Sinusitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. (Human Disease Ontology, DOID_0050127)
Similar Terms
Downloads & Tools

Genes

51 genes associated with the Sinusitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AOAH acyloxyacyl hydrolase (neutrophil)
CD8A CD8a molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
EBI3 Epstein-Barr virus induced 3
FOXP3 forkhead box P3
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL22RA1 interleukin 22 receptor, alpha 1
IL4 interleukin 4
IL6 interleukin 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
LTA lymphotoxin alpha
LTC4S leukotriene C4 synthase
LTF lactotransferrin
MET MET proto-oncogene, receptor tyrosine kinase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
NOS1 nitric oxide synthase 1 (neuronal)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUNX2 runt-related transcription factor 2
RYBP RING1 and YY1 binding protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAS2R13 taste receptor, type 2, member 13
TAS2R20 taste receptor, type 2, member 20
TAS2R3 taste receptor, type 2, member 3
TAS2R38 taste receptor, type 2, member 38
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TP73 tumor protein p73
TSLP thymic stromal lymphopoietin