Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/ac39d2b9-6195-11e5-8ac5-06603eb7f303
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Genes

75 proteins participating in the Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) pathway from the PID Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
APC adenomatous polyposis coli
ARF6 ADP-ribosylation factor 6
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DEPTOR DEP domain containing MTOR-interacting protein
EGR1 early growth response 1
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPS15 epidermal growth factor receptor pathway substrate 15
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GRB2 growth factor receptor-bound protein 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HRAS Harvey rat sarcoma viral oncogene homolog
INPPL1 inositol polyphosphate phosphatase-like 1
JUN jun proto-oncogene
KPNB1 karyopherin (importin) beta 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC20 mucin 20, cell surface associated
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NUMB numb homolog (Drosophila)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARD6A par-6 family cell polarity regulator alpha
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
RAB5A RAB5A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP10 RAN binding protein 10
RANBP9 RAN binding protein 9
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RHOA ras homolog family member A
RIN2 Ras and Rab interactor 2
RPTOR regulatory associated protein of MTOR, complex 1
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SNAI1 snail family zinc finger 1
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
WASL Wiskott-Aldrich syndrome-like