Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

426 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAED1 AhpC/TSA antioxidant enzyme domain containing 1
AASDH aminoadipate-semialdehyde dehydrogenase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACBD5 acyl-CoA binding domain containing 5
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACSM4 acyl-CoA synthetase medium-chain family member 4
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
AFF4 AF4/FMR2 family, member 4
AGGF1 angiogenic factor with G patch and FHA domains 1
AGXT2 alanine--glyoxylate aminotransferase 2
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AMACR alpha-methylacyl-CoA racemase
ANK2 ankyrin 2, neuronal
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD44 ankyrin repeat domain 44
ANO5 anoctamin 5
ANO6 anoctamin 6
ANXA2P2 annexin A2 pseudogene 2
ANXA6 annexin A6
AR androgen receptor
ARHGAP19 Rho GTPase activating protein 19
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG10 autophagy related 10
ATP10D ATPase, class V, type 10D
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BMI1 BMI1 proto-oncogene, polycomb ring finger
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRD9 bromodomain containing 9
BRIX1 BRX1, biogenesis of ribosomes
BST1 bone marrow stromal cell antigen 1
C11ORF63 chromosome 11 open reading frame 63
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C5ORF22 chromosome 5 open reading frame 22
C5ORF42 chromosome 5 open reading frame 42
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CANX calnexin
CAPN3 calpain 3, (p94)
CARF calcium responsive transcription factor
CAST calpastatin
CBR1 carbonyl reductase 1
CBY1 chibby homolog 1 (Drosophila)
CCDC125 coiled-coil domain containing 125
CCDC127 coiled-coil domain containing 127
CCL28 chemokine (C-C motif) ligand 28
CCSER2 coiled-coil serine-rich protein 2
CD200R1L CD200 receptor 1-like
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC45 cell division cycle 45
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CDKL5 cyclin-dependent kinase-like 5
CEP135 centrosomal protein 135kDa
CHIC2 cysteine-rich hydrophobic domain 2
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHSY3 chondroitin sulfate synthase 3
CHUK conserved helix-loop-helix ubiquitous kinase
CHURC1 churchill domain containing 1
CLIP1 CAP-GLY domain containing linker protein 1
CLOCK clock circadian regulator
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COMMD8 COMM domain containing 8
CORO2A coronin, actin binding protein, 2A
CPEB4 cytoplasmic polyadenylation element binding protein 4
CREBRF CREB3 regulatory factor
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK1A1 casein kinase 1, alpha 1
CSNK1E casein kinase 1, epsilon
CTTNBP2NL CTTNBP2 N-terminal like
CUTC cutC copper transporter
CXXC5 CXXC finger protein 5
CYB5R4 cytochrome b5 reductase 4
DCTN4 dynactin 4 (p62)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DENND1B DENN/MADD domain containing 1B
DENND4C DENN/MADD domain containing 4C
DENND6A DENN/MADD domain containing 6A
DGKH diacylglycerol kinase, eta
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DMC1 DNA meiotic recombinase 1
DMXL2 Dmx-like 2
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DOPEY1 dopey family member 1
DOPEY2 dopey family member 2
DPP8 dipeptidyl-peptidase 8
DROSHA drosha, ribonuclease type III
DSCR3 Down syndrome critical region 3
DTX4 deltex 4, E3 ubiquitin ligase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDNRB endothelin receptor type B
EFNB3 ephrin-B3
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EMP1 epithelial membrane protein 1
EPDR1 ependymin related 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERCC6L2 excision repair cross-complementation group 6-like 2
ERCC8 excision repair cross-complementation group 8
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETF1 eukaryotic translation termination factor 1
EXOC1 exocyst complex component 1
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EZR ezrin
FAF2 Fas associated factor family member 2
FAM104A family with sequence similarity 104, member A
FAM111A family with sequence similarity 111, member A
FAM157A family with sequence similarity 157, member A
FAM157B family with sequence similarity 157, member B
FAM178A family with sequence similarity 178, member A
FAM20B family with sequence similarity 20, member B
FAM214B family with sequence similarity 214, member B
FAM21A family with sequence similarity 21, member A
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM63B family with sequence similarity 63, member B
FAXC failed axon connections homolog (Drosophila)
FBXL17 F-box and leucine-rich repeat protein 17
FBXL3 F-box and leucine-rich repeat protein 3
FBXL5 F-box and leucine-rich repeat protein 5
FEM1C fem-1 homolog c (C. elegans)
FERMT2 fermitin family member 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FNIP1 folliculin interacting protein 1
FRYL FRY-like
FSD1L fibronectin type III and SPRY domain containing 1-like
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FXYD6 FXYD domain containing ion transport regulator 6
GAS2L3 growth arrest-specific 2 like 3
GLRA1 glycine receptor, alpha 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNPDA2 glucosamine-6-phosphate deaminase 2
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPR63 G protein-coupled receptor 63
GPR89B G protein-coupled receptor 89B
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRK6 G protein-coupled receptor kinase 6
GRPEL2 GrpE-like 2, mitochondrial (E. coli)
HACD1 3-hydroxyacyl-CoA dehydratase 1
HCFC2 host cell factor C2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIC2 hypermethylated in cancer 2
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGXB3 HMG box domain containing 3
HNMT histamine N-methyltransferase
HOMER1 homer scaffolding protein 1
HPS4 Hermansky-Pudlak syndrome 4
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HTT huntingtin
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT81 intraflagellar transport 81
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6R interleukin 6 receptor
INSM1 insulinoma-associated 1
ISL1 ISL LIM homeobox 1
KCTD20 potassium channel tetramerization domain containing 20
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0825 KIAA0825
KIAA1033 KIAA1033
KIAA1191 KIAA1191
KIAA1211 KIAA1211
KIAA1598
KIAA2018 KIAA2018
KIF2A kinesin heavy chain member 2A
KIF5B kinesin family member 5B
KIF6 kinesin family member 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KLHL22 kelch-like family member 22
KLHL9 kelch-like family member 9
KMT2C lysine (K)-specific methyltransferase 2C
KPNA5 karyopherin alpha 5 (importin alpha 6)
LATS2 large tumor suppressor kinase 2
LDOC1L leucine zipper, down-regulated in cancer 1-like
LGALS3 lectin, galactoside-binding, soluble, 3
LIG4 ligase IV, DNA, ATP-dependent
LIMA1 LIM domain and actin binding 1
LINC00207 long intergenic non-protein coding RNA 207
LINC00303 long intergenic non-protein coding RNA 303
LMAN2 lectin, mannose-binding 2
LMBRD1 LMBR1 domain containing 1
LMBRD2 LMBR1 domain containing 2
LMX1B LIM homeobox transcription factor 1, beta
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC388955 PRELI domain-containing protein 1, mitochondrial pseudogene
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene
LOC728554 THO complex 3 pseudogene
LPCAT2 lysophosphatidylcholine acyltransferase 2
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC75A leucine rich repeat containing 75A
LTN1 listerin E3 ubiquitin protein ligase 1
LYRM2 LYR motif containing 2
LYST lysosomal trafficking regulator
LZTR1 leucine-zipper-like transcription regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAML1 mastermind-like 1 (Drosophila)
MANEA mannosidase, endo-alpha
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MBNL2 muscleblind-like splicing regulator 2
MCF2L MCF.2 cell line derived transforming sequence-like
MED10 mediator complex subunit 10
MED13 mediator complex subunit 13
MED15 mediator complex subunit 15
MFSD11 major facilitator superfamily domain containing 11
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICU2 mitochondrial calcium uptake 2
MIPEP mitochondrial intermediate peptidase
MORC3 MORC family CW-type zinc finger 3
MPDZ multiple PDZ domain protein
MRPL39 mitochondrial ribosomal protein L39
MTMR12 myotubularin related protein 12
MTMR6 myotubularin related protein 6
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYO6 myosin VI
NADK2 NAD kinase 2, mitochondrial
NAP1L2 nucleosome assembly protein 1-like 2
NAP1L3 nucleosome assembly protein 1-like 3
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCOA7 nuclear receptor coactivator 7
NIPBL Nipped-B homolog (Drosophila)
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NNT nicotinamide nucleotide transhydrogenase
NOA1 nitric oxide associated 1
NOV nephroblastoma overexpressed
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
NSD1 nuclear receptor binding SET domain protein 1
NUP155 nucleoporin 155kDa
OPTN optineurin
OR10A5 olfactory receptor, family 10, subfamily A, member 5
OR10J5 olfactory receptor, family 10, subfamily J, member 5
OR11L1 olfactory receptor, family 11, subfamily L, member 1
OR5H6 olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene)
OSTM1 osteopetrosis associated transmembrane protein 1
OTUD7B OTU deubiquitinase 7B
OTULIN OTU deubiquitinase with linear linkage specificity
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PANK3 pantothenate kinase 3
PAPD4 PAP associated domain containing 4
PCDHA10 protocadherin alpha 10
PCDHA11 protocadherin alpha 11
PCDHA4 protocadherin alpha 4
PCDHA5 protocadherin alpha 5
PCDHB15 protocadherin beta 15
PCDHB16 protocadherin beta 16
PCDHB2 protocadherin beta 2
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCDHB9 protocadherin beta 9
PCDHGA11 protocadherin gamma subfamily A, 11
PCYOX1L prenylcysteine oxidase 1 like
PDCD6 programmed cell death 6
PDZD8 PDZ domain containing 8
PEA15 phosphoprotein enriched in astrocytes 15
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGM5 phosphoglucomutase 5
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PI4KAP2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PNPLA8 patatin-like phospholipase domain containing 8
POLK polymerase (DNA directed) kappa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POM121L8P POM121 transmembrane nucleoporin-like 8 pseudogene
PPAT phosphoribosyl pyrophosphate amidotransferase
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRDM7 PR domain containing 7
PRELID1 PRELI domain containing 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTEN phosphatase and tensin homolog
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB24 RAB24, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RABL2B RAB, member of RAS oncogene family-like 2B
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAI14 retinoic acid induced 14
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAP2A RAP2A, member of RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RB1 retinoblastoma 1
RBM22 RNA binding motif protein 22
RC3H2 ring finger and CCCH-type domains 2
REEP5 receptor accessory protein 5
RGS14 regulator of G-protein signaling 14
RHOA ras homolog family member A
RICTOR RPTOR independent companion of MTOR, complex 2
RIT1 Ras-like without CAAX 1
RNASE4 ribonuclease, RNase A family, 4
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
RRH retinal pigment epithelium-derived rhodopsin homolog
RUFY1 RUN and FYVE domain containing 1
RUNX1 runt-related transcription factor 1
SAMD8 sterile alpha motif domain containing 8
SCARF2 scavenger receptor class F, member 2
SCFD2 sec1 family domain containing 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHAF4 succinate dehydrogenase complex assembly factor 4
SDHAP3 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
SECISBP2L SECIS binding protein 2-like
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPT5 septin 5
SERINC5 serine incorporator 5
SETX senataxin
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGMS2 sphingomyelin synthase 2
SGPL1 sphingosine-1-phosphate lyase 1
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIMC1 SUMO-interacting motifs containing 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAIN2 SLAIN motif family, member 2
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A46 solute carrier family 25, member 46
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A11 solute carrier family 39, member 11
SLC45A2 solute carrier family 45, member 2
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SLK STE20-like kinase
SMIM14 small integral membrane protein 14
SNAP29 synaptosomal-associated protein, 29kDa
SNX14 sorting nexin 14
SON SON DNA binding protein
SORT1 sortilin 1
SOX13 SRY (sex determining region Y)-box 13
SOX2 SRY (sex determining region Y)-box 2
SPG11 spastic paraplegia 11 (autosomal recessive)
SQSTM1 sequestosome 1
SRD5A3 steroid 5 alpha-reductase 3
SRP72 signal recognition particle 72kDa
SRRD SRR1 domain containing
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STXBP3 syntaxin binding protein 3
SUB1 SUB1 homolog (S. cerevisiae)
SYNJ1 synaptojanin 1
SYT11 synaptotagmin XI
TAOK1 TAO kinase 1
TARS threonyl-tRNA synthetase
TBC1D12 TBC1 domain family, member 12
TBC1D19 TBC1 domain family, member 19
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TFIP11 tuftelin interacting protein 11
THAP7 THAP domain containing 7
THOC3 THO complex 3
TIGD6 tigger transposable element derived 6
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TLR1 toll-like receptor 1
TLR6 toll-like receptor 6
TMED8 transmembrane emp24 protein transport domain containing 8
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM165 transmembrane protein 165
TMEM184B transmembrane protein 184B
TMEM191A transmembrane protein 191A (pseudogene)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TP53BP2 tumor protein p53 binding protein 2
TPBG trophoblast glycoprotein
TRAPPC10 trafficking protein particle complex 10
TRAPPC13 trafficking protein particle complex 13
TRIM37 tripartite motif containing 37
TRIP13 thyroid hormone receptor interactor 13
TSPAN17 tetraspanin 17
TTC3 tetratricopeptide repeat domain 3
TTC33 tetratricopeptide repeat domain 33
TXNRD1 thioredoxin reductase 1
UFL1 UFM1-specific ligase 1
UHMK1 U2AF homology motif (UHM) kinase 1
UIMC1 ubiquitin interaction motif containing 1
ULBP2 UL16 binding protein 2
UNC13B unc-13 homolog B (C. elegans)
UPP1 uridine phosphorylase 1
USP12 ubiquitin specific peptidase 12
USP25 ubiquitin specific peptidase 25
USP32 ubiquitin specific peptidase 32
USP46 ubiquitin specific peptidase 46
VAMP4 vesicle-associated membrane protein 4
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WAPAL wings apart-like homolog (Drosophila)
WDR41 WD repeat domain 41
WDR47 WD repeat domain 47
WDR7 WD repeat domain 7
WDR70 WD repeat domain 70
WISP2 WNT1 inducible signaling pathway protein 2
WSB2 WD repeat and SOCS box containing 2
ZBTB14 zinc finger and BTB domain containing 14
ZBTB41 zinc finger and BTB domain containing 41
ZFR zinc finger RNA binding protein
ZNF25 zinc finger protein 25
ZNF346 zinc finger protein 346
ZNF354B zinc finger protein 354B
ZNF879 zinc finger protein 879