Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Skin Cutaneous Melanoma_SKCM (The Cancer Genome Atlas)
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Genes

388 genes with high or low expression in Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
AARSD1 alanyl-tRNA synthetase domain containing 1
AATK apoptosis-associated tyrosine kinase
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABHD14B abhydrolase domain containing 14B
ABHD15 abhydrolase domain containing 15
ACBD6 acyl-CoA binding domain containing 6
ACOT2 acyl-CoA thioesterase 2
ACOT4 acyl-CoA thioesterase 4
ACTL10 actin-like 10
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAR adenosine deaminase, RNA-specific
ADAT3 adenosine deaminase, tRNA-specific 3
ADCK4 aarF domain containing kinase 4
ADD1 adducin 1 (alpha)
ADGRG1 adhesion G protein-coupled receptor G1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHNAK2 AHNAK nucleoprotein 2
ALG1L ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like
AMT aminomethyltransferase
ANKRD16 ankyrin repeat domain 16
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOC4 apolipoprotein C-IV
APOO apolipoprotein O
AQP6 aquaporin 6, kidney specific
ARF1 ADP-ribosylation factor 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARMS2 age-related maculopathy susceptibility 2
ARV1 ARV1 homolog (S. cerevisiae)
ASCC1 activating signal cointegrator 1 complex subunit 1
ATL1 atlastin GTPase 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN7L3 ataxin 7-like 3
AURKA aurora kinase A
BANF2 barrier to autointegration factor 2
BCAP31 B-cell receptor-associated protein 31
BCYRN1 brain cytoplasmic RNA 1
BEST1 bestrophin 1
BLCAP bladder cancer associated protein
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BOLA1 bolA family member 1
BPIFB1 BPI fold containing family B, member 1
BPIFB2 BPI fold containing family B, member 2
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
C14ORF169 chromosome 14 open reading frame 169
C16ORF86 chromosome 16 open reading frame 86
C17ORF105 chromosome 17 open reading frame 105
C1ORF35 chromosome 1 open reading frame 35
C1ORF43 chromosome 1 open reading frame 43
C2CD4D C2 calcium-dependent domain containing 4D
C2ORF81 chromosome 2 open reading frame 81
C6ORF52 chromosome 6 open reading frame 52
C9ORF24 chromosome 9 open reading frame 24
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAPN2 calpain 2, (m/II) large subunit
CAPN3 calpain 3, (p94)
CCDC106 coiled-coil domain containing 106
CCDC96 coiled-coil domain containing 96
CD9 CD9 molecule
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDKN2AIPNL CDKN2A interacting protein N-terminal like
CDNF cerebral dopamine neurotrophic factor
CENPB centromere protein B, 80kDa
CEP250 centrosomal protein 250kDa
CERS2 ceramide synthase 2
CHMP4B charged multivesicular body protein 4B
CIART circadian associated repressor of transcription
CLDN23 claudin 23
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLRN2 clarin 2
CLYBL citrate lyase beta like
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COG2 component of oligomeric golgi complex 2
COMMD7 COMM domain containing 7
COQ9 coenzyme Q9
CREB3L4 cAMP responsive element binding protein 3-like 4
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTBP1 C-terminal binding protein 1
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBL1 catenin, beta like 1
CTPS2 CTP synthase 2
CXORF38 chromosome X open reading frame 38
CXXC5 CXXC finger protein 5
DDRGK1 DDRGK domain containing 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DEDD death effector domain containing
DEFB119 defensin, beta 119
DEGS1 delta(4)-desaturase, sphingolipid 1
DGKQ diacylglycerol kinase, theta 110kDa
DHODH dihydroorotate dehydrogenase (quinone)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DNASE1L1 deoxyribonuclease I-like 1
DUSP12 dual specificity phosphatase 12
DUSP15 dual specificity phosphatase 15
DUSP23 dual specificity phosphatase 23
DYNLRB1 dynein, light chain, roadblock-type 1
DYNLRB2 dynein, light chain, roadblock-type 2
EFHB EF-hand domain family, member B
EIF6 eukaryotic translation initiation factor 6
EMC6 ER membrane protein complex subunit 6
ENSA endosulfine alpha
EPX eosinophil peroxidase
ESPNL espin-like
ETNK2 ethanolamine kinase 2
EXOSC6 exosome component 6
FAM189B family with sequence similarity 189, member B
FAM193A family with sequence similarity 193, member A
FAM41C family with sequence similarity 41, member C
FAM50B family with sequence similarity 50, member B
FAM53A family with sequence similarity 53, member A
FAM58A family with sequence similarity 58, member A
FASN fatty acid synthase
FASTKD5 FAST kinase domains 5
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FH fumarate hydratase
FLVCR1-AS1 FLVCR1 antisense RNA 1 (head to head)
FOXD4L3 forkhead box D4-like 3
FOXRED1 FAD-dependent oxidoreductase domain containing 1
FTH1 ferritin, heavy polypeptide 1
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
GAK cyclin G associated kinase
GATA4 GATA binding protein 4
GATAD2B GATA zinc finger domain containing 2B
GEMIN8 gem (nuclear organelle) associated protein 8
GHDC GH3 domain containing
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GLIS1 GLIS family zinc finger 1
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GP2 glycoprotein 2 (zymogen granule membrane)
GPM6A glycoprotein M6A
GPR161 G protein-coupled receptor 161
GPR89A G protein-coupled receptor 89A
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSS glutathione synthetase
GZF1 GDNF-inducible zinc finger protein 1
HCRT hypocretin (orexin) neuropeptide precursor
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HIST1H4G histone cluster 1, H4g
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HR hair growth associated
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HTT huntingtin
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFI35 interferon-induced protein 35
IFNB1 interferon, beta 1, fibroblast
INCENP inner centromere protein antigens 135/155kDa
INTS3 integrator complex subunit 3
IRF7 interferon regulatory factor 7
ITGB1BP1 integrin beta 1 binding protein 1
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA1614 KIAA1614
KRTAP13-2 keratin associated protein 13-2
LINC01465 long intergenic non-protein coding RNA 1465
LIX1L Lix1 homolog (chicken) like
LMNA lamin A/C
LOC100134368 uncharacterized LOC100134368
LOC283856 uncharacterized LOC283856
LPIN3 lipin 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC23 leucine rich repeat containing 23
LRRC30 leucine rich repeat containing 30
LRRC46 leucine rich repeat containing 46
MAEA macrophage erythroblast attacher
MAGEB4 melanoma antigen family B4
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAVS mitochondrial antiviral signaling protein
MECP2 methyl CpG binding protein 2
MEIG1 meiosis/spermiogenesis associated 1
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MFSD10 major facilitator superfamily domain containing 10
MFSD7 major facilitator superfamily domain containing 7
MGC16025 uncharacterized LOC85009
MIF4GD MIF4G domain containing
MIPEP mitochondrial intermediate peptidase
MKS1 Meckel syndrome, type 1
MOCS3 molybdenum cofactor synthesis 3
MPC2 mitochondrial pyruvate carrier 2
MPV17L MPV17 mitochondrial membrane protein-like
MRGBP MRG/MORF4L binding protein
MROH8 maestro heat-like repeat family member 8
MRPL24 mitochondrial ribosomal protein L24
MRPL43 mitochondrial ribosomal protein L43
MRPS16 mitochondrial ribosomal protein S16
MRPS26 mitochondrial ribosomal protein S26
MYH7B myosin, heavy chain 7B, cardiac muscle, beta
MYO15A myosin XVA
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NACAD NAC alpha domain containing
NALCN sodium leak channel, non selective
NCOA6 nuclear receptor coactivator 6
NDRG3 NDRG family member 3
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEK8 NIMA-related kinase 8
NELFCD negative elongation factor complex member C/D
NFS1 NFS1 cysteine desulfurase
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NIT1 nitrilase 1
NOP14-AS1 NOP14 antisense RNA 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRG3 neuregulin 3
NRSN2 neurensin 2
NSFL1C NSFL1 (p97) cofactor (p47)
NSG1 neuron specific gene family member 1
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NUTM2A NUT family member 2A
OAT ornithine aminotransferase
OGFR opioid growth factor receptor
OR10W1 olfactory receptor, family 10, subfamily W, member 1
OR14J1 olfactory receptor, family 14, subfamily J, member 1
OR1L3 olfactory receptor, family 1, subfamily L, member 3
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR2K2 olfactory receptor, family 2, subfamily K, member 2
OR2M7 olfactory receptor, family 2, subfamily M, member 7
OR2W3 olfactory receptor, family 2, subfamily W, member 3
OSER1 oxidative stress responsive serine-rich 1
OTC ornithine carbamoyltransferase
PARL presenilin associated, rhomboid-like
PATE1 prostate and testis expressed 1
PCBP4 poly(rC) binding protein 4
PCDHGA11 protocadherin gamma subfamily A, 11
PCIF1 PDX1 C-terminal inhibiting factor 1
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM4 PDZ and LIM domain 4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PORCN porcupine homolog (Drosophila)
POU3F1 POU class 3 homeobox 1
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PPP3R2 protein phosphatase 3, regulatory subunit B, beta
PRB3 proline-rich protein BstNI subfamily 3
PRCC papillary renal cell carcinoma (translocation-associated)
PRH1 proline-rich protein HaeIII subfamily 1
PRH2 proline-rich protein HaeIII subfamily 2
PRKCD protein kinase C, delta
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRR19 proline rich 19
PRR7 proline rich 7 (synaptic)
PSEN2 presenilin 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTPRA protein tyrosine phosphatase, receptor type, A
PYCR2 pyrroline-5-carboxylate reductase family, member 2
PYGB phosphorylase, glycogen; brain
QDPR quinoid dihydropteridine reductase
RAB9A RAB9A, member RAS oncogene family
RAE1 ribonucleic acid export 1
RAI1 retinoic acid induced 1
RALY RALY heterogeneous nuclear ribonucleoprotein
RBBP7 retinoblastoma binding protein 7
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBM38 RNA binding motif protein 38
RBM8A RNA binding motif protein 8A
RELL1 RELT-like 1
RELL2 RELT-like 2
RENBP renin binding protein
RNASE11 ribonuclease, RNase A family, 11 (non-active)
RNF135 ring finger protein 135
RNF187 ring finger protein 187
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RSAD1 radical S-adenosyl methionine domain containing 1
RTFDC1 replication termination factor 2 domain containing 1
RTP2 receptor (chemosensory) transporter protein 2
RUNDC1 RUN domain containing 1
S100A6 S100 calcium binding protein A6
SAP18 Sin3A-associated protein, 18kDa
SCAND1 SCAN domain containing 1
SCCPDH saccharopine dehydrogenase (putative)
SCGB1D1 secretoglobin, family 1D, member 1
SCGN secretagogin, EF-hand calcium binding protein
SCRN2 secernin 2
SDC4 syndecan 4
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SFXN3 sideroflexin 3
SHROOM2 shroom family member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC36A3 solute carrier family 36, member 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SNAPIN SNAP-associated protein
SNHG11 small nucleolar RNA host gene 11
SNORA14B small nucleolar RNA, H/ACA box 14B
SNORA22 small nucleolar RNA, H/ACA box 22
SNORA45B small nucleolar RNA, H/ACA box 45B
SNORA72 small nucleolar RNA, H/ACA box 72
SOX12 SRY (sex determining region Y)-box 12
SOX13 SRY (sex determining region Y)-box 13
SPATA2 spermatogenesis associated 2
SPO11 SPO11 meiotic protein covalently bound to DSB
SPRTN SprT-like N-terminal domain
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSTR4 somatostatin receptor 4
STBD1 starch binding domain 1
STK35 serine/threonine kinase 35
STOM stomatin
STX6 syntaxin 6
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TADA2B transcriptional adaptor 2B
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TAZ tafazzin
TBC1D14 TBC1 domain family, member 14
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TEX35 testis expressed 35
TFDP3 transcription factor Dp family, member 3
THAP4 THAP domain containing 4
THRAP3 thyroid hormone receptor associated protein 3
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase
TMEM143 transmembrane protein 143
TMEM177 transmembrane protein 177
TMEM180 transmembrane protein 180
TMEM185B transmembrane protein 185B
TMEM187 transmembrane protein 187
TMEM189 transmembrane protein 189
TMEM199 transmembrane protein 199
TMEM25 transmembrane protein 25
TMEM9 transmembrane protein 9
TMX4 thioredoxin-related transmembrane protein 4
TNNI3K TNNI3 interacting kinase
TP53BP2 tumor protein p53 binding protein 2
TP53I13 tumor protein p53 inducible protein 13
TP53INP2 tumor protein p53 inducible nuclear protein 2
TP53RK TP53 regulating kinase
TPM3 tropomyosin 3
TRIM34 tripartite motif containing 34
TRIM47 tripartite motif containing 47
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC13 tetratricopeptide repeat domain 13
TTC36 tetratricopeptide repeat domain 36
TTC8 tetratricopeptide repeat domain 8
TUBA8 tubulin, alpha 8
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TYSND1 trypsin domain containing 1
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBOX5 U-box domain containing 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCN2 urocortin 2
UFC1 ubiquitin-fold modifier conjugating enzyme 1
UNC13D unc-13 homolog D (C. elegans)
UNK unkempt family zinc finger
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
UROS uroporphyrinogen III synthase
USP18 ubiquitin specific peptidase 18
USP27X ubiquitin specific peptidase 27, X-linked
VDAC1 voltage-dependent anion channel 1
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
WDR1 WD repeat domain 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZBTB42 zinc finger and BTB domain containing 42
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF287 zinc finger protein 287
ZNF362 zinc finger protein 362
ZNF516 zinc finger protein 516
ZSWIM1 zinc finger, SWIM-type containing 1

low expression

Symbol Name
RABL3 RAB, member of RAS oncogene family-like 3