Serotonin Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D020230
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Genes

66 genes/proteins associated with the disease Serotonin Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.27323
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.20354
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.01924
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.00398
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.97954
BDNF brain-derived neurotrophic factor 1.87775
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.77121
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.76462
PRL prolactin 1.73048
DRD2 dopamine receptor D2 1.72405
FOS FBJ murine osteosarcoma viral oncogene homolog 1.72302
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.70615
FNDC4 fibronectin type III domain containing 4 1.67462
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.59849
MAPK1 mitogen-activated protein kinase 1 1.54208
TNF tumor necrosis factor 1.5143
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.507
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.50198
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.5012
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.48068
MAPK3 mitogen-activated protein kinase 3 1.46781
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.46146
DRD1 dopamine receptor D1 1.44599
HPN hepsin 1.44001
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.39841
CAT catalase 1.39507
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.38891
POMC proopiomelanocortin 1.38213
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.37846
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.34198
FABP1 fatty acid binding protein 1, liver 1.33701
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.31357
NUPR1 nuclear protein, transcriptional regulator, 1 1.30788
INHBE inhibin, beta E 1.30451
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.28058
TAGLN transgelin 1.2456
C10ORF10 chromosome 10 open reading frame 10 1.24213
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.23899
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.23552
EGR1 early growth response 1 1.18159
OPRM1 opioid receptor, mu 1 1.17761
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.17728
MAOA monoamine oxidase A 1.17431
ARC activity-regulated cytoskeleton-associated protein 1.16799
CYP3A cytochrome P450, family 3, subfamily A 1.16799
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.16766
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.15695
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.15223
CREB1 cAMP responsive element binding protein 1 1.13862
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.12014
VEGFA vascular endothelial growth factor A 1.11501
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.10942
CDK5 cyclin-dependent kinase 5 1.10631
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.08904
SOD1 superoxide dismutase 1, soluble 1.08868
BAX BCL2-associated X protein 1.08196
CPPED1 calcineurin-like phosphoesterase domain containing 1 1.07911
IL6 interleukin 6 1.0766
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.06515
PENK proenkephalin 1.059
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.04163
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.04163
CRH corticotropin releasing hormone 1.04014
BCL2 B-cell CLL/lymphoma 2 1.03009
DCAF8 DDB1 and CUL4 associated factor 8 1.02522
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.02336