Signaling events mediated by focal adhesion kinase Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/8fb80085-6195-11e5-8ac5-06603eb7f303
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Genes

58 proteins participating in the Signaling events mediated by focal adhesion kinase pathway from the PID Pathways dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACTN1 actinin, alpha 1
ARHGAP26 Rho GTPase activating protein 26
ARHGAP35 Rho GTPase activating protein 35
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAPN2 calpain 2, (m/II) large subunit
CCND1 cyclin D1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DOCK1 dedicator of cytokinesis 1
ELMO1 engulfment and cell motility 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JUN jun proto-oncogene
KLF8 Kruppel-like factor 8
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPK9 mitogen-activated protein kinase 9
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RHOA ras homolog family member A
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRAS related RAS viral (r-ras) oncogene homolog
SH3GL1 SH3-domain GRB2-like 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TLN1 talin 1
VCL vinculin
WASL Wiskott-Aldrich syndrome-like
YES1 YES proto-oncogene 1, Src family tyrosine kinase