Signaling events mediated by TCPTP Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/cd5ca44d-6195-11e5-8ac5-06603eb7f303
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Genes

40 proteins participating in the Signaling events mediated by TCPTP pathway from the PID Pathways dataset.

Symbol Name
ATR ATR serine/threonine kinase
CREBBP CREB binding protein
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
INS insulin
INSR insulin receptor
ITGA1 integrin, alpha 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KDR kinase insert domain receptor
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNB1 karyopherin (importin) beta 1
LMAN1 lectin, mannose-binding, 1
MET MET proto-oncogene, receptor tyrosine kinase
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIAS1 protein inhibitor of activated STAT, 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB4A RAB4A, member RAS oncogene family
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
VEGFA vascular endothelial growth factor A