Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I1-06A-12R-A18U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

363 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I1-06A-12R-A18U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AEBP1 AE binding protein 1
AFF4 AF4/FMR2 family, member 4
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANK2 ankyrin 2, neuronal
ANKRD17 ankyrin repeat domain 17
ANKRD34B ankyrin repeat domain 34B
ANXA5 annexin A5
APOL1 apolipoprotein L, 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP10 Rho GTPase activating protein 10
ARHGAP31 Rho GTPase activating protein 31
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARL10 ADP-ribosylation factor-like 10
ASPA aspartoacylase
ASXL2 additional sex combs like transcriptional regulator 2
ATF6 activating transcription factor 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP9A ATPase, class II, type 9A
BBX bobby sox homolog (Drosophila)
BHLHE40 basic helix-loop-helix family, member e40
BMPR1B bone morphogenetic protein receptor, type IB
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPTF bromodomain PHD finger transcription factor
BRD7P3 bromodomain containing 7 pseudogene 3
BRWD3 bromodomain and WD repeat domain containing 3
BTN3A2 butyrophilin, subfamily 3, member A2
C1ORF101 chromosome 1 open reading frame 101
C1QL2 complement component 1, q subcomponent-like 2
C1QTNF2 C1q and tumor necrosis factor related protein 2
C4ORF3 chromosome 4 open reading frame 3
C6ORF120 chromosome 6 open reading frame 120
C8ORF48 chromosome 8 open reading frame 48
C9ORF106 chromosome 9 open reading frame 106
C9ORF172 chromosome 9 open reading frame 172
CBX7 chromobox homolog 7
CCR10 chemokine (C-C motif) receptor 10
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CHIC1 cysteine-rich hydrophobic domain 1
CLCN3 chloride channel, voltage-sensitive 3
CLDN23 claudin 23
CLEC5A C-type lectin domain family 5, member A
CLEC6A C-type lectin domain family 6, member A
CLIC2 chloride intracellular channel 2
CLOCK clock circadian regulator
CLTC clathrin, heavy chain (Hc)
CNST consortin, connexin sorting protein
COL11A1 collagen, type XI, alpha 1
COLEC12 collectin sub-family member 12
CPD carboxypeptidase D
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPEB4 cytoplasmic polyadenylation element binding protein 4
CSMD1 CUB and Sushi multiple domains 1
CSNK1A1L casein kinase 1, alpha 1-like
CTSO cathepsin O
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXORF57 chromosome X open reading frame 57
CYB5RL cytochrome b5 reductase-like
CYGB cytoglobin
DCAF6 DDB1 and CUL4 associated factor 6
DDR2 discoidin domain receptor tyrosine kinase 2
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND1B DENN/MADD domain containing 1B
DENND4C DENN/MADD domain containing 4C
DHFRL1 dihydrofolate reductase-like 1
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DIEXF digestive organ expansion factor homolog (zebrafish)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25
DRAM1 DNA-damage regulated autophagy modulator 1
DSCR3 Down syndrome critical region 3
DSG2 desmoglein 2
DST dystonin
DUSP4 dual specificity phosphatase 4
EDARADD EDAR-associated death domain
EGLN1 egl-9 family hypoxia-inducible factor 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EOMES eomesodermin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERICH6 glutamate-rich 6
ERLIN2 ER lipid raft associated 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ETNPPL ethanolamine-phosphate phospho-lyase
EVX2 even-skipped homeobox 2
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
F2R coagulation factor II (thrombin) receptor
FAM129A family with sequence similarity 129, member A
FAM170A family with sequence similarity 170, member A
FAM196B family with sequence similarity 196, member B
FAM20B family with sequence similarity 20, member B
FAM210A family with sequence similarity 210, member A
FBXO28 F-box protein 28
FHDC1 FH2 domain containing 1
FLCN folliculin
FMNL2 formin-like 2
FN1 fibronectin 1
FRMD4B FERM domain containing 4B
FRYL FRY-like
FSCN2 fascin actin-bundling protein 2, retinal
FSTL5 follistatin-like 5
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
FXYD4 FXYD domain containing ion transport regulator 4
GABPB2 GA binding protein transcription factor, beta subunit 2
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR119 G protein-coupled receptor 119
GPX8 glutathione peroxidase 8 (putative)
GSTM1 glutathione S-transferase mu 1
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTM3 glutathione S-transferase mu 3 (brain)
H3F3B H3 histone, family 3B (H3.3B)
H3F3C H3 histone, family 3C
HDX highly divergent homeobox
HK2 hexokinase 2
HMCN1 hemicentin 1
HMHB1 histocompatibility (minor) HB-1
HOXD12 homeobox D12
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IGFBP7 insulin-like growth factor binding protein 7
IGSF1 immunoglobulin superfamily, member 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL6ST interleukin 6 signal transducer
ILDR2 immunoglobulin-like domain containing receptor 2
IQGAP2 IQ motif containing GTPase activating protein 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JADE1 jade family PHD finger 1
JRK Jrk homolog (mouse)
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCTD3 potassium channel tetramerization domain containing 3
KIAA0513 KIAA0513
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
LDLR low density lipoprotein receptor
LHFPL2 lipoma HMGIC fusion partner-like 2
LMLN leishmanolysin-like (metallopeptidase M8 family)
LOC100130093 uncharacterized LOC100130093
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100133920 uncharacterized LOC100133920
LOC440461 Rho GTPase activating protein 27 pseudogene
LONRF1 LON peptidase N-terminal domain and ring finger 1
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRK2 leucine-rich repeat kinase 2
LTBP4 latent transforming growth factor beta binding protein 4
LYST lysosomal trafficking regulator
MAATS1 MYCBP-associated, testis expressed 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAML3 mastermind-like 3 (Drosophila)
MAN2B2 mannosidase, alpha, class 2B, member 2
MANBA mannosidase, beta A, lysosomal
MAP1B microtubule-associated protein 1B
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP7D3 MAP7 domain containing 3
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MBNL2 muscleblind-like splicing regulator 2
MED13 mediator complex subunit 13
MFAP3L microfibrillar-associated protein 3-like
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIA3 melanoma inhibitory activity family, member 3
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MOCS3 molybdenum cofactor synthesis 3
MOSPD2 motile sperm domain containing 2
MTMR4 myotubularin related protein 4
MTMR8 myotubularin related protein 8
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MXRA7 matrix-remodelling associated 7
MYLIP myosin regulatory light chain interacting protein
MYO5B myosin VB
NANOS1 nanos homolog 1 (Drosophila)
NARF nuclear prelamin A recognition factor
NAV1 neuron navigator 1
NCSTN nicastrin
NDNF neuron-derived neurotrophic factor
NEK7 NIMA-related kinase 7
NES nestin
NPC1 Niemann-Pick disease, type C1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRP2 neuropilin 2
NSG1 neuron specific gene family member 1
NTF3 neurotrophin 3
NTNG1 netrin G1
NUPR1 nuclear protein, transcriptional regulator, 1
NXT2 nuclear transport factor 2-like export factor 2
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR2M7 olfactory receptor, family 2, subfamily M, member 7
OR52K2 olfactory receptor, family 52, subfamily K, member 2
OR5B2 olfactory receptor, family 5, subfamily B, member 2
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OR8A1 olfactory receptor, family 8, subfamily A, member 1
OR8G5 olfactory receptor, family 8, subfamily G, member 5
OSBPL10 oxysterol binding protein-like 10
OSTCP1 oligosaccharyltransferase complex subunit pseudogene 1
OTUD4 OTU deubiquitinase 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDHB7 protocadherin beta 7
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA9 protocadherin gamma subfamily A, 9
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1P1 phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L3 polycystic kidney disease 1-like 3
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA1A phospholipase A1 member A
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCL2 phospholipase C-like 2
PLIN2 perilipin 2
PLN phospholamban
PLXND1 plexin D1
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PPARA peroxisome proliferator-activated receptor alpha
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRCD progressive rod-cone degeneration
PROS1 protein S (alpha)
PROX1 prospero homeobox 1
PRR14L proline rich 14-like
PSCA prostate stem cell antigen
PTCHD1 patched domain containing 1
PTH2 parathyroid hormone 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRM protein tyrosine phosphatase, receptor type, M
PURA purine-rich element binding protein A
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBSN rabenosyn, RAB effector
RFC1 replication factor C (activator 1) 1, 145kDa
RIOK3 RIO kinase 3
RLIM ring finger protein, LIM domain interacting
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF114 ring finger protein 114
RNF182 ring finger protein 182
RNF43 ring finger protein 43
RNMT RNA (guanine-7-) methyltransferase
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
RXRG retinoid X receptor, gamma
SBF1P1 SET binding factor 1 pseudogene 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SEC24B SEC24 family member B
SEC31A SEC31 homolog A (S. cerevisiae)
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SETD7 SET domain containing (lysine methyltransferase) 7
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGMS2 sphingomyelin synthase 2
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
SHROOM3 shroom family member 3
SIAH1 siah E3 ubiquitin protein ligase 1
SKIL SKI-like proto-oncogene
SLAIN2 SLAIN motif family, member 2
SLC25A43 solute carrier family 25, member 43
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLFN11 schlafen family member 11
SLFN5 schlafen family member 5
SLIT1 slit homolog 1 (Drosophila)
SMG5 SMG5 nonsense mediated mRNA decay factor
SNORA16B small nucleolar RNA, H/ACA box 16B
SNX25 sorting nexin 25
SNX27 sorting nexin family member 27
SORBS2 sorbin and SH3 domain containing 2
SOWAHC sosondowah ankyrin repeat domain family member C
SOX13 SRY (sex determining region Y)-box 13
SPARCL1 SPARC-like 1 (hevin)
SPIRE1 spire-type actin nucleation factor 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAU1 staufen double-stranded RNA binding protein 1
STBD1 starch binding domain 1
STK32A serine/threonine kinase 32A
SYN3 synapsin III
TAAR6 trace amine associated receptor 6
TADA2B transcriptional adaptor 2B
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D19 TBC1 domain family, member 19
TBC1D25 TBC1 domain family, member 25
TBC1D3H TBC1 domain family, member 3H
TBCK TBC1 domain containing kinase
TET2 tet methylcytosine dioxygenase 2
TF transferrin
THBS2 thrombospondin 2
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR1 toll-like receptor 1
TLR3 toll-like receptor 3
TLR6 toll-like receptor 6
TMEM189 transmembrane protein 189
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM27 transmembrane protein 27
TNC tenascin C
TNNI3K TNNI3 interacting kinase
TNRC6C trinucleotide repeat containing 6C
TOR1AIP1 torsin A interacting protein 1
TPR translocated promoter region, nuclear basket protein
TRAM1L1 translocation associated membrane protein 1-like 1
TRIM47 tripartite motif containing 47
TRIM56 tripartite motif containing 56
TSG1 tumor suppressor TSG1
TSSK6 testis-specific serine kinase 6
TTC36 tetratricopeptide repeat domain 36
TTR transthyretin
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBQLN2 ubiquilin 2
UBQLN3 ubiquilin 3
UFL1 UFM1-specific ligase 1
UHMK1 U2AF homology motif (UHM) kinase 1
UNK unkempt family zinc finger
VIPR2 vasoactive intestinal peptide receptor 2
VLDLR very low density lipoprotein receptor
WBP2 WW domain binding protein 2
WDFY3 WD repeat and FYVE domain containing 3
WDR37 WD repeat domain 37
WDR7 WD repeat domain 7
WNK3 WNK lysine deficient protein kinase 3
ZBTB10 zinc finger and BTB domain containing 10
ZBTB4 zinc finger and BTB domain containing 4
ZBTB47 zinc finger and BTB domain containing 47
ZCCHC2 zinc finger, CCHC domain containing 2
ZFHX3 zinc finger homeobox 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF396 zinc finger protein 396
ZNF704 zinc finger protein 704
ZNF860 zinc finger protein 860
ZNFX1 zinc finger, NFX1-type containing 1

low expression

Symbol Name
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor