Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1739
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Genes

600 genes differentially expressed during Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 3.66903
TMEM59 transmembrane protein 59 3.21154
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.82774
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.69711
SH3BP2 SH3-domain binding protein 2 2.68714
JARID2 jumonji, AT rich interactive domain 2 2.67701
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.66948
ATPIF1 ATPase inhibitory factor 1 2.66845
ATF4 activating transcription factor 4 2.6433
FOXK2 forkhead box K2 2.38627
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.3808
GRK6 G protein-coupled receptor kinase 6 2.32664
RAB32 RAB32, member RAS oncogene family 2.31149
TPP1 tripeptidyl peptidase I 2.28558
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.27871
ORAI3 ORAI calcium release-activated calcium modulator 3 2.26975
ETFB electron-transfer-flavoprotein, beta polypeptide 2.26948
COPS3 COP9 signalosome subunit 3 2.25751
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.24823
ENSA endosulfine alpha 2.24356
GSTO1 glutathione S-transferase omega 1 2.2401
IRAK1 interleukin-1 receptor-associated kinase 1 2.22829
UQCRH ubiquinol-cytochrome c reductase hinge protein 2.18112
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.15341
ADRM1 adhesion regulating molecule 1 2.13283
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.13049
PTTG1 pituitary tumor-transforming 1 2.12972
NXF2 nuclear RNA export factor 2 2.09921
ASL argininosuccinate lyase 2.09339
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.08836
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.07968
UROD uroporphyrinogen decarboxylase 2.07517
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.05461
MAP4 microtubule-associated protein 4 2.04982
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.02727
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.00881
HDLBP high density lipoprotein binding protein 2.00326
EBP emopamil binding protein (sterol isomerase) 1.98105
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.97707
MIA melanoma inhibitory activity 1.96504
PTGES prostaglandin E synthase 1.96347
C1S complement component 1, s subcomponent 1.9562
MED16 mediator complex subunit 16 1.9463
PPIF peptidylprolyl isomerase F 1.93995
TALDO1 transaldolase 1 1.92616
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.92471
BCL2L2 BCL2-like 2 1.91221
PARK7 parkinson protein 7 1.88551
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 1.87958
CA11 carbonic anhydrase XI 1.87703
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 1.86713
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.86297
SRI sorcin 1.84233
TNK2 tyrosine kinase, non-receptor, 2 1.84082
TARBP2 TAR (HIV-1) RNA binding protein 2 1.83772
C20ORF24 chromosome 20 open reading frame 24 1.83702
DUSP13 dual specificity phosphatase 13 1.83479
DUSP22 dual specificity phosphatase 22 1.83386
RGS19 regulator of G-protein signaling 19 1.83172
HMGN2 high mobility group nucleosomal binding domain 2 1.82988
COX5B cytochrome c oxidase subunit Vb 1.82912
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 1.82116
CPNE7 copine VII 1.81479
BCKDK branched chain ketoacid dehydrogenase kinase 1.7917
ADRA2C adrenoceptor alpha 2C 1.78533
SUCLG1 succinate-CoA ligase, alpha subunit 1.77864
GSK3B glycogen synthase kinase 3 beta 1.74194
TBL1X transducin (beta)-like 1X-linked 1.73826
ACTA2 actin, alpha 2, smooth muscle, aorta 1.73442
ADCY10P1 adenylate cyclase 10 (soluble) pseudogene 1 1.73256
TROVE2 TROVE domain family, member 2 1.72358
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.7228
ACAA1 acetyl-CoA acyltransferase 1 1.72061
HSPG2 heparan sulfate proteoglycan 2 1.71959
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.71487
CCNI cyclin I 1.68541
RPL36AL ribosomal protein L36a-like 1.6854
MYO9B myosin IXB 1.67941
RPN1 ribophorin I 1.67
ANXA1 annexin A1 1.66854
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.66584
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.66336
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.65997
SPAG8 sperm associated antigen 8 1.65745
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.65481
SCGN secretagogin, EF-hand calcium binding protein 1.65315
TXN thioredoxin 1.65246
PDIA4 protein disulfide isomerase family A, member 4 1.65021
FGF14 fibroblast growth factor 14 1.63926
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.63665
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.62512
STAG3 stromal antigen 3 1.62079
TAL1 T-cell acute lymphocytic leukemia 1 1.61806
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.61354
TST thiosulfate sulfurtransferase (rhodanese) 1.61332
IL13RA1 interleukin 13 receptor, alpha 1 1.61157
CDK16 cyclin-dependent kinase 16 1.60835
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.60452
GUSB glucuronidase, beta 1.59998
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.59963
CCNB2 cyclin B2 1.59918
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 1.59881
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.59037
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 1.58134
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 1.578
ARSA arylsulfatase A 1.56309
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.56169
EMD emerin 1.56162
CXCL9 chemokine (C-X-C motif) ligand 9 1.56122
FOXO3 forkhead box O3 1.55773
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.55763
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.55744
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 1.54539
NRD1 nardilysin (N-arginine dibasic convertase) 1.52931
RNF17 ring finger protein 17 1.5237
FANCI Fanconi anemia, complementation group I 1.5215
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.51596
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.50486
RTN4 reticulon 4 1.50448
LDLR low density lipoprotein receptor 1.5028
GP1BA glycoprotein Ib (platelet), alpha polypeptide 1.50194
CENPF centromere protein F, 350/400kDa 1.50147
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.50139
HIST1H2BF histone cluster 1, H2bf 1.50075
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 1.49175
CHMP1A charged multivesicular body protein 1A 1.4898
MAPK10 mitogen-activated protein kinase 10 1.48538
CHP2 calcineurin-like EF-hand protein 2 1.47373
MGMT O-6-methylguanine-DNA methyltransferase 1.47299
PREB prolactin regulatory element binding 1.47207
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.46768
MAGEB4 melanoma antigen family B4 1.46657
WSB2 WD repeat and SOCS box containing 2 1.46512
TWF2 twinfilin actin binding protein 2 1.45348
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.45269
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.44955
LPL lipoprotein lipase 1.44933
MEA1 male-enhanced antigen 1 1.44836
KATNB1 katanin p80 (WD repeat containing) subunit B 1 1.44803
ACTG1 actin gamma 1 1.44795
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 1.44529
B9D1 B9 protein domain 1 1.44406
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.43693
GADD45B growth arrest and DNA-damage-inducible, beta 1.43644
PRSS3 protease, serine, 3 1.43375
PDGFC platelet derived growth factor C 1.42864
HPS1 Hermansky-Pudlak syndrome 1 1.42667
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.42459
ALX1 ALX homeobox 1 1.42368
MPST mercaptopyruvate sulfurtransferase 1.41448
HEXB hexosaminidase B (beta polypeptide) 1.41157
COX7B cytochrome c oxidase subunit VIIb 1.40819
FHOD1 formin homology 2 domain containing 1 1.39684
EPAS1 endothelial PAS domain protein 1 1.39482
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.39394
LTA4H leukotriene A4 hydrolase 1.38595
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 1.38493
VCAN versican 1.38414
DMBT1 deleted in malignant brain tumors 1 1.37905
DAZAP1 DAZ associated protein 1 1.37831
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C 1.37798
HIST2H2BE histone cluster 2, H2be 1.37478
DCTN2 dynactin 2 (p50) 1.37463
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.37314
KLK10 kallikrein-related peptidase 10 1.3717
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 1.36763
TFF3 trefoil factor 3 (intestinal) 1.36723
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.36214
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.35363
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 1.35212
GCK glucokinase (hexokinase 4) 1.34789
COL10A1 collagen, type X, alpha 1 1.34739
TWF1 twinfilin actin binding protein 1 1.3456
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.34033
HIST1H2BK histone cluster 1, H2bk 1.33772
TRAIP TRAF interacting protein 1.33594
RAB13 RAB13, member RAS oncogene family 1.33201
TAGLN3 transgelin 3 1.32821
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.32807
HEBP2 heme binding protein 2 1.32715
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 1.32294
HIST1H2BB histone cluster 1, H2bb 1.32243
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 1.32137
WASF2 WAS protein family, member 2 1.3195
MYBPC1 myosin binding protein C, slow type 1.31551
USF2 upstream transcription factor 2, c-fos interacting 1.31515
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.31273
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 1.30909
TMEM192 transmembrane protein 192 1.30877
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.30792
SCPEP1 serine carboxypeptidase 1 1.30657
FADS1 fatty acid desaturase 1 1.30545
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.29932
IMMT inner membrane protein, mitochondrial 1.29802
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.29793
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 1.29624
PGAM1 phosphoglycerate mutase 1 (brain) 1.29537
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 1.29267
FURIN furin (paired basic amino acid cleaving enzyme) 1.29254
NSD1 nuclear receptor binding SET domain protein 1 1.28756
NDC80 NDC80 kinetochore complex component 1.28702
CABP1 calcium binding protein 1 1.28661
VAMP3 vesicle-associated membrane protein 3 1.28477
NPM3 nucleophosmin/nucleoplasmin 3 1.28411
IER3 immediate early response 3 1.28362
PRRX1 paired related homeobox 1 1.28105
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.2798
FASN fatty acid synthase 1.27922
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.27915
HOXB1 homeobox B1 1.27435
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.27428
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 1.27135
TK1 thymidine kinase 1, soluble 1.26772
AMBP alpha-1-microglobulin/bikunin precursor 1.26698
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 1.26458
SIRT5 sirtuin 5 1.26432
FGFBP1 fibroblast growth factor binding protein 1 1.26129
SH3GL1 SH3-domain GRB2-like 1 1.25947
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.25592
C1R complement component 1, r subcomponent 1.25563
SURF1 surfeit 1 1.2553
MXRA7 matrix-remodelling associated 7 1.25241
LTBP1 latent transforming growth factor beta binding protein 1 1.25102
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1.24948
RPS28 ribosomal protein S28 1.2484
EGR1 early growth response 1 1.24787
NCAPG non-SMC condensin I complex, subunit G 1.24766
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.24699
CREB3 cAMP responsive element binding protein 3 1.24626
CRAT carnitine O-acetyltransferase 1.24593
H2BFS H2B histone family, member S (pseudogene) 1.24571
GAS7 growth arrest-specific 7 1.24416
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.24416
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.24171
BIRC5 baculoviral IAP repeat containing 5 1.24087
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.23669
LARP1 La ribonucleoprotein domain family, member 1 1.23642
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 1.23552
BATF basic leucine zipper transcription factor, ATF-like 1.23383
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.23246
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.23043
KCMF1 potassium channel modulatory factor 1 1.22985
TGFB3 transforming growth factor, beta 3 1.22958
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.22941
VCL vinculin 1.22804
LMNA lamin A/C 1.22732
UBE2C ubiquitin-conjugating enzyme E2C 1.22459
SNN stannin 1.22346
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.22082
SPINK1 serine peptidase inhibitor, Kazal type 1 1.21956
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.219
C3AR1 complement component 3a receptor 1 1.21837
AFF3 AF4/FMR2 family, member 3 1.21693
RNASE3 ribonuclease, RNase A family, 3 1.21664
EIF1 eukaryotic translation initiation factor 1 1.21226
MRPL17 mitochondrial ribosomal protein L17 1.21215
CAPZB capping protein (actin filament) muscle Z-line, beta 1.21122
EDA2R ectodysplasin A2 receptor 1.2108
CENPE centromere protein E, 312kDa 1.20967
COASY CoA synthase 1.20933
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.2091
TRAFD1 TRAF-type zinc finger domain containing 1 1.20856
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.20299
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.19853
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.19727
BCL7B B-cell CLL/lymphoma 7B 1.19667
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.1955
CDKN3 cyclin-dependent kinase inhibitor 3 1.19453
AP1B1 adaptor-related protein complex 1, beta 1 subunit 1.18988
SEC13 SEC13 homolog (S. cerevisiae) 1.18949
FXYD6 FXYD domain containing ion transport regulator 6 1.1885
RBMS3 RNA binding motif, single stranded interacting protein 3 1.18575
SPHK1 sphingosine kinase 1 1.18574
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.18036
CTSZ cathepsin Z 1.17985
SLC26A10 solute carrier family 26, member 10 1.17822
RGS6 regulator of G-protein signaling 6 1.17288
PHGDH phosphoglycerate dehydrogenase 1.17176
CLTA clathrin, light chain A 1.17108
VRK1 vaccinia related kinase 1 1.16601
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.16369
GLA galactosidase, alpha 1.16193
GLRX glutaredoxin (thioltransferase) 1.16104
GPR42 G protein-coupled receptor 42 (gene/pseudogene) 1.15596
UBL4A ubiquitin-like 4A 1.15004
HIST1H4E histone cluster 1, H4e 1.14971
ZNF580 zinc finger protein 580 1.14557
DGKD diacylglycerol kinase, delta 130kDa 1.14531
ZNF593 zinc finger protein 593 1.14477
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.1443
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.14422
HLX H2.0-like homeobox 1.14418
SYNGR1 synaptogyrin 1 1.14393
CNOT3 CCR4-NOT transcription complex, subunit 3 1.14261
RRM2 ribonucleotide reductase M2 1.14065
C1QL1 complement component 1, q subcomponent-like 1 1.13923
MYCNOS MYCN opposite strand 1.13903
LAMP1 lysosomal-associated membrane protein 1 1.13545
CCNT1 cyclin T1 1.13522
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.1333

decreased expression

Symbol Name Standardized Value
RNFT1 ring finger protein, transmembrane 1 -3.62742
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -3.5552
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -3.32154
MUTYH mutY homolog -3.30697
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -3.24848
USP9X ubiquitin specific peptidase 9, X-linked -3.20726
RHOQ ras homolog family member Q -3.10689
TMOD3 tropomodulin 3 (ubiquitous) -2.99798
CREBL2 cAMP responsive element binding protein-like 2 -2.99522
NFX1 nuclear transcription factor, X-box binding 1 -2.98444
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.91213
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.89075
TRAPPC3 trafficking protein particle complex 3 -2.88598
RAB14 RAB14, member RAS oncogene family -2.87723
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.85
ANXA7 annexin A7 -2.83972
MLH1 mutL homolog 1 -2.82219
PRDX3 peroxiredoxin 3 -2.80508
CAPRIN1 cell cycle associated protein 1 -2.79741
SEP15 15 kDa selenoprotein -2.78431
APOL6 apolipoprotein L, 6 -2.77293
TUBD1 tubulin, delta 1 -2.76673
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.76562
CASP2 caspase 2, apoptosis-related cysteine peptidase -2.75286
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.75159
GLUD2 glutamate dehydrogenase 2 -2.749
ANAPC5 anaphase promoting complex subunit 5 -2.73485
FLI1 Fli-1 proto-oncogene, ETS transcription factor -2.71149
YME1L1 YME1-like 1 ATPase -2.70998
CRLF3 cytokine receptor-like factor 3 -2.67172
USP8 ubiquitin specific peptidase 8 -2.66768
ATG5 autophagy related 5 -2.63636
PRPF18 pre-mRNA processing factor 18 -2.6333
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.62506
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.58594
NFRKB nuclear factor related to kappaB binding protein -2.58328
CD164 CD164 molecule, sialomucin -2.58168
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -2.56508
UST uronyl-2-sulfotransferase -2.5603
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.52396
PFKM phosphofructokinase, muscle -2.52322
ECD ecdysoneless homolog (Drosophila) -2.51781
MSH3 mutS homolog 3 -2.5108
NDFIP1 Nedd4 family interacting protein 1 -2.50054
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -2.4914
SMAD4 SMAD family member 4 -2.4722
WDR61 WD repeat domain 61 -2.46227
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -2.44655
LIN7C lin-7 homolog C (C. elegans) -2.44411
MED14 mediator complex subunit 14 -2.42796
GCLC glutamate-cysteine ligase, catalytic subunit -2.42527
SOAT1 sterol O-acyltransferase 1 -2.41219
EDAR ectodysplasin A receptor -2.41102
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.40759
CDC27 cell division cycle 27 -2.39397
RASA3 RAS p21 protein activator 3 -2.39371
CCDC6 coiled-coil domain containing 6 -2.39026
RSL24D1 ribosomal L24 domain containing 1 -2.37824
ARNTL aryl hydrocarbon receptor nuclear translocator-like -2.36649
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -2.36317
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.36175
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.36052
FOXO1 forkhead box O1 -2.35247
CLDND1 claudin domain containing 1 -2.3474
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.34505
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -2.33828
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.336
CALCOCO2 calcium binding and coiled-coil domain 2 -2.33011
MSH6 mutS homolog 6 -2.32719
RPP14 ribonuclease P/MRP 14kDa subunit -2.31579
TFCP2 transcription factor CP2 -2.3102
DLD dihydrolipoamide dehydrogenase -2.30877
IPP intracisternal A particle-promoted polypeptide -2.30855
U2AF2 U2 small nuclear RNA auxiliary factor 2 -2.30778
NDRG3 NDRG family member 3 -2.30223
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.29228
ARFIP1 ADP-ribosylation factor interacting protein 1 -2.28643
CREBZF CREB/ATF bZIP transcription factor -2.27885
CROT carnitine O-octanoyltransferase -2.2646
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -2.26166
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 -2.2604
BIRC3 baculoviral IAP repeat containing 3 -2.25936
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.25613
CHD1 chromodomain helicase DNA binding protein 1 -2.25254
STAT2 signal transducer and activator of transcription 2, 113kDa -2.23411
LVRN laeverin -2.23096
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -2.22832
MAT2B methionine adenosyltransferase II, beta -2.22474
KRIT1 KRIT1, ankyrin repeat containing -2.20804
PAX8 paired box 8 -2.20764
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -2.20375
SESN1 sestrin 1 -2.20304
ZMYM4 zinc finger, MYM-type 4 -2.19354
ZBTB11 zinc finger and BTB domain containing 11 -2.19017
GDE1 glycerophosphodiester phosphodiesterase 1 -2.18726
PAWR PRKC, apoptosis, WT1, regulator -2.1781
FMO5 flavin containing monooxygenase 5 -2.17773
UBE4B ubiquitination factor E4B -2.16952
JAK3 Janus kinase 3 -2.16668
IGHMBP2 immunoglobulin mu binding protein 2 -2.15032
ITGA6 integrin, alpha 6 -2.14826
SS18 synovial sarcoma translocation, chromosome 18 -2.1468
POLB polymerase (DNA directed), beta -2.14521
EML4 echinoderm microtubule associated protein like 4 -2.14242
SMAD3 SMAD family member 3 -2.14135
EIF1AX eukaryotic translation initiation factor 1A, X-linked -2.13559
RNF14 ring finger protein 14 -2.13394
CSNK1A1 casein kinase 1, alpha 1 -2.13369
FSTL1 follistatin-like 1 -2.12023
HBS1L HBS1-like translational GTPase -2.11875
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.10744
SYPL1 synaptophysin-like 1 -2.1047
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -2.10377
ZNF207 zinc finger protein 207 -2.10305
FLT4 fms-related tyrosine kinase 4 -2.09705
UBTF upstream binding transcription factor, RNA polymerase I -2.09027
KAT2A K(lysine) acetyltransferase 2A -2.087
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -2.08248
ATF2 activating transcription factor 2 -2.08112
TMPO thymopoietin -2.08079
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.07989
BTN2A2 butyrophilin, subfamily 2, member A2 -2.06892
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.06888
NFYA nuclear transcription factor Y, alpha -2.06665
ZNF263 zinc finger protein 263 -2.06579
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -2.06538
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.03812
HDAC6 histone deacetylase 6 -2.035
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -2.03417
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.0298
KIF2A kinesin heavy chain member 2A -2.02717
ORC4 origin recognition complex, subunit 4 -2.02363
USP16 ubiquitin specific peptidase 16 -2.02262
COPS5 COP9 signalosome subunit 5 -2.02152
IL16 interleukin 16 -2.01751
TOMM34 translocase of outer mitochondrial membrane 34 -2.01566
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.01422
MTRF1 mitochondrial translational release factor 1 -2.01072
ATG12 autophagy related 12 -2.00432
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.99915
MED17 mediator complex subunit 17 -1.99131
TTN titin -1.98629
NMT2 N-myristoyltransferase 2 -1.98351
PPID peptidylprolyl isomerase D -1.97559
RABGGTB Rab geranylgeranyltransferase, beta subunit -1.97501
ZNF7 zinc finger protein 7 -1.96713
GDF9 growth differentiation factor 9 -1.96517
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.96506
COG2 component of oligomeric golgi complex 2 -1.96268
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.95818
TNNC1 troponin C type 1 (slow) -1.95664
KATNA1 katanin p60 (ATPase containing) subunit A 1 -1.95384
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -1.95359
ZNF200 zinc finger protein 200 -1.95268
CRBN cereblon -1.95058
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.94429
BCAP29 B-cell receptor-associated protein 29 -1.94248
PBX3 pre-B-cell leukemia homeobox 3 -1.94096
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -1.93431
SIRT1 sirtuin 1 -1.92989
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.92719
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -1.91838
TGIF2 TGFB-induced factor homeobox 2 -1.91583
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.90882
ZNF117 zinc finger protein 117 -1.90869
CASP8AP2 caspase 8 associated protein 2 -1.90742
RNF6 ring finger protein (C3H2C3 type) 6 -1.90707
IVD isovaleryl-CoA dehydrogenase -1.90644
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -1.89703
RSRC2 arginine/serine-rich coiled-coil 2 -1.89702
TNK1 tyrosine kinase, non-receptor, 1 -1.89529
TBCC tubulin folding cofactor C -1.89505
ZNF274 zinc finger protein 274 -1.89104
KIF22 kinesin family member 22 -1.8898
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -1.88675
N4BP3 NEDD4 binding protein 3 -1.87905
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.87877
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -1.86579
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.86535
LTB lymphotoxin beta (TNF superfamily, member 3) -1.86451
CDC40 cell division cycle 40 -1.86422
GOSR2 golgi SNAP receptor complex member 2 -1.86259
RAB2A RAB2A, member RAS oncogene family -1.8625
NELL2 NEL-like 2 (chicken) -1.84838
FBXO3 F-box protein 3 -1.84099
KAT7 K(lysine) acetyltransferase 7 -1.8404
USPL1 ubiquitin specific peptidase like 1 -1.83894
POPDC2 popeye domain containing 2 -1.83573
ZNF224 zinc finger protein 224 -1.83451
PNO1 partner of NOB1 homolog (S. cerevisiae) -1.83327
PEX11B peroxisomal biogenesis factor 11 beta -1.83105
TSPAN31 tetraspanin 31 -1.83084
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -1.83046
OXA1L oxidase (cytochrome c) assembly 1-like -1.82806
PRPF4 pre-mRNA processing factor 4 -1.82692
GLE1 GLE1 RNA export mediator -1.8252
BRD8 bromodomain containing 8 -1.82254
HHEX hematopoietically expressed homeobox -1.82047
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.81814
NRF1 nuclear respiratory factor 1 -1.81396
IKZF1 IKAROS family zinc finger 1 (Ikaros) -1.8112
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -1.81051
TXK TXK tyrosine kinase -1.80741
KPNB1 karyopherin (importin) beta 1 -1.80668
HP1BP3 heterochromatin protein 1, binding protein 3 -1.80211
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -1.80057
CASP8 caspase 8, apoptosis-related cysteine peptidase -1.79907
LEMD3 LEM domain containing 3 -1.79692
RAB8B RAB8B, member RAS oncogene family -1.79424
CCHCR1 coiled-coil alpha-helical rod protein 1 -1.78971
GTF2B general transcription factor IIB -1.78551
OSBP oxysterol binding protein -1.78439
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -1.78372
DGKA diacylglycerol kinase, alpha 80kDa -1.78364
ZNF85 zinc finger protein 85 -1.78235
MED23 mediator complex subunit 23 -1.77912
CUL4B cullin 4B -1.77591
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -1.77295
DIDO1 death inducer-obliterator 1 -1.76821
DGKG diacylglycerol kinase, gamma 90kDa -1.76193
TCEA2 transcription elongation factor A (SII), 2 -1.76172
PDE4B phosphodiesterase 4B, cAMP-specific -1.76027
TACC1 transforming, acidic coiled-coil containing protein 1 -1.75871
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.75576
ATF7 activating transcription factor 7 -1.7501
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -1.74976
IKZF3 IKAROS family zinc finger 3 (Aiolos) -1.74419
DCTN4 dynactin 4 (p62) -1.74086
CCL8 chemokine (C-C motif) ligand 8 -1.74041
NFS1 NFS1 cysteine desulfurase -1.74005
NFYB nuclear transcription factor Y, beta -1.73352
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -1.7317
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -1.73154
CPA2 carboxypeptidase A2 (pancreatic) -1.72827
GMCL1 germ cell-less, spermatogenesis associated 1 -1.72634
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -1.72554
GOLGA4 golgin A4 -1.72182
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -1.72092
MARS methionyl-tRNA synthetase -1.71752
CAMK4 calcium/calmodulin-dependent protein kinase IV -1.7145
CANX calnexin -1.71425
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.71345
TGDS TDP-glucose 4,6-dehydratase -1.71254
USO1 USO1 vesicle transport factor -1.71245
CASP10 caspase 10, apoptosis-related cysteine peptidase -1.71104
STK4 serine/threonine kinase 4 -1.70876
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -1.7072
FUBP1 far upstream element (FUSE) binding protein 1 -1.70529
NIT1 nitrilase 1 -1.70515
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -1.69622
SSBP1 single-stranded DNA binding protein 1, mitochondrial -1.69379
PSIP1 PC4 and SFRS1 interacting protein 1 -1.69136
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.69119
GSR glutathione reductase -1.69055
CETN3 centrin, EF-hand protein, 3 -1.68994
FOXN2 forkhead box N2 -1.68889
FCRL2 Fc receptor-like 2 -1.68747
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.68104
SUMO1 small ubiquitin-like modifier 1 -1.67735
ZFX zinc finger protein, X-linked -1.67426
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -1.6705
ACSM3 acyl-CoA synthetase medium-chain family member 3 -1.67039
ZNF225 zinc finger protein 225 -1.66624
TARDBP TAR DNA binding protein -1.65838
LINC01565 long intergenic non-protein coding RNA 1565 -1.6569
PEX12 peroxisomal biogenesis factor 12 -1.65659
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -1.65144
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.64746
RPA1 replication protein A1, 70kDa -1.64695
RBM15B RNA binding motif protein 15B -1.64469
MED6 mediator complex subunit 6 -1.64421
EIF4B eukaryotic translation initiation factor 4B -1.64237
PIAS1 protein inhibitor of activated STAT, 1 -1.64236
BAG3 BCL2-associated athanogene 3 -1.64082
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -1.63993
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -1.63969
HSF2 heat shock transcription factor 2 -1.63844
RBM3 RNA binding motif (RNP1, RRM) protein 3 -1.63338
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa -1.63307
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.63291
PUM2 pumilio RNA-binding family member 2 -1.62951
SRPR signal recognition particle receptor (docking protein) -1.6272
MOCS3 molybdenum cofactor synthesis 3 -1.62698
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -1.62489
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.62483
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -1.62408
CDK3 cyclin-dependent kinase 3 -1.6219
NKRF NFKB repressing factor -1.62059
CTSO cathepsin O -1.62018
INSL4 insulin-like 4 (placenta) -1.61955
HBP1 HMG-box transcription factor 1 -1.61428
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -1.61353
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -1.61341
TUBGCP4 tubulin, gamma complex associated protein 4 -1.61268
SLAMF1 signaling lymphocytic activation molecule family member 1 -1.60868
NR3C2 nuclear receptor subfamily 3, group C, member 2 -1.60739
CRYBB2 crystallin, beta B2 -1.6053
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -1.6052
PRKD3 protein kinase D3 -1.60074
CDH7 cadherin 7, type 2 -1.5992