Severe Acute Respiratory Syndrome Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A viral infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia. (Human Disease Ontology, DOID_2945)
Similar Terms
Downloads & Tools

Genes

41 genes associated with the Severe Acute Respiratory Syndrome phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AHSG alpha-2-HS-glycoprotein
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD209 CD209 molecule
CLEC4G C-type lectin domain family 4, member G
CLEC4M C-type lectin domain family 4, member M
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL9 chemokine (C-X-C motif) ligand 9
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGL2 fibrinogen-like 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
ICAM3 intercellular adhesion molecule 3
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL10 interleukin 10
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MX1 MX dynamin-like GTPase 1
NOS3 nitric oxide synthase 3 (endothelial cell)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TNF tumor necrosis factor