Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
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Genes

72 proteins participating in the Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway from the Reactome Pathways dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
CCNC cyclin C
CDK8 cyclin-dependent kinase 8
CNTN1 contactin 1
CREBBP CREB binding protein
CUL1 cullin 1
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNER delta/notch-like EGF repeat containing
DTX1 deltex 1, E3 ubiquitin ligase
DTX2 deltex 2, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
EP300 E1A binding protein p300
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
HDAC1 histone deacetylase 1
HDAC10 histone deacetylase 10
HDAC11 histone deacetylase 11
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HDAC7 histone deacetylase 7
HDAC8 histone deacetylase 8
HDAC9 histone deacetylase 9
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ITCH itchy E3 ubiquitin protein ligase
JAG1 jagged 1
JAG2 jagged 2
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAMLD1 mastermind-like domain containing 1
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIB2 mindbomb E3 ubiquitin protein ligase 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEURL1B neuralized E3 ubiquitin protein ligase 1B
NOTCH1 notch 1
NUMB numb homolog (Drosophila)
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SKP1 S-phase kinase-associated protein 1
SNW1 SNW domain containing 1
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C