Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

413 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABHD3 abhydrolase domain containing 3
ACE angiotensin I converting enzyme
ACER2 alkaline ceramidase 2
ACKR3 atypical chemokine receptor 3
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSM4 acyl-CoA synthetase medium-chain family member 4
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRF3 adhesion G protein-coupled receptor F3
ADGRL4 adhesion G protein-coupled receptor L4
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP14 A kinase (PRKA) anchor protein 14
AKAP5 A kinase (PRKA) anchor protein 5
ANKRD32 ankyrin repeat domain 32
ANO5 anoctamin 5
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AOC3 amine oxidase, copper containing 3
APLN apelin
APOL4 apolipoprotein L, 4
APOL6 apolipoprotein L, 6
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARMT1 acidic residue methyltransferase 1
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB18 ankyrin repeat and SOCS box containing 18
ASCC3 activating signal cointegrator 1 complex subunit 3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF3 activating transcription factor 3
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B2M beta-2-microglobulin
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCL6B B-cell CLL/lymphoma 6, member B
BTNL9 butyrophilin-like 9
C1ORF21 chromosome 1 open reading frame 21
C1ORF54 chromosome 1 open reading frame 54
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1QTNF9 C1q and tumor necrosis factor related protein 9
C22ORF31 chromosome 22 open reading frame 31
C2CD4B C2 calcium-dependent domain containing 4B
C4ORF32 chromosome 4 open reading frame 32
C5AR2 complement component 5a receptor 2
C9ORF40 chromosome 9 open reading frame 40
CALCRL calcitonin receptor-like
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CCDC141 coiled-coil domain containing 141
CCDC169 coiled-coil domain containing 169
CCDC172 coiled-coil domain containing 172
CCL25 chemokine (C-C motif) ligand 25
CCL8 chemokine (C-C motif) ligand 8
CCNC cyclin C
CCNE1 cyclin E1
CCNE2 cyclin E2
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD164 CD164 molecule, sialomucin
CD200R1L CD200 receptor 1-like
CD209 CD209 molecule
CD226 CD226 molecule
CD300LD CD300 molecule-like family member d
CD34 CD34 molecule
CD38 CD38 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK15 cyclin-dependent kinase 15
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CENPE centromere protein E, 312kDa
CEP57L1 centrosomal protein 57kDa-like 1
CFAP54 cilia and flagella associated 54
CHSY3 chondroitin sulfate synthase 3
CLEC14A C-type lectin domain family 14, member A
CLEC3B C-type lectin domain family 3, member B
CLEC7A C-type lectin domain family 7, member A
CLEC9A C-type lectin domain family 9, member A
CLIC5 chloride intracellular channel 5
CLSPN claspin
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CNTLN centlein, centrosomal protein
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF36 chromosome X open reading frame 36
CYBB cytochrome b-245, beta polypeptide
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYYR1 cysteine/tyrosine-rich 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEFB132 defensin, beta 132
DENND1B DENN/MADD domain containing 1B
DICER1 dicer 1, ribonuclease type III
DLL4 delta-like 4 (Drosophila)
DMRT3 doublesex and mab-3 related transcription factor 3
DNAAF1 dynein, axonemal, assembly factor 1
DOK2 docking protein 2, 56kDa
DONSON downstream neighbor of SON
DOPEY1 dopey family member 1
DYNLT1 dynein, light chain, Tctex-type 1
EBI3 Epstein-Barr virus induced 3
ECEL1 endothelin converting enzyme-like 1
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EFCAB5 EF-hand calcium binding domain 5
EFS embryonal Fyn-associated substrate
EGFL6 EGF-like-domain, multiple 6
EMCN endomucin
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
EPSTI1 epithelial stromal interaction 1 (breast)
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERICH4 glutamate-rich 4
ESAM endothelial cell adhesion molecule
EXOC2 exocyst complex component 2
FABP4 fatty acid binding protein 4, adipocyte
FAM111B family with sequence similarity 111, member B
FAM162B family with sequence similarity 162, member B
FAM184A family with sequence similarity 184, member A
FAM26F family with sequence similarity 26, member F
FAM49A family with sequence similarity 49, member A
FAT2 FAT atypical cadherin 2
FATE1 fetal and adult testis expressed 1
FBXO30 F-box protein 30
FBXO39 F-box protein 39
FBXO5 F-box protein 5
FCAR Fc fragment of IgA receptor
FEN1 flap structure-specific endonuclease 1
FFAR3 free fatty acid receptor 3
FGF16 fibroblast growth factor 16
FH fumarate hydratase
FILIP1 filamin A interacting protein 1
FKBP15 FK506 binding protein 15, 133kDa
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FRK fyn-related Src family tyrosine kinase
FZD5 frizzled class receptor 5
GALM galactose mutarotase (aldose 1-epimerase)
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GBP1 guanylate binding protein 1, interferon-inducible
GBP4 guanylate binding protein 4
GBP5 guanylate binding protein 5
GCH1 GTP cyclohydrolase 1
GLIPR2 GLI pathogenesis-related 2
GLYAT glycine-N-acyltransferase
GMNN geminin, DNA replication inhibitor
GPBAR1 G protein-coupled bile acid receptor 1
GPR137C G protein-coupled receptor 137C
GPR21 G protein-coupled receptor 21
GPR31 G protein-coupled receptor 31
GPR4 G protein-coupled receptor 4
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSC goosecoid homeobox
GYPA glycophorin A (MNS blood group)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HACD4 3-hydroxyacyl-CoA dehydratase 4
HADH hydroxyacyl-CoA dehydrogenase
HAS1 hyaluronan synthase 1
HBD hemoglobin, delta
HBS1L HBS1-like translational GTPase
HCP5 HLA complex P5 (non-protein coding)
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIATL1 hippocampus abundant transcript-like 1
HIST1H1D histone cluster 1, H1d
HIST1H2BI histone cluster 1, H2bi
HLA-C major histocompatibility complex, class I, C
HMHB1 histocompatibility (minor) HB-1
HSPA2 heat shock 70kDa protein 2
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
ICOS inducible T-cell co-stimulator
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIH1 interferon induced with helicase C domain 1
IFNB1 interferon, beta 1, fibroblast
IGFBPL1 insulin-like growth factor binding protein-like 1
IGSF6 immunoglobulin superfamily, member 6
IL13 interleukin 13
IL18R1 interleukin 18 receptor 1
IL21 interleukin 21
IL27 interleukin 27
IL32 interleukin 32
INCENP inner centromere protein antigens 135/155kDa
INHBB inhibin, beta B
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSR insulin receptor
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD14 potassium channel tetramerization domain containing 14
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF14 kinesin family member 14
KIF19 kinesin family member 19
KIF26B kinesin family member 26B
KPNA5 karyopherin alpha 5 (importin alpha 6)
LACE1 lactation elevated 1
LAG3 lymphocyte-activation gene 3
LAP3 leucine aminopeptidase 3
LATS1 large tumor suppressor kinase 1
LCNL1 lipocalin-like 1
LHFPL1 lipoma HMGIC fusion partner-like 1
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LOC100240734 uncharacterized LOC100240734
LOC284379 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene
LRP11 low density lipoprotein receptor-related protein 11
LRRC39 leucine rich repeat containing 39
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MANEA mannosidase, endo-alpha
MAOB monoamine oxidase B
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MB21D1 Mab-21 domain containing 1
MCM3 minichromosome maintenance complex component 3
MECOM MDS1 and EVI1 complex locus
MED23 mediator complex subunit 23
MEDAG mesenteric estrogen-dependent adipogenesis
MEFV Mediterranean fever
MICB MHC class I polypeptide-related sequence B
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMS22L MMS22-like, DNA repair protein
MOB1A MOB kinase activator 1A
MOV10 Mov10 RISC complex RNA helicase
MPEG1 macrophage expressed 1
MS4A13 membrane-spanning 4-domains, subfamily A, member 13
MS4A7 membrane-spanning 4-domains, subfamily A, member 7
MTO1 mitochondrial tRNA translation optimization 1
MYCT1 myc target 1
N4BP2L1 NEDD4 binding protein 2-like 1
NFIL3 nuclear factor, interleukin 3 regulated
NLRC5 NLR family, CARD domain containing 5
NMI N-myc (and STAT) interactor
NOTCH4 notch 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR2E1 nuclear receptor subfamily 2, group E, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OLFML1 olfactomedin-like 1
OR2J3 olfactory receptor, family 2, subfamily J, member 3
OR6K6 olfactory receptor, family 6, subfamily K, member 6
OSTM1 osteopetrosis associated transmembrane protein 1
OTOF otoferlin
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP11 poly (ADP-ribose) polymerase family, member 11
PARP14 poly (ADP-ribose) polymerase family, member 14
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDGFB platelet-derived growth factor beta polypeptide
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX3 peroxisomal biogenesis factor 3
PHACTR2 phosphatase and actin regulator 2
PHIP pleckstrin homology domain interacting protein
PI16 peptidase inhibitor 16
PLA2G2C phospholipase A2, group IIC
PPARG peroxisome proliferator-activated receptor gamma
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PRDM1 PR domain containing 1, with ZNF domain
PRDM14 PR domain containing 14
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRKCH protein kinase C, eta
PRKX protein kinase, X-linked
PRRC2C proline-rich coiled-coil 2C
PRSS58 protease, serine, 58
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB23 RAB23, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RASGEF1B RasGEF domain family, member 1B
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RGCC regulator of cell cycle
RGS18 regulator of G-protein signaling 18
RGS3 regulator of G-protein signaling 3
RIMBP2 RIMS binding protein 2
RIMS2 regulating synaptic membrane exocytosis 2
RIT1 Ras-like without CAAX 1
RNF186 ring finger protein 186
RNF213 ring finger protein 213
RRM1 ribonucleotide reductase M1
RSAD2 radical S-adenosyl methionine domain containing 2
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTTN rotatin
SAMD3 sterile alpha motif domain containing 3
SAMD9 sterile alpha motif domain containing 9
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAR1B secretion associated, Ras related GTPase 1B
SCARF1 scavenger receptor class F, member 1
SCARNA11 small Cajal body-specific RNA 11
SCLT1 sodium channel and clathrin linker 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDPR serum deprivation response
SEC63 SEC63 homolog (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC25A47 solute carrier family 25, member 47
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLFN11 schlafen family member 11
SLFN12L schlafen family member 12-like
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNX14 sorting nexin 14
SNX3 sorting nexin 3
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SOX17 SRY (sex determining region Y)-box 17
SOX18 SRY (sex determining region Y)-box 18
SP110 SP110 nuclear body protein
SRGN serglycin
SSTR2 somatostatin receptor 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STK39 serine threonine kinase 39
STX11 syntaxin 11
STX12 syntaxin 12
STX17 syntaxin 17
STX6 syntaxin 6
STXBP5 syntaxin binding protein 5 (tomosyn)
SUCNR1 succinate receptor 1
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNJ1 synaptojanin 1
SYTL3 synaptotagmin-like 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBPL TAP binding protein-like
TAS2R39 taste receptor, type 2, member 39
TAS2R60 taste receptor, type 2, member 60
TAS2R7 taste receptor, type 2, member 7
TBX21 T-box 21
TCF19 transcription factor 19
TCF23 transcription factor 23
TDH L-threonine dehydrogenase (pseudogene)
TDRD7 tudor domain containing 7
TEX35 testis expressed 35
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR8 toll-like receptor 8
TM6SF1 transmembrane 6 superfamily member 1
TMEM150B transmembrane protein 150B
TMPO thymopoietin
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNP2 transition protein 2 (during histone to protamine replacement)
TNXB tenascin XB
TOR4A torsin family 4, member A
TPMT thiopurine S-methyltransferase
TPR translocated promoter region, nuclear basket protein
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC13 trafficking protein particle complex 13
TRAPPC3L trafficking protein particle complex 3-like
TRERF1 transcriptional regulating factor 1
TRIM14 tripartite motif containing 14
TRIM31 tripartite motif containing 31
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TROVE2 TROVE domain family, member 2
TSPAN32 tetraspanin 32
TUSC5 tumor suppressor candidate 5
UBD ubiquitin D
UCN3 urocortin 3
UFL1 UFM1-specific ligase 1
ULBP2 UL16 binding protein 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
WDFY1 WD repeat and FYVE domain containing 1
WDR76 WD repeat domain 76
XAF1 XIAP associated factor 1
XCR1 chemokine (C motif) receptor 1
XRN1 5'-3' exoribonuclease 1
YJEFN3 YjeF N-terminal domain containing 3
ZAR1L zygote arrest 1-like
ZBTB24 zinc finger and BTB domain containing 24
ZBTB41 zinc finger and BTB domain containing 41
ZFP36 ZFP36 ring finger protein
ZNF366 zinc finger protein 366
ZUFSP zinc finger with UFM1-specific peptidase domain