Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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358 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD15 abhydrolase domain containing 15
ABHD6 abhydrolase domain containing 6
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACIN1 apoptotic chromatin condensation inducer 1
ACOT6 acyl-CoA thioesterase 6
ACOXL acyl-CoA oxidase-like
ACTA2 actin, alpha 2, smooth muscle, aorta
ACY3 aminoacylase 3
ADRBK1 adrenergic, beta, receptor kinase 1
ADSSL1 adenylosuccinate synthase like 1
AK7 adenylate kinase 7
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALMS1P Alstrom syndrome 1 pseudogene
ANAPC2 anaphase promoting complex subunit 2
ANKUB1 ankyrin repeat and ubiquitin domain containing 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATL3 atlastin GTPase 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AVL9 AVL9 homolog (S. cerevisiase)
BAD BCL2-associated agonist of cell death
BBS1 Bardet-Biedl syndrome 1
BCL7B B-cell CLL/lymphoma 7B
BHLHE41 basic helix-loop-helix family, member e41
BHMT2 betaine--homocysteine S-methyltransferase 2
BPIFB3 BPI fold containing family B, member 3
C11ORF52 chromosome 11 open reading frame 52
C11ORF80 chromosome 11 open reading frame 80
C11ORF84 chromosome 11 open reading frame 84
C12ORF77 chromosome 12 open reading frame 77
C14ORF169 chromosome 14 open reading frame 169
C15ORF40 chromosome 15 open reading frame 40
C17ORF105 chromosome 17 open reading frame 105
C17ORF107 chromosome 17 open reading frame 107
C1ORF204 chromosome 1 open reading frame 204
C1ORF56 chromosome 1 open reading frame 56
C20ORF173 chromosome 20 open reading frame 173
C2CD3 C2 calcium-dependent domain containing 3
C7ORF50 chromosome 7 open reading frame 50
CARD14 caspase recruitment domain family, member 14
CATIP ciliogenesis associated TTC17 interacting protein
CC2D1B coiled-coil and C2 domain containing 1B
CCDC63 coiled-coil domain containing 63
CCDC87 coiled-coil domain containing 87
CCNK cyclin K
CCS copper chaperone for superoxide dismutase
CDC26 cell division cycle 26
CDH7 cadherin 7, type 2
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEL carboxyl ester lipase
CGB2 chorionic gonadotropin, beta polypeptide 2
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHMP4A charged multivesicular body protein 4A
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN23 claudin 23
CLEC18A C-type lectin domain family 18, member A
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNPY4 canopy FGF signaling regulator 4
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COASY CoA synthase
COG7 component of oligomeric golgi complex 7
COPG1 coatomer protein complex, subunit gamma 1
CORO1B coronin, actin binding protein, 1B
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPNE9 copine family member IX
CTC1 CTS telomere maintenance complex component 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSK cathepsin K
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYSTM1 cysteine-rich transmembrane module containing 1
DALRD3 DALR anticodon binding domain containing 3
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DENND2D DENN/MADD domain containing 2D
DIABLO diablo, IAP-binding mitochondrial protein
DMGDH dimethylglycine dehydrogenase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM1P46 dynamin 1 pseudogene 46
DOK3 docking protein 3
DPEP3 dipeptidase 3
DPP3 dipeptidyl-peptidase 3
DTNA dystrobrevin, alpha
DUSP15 dual specificity phosphatase 15
DVL2 dishevelled segment polarity protein 2
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF4E1B eukaryotic translation initiation factor 4E family member 1B
EMILIN2 elastin microfibril interfacer 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EVC2 Ellis van Creveld syndrome 2
F11R F11 receptor
FADD Fas (TNFRSF6)-associated via death domain
FAM120AOS family with sequence similarity 120A opposite strand
FAM83F family with sequence similarity 83, member F
FAM86C1 family with sequence similarity 86, member C1
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FES FES proto-oncogene, tyrosine kinase
FKBP2 FK506 binding protein 2, 13kDa
FLVCR1-AS1 FLVCR1 antisense RNA 1 (head to head)
FMO4 flavin containing monooxygenase 4
FNTB farnesyltransferase, CAAX box, beta
FTCD formimidoyltransferase cyclodeaminase
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GDPGP1 GDP-D-glucose phosphorylase 1
GFRA4 GDNF family receptor alpha 4
GHRHR growth hormone releasing hormone receptor
GLB1L galactosidase, beta 1-like
GLE1 GLE1 RNA export mediator
GLIS1 GLIS family zinc finger 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPHN gephyrin
GPR137 G protein-coupled receptor 137
GPR45 G protein-coupled receptor 45
GPRC6A G protein-coupled receptor, class C, group 6, member A
GSTP1 glutathione S-transferase pi 1
HCG4 HLA complex group 4 (non-protein coding)
HDAC11 histone deacetylase 11
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIP1R huntingtin interacting protein 1 related
HIST1H2AE histone cluster 1, H2ae
HIST1H2BN histone cluster 1, H2bn
HIST2H2AA3 histone cluster 2, H2aa3
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST2H2BE histone cluster 2, H2be
HLA-G major histocompatibility complex, class I, G
HPCA hippocalcin
HRASLS2 HRAS-like suppressor 2
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
IFNW1 interferon, omega 1
IFT140 intraflagellar transport 140
IGFBPL1 insulin-like growth factor binding protein-like 1
IL10RB interleukin 10 receptor, beta
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
INPPL1 inositol polyphosphate phosphatase-like 1
ISCU iron-sulfur cluster assembly enzyme
KAAG1 kidney associated antigen 1
KDM1A lysine (K)-specific demethylase 1A
KDM2A lysine (K)-specific demethylase 2A
KHDC1 KH homology domain containing 1
KIF1A kinesin family member 1A
KIF6 kinesin family member 6
KLHDC8B kelch domain containing 8B
KLHDC9 kelch domain containing 9
KLHL30 kelch-like family member 30
KREMEN2 kringle containing transmembrane protein 2
KRTAP19-8 keratin associated protein 19-8
LAMA1 laminin, alpha 1
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LCN10 lipocalin 10
LCNL1 lipocalin-like 1
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIMS3-LOC440895 LIMS3-LOC440895 readthrough
LINC00052 long intergenic non-protein coding RNA 52
LINC00467 long intergenic non-protein coding RNA 467
LIPT2 lipoyl(octanoyl) transferase 2 (putative)
LMF1 lipase maturation factor 1
LOC100126784 uncharacterized LOC100126784
LOC100129534 small nuclear ribonucleoprotein polypeptide N pseudogene
LOC441455 makorin ring finger protein 1 pseudogene
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRC48 leucine rich repeat containing 48
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing
LRWD1 leucine-rich repeats and WD repeat domain containing 1
MAGEB6 melanoma antigen family B6
MAP1A microtubule-associated protein 1A
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK4 mitogen-activated protein kinase 4
MARK2 MAP/microtubule affinity-regulating kinase 2
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MEF2B myocyte enhancer factor 2B
MKRN1 makorin ring finger protein 1
MLXIP MLX interacting protein
MORN1 MORN repeat containing 1
MROH8 maestro heat-like repeat family member 8
MRPL46 mitochondrial ribosomal protein L46
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAT16 N-acetyltransferase 16 (GCN5-related, putative)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEURL4 neuralized E3 ubiquitin protein ligase 4
NGRN neugrin, neurite outgrowth associated
NPFFR1 neuropeptide FF receptor 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRP2 neuropilin 2
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8
NUMA1 nuclear mitotic apparatus protein 1
NUP214 nucleoporin 214kDa
OARD1 O-acyl-ADP-ribose deacylase 1
OIT3 oncoprotein induced transcript 3
OLMALINC oligodendrocyte maturation-associated long intergenic non-coding RNA
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR13C3 olfactory receptor, family 13, subfamily C, member 3
OR2C3 olfactory receptor, family 2, subfamily C, member 3
OR4F15 olfactory receptor, family 4, subfamily F, member 15
OTUD7B OTU deubiquitinase 7B
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAAF1 proteasomal ATPase-associated factor 1
PAQR4 progestin and adipoQ receptor family member IV
PC pyruvate carboxylase
PCDHB15 protocadherin beta 15
PCDHGB7 protocadherin gamma subfamily B, 7
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGF placental growth factor
PHF23 PHD finger protein 23
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKD1L1 polycystic kidney disease 1 like 1
PKN3 protein kinase N3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POMT2 protein-O-mannosyltransferase 2
PPME1 protein phosphatase methylesterase 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRDM14 PR domain containing 14
PRDX5 peroxiredoxin 5
PRKCZ protein kinase C, zeta
PRM1 protamine 1
PROP1 PROP paired-like homeobox 1
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
PRSS21 protease, serine, 21 (testisin)
PRSS41 protease, serine, 41
PRSS42 protease, serine, 42
PSCA prostate stem cell antigen
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXK PX domain containing serine/threonine kinase
PYY peptide YY
PYY2 peptide YY, 2 (pseudogene)
RAB5B RAB5B, member RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASGEF1A RasGEF domain family, member 1A
RBM38 RNA binding motif protein 38
RBM4B RNA binding motif protein 4B
RBPMS2 RNA binding protein with multiple splicing 2
RCE1 Ras converting CAAX endopeptidase 1
RDH8 retinol dehydrogenase 8 (all-trans)
RHBDD2 rhomboid domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF19B ring finger protein 19B
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
ROPN1B rhophilin associated tail protein 1B
RPA1 replication protein A1, 70kDa
RPH3AL rabphilin 3A-like (without C2 domains)
RPS2P32 ribosomal protein S2 pseudogene 32
RPS6KL1 ribosomal protein S6 kinase-like 1
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
RUNDC1 RUN domain containing 1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SETD9 SET domain containing 9
SGSM2 small G protein signaling modulator 2
SH3D21 SH3 domain containing 21
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHF Src homology 2 domain containing F
SLC25A35 solute carrier family 25, member 35
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC38A6 solute carrier family 38, member 6
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLIT1 slit homolog 1 (Drosophila)
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMYD1 SET and MYND domain containing 1
SPATA18 spermatogenesis associated 18
SPATA2 spermatogenesis associated 2
SPATA31A1 SPATA31 subfamily A, member 1
SPATA31A3 SPATA31 subfamily A, member 3
SPATA31A5 SPATA31 subfamily A, member 5
SPATA31C1 SPATA31 subfamily C, member 1
SPATS2 spermatogenesis associated, serine-rich 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
SRCIN1 SRC kinase signaling inhibitor 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSH3 slingshot protein phosphatase 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIP1 stress-induced phosphoprotein 1
STOM stomatin
SUMO3 small ubiquitin-like modifier 3
SURF1 surfeit 1
SYCE3 synaptonemal complex central element protein 3
TACC2 transforming, acidic coiled-coil containing protein 2
TBC1D3P1-DHX40P1 TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCP10L t-complex 10-like
TDRKH tudor and KH domain containing
TM4SF18 transmembrane 4 L six family member 18
TMEM107 transmembrane protein 107
TMEM134 transmembrane protein 134
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOR1B torsin family 1, member B (torsin B)
TOR3A torsin family 3, member A
TOX4 TOX high mobility group box family member 4
TP53TG3B TP53 target 3B
TP53TG5 TP53 target 5
TRIM32 tripartite motif containing 32
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPT1 tRNA phosphotransferase 1
TSPAN33 tetraspanin 33
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTYH2 tweety family member 2
TUBBP5 tubulin, beta pseudogene 5
UCMA upper zone of growth plate and cartilage matrix associated
ULK4 unc-51 like kinase 4
UMODL1-AS1 UMODL1 antisense RNA 1
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3A uroplakin 3A
USP29 ubiquitin specific peptidase 29
VEGFB vascular endothelial growth factor B
VENTXP1 VENT homeobox pseudogene 1
VENTXP7 VENT homeobox pseudogene 7
VGF VGF nerve growth factor inducible
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR31 WD repeat domain 31
WSCD1 WSC domain containing 1
ZAR1L zygote arrest 1-like
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H10 zinc finger CCCH-type containing 10
ZFP42 ZFP42 zinc finger protein
ZFYVE1 zinc finger, FYVE domain containing 1
ZFYVE26 zinc finger, FYVE domain containing 26
ZIC4 Zic family member 4
ZNF174 zinc finger protein 174
ZNF263 zinc finger protein 263
ZNF608 zinc finger protein 608
ZNF79 zinc finger protein 79
ZSCAN32 zinc finger and SCAN domain containing 32

low expression

Symbol Name
AMBRA1 autophagy/beclin-1 regulator 1
API5 apoptosis inhibitor 5
LCLAT1 lysocardiolipin acyltransferase 1
MEMO1 mediator of cell motility 1
PHF21A PHD finger protein 21A
TTC17 tetratricopeptide repeat domain 17
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)