Shock, Cardiogenic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012770
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Genes

129 genes/proteins associated with the disease Shock, Cardiogenic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
EPO erythropoietin 2.88009
PLAT plasminogen activator, tissue 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.18321
TNF tumor necrosis factor 2.15306
FOS FBJ murine osteosarcoma viral oncogene homolog 2.09683
MAPK1 mitogen-activated protein kinase 1 1.95178
IL6 interleukin 6 1.88836
ADRB1 adrenoceptor beta 1 1.88803
MAPK3 mitogen-activated protein kinase 3 1.83646
CAT catalase 1.79713
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.79082
BAX BCL2-associated X protein 1.78759
VEGFA vascular endothelial growth factor A 1.77335
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.73089
IL1B interleukin 1, beta 1.7183
NPPA natriuretic peptide A 1.67333
TGFB2 transforming growth factor, beta 2 1.67137
BCL2 B-cell CLL/lymphoma 2 1.66468
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.66339
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.61967
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.60454
EDN1 endothelin 1 1.59685
INS insulin 1.59661
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.57994
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.57474
HMOX1 heme oxygenase 1 1.5678
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.55871
NOS2 nitric oxide synthase 2, inducible 1.55378
TGFB1 transforming growth factor, beta 1 1.5501
TH tyrosine hydroxylase 1.54427
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.52111
SOD1 superoxide dismutase 1, soluble 1.51759
FAS Fas cell surface death receptor 1.51004
REN renin 1.50524
ADRB2 adrenoceptor beta 2, surface 1.49813
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.48068
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.46832
NPPB natriuretic peptide B 1.46067
MAPK8 mitogen-activated protein kinase 8 1.45247
MAOA monoamine oxidase A 1.43809
BCL2L1 BCL2-like 1 1.41992
SOD2 superoxide dismutase 2, mitochondrial 1.41451
IL10 interleukin 10 1.41119
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.40953
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.39869
POMC proopiomelanocortin 1.37504
COMT catechol-O-methyltransferase 1.37418
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.37332
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.37189
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.36791
EGFR epidermal growth factor receptor 1.36332
CXCL8 chemokine (C-X-C motif) ligand 8 1.3484
FASLG Fas ligand (TNF superfamily, member 6) 1.33583
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.32846
CRH corticotropin releasing hormone 1.32577
JUN jun proto-oncogene 1.32369
ADRB3 adrenoceptor beta 3 1.31208
DRD1 dopamine receptor D1 1.3103
EGR1 early growth response 1 1.29379
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.28425
DRD2 dopamine receptor D2 1.28395
IFNG interferon, gamma 1.28303
DDIT3 DNA-damage-inducible transcript 3 1.26545
BDNF brain-derived neurotrophic factor 1.26483
CREB1 cAMP responsive element binding protein 1 1.2599
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.25776
NOS1 nitric oxide synthase 1 (neuronal) 1.25463
CCL2 chemokine (C-C motif) ligand 2 1.25276
SPP1 secreted phosphoprotein 1 1.2352
JUNB jun B proto-oncogene 1.22209
G6PD glucose-6-phosphate dehydrogenase 1.21695
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 1.21271
GJA1 gap junction protein, alpha 1, 43kDa 1.21173
FGF2 fibroblast growth factor 2 (basic) 1.20784
PKM pyruvate kinase, muscle 1.20493
MAOB monoamine oxidase B 1.20493
PENK proenkephalin 1.20493
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.20328
PARP1 poly (ADP-ribose) polymerase 1 1.20262
TP53 tumor protein p53 1.19312
TAC1 tachykinin, precursor 1 1.18259
CCND3 cyclin D3 1.17993
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.17926
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.17761
CCL3 chemokine (C-C motif) ligand 3 1.16467
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.15797
MMP9 matrix metallopeptidase 9 1.1556
IGF1 insulin-like growth factor 1 (somatomedin C) 1.15324
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.15089
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.14336
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.13381
MMP2 matrix metallopeptidase 2 1.13007
ADRA1B adrenoceptor alpha 1B 1.12838
LEP leptin 1.1122
CALCA calcitonin-related polypeptide alpha 1.09927
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.08975
HSPA8 heat shock 70kDa protein 8 1.08762
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.0869
GNAS GNAS complex locus 1.08549
RYR2 ryanodine receptor 2 (cardiac) 1.08055
PTEN phosphatase and tensin homolog 1.07983
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.07947
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.07411
ORM2 orosomucoid 2 1.07057
CYCS cytochrome c, somatic 1.06188
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.05828
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.05685
PRKCE protein kinase C, epsilon 1.05535
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.05535
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.04978
THBS1 thrombospondin 1 1.04794
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.04757
TNNI3 troponin I type 3 (cardiac) 1.04389
IL1A interleukin 1, alpha 1.04276
ERP29 endoplasmic reticulum protein 29 1.04088
THY1 Thy-1 cell surface antigen 1.04088
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.04088
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.03752
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.03604
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.03419
BID BH3 interacting domain death agonist 1.03159
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03046
PRL prolactin 1.02485
PPARG peroxisome proliferator-activated receptor gamma 1.02485
NPY neuropeptide Y 1.02262
EDNRB endothelin receptor type B 1.02225
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.02077
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.01966
NUPR1 nuclear protein, transcriptional regulator, 1 1.01137