Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

413 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACSS1 acyl-CoA synthetase short-chain family member 1
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAM6 ADAM metallopeptidase domain 6 (pseudogene)
ADAMDEC1 ADAM-like, decysin 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRB2 adhesion G protein-coupled receptor B2
ADGRE3 adhesion G protein-coupled receptor E3
AMICA1 adhesion molecule, interacts with CXADR antigen 1
AMPD1 adenosine monophosphate deaminase 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
AOAH acyloxyacyl hydrolase (neutrophil)
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP25 Rho GTPase activating protein 25
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB1 arrestin, beta 1
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATP8B4 ATPase, class I, type 8B, member 4
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
BAALC brain and acute leukemia, cytoplasmic
BAALC-AS2 BAALC antisense RNA 2
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMP7 bone morphogenetic protein 7
BTG2 BTG family, member 2
C10ORF128 chromosome 10 open reading frame 128
C11ORF21 chromosome 11 open reading frame 21
C19ORF35 chromosome 19 open reading frame 35
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C22ORF34 chromosome 22 open reading frame 34
C2ORF16 chromosome 2 open reading frame 16
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
C7 complement component 7
CASS4 Cas scaffolding protein family member 4
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBWD5 COBW domain containing 5
CCDC69 coiled-coil domain containing 69
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL24 chemokine (C-C motif) ligand 24
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCRL2 chemokine (C-C motif) receptor-like 2
CD160 CD160 molecule
CD163L1 CD163 molecule-like 1
CD209 CD209 molecule
CD274 CD274 molecule
CD300C CD300c molecule
CD300LF CD300 molecule-like family member f
CD38 CD38 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD68 CD68 molecule
CD80 CD80 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CD8B CD8b molecule
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CECR1 cat eye syndrome chromosome region, candidate 1
CFAP46 cilia and flagella associated protein 46
CFLAR CASP8 and FADD-like apoptosis regulator
CFP complement factor properdin
CHIT1 chitinase 1 (chitotriosidase)
CHN2 chimerin 2
CHRM1 cholinergic receptor, muscarinic 1
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLC Charcot-Leyden crystal galectin
CLEC10A C-type lectin domain family 10, member A
CLEC4A C-type lectin domain family 4, member A
CLEC4C C-type lectin domain family 4, member C
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CLVS2 clavesin 2
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CNTN4 contactin 4
COL4A4 collagen, type IV, alpha 4
COTL1 coactosin-like F-actin binding protein 1
CP ceruloplasmin (ferroxidase)
CRLS1 cardiolipin synthase 1
CRTAM cytotoxic and regulatory T cell molecule
CRYBA4 crystallin, beta A4
CRYBB3 crystallin, beta B3
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTSH cathepsin H
CTSS cathepsin S
CUX1 cut-like homeobox 1
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CYBB cytochrome b-245, beta polypeptide
CYSLTR1 cysteinyl leukotriene receptor 1
CYTIP cytohesin 1 interacting protein
DCANP1 dendritic cell-associated nuclear protein
DEPTOR DEP domain containing MTOR-interacting protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKFZP779M0652 uncharacterized DKFZp779M0652
DNAH9 dynein, axonemal, heavy chain 9
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta
DNASE1L3 deoxyribonuclease I-like 3
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DPEP2 dipeptidase 2
DPF3 D4, zinc and double PHD fingers, family 3
DTHD1 death domain containing 1
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DUSP26 dual specificity phosphatase 26 (putative)
EN1 engrailed homeobox 1
ENHO energy homeostasis associated
EXOC3L2 exocyst complex component 3-like 2
FAM155B family with sequence similarity 155, member B
FAM157A family with sequence similarity 157, member A
FAM163B family with sequence similarity 163, member B
FAM168A family with sequence similarity 168, member A
FAM170B family with sequence similarity 170, member B
FAM189A1 family with sequence similarity 189, member A1
FAM46C family with sequence similarity 46, member C
FAM49A family with sequence similarity 49, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL16 F-box and leucine-rich repeat protein 16
FBXO2 F-box protein 2
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCRL5 Fc receptor-like 5
FGF1 fibroblast growth factor 1 (acidic)
FGR FGR proto-oncogene, Src family tyrosine kinase
FLJ41941 uncharacterized LOC100192420
FOLR2 folate receptor 2 (fetal)
FOXP3 forkhead box P3
FPR3 formyl peptide receptor 3
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRMD8 FERM domain containing 8
FUCA1 fucosidase, alpha-L- 1, tissue
FXYD4 FXYD domain containing ion transport regulator 4
FZD7 frizzled class receptor 7
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GIMAP8 GTPase, IMAP family member 8
GM2A GM2 ganglioside activator
GPR141 G protein-coupled receptor 141
GPR15 G protein-coupled receptor 15
GRAP2 GRB2-related adaptor protein 2
GRID1 glutamate receptor, ionotropic, delta 1
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GRK5 G protein-coupled receptor kinase 5
HCK HCK proto-oncogene, Src family tyrosine kinase
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCST hematopoietic cell signal transducer
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIP1 huntingtin interacting protein 1
HK1 hexokinase 1
HK3 hexokinase 3 (white cell)
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSH2D hematopoietic SH2 domain containing
ICOS inducible T-cell co-stimulator
IFNA21 interferon, alpha 21
IFNA5 interferon, alpha 5
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNGR1 interferon gamma receptor 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGLON5 IgLON family member 5
IGSF6 immunoglobulin superfamily, member 6
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10RA interleukin 10 receptor, alpha
IL18RAP interleukin 18 receptor accessory protein
IL1R2 interleukin 1 receptor, type II
IL21 interleukin 21
IL3RA interleukin 3 receptor, alpha (low affinity)
IL5RA interleukin 5 receptor, alpha
IPCEF1 interaction protein for cytohesin exchange factors 1
IPO5 importin 5
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA9 integrin, alpha 9
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JCHAIN joining chain of multimeric IgA and IgM
JSRP1 junctional sarcoplasmic reticulum protein 1
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1644 KIAA1644
KIAA2022 KIAA2022
KIF16B kinesin family member 16B
KIF19 kinesin family member 19
KIF26A kinesin family member 26A
KLHL33 kelch-like family member 33
KLHL40 kelch-like family member 40
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LAMP3 lysosomal-associated membrane protein 3
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LDOC1 leucine zipper, down-regulated in cancer 1
LGMN legumain
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LIMD1 LIM domains containing 1
LINC00189 long intergenic non-protein coding RNA 189
LINC00521 long intergenic non-protein coding RNA 521
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100133669 uncharacterized LOC100133669
LOC285847 uncharacterized LOC285847
LOC643923 uncharacterized LOC643923
LRP2 low density lipoprotein receptor-related protein 2
LRRK1 leucine-rich repeat kinase 1
LY75 lymphocyte antigen 75
LY9 lymphocyte antigen 9
LYZ lysozyme
MAGEB4 melanoma antigen family B4
MAGEE1 melanoma antigen family E1
MAML2 mastermind-like 2 (Drosophila)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP2K5 mitogen-activated protein kinase kinase 5
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MAVS mitochondrial antiviral signaling protein
MB21D2 Mab-21 domain containing 2
MEFV Mediterranean fever
MIXL1 Mix paired-like homeobox
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP25 matrix metallopeptidase 25
MPEG1 macrophage expressed 1
MRC1 mannose receptor, C type 1
MRPL42P5 mitochondrial ribosomal protein L42 pseudogene 5
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MYO1A myosin IA
MYO1F myosin IF
NCF1C neutrophil cytosolic factor 1C pseudogene
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKAP1L NCK-associated protein 1-like
NCOA4 nuclear receptor coactivator 4
NFAM1 NFAT activating protein with ITAM motif 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NGB neuroglobin
NLRP6 NLR family, pyrin domain containing 6
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRROS negative regulator of reactive oxygen species
NT5C3A 5'-nucleotidase, cytosolic IIIA
NXPE4 neurexophilin and PC-esterase domain family, member 4
OGDHL oxoglutarate dehydrogenase-like
OLIG2 oligodendrocyte lineage transcription factor 2
OR10G2 olfactory receptor, family 10, subfamily G, member 2
OR2G6 olfactory receptor, family 2, subfamily G, member 6
OTOF otoferlin
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PADI2 peptidyl arginine deiminase, type II
PARP16 poly (ADP-ribose) polymerase family, member 16
PAX2 paired box 2
PCDHA9 protocadherin alpha 9
PCDHAC2 protocadherin alpha subfamily C, 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDX1 pancreatic and duodenal homeobox 1
PEG10 paternally expressed 10
PHOSPHO1 phosphatase, orphan 1
PIAS1 protein inhibitor of activated STAT, 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKD2L1 polycystic kidney disease 2-like 1
PLA2G2D phospholipase A2, group IID
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCL2 phospholipase C-like 2
PLD3 phospholipase D family, member 3
PLEK pleckstrin
PLXNA1 plexin A1
PLXNA2 plexin A2
POU2AF1 POU class 2 associating factor 1
POU5F2 POU domain class 5, transcription factor 2
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PRDM1 PR domain containing 1, with ZNF domain
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCQ protein kinase C, theta
PROKR2 prokineticin receptor 2
PTAFR platelet-activating factor receptor
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRE protein tyrosine phosphatase, receptor type, E
RAD21L1 RAD21-like 1 (S. pombe)
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGEF1B RasGEF domain family, member 1B
RASL10B RAS-like, family 10, member B
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RAX2 retina and anterior neural fold homeobox 2
RBP5 retinol binding protein 5, cellular
RFX7 regulatory factor X, 7
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
RNASE6 ribonuclease, RNase A family, k6
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SCAMP5 secretory carrier membrane protein 5
SCIMP SLP adaptor and CSK interacting membrane protein
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEPP1 selenoprotein P, plasma, 1
SFMBT2 Scm-like with four mbt domains 2
SFRP1 secreted frizzled-related protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A30 solute carrier family 25, member 30
SLC25A53 solute carrier family 25, member 53
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLIT1 slit homolog 1 (Drosophila)
SMAP2 small ArfGAP2
SMIM10L2B small integral membrane protein 10 like 2B
SNORD116-20 small nucleolar RNA, C/D box 116-20
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNRPN small nuclear ribonucleoprotein polypeptide N
SNX1 sorting nexin 1
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
SPON2 spondin 2, extracellular matrix protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM3 serine/arginine repetitive matrix 3
SSTR3 somatostatin receptor 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYN1 synapsin I
SYN2 synapsin II
SYNPO2 synaptopodin 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAGAP T-cell activation RhoGTPase activating protein
TAS1R3 taste receptor, type 1, member 3
TBC1D4 TBC1 domain family, member 4
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TEX43 testis expressed 43
TFRC transferrin receptor
THEMIS2 thymocyte selection associated family member 2
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLE2 transducin-like enhancer of split 2
TLR8 toll-like receptor 8
TLX1 T-cell leukemia homeobox 1
TLX1NB TLX1 neighbor
TMEM150B transmembrane protein 150B
TMEM176B transmembrane protein 176B
TMEM179 transmembrane protein 179
TMEM59L transmembrane protein 59-like
TMLHE trimethyllysine hydroxylase, epsilon
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TPP1 tripeptidyl peptidase I
TRDN triadin
TRIM14 tripartite motif containing 14
TRIM22 tripartite motif containing 22
TRIM5 tripartite motif containing 5
TSKS testis-specific serine kinase substrate
TSPAN32 tetraspanin 32
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1
UNC13A unc-13 homolog A (C. elegans)
VNN1 vanin 1
VNN2 vanin 2
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WDFY4 WDFY family member 4
WDR91 WD repeat domain 91
WIPF1 WAS/WASL interacting protein family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WSCD2 WSC domain containing 2
XCL1 chemokine (C motif) ligand 1
XCL2 chemokine (C motif) ligand 2
ZBP1 Z-DNA binding protein 1
ZCCHC2 zinc finger, CCHC domain containing 2
ZMAT3 zinc finger, matrin-type 3
ZNF106 zinc finger protein 106
ZNF385B zinc finger protein 385B
ZNF479 zinc finger protein 479
ZNF727 zinc finger protein 727
ZNF831 zinc finger protein 831