 type) 6
RPP14 ribonuclease P/MRP 14kDa subunit
RPSA ribosomal protein SA
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RYBP RING1 and YY1 binding protein
SAMD4A sterile alpha motif domain containing 4A
SAP18 Sin3A-associated protein, 18kDa
SAP30L SAP30-like
SASH1 SAM and SH3 domain containing 1
SBF2 SET binding factor 2
SECISBP2 SECIS binding protein 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERINC1 serine incorporator 1
SERP2 stress-associated endoplasmic reticulum protein family member 2
SETDB2 SET domain, bifurcated 2
SHISA5 shisa family member 5
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SLBP stem-loop binding protein
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC17A4 solute carrier family 17, member 4
SLC25A30 solute carrier family 25, member 30
SLC25A38 solute carrier family 25, member 38
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC38A1 solute carrier family 38, member 1
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SLMAP sarcolemma associated protein
SMCO3 single-pass membrane protein with coiled-coil domains 3
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMIM19 small integral membrane protein 19
SMYD4 SET and MYND domain containing 4
SOCS6 suppressor of cytokine signaling 6
SOS2 son of sevenless homolog 2 (Drosophila)
SPAG9 sperm associated antigen 9
SPEF2 sperm flagellar 2
SPG11 spastic paraplegia 11 (autosomal recessive)
SPRED1 sprouty-related, EVH1 domain containing 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SSC5D scavenger receptor cysteine rich family, 5 domains
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STK24 serine/threonine kinase 24
STON1 stonin 1
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX18 syntaxin 18
STX7 syntaxin 7
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT14 synaptotagmin XIV
SYTL2 synaptotagmin-like 2
TADA2B transcriptional adaptor 2B
TAPT1 transmembrane anterior posterior transformation 1
TBC1D14 TBC1 domain family, member 14
TBC1D19 TBC1 domain family, member 19
TBL1Y transducin (beta)-like 1, Y-linked
TBX18 T-box 18
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TEC tec protein tyrosine kinase
THAP10 THAP domain containing 10
THOC7 THO complex 7
TIGAR TP53 induced glycolysis regulatory phosphatase
TLR1 toll-like receptor 1
TLR6 toll-like receptor 6
TM9SF2 transmembrane 9 superfamily member 2
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
TMEM181 transmembrane protein 181
TMEM215 transmembrane protein 215
TMEM231 transmembrane protein 231
TMEM242 transmembrane protein 242
TMEM26 transmembrane protein 26
TMEM260 transmembrane protein 260
TMEM33 transmembrane protein 33
TMEM43 transmembrane protein 43
TMEM5 transmembrane protein 5
TMF1 TATA element modulatory factor 1
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TOM1L2 target of myb1-like 2 (chicken)
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TP53 tumor protein p53
TPCN2 two pore segment channel 2
TRIM13 tripartite motif containing 13
TRIM4 tripartite motif containing 4
TRIM44 tripartite motif containing 44
TRIM61 tripartite motif containing 61
TRIM68 tripartite motif containing 68
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae)
TRMT5 tRNA methyltransferase 5
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSPYL1 TSPY-like 1
TSPYL4 TSPY-like 4
TTC28 tetratricopeptide repeat domain 28
TTLL11 tubulin tyrosine ligase-like family member 11
TTPA tocopherol (alpha) transfer protein
TTTY6 testis-specific transcript, Y-linked 6 (non-protein coding)
TUBGCP3 tubulin, gamma complex associated protein 3
TULP4 tubby like protein 4
TXLNGY taxilin gamma pseudogene, Y-linked
UBA3 ubiquitin-like modifier activating enzyme 3
UBE2K ubiquitin-conjugating enzyme E2K
UBL3 ubiquitin-like 3
UBP1 upstream binding protein 1 (LBP-1a)
UBXN2B UBX domain protein 2B
UEVLD UEV and lactate/malate dehyrogenase domains
ULK2 unc-51 like autophagy activating kinase 2
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
UTRN utrophin
VAMP7 vesicle-associated membrane protein 7
VILL villin-like
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
WDR19 WD repeat domain 19
WDR31 WD repeat domain 31
WDR48 WD repeat domain 48
WDR81 WD repeat domain 81
WISP2 WNT1 inducible signaling pathway protein 2
XPC xeroderma pigmentosum, complementation group C
XPO4 exportin 4
YIPF7 Yip1 domain family, member 7
ZBED9 zinc finger, BED-type containing 9
ZC2HC1B zinc finger, C2HC-type containing 1B
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF106 zinc finger protein 106
ZNF236 zinc finger protein 236
ZNF589 zinc finger protein 589
ZNF717 zinc finger protein 717
ZNF843 zinc finger protein 843
ZSCAN29 zinc finger and SCAN domain containing 29
ZSCAN32 zinc finger and SCAN domain containing 32

low expression

Symbol Name
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1