Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F8-06A-11R-A20F-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

366 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F8-06A-11R-A20F-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAP2 ArfGAP with dual PH domains 2
ADGRE1 adhesion G protein-coupled receptor E1
ADGRE5 adhesion G protein-coupled receptor E5
ADRA2B adrenoceptor alpha 2B
AGFG2 ArfGAP with FG repeats 2
AHCYL2 adenosylhomocysteinase-like 2
AIF1 allograft inflammatory factor 1
AKAP12 A kinase (PRKA) anchor protein 12
AKAP5 A kinase (PRKA) anchor protein 5
ANKRD22 ankyrin repeat domain 22
AOAH acyloxyacyl hydrolase (neutrophil)
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
APOL3 apolipoprotein L, 3
APOL6 apolipoprotein L, 6
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASCL2 achaete-scute family bHLH transcription factor 2
ASMT acetylserotonin O-methyltransferase
ASPHD2 aspartate beta-hydroxylase domain containing 2
ATG3 autophagy related 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP8B4 ATPase, class I, type 8B, member 4
B2M beta-2-microglobulin
BATF basic leucine zipper transcription factor, ATF-like
BATF2 basic leucine zipper transcription factor, ATF-like 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCL7B B-cell CLL/lymphoma 7B
BDNF brain-derived neurotrophic factor
BTNL3 butyrophilin-like 3
C1ORF110 chromosome 1 open reading frame 110
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C5ORF56 chromosome 5 open reading frame 56
CADPS Ca++-dependent secretion activator
CALCOCO2 calcium binding and coiled-coil domain 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CBWD2 COBW domain containing 2
CCDC28A coiled-coil domain containing 28A
CCDC42 coiled-coil domain containing 42
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL5 chemokine (C-C motif) ligand 5
CCL8 chemokine (C-C motif) ligand 8
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD101 CD101 molecule
CD160 CD160 molecule
CD2 CD2 molecule
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD47 CD47 molecule
CD5L CD5 molecule-like
CD7 CD7 molecule
CD72 CD72 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLDN25 claudin 25
CLRN2 clarin 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO2A coronin, actin binding protein, 2A
CPA5 carboxypeptidase A5
CRTAM cytotoxic and regulatory T cell molecule
CST7 cystatin F (leukocystatin)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
CYB5R4 cytochrome b5 reductase 4
CYGB cytoglobin
DAAM2 dishevelled associated activator of morphogenesis 2
DDX26B DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIXDC1 DIX domain containing 1
DOCK10 dedicator of cytokinesis 10
DOK2 docking protein 2, 56kDa
DRAM1 DNA-damage regulated autophagy modulator 1
DRD3 dopamine receptor D3
DTHD1 death domain containing 1
DTX3L deltex 3 like, E3 ubiquitin ligase
DYNLT1 dynein, light chain, Tctex-type 1
DYSF dysferlin
EBI3 Epstein-Barr virus induced 3
EHD1 EH-domain containing 1
EID3 EP300 interacting inhibitor of differentiation 3
EIF4E3 eukaryotic translation initiation factor 4E family member 3
ENHO energy homeostasis associated
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETV7 ets variant 7
FAM179A family with sequence similarity 179, member A
FAM26F family with sequence similarity 26, member F
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCRL3 Fc receptor-like 3
FCRL6 Fc receptor-like 6
FEM1C fem-1 homolog c (C. elegans)
FKBP5 FK506 binding protein 5
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLR2 folate receptor 2 (fetal)
FOXN2 forkhead box N2
FOXR1 forkhead box R1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FREM1 FRAS1 related extracellular matrix 1
FRY furry homolog (Drosophila)
FXYD3 FXYD domain containing ion transport regulator 3
FXYD5 FXYD domain containing ion transport regulator 5
FXYD7 FXYD domain containing ion transport regulator 7
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAREM GRB2 associated, regulator of MAPK1
GBP1 guanylate binding protein 1, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GCH1 GTP cyclohydrolase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIMAP1 GTPase, IMAP family member 1
GIMAP4 GTPase, IMAP family member 4
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GIMAP7 GTPase, IMAP family member 7
GIMAP8 GTPase, IMAP family member 8
GJD3 gap junction protein, delta 3, 31.9kDa
GLIPR1L2 GLI pathogenesis-related 1 like 2
GLIPR2 GLI pathogenesis-related 2
GNLY granulysin
GOLM1 golgi membrane protein 1
GPBAR1 G protein-coupled bile acid receptor 1
GPR171 G protein-coupled receptor 171
GPR32 G protein-coupled receptor 32
GPR65 G protein-coupled receptor 65
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
HAPLN3 hyaluronan and proteoglycan link protein 3
HAR1A highly accelerated region 1A (non-protein coding)
HAVCR2 hepatitis A virus cellular receptor 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HK3 hexokinase 3 (white cell)
HLA-F major histocompatibility complex, class I, F
HNF1A-AS1 HNF1A antisense RNA 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPVC1 human papillomavirus (type 18) E5 central sequence-like 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
ICAM1 intercellular adhesion molecule 1
IFI35 interferon-induced protein 35
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12RB1 interleukin 12 receptor, beta 1
IL15RA interleukin 15 receptor, alpha
IL18RAP interleukin 18 receptor accessory protein
IL27 interleukin 27
IL2RB interleukin 2 receptor, beta
IL31 interleukin 31
INSIG1 insulin induced gene 1
IPCEF1 interaction protein for cytohesin exchange factors 1
IQCF1 IQ motif containing F1
IQCF6 IQ motif containing F6
IRF1 interferon regulatory factor 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPK1 inositol-tetrakisphosphate 1-kinase
JAKMIP1 janus kinase and microtubule interacting protein 1
KALRN kalirin, RhoGEF kinase
KIAA1755 KIAA1755
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLF4 Kruppel-like factor 4 (gut)
KLK1 kallikrein 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LCK LCK proto-oncogene, Src family tyrosine kinase
LDLR low density lipoprotein receptor
LGALS14 lectin, galactoside-binding, soluble, 14
LGALS9 lectin, galactoside-binding, soluble, 9
LHFPL1 lipoma HMGIC fusion partner-like 1
LHX2 LIM homeobox 2
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00032 long intergenic non-protein coding RNA 32
LINC00303 long intergenic non-protein coding RNA 303
LINC00305 long intergenic non-protein coding RNA 305
LRRC25 leucine rich repeat containing 25
LRRK2 leucine-rich repeat kinase 2
LRRN3 leucine rich repeat neuronal 3
LRRTM4 leucine rich repeat transmembrane neuronal 4
LXN latexin
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZL6 lysozyme-like 6
MAG myelin associated glycoprotein
MEFV Mediterranean fever
MFSD6 major facilitator superfamily domain containing 6
MPEG1 macrophage expressed 1
MPO myeloperoxidase
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MS4A7 membrane-spanning 4-domains, subfamily A, member 7
MYADM myeloid-associated differentiation marker
NAGK N-acetylglucosamine kinase
NAIP NLR family, apoptosis inhibitory protein
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NCOA1 nuclear receptor coactivator 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NKG7 natural killer cell granule protein 7
NLRC4 NLR family, CARD domain containing 4
NLRP6 NLR family, pyrin domain containing 6
NMI N-myc (and STAT) interactor
NTN4 netrin 4
NUB1 negative regulator of ubiquitin-like proteins 1
OPRM1 opioid receptor, mu 1
OPTN optineurin
OR6S1 olfactory receptor, family 6, subfamily S, member 1
OR8B12 olfactory receptor, family 8, subfamily B, member 12
OSTF1 osteoclast stimulating factor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PARP11 poly (ADP-ribose) polymerase family, member 11
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP9 poly (ADP-ribose) polymerase family, member 9
PCDHA10 protocadherin alpha 10
PCDHA8 protocadherin alpha 8
PCDHB1 protocadherin beta 1
PCDHB17P protocadherin beta 17 pseudogene
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA4 protocadherin gamma subfamily A, 4
PDCD1 programmed cell death 1
PDE10A phosphodiesterase 10A
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PLA2G2D phospholipase A2, group IID
PLEK pleckstrin
PLSCR4 phospholipid scramblase 4
POMC proopiomelanocortin
POU3F3 POU class 3 homeobox 3
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R21 protein phosphatase 1, regulatory subunit 21
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PQLC3 PQ loop repeat containing 3
PRF1 perforin 1 (pore forming protein)
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PRLH prolactin releasing hormone
PRR5L proline rich 5 like
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTRF polymerase I and transcript release factor
QRFP pyroglutamylated RFamide peptide
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB37 RAB37, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHOA ras homolog family member A
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF213 ring finger protein 213
RTN4RL1 reticulon 4 receptor-like 1
RTP4 receptor (chemosensory) transporter protein 4
SAMD9L sterile alpha motif domain containing 9-like
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCARNA9 small Cajal body-specific RNA 9
SECTM1 secreted and transmembrane 1
SFTA1P surfactant associated 1, pseudogene
SGCE sarcoglycan, epsilon
SH2D1A SH2 domain containing 1A
SH2D2A SH2 domain containing 2A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIRPD signal-regulatory protein delta
SIRPG signal-regulatory protein gamma
SIT1 signaling threshold regulating transmembrane adaptor 1
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA65 small nucleolar RNA, H/ACA box 65
SPTA1 spectrin, alpha, erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STX11 syntaxin 11
SUSD3 sushi domain containing 3
SYTL3 synaptotagmin-like 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBPL TAP binding protein-like
TARP TCR gamma alternate reading frame protein
TBX21 T-box 21
TCP10L2 t-complex 10-like 2
TES testin LIM domain protein
TF transferrin
THEMIS thymocyte selection associated
TIAM1 T-cell lymphoma invasion and metastasis 1
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLR8 toll-like receptor 8
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM140 transmembrane protein 140
TMEM150B transmembrane protein 150B
TMEM171 transmembrane protein 171
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNIP3 TNFAIP3 interacting protein 3
TNNT1 troponin T type 1 (skeletal, slow)
TOX thymocyte selection-associated high mobility group box
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC3L trafficking protein particle complex 3-like
TRIM14 tripartite motif containing 14
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM74 tripartite motif containing 74
UBASH3A ubiquitin associated and SH3 domain containing A
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VAMP5 vesicle-associated membrane protein 5
VSTM2L V-set and transmembrane domain containing 2 like
WARS tryptophanyl-tRNA synthetase
XCL1 chemokine (C motif) ligand 1
XCL2 chemokine (C motif) ligand 2
XCR1 chemokine (C motif) receptor 1
XRN1 5'-3' exoribonuclease 1
ZBED2 zinc finger, BED-type containing 2
ZBTB47 zinc finger and BTB domain containing 47
ZDHHC14 zinc finger, DHHC-type containing 14
ZMYND15 zinc finger, MYND-type containing 15
ZNF267 zinc finger protein 267
ZNF680 zinc finger protein 680

low expression

Symbol Name
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
ZNF263 zinc finger protein 263