Shock, Septic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012772
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Genes

63 genes/proteins associated with the disease Shock, Septic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AQP1 aquaporin 1 (Colton blood group) 2.88009
TNF tumor necrosis factor 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
GC group-specific component (vitamin D binding protein) 2.88009
C5AR1 complement component 5a receptor 1 2.88009
IL1B interleukin 1, beta 2.25497
IL6 interleukin 6 2.23208
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.08104
CCL2 chemokine (C-C motif) ligand 2 2.00233
MAPK1 mitogen-activated protein kinase 1 1.88885
IFNG interferon, gamma 1.85887
MAPK3 mitogen-activated protein kinase 3 1.84126
IL10 interleukin 10 1.78473
FOS FBJ murine osteosarcoma viral oncogene homolog 1.70077
VEGFA vascular endothelial growth factor A 1.6947
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.68295
CCL5 chemokine (C-C motif) ligand 5 1.65533
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.61782
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.5721
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.57138
CXCL8 chemokine (C-X-C motif) ligand 8 1.53506
TH tyrosine hydroxylase 1.52816
ICAM1 intercellular adhesion molecule 1 1.4479
CCL3 chemokine (C-C motif) ligand 3 1.4026
HMOX1 heme oxygenase 1 1.39226
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.38213
IL1A interleukin 1, alpha 1.37075
JUN jun proto-oncogene 1.36104
CRH corticotropin releasing hormone 1.34897
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.31596
MAPK8 mitogen-activated protein kinase 8 1.31
NOS1 nitric oxide synthase 1 (neuronal) 1.27132
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.25682
POMC proopiomelanocortin 1.24905
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.2456
BCL2 B-cell CLL/lymphoma 2 1.23011
CXCL2 chemokine (C-X-C motif) ligand 2 1.22979
MMP9 matrix metallopeptidase 9 1.22306
ALB albumin 1.21984
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.21599
CAT catalase 1.21011
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.20946
NPY neuropeptide Y 1.20751
TAC1 tachykinin, precursor 1 1.19246
F3 coagulation factor III (thromboplastin, tissue factor) 1.19146
CTSD cathepsin D 1.16633
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.16203
HRH1 histamine receptor H1 1.15967
DDIT3 DNA-damage-inducible transcript 3 1.12973
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.11809
LEP leptin 1.11501
IL4 interleukin 4 1.1122
BAX BCL2-associated X protein 1.10459
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.10246
TGFB1 transforming growth factor, beta 1 1.09857
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.07057
SOD2 superoxide dismutase 2, mitochondrial 1.05274
MAPK9 mitogen-activated protein kinase 9 1.04941
IL12B interleukin 12B 1.03046
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.02933
MPO myeloperoxidase 1.02262
INS insulin 1.01137
PPARA peroxisome proliferator-activated receptor alpha 1.01062