Sickle Cell Anemia_Endothelial cell_GSE9877 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9877
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Genes

600 genes differentially expressed during Sickle Cell Anemia_Endothelial cell_GSE9877 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
GRM8 glutamate receptor, metabotropic 8 2.90249
ZCCHC4 zinc finger, CCHC domain containing 4 2.80163
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 2.74163
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.6325
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.61038
FCAR Fc fragment of IgA receptor 2.59084
SNX1 sorting nexin 1 2.57572
TADA2A transcriptional adaptor 2A 2.56593
ZNF614 zinc finger protein 614 2.54033
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.5194
KIF24 kinesin family member 24 2.49858
NRF1 nuclear respiratory factor 1 2.48952
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.47393
EPHA3 EPH receptor A3 2.46783
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.44095
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.42927
PRDM9 PR domain containing 9 2.41524
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 2.40801
PLCH1 phospholipase C, eta 1 2.3813
SNTG1 syntrophin, gamma 1 2.34875
HPS4 Hermansky-Pudlak syndrome 4 2.33364
LRRC19 leucine rich repeat containing 19 2.33268
NF1 neurofibromin 1 2.33196
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.32694
C9ORF156 chromosome 9 open reading frame 156 2.30919
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.30861
CLTC clathrin, heavy chain (Hc) 2.30829
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 2.30735
TRGV5 T cell receptor gamma variable 5 2.28605
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.28605
PWWP2A PWWP domain containing 2A 2.28079
ADRA1A adrenoceptor alpha 1A 2.26586
RECQL5 RecQ protein-like 5 2.26549
GPR107 G protein-coupled receptor 107 2.25961
TROVE2 TROVE domain family, member 2 2.23084
PVT1 Pvt1 oncogene (non-protein coding) 2.19877
HIST2H2AA3 histone cluster 2, H2aa3 2.18631
SHISA6 shisa family member 6 2.17013
KIAA1045 KIAA1045 2.16315
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 2.15677
INHBE inhibin, beta E 2.15033
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.13427
FGFR2 fibroblast growth factor receptor 2 2.12762
MYB v-myb avian myeloblastosis viral oncogene homolog 2.12392
EFCAB11 EF-hand calcium binding domain 11 2.12345
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 2.10908
GPR85 G protein-coupled receptor 85 2.10659
MED14 mediator complex subunit 14 2.10586
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.10488
XYLB xylulokinase homolog (H. influenzae) 2.0914
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.0845
EEF1G eukaryotic translation elongation factor 1 gamma 2.0839
TBCA tubulin folding cofactor A 2.08173
IGKV4-1 immunoglobulin kappa variable 4-1 2.07894
THRA thyroid hormone receptor, alpha 2.07862
GH1 growth hormone 1 2.07677
ZNF79 zinc finger protein 79 2.06984
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.06685
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 2.06658
ENOX2 ecto-NOX disulfide-thiol exchanger 2 2.06144
SEPT4 septin 4 2.06048
AAMP angio-associated, migratory cell protein 2.05036
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.0472
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 2.02398
RGS12 regulator of G-protein signaling 12 2.01729
CDH8 cadherin 8, type 2 2.01604
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 2.01496
NOX1 NADPH oxidase 1 2.00747
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.00587
CLCA2 chloride channel accessory 2 2.00508
GTPBP1 GTP binding protein 1 2.00376
RBM12B RNA binding motif protein 12B 2.00242
C18ORF25 chromosome 18 open reading frame 25 1.99983
CRHR2 corticotropin releasing hormone receptor 2 1.99822
TOX4 TOX high mobility group box family member 4 1.99801
GLP1R glucagon-like peptide 1 receptor 1.99604
OPN5 opsin 5 1.9919
INADL InaD-like (Drosophila) 1.98786
BCL9 B-cell CLL/lymphoma 9 1.98173
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 1.9791
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 1.97577
FGF20 fibroblast growth factor 20 1.97495
MAP2K5 mitogen-activated protein kinase kinase 5 1.97137
FBXO42 F-box protein 42 1.96279
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.95935
INVS inversin 1.95481
TOX3 TOX high mobility group box family member 3 1.95206
MAG myelin associated glycoprotein 1.94864
FBXO31 F-box protein 31 1.9484
ZNF212 zinc finger protein 212 1.94402
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.9438
DMC1 DNA meiotic recombinase 1 1.94299
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.941
LMAN2 lectin, mannose-binding 2 1.93727
PAQR5 progestin and adipoQ receptor family member V 1.93377
IVD isovaleryl-CoA dehydrogenase 1.93295
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.92575
RGS1 regulator of G-protein signaling 1 1.92493
ELL elongation factor RNA polymerase II 1.92424
FAM149A family with sequence similarity 149, member A 1.9224
OVOL2 ovo-like zinc finger 2 1.92075
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.90791
ZNF174 zinc finger protein 174 1.90357
SH2D3A SH2 domain containing 3A 1.90276
TRERF1 transcriptional regulating factor 1 1.89615
TRIP11 thyroid hormone receptor interactor 11 1.88867
MCM3AP minichromosome maintenance complex component 3 associated protein 1.88669
RAB5A RAB5A, member RAS oncogene family 1.88614
KLHL23 kelch-like family member 23 1.8818
GRIK1 glutamate receptor, ionotropic, kainate 1 1.88153
CCL17 chemokine (C-C motif) ligand 17 1.88139
PRDM2 PR domain containing 2, with ZNF domain 1.8794
HEATR6 HEAT repeat containing 6 1.87572
MUC7 mucin 7, secreted 1.86869
NUP188 nucleoporin 188kDa 1.86856
VEZT vezatin, adherens junctions transmembrane protein 1.86813
KRI1 KRI1 homolog (S. cerevisiae) 1.86778
NPAT nuclear protein, ataxia-telangiectasia locus 1.86715
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.86469
SBSPON somatomedin B and thrombospondin, type 1 domain containing 1.8641
ANKRD40 ankyrin repeat domain 40 1.85682
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.85591
DEC1 deleted in esophageal cancer 1 1.85563
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.8536
DOPEY2 dopey family member 2 1.85094
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 1.84987
ADAM3B ADAM metallopeptidase domain 3B (pseudogene) 1.84925
BAIAP2L2 BAI1-associated protein 2-like 2 1.84471
ANKMY1 ankyrin repeat and MYND domain containing 1 1.83817
BAZ2A bromodomain adjacent to zinc finger domain, 2A 1.83799
NAV1 neuron navigator 1 1.83523
ALDOB aldolase B, fructose-bisphosphate 1.83507
KIAA1614 KIAA1614 1.83035
SLC39A9 solute carrier family 39, member 9 1.82934
ATP9B ATPase, class II, type 9B 1.82903
TRIM15 tripartite motif containing 15 1.81945
ANKRD17 ankyrin repeat domain 17 1.81921
TTC22 tetratricopeptide repeat domain 22 1.81729
JRK Jrk homolog (mouse) 1.81517
MOCS3 molybdenum cofactor synthesis 3 1.8149
NCALD neurocalcin delta 1.81441
ZNF710 zinc finger protein 710 1.81285
NUP210 nucleoporin 210kDa 1.81221
SMG6 SMG6 nonsense mediated mRNA decay factor 1.81126
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.81056
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.80912
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2 1.8083
NCOR1 nuclear receptor corepressor 1 1.8079
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.80523
DCAKD dephospho-CoA kinase domain containing 1.80355
GRM5 glutamate receptor, metabotropic 5 1.80023
ZBTB17 zinc finger and BTB domain containing 17 1.79756
DGCR14 DiGeorge syndrome critical region gene 14 1.79617
NGDN neuroguidin, EIF4E binding protein 1.79341
ZNF639 zinc finger protein 639 1.79086
RAD17 RAD17 homolog (S. pombe) 1.78606
MIA melanoma inhibitory activity 1.78477
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 1.78281
CREBZF CREB/ATF bZIP transcription factor 1.77753
DLG3 discs, large homolog 3 (Drosophila) 1.77649
MOG myelin oligodendrocyte glycoprotein 1.77178
ASTN1 astrotactin 1 1.76859
MDM4 MDM4, p53 regulator 1.76816
ANKRD36BP2 ankyrin repeat domain 36B pseudogene 2 1.76696
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.76544
GNAS GNAS complex locus 1.76408
C7ORF33 chromosome 7 open reading frame 33 1.76395
BRD9 bromodomain containing 9 1.7624
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.76233
SKI SKI proto-oncogene 1.76189
SYMPK symplekin 1.76087
RPL35A ribosomal protein L35a 1.76079
C7ORF26 chromosome 7 open reading frame 26 1.75781
ZNF492 zinc finger protein 492 1.74521
SIK3 SIK family kinase 3 1.74353
SETD2 SET domain containing 2 1.74287
THPO thrombopoietin 1.74062
BCAP29 B-cell receptor-associated protein 29 1.74052
DFNB31 deafness, autosomal recessive 31 1.74006
NRG2 neuregulin 2 1.73908
HCG4B HLA complex group 4B (non-protein coding) 1.73754
DCAF15 DDB1 and CUL4 associated factor 15 1.73722
ZNF407 zinc finger protein 407 1.73203
FAM114A2 family with sequence similarity 114, member A2 1.73197
ZNF440 zinc finger protein 440 1.72944
THOC5 THO complex 5 1.72936
TF transferrin 1.72826
RAB11FIP3 RAB11 family interacting protein 3 (class II) 1.72752
SAMD14 sterile alpha motif domain containing 14 1.72608
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 1.7242
MYT1 myelin transcription factor 1 1.72404
RPLP1 ribosomal protein, large, P1 1.72265
APOA2 apolipoprotein A-II 1.72155
ST20 suppressor of tumorigenicity 20 1.7197
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.71805
LPAR4 lysophosphatidic acid receptor 4 1.71722
YME1L1 YME1-like 1 ATPase 1.71669
ASTN2 astrotactin 2 1.71653
IFT122 intraflagellar transport 122 1.71574
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) 1.71547
TBL1Y transducin (beta)-like 1, Y-linked 1.71533
CSNK2B casein kinase 2, beta polypeptide 1.7145
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.71351
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.71171
PDCD1 programmed cell death 1 1.70902
MSMB microseminoprotein, beta- 1.70892
SGSM3 small G protein signaling modulator 3 1.70782
IST1 increased sodium tolerance 1 homolog (yeast) 1.7068
ZNF234 zinc finger protein 234 1.70605
GUCA1A guanylate cyclase activator 1A (retina) 1.70319
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 1.70257
ATXN7L1 ataxin 7-like 1 1.70045
GPATCH8 G patch domain containing 8 1.69573
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.6944
ADAMTSL2 ADAMTS-like 2 1.69402
AQP4 aquaporin 4 1.69211
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.69074
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.69067
ARHGAP1 Rho GTPase activating protein 1 1.69019
UBE3A ubiquitin protein ligase E3A 1.69013
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.68974
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.68917
WIPF2 WAS/WASL interacting protein family, member 2 1.68845
CDK10 cyclin-dependent kinase 10 1.68797
CADM4 cell adhesion molecule 4 1.68791
SHOX2 short stature homeobox 2 1.68764
GREB1 growth regulation by estrogen in breast cancer 1 1.68744
STXBP3 syntaxin binding protein 3 1.68639
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 1.68535
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.68411
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.68376
GOSR1 golgi SNAP receptor complex member 1 1.68316
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 1.68
SENP5 SUMO1/sentrin specific peptidase 5 1.67952
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.67681
TGM4 transglutaminase 4 1.67497
TRAF3IP3 TRAF3 interacting protein 3 1.67367
RREB1 ras responsive element binding protein 1 1.67075
KLHL11 kelch-like family member 11 1.66662
DGCR6 DiGeorge syndrome critical region gene 6 1.66482
ZNF134 zinc finger protein 134 1.66434
DNASE2B deoxyribonuclease II beta 1.66351
GRIK2 glutamate receptor, ionotropic, kainate 2 1.66327
IRF4 interferon regulatory factor 4 1.66324
KDM2A lysine (K)-specific demethylase 2A 1.66277
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.66013
SNX3 sorting nexin 3 1.65978
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.65795
CHP1 calcineurin-like EF-hand protein 1 1.65751
NCAM1 neural cell adhesion molecule 1 1.65634
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.65126
C10ORF95 chromosome 10 open reading frame 95 1.6499
ACOXL acyl-CoA oxidase-like 1.64979
FGB fibrinogen beta chain 1.64898
THNSL1 threonine synthase-like 1 (S. cerevisiae) 1.64897
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.6469
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.64573
CNOT4 CCR4-NOT transcription complex, subunit 4 1.64428
SETD4 SET domain containing 4 1.64245
PCYT1B phosphate cytidylyltransferase 1, choline, beta 1.6379
CSDE1 cold shock domain containing E1, RNA-binding 1.63751
MFAP3 microfibrillar-associated protein 3 1.63398
BAIAP3 BAI1-associated protein 3 1.62971
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 1.62462
SOX5 SRY (sex determining region Y)-box 5 1.62098
FLJ11292 1.61867
ZNF764 zinc finger protein 764 1.61857
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.61765
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 1.61554
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.61414
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.61236
FABP3 fatty acid binding protein 3, muscle and heart 1.61225
SATB2 SATB homeobox 2 1.61198
CD28 CD28 molecule 1.60898
ATXN3 ataxin 3 1.60866
PCDHGB6 protocadherin gamma subfamily B, 6 1.60668
SIAH1 siah E3 ubiquitin protein ligase 1 1.60656
TRAF3IP2 TRAF3 interacting protein 2 1.6035
FLJ11710 uncharacterized protein FLJ11710 1.60324
RUNDC3A RUN domain containing 3A 1.60304
CD72 CD72 molecule 1.6015
HRASLS2 HRAS-like suppressor 2 1.6004
RBBP9 retinoblastoma binding protein 9 1.59751
AMELX amelogenin, X-linked 1.59691
ZNF35 zinc finger protein 35 1.59583
AGBL3 ATP/GTP binding protein-like 3 1.59454
FAM134B family with sequence similarity 134, member B 1.59432
GATA4 GATA binding protein 4 1.59425
BRAP BRCA1 associated protein 1.59378
MECP2 methyl CpG binding protein 2 1.59377
PTK6 protein tyrosine kinase 6 1.59259
TMCC2 transmembrane and coiled-coil domain family 2 1.59009
POLG polymerase (DNA directed), gamma 1.5898
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.58791
ERP44 endoplasmic reticulum protein 44 1.58754
KRT81 keratin 81, type II 1.58731
FBXO22 F-box protein 22 1.58728
PCNX pecanex homolog (Drosophila) 1.5871
CCDC14 coiled-coil domain containing 14 1.5853
AGK acylglycerol kinase 1.58393

decreased expression

Symbol Name Standardized Value
FAM208B family with sequence similarity 208, member B -1.19097
RPL23AP22 ribosomal protein L23a pseudogene 22 -0.723604
KHK ketohexokinase (fructokinase) -0.715082
C5ORF45 chromosome 5 open reading frame 45 -0.67091
LYZL6 lysozyme-like 6 -0.669327
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -0.665963
TMEM143 transmembrane protein 143 -0.664359
LDB1 LIM domain binding 1 -0.633776
POU3F3 POU class 3 homeobox 3 -0.602435
SLIT1 slit homolog 1 (Drosophila) -0.597959
FAM66D family with sequence similarity 66, member D -0.582587
AQP5 aquaporin 5 -0.582106
STAP1 signal transducing adaptor family member 1 -0.578673
COL19A1 collagen, type XIX, alpha 1 -0.578582
CXXC4 CXXC finger protein 4 -0.570908
FCHO1 FCH domain only 1 -0.568091
DEFB4A defensin, beta 4A -0.553641
CTRB1 chymotrypsinogen B1 -0.545226
ZIC4 Zic family member 4 -0.530058
RPS11P1 ribosomal protein S11 pseudogene 1 -0.521751
FGF4 fibroblast growth factor 4 -0.514346
CTSW cathepsin W -0.507976
OR10J1 olfactory receptor, family 10, subfamily J, member 1 -0.496327
CFAP70 cilia and flagella associated protein 70 -0.49204
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -0.465125
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.462434
NPC1L1 NPC1-like 1 -0.462195
INA internexin neuronal intermediate filament protein, alpha -0.459301
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -0.453609
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 -0.447963
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 -0.44667
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -0.44567
MGC2889 uncharacterized protein MGC2889 -0.43279
LARP1 La ribonucleoprotein domain family, member 1 -0.431446
FGF1 fibroblast growth factor 1 (acidic) -0.431194
CORO2A coronin, actin binding protein, 2A -0.430082
RDH8 retinol dehydrogenase 8 (all-trans) -0.427711
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 -0.421991
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -0.42082
INE1 inactivation escape 1 (non-protein coding) -0.413537
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -0.411478
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -0.41009
DRP2 dystrophin related protein 2 -0.409388
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -0.406756
MYO9A myosin IXA -0.406068
CDH12 cadherin 12, type 2 (N-cadherin 2) -0.404451
FGF7 fibroblast growth factor 7 -0.395122
LBX1 ladybird homeobox 1 -0.391523
CLK2 CDC-like kinase 2 -0.391522
IL18BP interleukin 18 binding protein -0.388234
FRMPD1 FERM and PDZ domain containing 1 -0.386946
SCGN secretagogin, EF-hand calcium binding protein -0.380131
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.37711
CHRND cholinergic receptor, nicotinic, delta (muscle) -0.371838
HOXC13 homeobox C13 -0.366791
TAS2R1 taste receptor, type 2, member 1 -0.365417
GPR45 G protein-coupled receptor 45 -0.36511
TOP1 topoisomerase (DNA) I -0.363475
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -0.363325
WNT1 wingless-type MMTV integration site family, member 1 -0.359966
FRMD1 FERM domain containing 1 -0.359724
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.35891
PENK proenkephalin -0.355354
ALG11 ALG11, alpha-1,2-mannosyltransferase -0.353843
HOXB1 homeobox B1 -0.353542
CCNT1 cyclin T1 -0.351912
CHD4 chromodomain helicase DNA binding protein 4 -0.351909
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.351871
EPN3 epsin 3 -0.351659
DLG4 discs, large homolog 4 (Drosophila) -0.35145
ANKRD11 ankyrin repeat domain 11 -0.350505
CRYAA crystallin, alpha A -0.349936
HIST1H1D histone cluster 1, H1d -0.347108
ADAM7 ADAM metallopeptidase domain 7 -0.344507
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -0.339571
CD3G CD3g molecule, gamma (CD3-TCR complex) -0.337357
TPH2 tryptophan hydroxylase 2 -0.334819
DRD4 dopamine receptor D4 -0.334703
TMEM223 transmembrane protein 223 -0.334383
AFG3L2 AFG3-like AAA ATPase 2 -0.330834
PADI1 peptidyl arginine deiminase, type I -0.327617
NPHP1 nephronophthisis 1 (juvenile) -0.326648
ARL15 ADP-ribosylation factor-like 15 -0.325696
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.325625
RNF39 ring finger protein 39 -0.322907
GTF2A1 general transcription factor IIA, 1, 19/37kDa -0.322386
ACSM1 acyl-CoA synthetase medium-chain family member 1 -0.321904
MLN motilin -0.320688
PARP6 poly (ADP-ribose) polymerase family, member 6 -0.318587
MOSPD2 motile sperm domain containing 2 -0.318565
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.318508
ERCC1 excision repair cross-complementation group 1 -0.315192
ALPP alkaline phosphatase, placental -0.315092
OAF OAF homolog (Drosophila) -0.311962
GNMT glycine N-methyltransferase -0.30844
CLDN6 claudin 6 -0.307403
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding) -0.30685
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) -0.306644
SPERT spermatid associated -0.305997
GK2 glycerol kinase 2 -0.30275
AMOT angiomotin -0.302619
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -0.302342
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -0.301036
VNN2 vanin 2 -0.300591
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -0.296612
IGLV6-57 immunoglobulin lambda variable 6-57 -0.294257
ARHGAP32 Rho GTPase activating protein 32 -0.294004
SPACA1 sperm acrosome associated 1 -0.293154
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.292749
ZNHIT2 zinc finger, HIT-type containing 2 -0.292288
AQP8 aquaporin 8 -0.28987
HBZ hemoglobin, zeta -0.287491
CCL22 chemokine (C-C motif) ligand 22 -0.287191
HIST1H4D histone cluster 1, H4d -0.286644
SDK2 sidekick cell adhesion molecule 2 -0.286435
NCAN neurocan -0.285981
CD8A CD8a molecule -0.283231
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.282075
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) -0.281633
PIGR polymeric immunoglobulin receptor -0.278265
TM4SF20 transmembrane 4 L six family member 20 -0.278197
PAPD5 PAP associated domain containing 5 -0.274411
HOXB2 homeobox B2 -0.274136
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -0.2736
IRS4 insulin receptor substrate 4 -0.272342
GRIP2 glutamate receptor interacting protein 2 -0.272109
RIPK4 receptor-interacting serine-threonine kinase 4 -0.271662
AKAP3 A kinase (PRKA) anchor protein 3 -0.270677
GPR3 G protein-coupled receptor 3 -0.270348
FXYD1 FXYD domain containing ion transport regulator 1 -0.270289
USP29 ubiquitin specific peptidase 29 -0.269383
TRIM58 tripartite motif containing 58 -0.2665
GPR173 G protein-coupled receptor 173 -0.265731
PRDM16 PR domain containing 16 -0.262823
RAB26 RAB26, member RAS oncogene family -0.262536
GPR75 G protein-coupled receptor 75 -0.261783
TTC26 tetratricopeptide repeat domain 26 -0.261766
CCL21 chemokine (C-C motif) ligand 21 -0.260552
BTBD9 BTB (POZ) domain containing 9 -0.260017
RAB36 RAB36, member RAS oncogene family -0.259761
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -0.258998
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.258345
CLCA1 chloride channel accessory 1 -0.255433
CD177 CD177 molecule -0.255359
TRHDE thyrotropin-releasing hormone degrading enzyme -0.255354
HAVCR1 hepatitis A virus cellular receptor 1 -0.255096
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 -0.253644
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding) -0.253486
APOA1 apolipoprotein A-I -0.252939
IFNA10 interferon, alpha 10 -0.25131
CBX8 chromobox homolog 8 -0.251282
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 -0.247767
NCF2 neutrophil cytosolic factor 2 -0.247608
KLHL25 kelch-like family member 25 -0.245846
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) -0.242878
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 -0.242548
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -0.241241
ODAM odontogenic, ameloblast asssociated -0.23899
MYCNOS MYCN opposite strand -0.238016
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -0.236726
EPHB3 EPH receptor B3 -0.235965
GAGE12I G antigen 12I -0.234651
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -0.234521
GPRC5D G protein-coupled receptor, class C, group 5, member D -0.23424
GJB5 gap junction protein, beta 5, 31.1kDa -0.232153
LY6D lymphocyte antigen 6 complex, locus D -0.2311
ADIPOQ adiponectin, C1Q and collagen domain containing -0.230197
LSP1 lymphocyte-specific protein 1 -0.229767
MYBPC3 myosin binding protein C, cardiac -0.228067
SPIN1 spindlin 1 -0.2278
TCP10L t-complex 10-like -0.226113
MYO15A myosin XVA -0.225263
FGF16 fibroblast growth factor 16 -0.224399
MOXD1 monooxygenase, DBH-like 1 -0.223537
MAGEA6 melanoma antigen family A6 -0.221967
H2AFB2 H2A histone family, member B2 -0.221618
PPP1R10 protein phosphatase 1, regulatory subunit 10 -0.221612
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 -0.220892
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.220116
PLA2G2D phospholipase A2, group IID -0.219028
DLX6 distal-less homeobox 6 -0.218409
AGRP agouti related neuropeptide -0.218113
TAS2R7 taste receptor, type 2, member 7 -0.218046
CXORF21 chromosome X open reading frame 21 -0.218005
DSG3 desmoglein 3 -0.216324
C22ORF24 chromosome 22 open reading frame 24 -0.214537
DDO D-aspartate oxidase -0.21422
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.213213
LGALS4 lectin, galactoside-binding, soluble, 4 -0.211059
FAM65B family with sequence similarity 65, member B -0.2103
INPPL1 inositol polyphosphate phosphatase-like 1 -0.210239
CORO2B coronin, actin binding protein, 2B -0.209729
RBP3 retinol binding protein 3, interstitial -0.208956
CA5A carbonic anhydrase VA, mitochondrial -0.208481
ZNF654 zinc finger protein 654 -0.207538
C2ORF83 chromosome 2 open reading frame 83 -0.20662
TRBC1 T cell receptor beta constant 1 -0.206244
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 -0.206136
MUC16 mucin 16, cell surface associated -0.205406
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.204689
HOXC11 homeobox C11 -0.204451
LIME1 Lck interacting transmembrane adaptor 1 -0.203439
TMPRSS5 transmembrane protease, serine 5 -0.200894
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) -0.200557
SYTL2 synaptotagmin-like 2 -0.200532
ZNF141 zinc finger protein 141 -0.197727
FOXN3-AS2 FOXN3 antisense RNA 2 -0.195264
CHRM4 cholinergic receptor, muscarinic 4 -0.195247
ZNF132 zinc finger protein 132 -0.195216
RFX7 regulatory factor X, 7 -0.194473
SCRIB scribbled planar cell polarity protein -0.194189
IL17B interleukin 17B -0.193943
GNRH2 gonadotropin-releasing hormone 2 -0.192505
OBP2A odorant binding protein 2A -0.190796
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -0.19061
CDSN corneodesmosin -0.190117
FOXJ1 forkhead box J1 -0.18932
RPAP2 RNA polymerase II associated protein 2 -0.189076
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.188238
RORC RAR-related orphan receptor C -0.187783
ACTL7A actin-like 7A -0.187407
CDHR5 cadherin-related family member 5 -0.186524
TM4SF4 transmembrane 4 L six family member 4 -0.186413
CCR4 chemokine (C-C motif) receptor 4 -0.185848
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta -0.185119
KCNK2 potassium channel, two pore domain subfamily K, member 2 -0.184496
GPC2 glypican 2 -0.184047
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 -0.182903
MXRA8 matrix-remodelling associated 8 -0.18282
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.182788
PSG4 pregnancy specific beta-1-glycoprotein 4 -0.181808
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -0.181152
SYCP1 synaptonemal complex protein 1 -0.181005
S100A13 S100 calcium binding protein A13 -0.180035
LENEP lens epithelial protein -0.177294
PSG1 pregnancy specific beta-1-glycoprotein 1 -0.177191
CNR2 cannabinoid receptor 2 (macrophage) -0.177018
VPREB1 pre-B lymphocyte 1 -0.176445
REEP2 receptor accessory protein 2 -0.176112
HIST2H2BE histone cluster 2, H2be -0.175913
DPP4 dipeptidyl-peptidase 4 -0.174824
HSPA1B heat shock 70kDa protein 1B -0.17431
HOXD3 homeobox D3 -0.173388
TULP2 tubby like protein 2 -0.173313
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -0.173249
LOR loricrin -0.172762
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -0.171343
RNF122 ring finger protein 122 -0.170234
WNT2 wingless-type MMTV integration site family member 2 -0.16997
RAP2A RAP2A, member of RAS oncogene family -0.169401
NMRK2 nicotinamide riboside kinase 2 -0.168393
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -0.167713
CAV3 caveolin 3 -0.166398
LOC441204 uncharacterized LOC441204 -0.165296
GPR12 G protein-coupled receptor 12 -0.164998
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.164956
CTF1 cardiotrophin 1 -0.163979
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 -0.163952
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -0.162531
KIF5A kinesin family member 5A -0.162206
GPR182 G protein-coupled receptor 182 -0.161985
IGF2 insulin-like growth factor 2 -0.16153
PHC2 polyhomeotic homolog 2 (Drosophila) -0.161215
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.160514
TWSG1 twisted gastrulation BMP signaling modulator 1 -0.159991
MYT1L myelin transcription factor 1-like -0.159915
IPCEF1 interaction protein for cytohesin exchange factors 1 -0.159395
CER1 cerberus 1, DAN family BMP antagonist -0.159292
LECT2 leukocyte cell-derived chemotaxin 2 -0.158237
ASTE1 asteroid homolog 1 (Drosophila) -0.158235
CACFD1 calcium channel flower domain containing 1 -0.157088
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 -0.156918
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -0.156857
LTA lymphotoxin alpha -0.15657
ADGRB2 adhesion G protein-coupled receptor B2 -0.156342
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -0.155765
PSG6 pregnancy specific beta-1-glycoprotein 6 -0.155606
NEFM neurofilament, medium polypeptide -0.155604
NOTCH3 notch 3 -0.155529
OR7E14P olfactory receptor, family 7, subfamily E, member 14 pseudogene -0.155174
NTF3 neurotrophin 3 -0.154972
CYB5R2 cytochrome b5 reductase 2 -0.154163
LEFTY2 left-right determination factor 2 -0.154009
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -0.153862
CCDC130 coiled-coil domain containing 130 -0.153779
MXRA5 matrix-remodelling associated 5 -0.153276
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -0.153017
RGS16 regulator of G-protein signaling 16 -0.152431
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -0.151925
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -0.150882
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -0.150595
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -0.150018
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) -0.149778
ARSF arylsulfatase F -0.148649
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.148475
ADRA2C adrenoceptor alpha 2C -0.147376
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.147062
MYL7 myosin, light chain 7, regulatory -0.146283
CD19 CD19 molecule -0.146253
HIST1H4C histone cluster 1, H4c -0.145719