Sepsis_Hepatic Tissue_GSE1781 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1781
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Genes

600 genes differentially expressed during Sepsis_Hepatic Tissue_GSE1781 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
AHSG alpha-2-HS-glycoprotein 5.05182
PTTG1IP pituitary tumor-transforming 1 interacting protein 4.79726
SUOX sulfite oxidase 4.43015
MCFD2 multiple coagulation factor deficiency 2 3.86185
F2 coagulation factor II (thrombin) 3.6799
GSTA3 glutathione S-transferase alpha 3 3.62905
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 3.60731
GAMT guanidinoacetate N-methyltransferase 3.53859
HPN hepsin 3.35417
ANXA11 annexin A11 3.28883
CETN2 centrin, EF-hand protein, 2 3.28077
ZDHHC4 zinc finger, DHHC-type containing 4 3.12734
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 3.07969
SDF4 stromal cell derived factor 4 2.88546
F10 coagulation factor X 2.76381
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.72005
CTSB cathepsin B 2.69621
PPIF peptidylprolyl isomerase F 2.68366
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.64727
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 2.55543
RPS2 ribosomal protein S2 2.54356
FTH1 ferritin, heavy polypeptide 1 2.44383
PEBP1 phosphatidylethanolamine binding protein 1 2.4426
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.43291
MDH1 malate dehydrogenase 1, NAD (soluble) 2.41403
TXN2 thioredoxin 2 2.39501
TPI1 triosephosphate isomerase 1 2.3879
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.38327
TMCC2 transmembrane and coiled-coil domain family 2 2.36367
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.31994
FGG fibrinogen gamma chain 2.30485
MRPS28 mitochondrial ribosomal protein S28 2.26973
ESD esterase D 2.26061
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.24839
C8B complement component 8, beta polypeptide 2.24694
MRPL53 mitochondrial ribosomal protein L53 2.24141
COL18A1 collagen, type XVIII, alpha 1 2.23177
APOA2 apolipoprotein A-II 2.22026
AMD1 adenosylmethionine decarboxylase 1 2.20869
HPX hemopexin 2.18925
ND1 2.14646
NTF3 neurotrophin 3 2.14114
EMC3 ER membrane protein complex subunit 3 2.13366
APOA1 apolipoprotein A-I 2.08846
TMEM126B transmembrane protein 126B 2.07799
MST1 macrophage stimulating 1 2.06103
GSTO1 glutathione S-transferase omega 1 2.05978
GPR146 G protein-coupled receptor 146 2.04333
CFL2 cofilin 2 (muscle) 2.03535
TTPA tocopherol (alpha) transfer protein 2.0186
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.01855
RPS20 ribosomal protein S20 2.01239
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.96424
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.94459
C3 complement component 3 1.91971
STK38 serine/threonine kinase 38 1.9106
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 1.9044
YTHDC1 YTH domain containing 1 1.88256
SIRT3 sirtuin 3 1.88132
RPS16 ribosomal protein S16 1.86725
TRA2B transformer 2 beta homolog (Drosophila) 1.85902
HOOK1 hook microtubule-tethering protein 1 1.82496
RTN3 reticulon 3 1.81403
RPS21 ribosomal protein S21 1.79292
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.76127
PDHB pyruvate dehydrogenase (lipoamide) beta 1.75957
RNF7 ring finger protein 7 1.75804
YIPF1 Yip1 domain family, member 1 1.73521
TTR transthyretin 1.73482
SNAP23 synaptosomal-associated protein, 23kDa 1.71928
HP haptoglobin 1.69481
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 1.6651
OAZ1 ornithine decarboxylase antizyme 1 1.6298
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.62676
TTC19 tetratricopeptide repeat domain 19 1.61892
SNX16 sorting nexin 16 1.61273
TST thiosulfate sulfurtransferase (rhodanese) 1.60965
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1.59296
TMEM128 transmembrane protein 128 1.58993
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.58912
ELL2 elongation factor, RNA polymerase II, 2 1.58241
QPRT quinolinate phosphoribosyltransferase 1.581
AUP1 ancient ubiquitous protein 1 1.58055
AHCYL1 adenosylhomocysteinase-like 1 1.56318
EIF4H eukaryotic translation initiation factor 4H 1.55416
TBPL1 TBP-like 1 1.55401
MARC2 mitochondrial amidoxime reducing component 2 1.54732
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.5438
WBP1L WW domain binding protein 1-like 1.54153
CCNH cyclin H 1.53696
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 1.52956
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.52678
TSPAN14 tetraspanin 14 1.52482
CFB complement factor B 1.51074
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.50192
FUCA1 fucosidase, alpha-L- 1, tissue 1.48224
CD81 CD81 molecule 1.47891
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.4761
MGST1 microsomal glutathione S-transferase 1 1.47006
TOLLIP toll interacting protein 1.4649
AMBP alpha-1-microglobulin/bikunin precursor 1.44943
DDRGK1 DDRGK domain containing 1 1.44771
INPP5F inositol polyphosphate-5-phosphatase F 1.4412
GM2A GM2 ganglioside activator 1.4278
UQCRB ubiquinol-cytochrome c reductase binding protein 1.42641
EMC10 ER membrane protein complex subunit 10 1.42006
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 1.41797
CTSH cathepsin H 1.41656
PCOLCE procollagen C-endopeptidase enhancer 1.41219
ALOX15 arachidonate 15-lipoxygenase 1.41
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.40839
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 1.3977
BSG basigin (Ok blood group) 1.39674
RPS5 ribosomal protein S5 1.39559
LCN2 lipocalin 2 1.3933
GPNMB glycoprotein (transmembrane) nmb 1.39197
COX1 1.38829
GSTZ1 glutathione S-transferase zeta 1 1.37037
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.36899
CRIPT cysteine-rich PDZ-binding protein 1.36741
IP6K1 inositol hexakisphosphate kinase 1 1.3312
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.32847
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.32834
SETD3 SET domain containing 3 1.32247
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.31554
RIPK3 receptor-interacting serine-threonine kinase 3 1.31334
TTC13 tetratricopeptide repeat domain 13 1.30853
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.30819
TMEM176B transmembrane protein 176B 1.30549
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.30472
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.30146
MYADM myeloid-associated differentiation marker 1.29491
SERTAD2 SERTA domain containing 2 1.28791
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 1.2811
GC group-specific component (vitamin D binding protein) 1.27576
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1.26553
RNASE4 ribonuclease, RNase A family, 4 1.25723
PLBD1 phospholipase B domain containing 1 1.25393
RAB1A RAB1A, member RAS oncogene family 1.25298
AADAC arylacetamide deacetylase 1.24038
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.24002
IL16 interleukin 16 1.23724
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.23535
PRDX1 peroxiredoxin 1 1.23389
PKDCC protein kinase domain containing, cytoplasmic 1.23329
APOH apolipoprotein H (beta-2-glycoprotein I) 1.23311
ACSL1 acyl-CoA synthetase long-chain family member 1 1.22131
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 1.21805
C1D C1D nuclear receptor corepressor 1.21626
TMEM42 transmembrane protein 42 1.21557
IPO11 importin 11 1.2105
MBD2 methyl-CpG binding domain protein 2 1.20213
COX7B cytochrome c oxidase subunit VIIb 1.19211
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 1.192
PMVK phosphomevalonate kinase 1.18196
ZC3H11A zinc finger CCCH-type containing 11A 1.1736
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 1.1719
SLC30A4 solute carrier family 30 (zinc transporter), member 4 1.16727
SFTPC surfactant protein C 1.16259
EBAG9 estrogen receptor binding site associated, antigen, 9 1.16002
CHUK conserved helix-loop-helix ubiquitous kinase 1.15884
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.15505
CFI complement factor I 1.15477
ALB albumin 1.15332
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.15242
MT-ND2 MTND2 1.14816
MT-ND3 NADH dehydrogenase, subunit 3 (complex I) 1.1469
VTN vitronectin 1.14434
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.13947
TDP2 tyrosyl-DNA phosphodiesterase 2 1.13786
SRR serine racemase 1.13757
KLHL9 kelch-like family member 9 1.13351
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.13239
TSPAN31 tetraspanin 31 1.12381
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 1.1224
TRAF3 TNF receptor-associated factor 3 1.11867
CYSLTR1 cysteinyl leukotriene receptor 1 1.11867
NDUFA4 NDUFA4, mitochondrial complex associated 1.11195
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.11148
FETUB fetuin B 1.10633
FOXA3 forkhead box A3 1.09083
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.08433
ALDOB aldolase B, fructose-bisphosphate 1.08125
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 1.07826
SRPR signal recognition particle receptor (docking protein) 1.07447
GCHFR GTP cyclohydrolase I feedback regulator 1.07343
TPT1 tumor protein, translationally-controlled 1 1.06481
MGST2 microsomal glutathione S-transferase 2 1.06226
ZNF519 zinc finger protein 519 1.06187
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 1.06045
SLC38A4 solute carrier family 38, member 4 1.05444
ASS1 argininosuccinate synthase 1 1.05033
ASGR1 asialoglycoprotein receptor 1 1.04822
STARD10 StAR-related lipid transfer (START) domain containing 10 1.04801
MRPS36 mitochondrial ribosomal protein S36 1.0467
CPB2 carboxypeptidase B2 (plasma) 1.04489
RHOBTB3 Rho-related BTB domain containing 3 1.04411
HPD 4-hydroxyphenylpyruvate dioxygenase 1.04021
PAIP2 poly(A) binding protein interacting protein 2 1.02987
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.02851
SETD6 SET domain containing 6 1.02599
ACSL5 acyl-CoA synthetase long-chain family member 5 1.01812
USP20 ubiquitin specific peptidase 20 1.01799
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.01523
PGP phosphoglycolate phosphatase 1.01494
TMX4 thioredoxin-related transmembrane protein 4 1.01432
ETF1 eukaryotic translation termination factor 1 1.01108
CDC20 cell division cycle 20 1.00754
RGN regucalcin 1.00116
C1GALT1C1 C1GALT1-specific chaperone 1 1.00025
SAR1B secretion associated, Ras related GTPase 1B 0.99928
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.991162
SEC63 SEC63 homolog (S. cerevisiae) 0.984888
TM7SF2 transmembrane 7 superfamily member 2 0.981834
HIST2H4A histone cluster 2, H4a 0.976238
DHCR24 24-dehydrocholesterol reductase 0.968998
MRPL20 mitochondrial ribosomal protein L20 0.966347
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.964936
ADPGK ADP-dependent glucokinase 0.960553
MAP2K3 mitogen-activated protein kinase kinase 3 0.960509
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.95962
ABAT 4-aminobutyrate aminotransferase 0.95357
SETD5 SET domain containing 5 0.947118
PXN paxillin 0.943199
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough 0.94229
SH2D4A SH2 domain containing 4A 0.941789
JUP junction plakoglobin 0.941592
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.941376
SPINK1 serine peptidase inhibitor, Kazal type 1 0.940341
PGRMC1 progesterone receptor membrane component 1 0.939036
TDO2 tryptophan 2,3-dioxygenase 0.93588
XPO6 exportin 6 0.93442
MTX2 metaxin 2 0.932453
RFC1 replication factor C (activator 1) 1, 145kDa 0.932066
MRPL41 mitochondrial ribosomal protein L41 0.927977
SERINC1 serine incorporator 1 0.927136
DCXR dicarbonyl/L-xylulose reductase 0.926818
CCNC cyclin C 0.926562
GLRX3 glutaredoxin 3 0.92182
THRSP thyroid hormone responsive 0.919177
CBFB core-binding factor, beta subunit 0.917754
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 0.917636
CISD1 CDGSH iron sulfur domain 1 0.909855
TIMP2 TIMP metallopeptidase inhibitor 2 0.909025
ARL3 ADP-ribosylation factor-like 3 0.907601
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 0.905937
RPS14 ribosomal protein S14 0.905529
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.90067
ERCC6 excision repair cross-complementation group 6 0.899206
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.897895
CA5A carbonic anhydrase VA, mitochondrial 0.894944
DERL1 derlin 1 0.891883
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.890962
MCTS1 malignant T cell amplified sequence 1 0.890122
PLA2G16 phospholipase A2, group XVI 0.888464
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.886999
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 0.883927
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 0.876484
RPL31 ribosomal protein L31 0.87614
CYB5A cytochrome b5 type A (microsomal) 0.873687
IMPAD1 inositol monophosphatase domain containing 1 0.873181
ZFYVE27 zinc finger, FYVE domain containing 27 0.872198
COX2 0.870855
TAS2R1 taste receptor, type 2, member 1 0.870762
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.870352
COMMD3 COMM domain containing 3 0.868906
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 0.868173
ARG1 arginase 1 0.868032
RFK riboflavin kinase 0.867645
EMC6 ER membrane protein complex subunit 6 0.866806
PRODH2 proline dehydrogenase (oxidase) 2 0.864421
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.86167
UBAC1 UBA domain containing 1 0.861164
CTSF cathepsin F 0.859808
DCTN1 dynactin 1 0.859718
RPS6 ribosomal protein S6 0.856152
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.851859
COPS6 COP9 signalosome subunit 6 0.848639
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 0.84689
RPL27A ribosomal protein L27a 0.844119
PRDX3 peroxiredoxin 3 0.84272
RAB18 RAB18, member RAS oncogene family 0.841182
TSPYL1 TSPY-like 1 0.839462
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.839229
SYAP1 synapse associated protein 1 0.837683
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.836754
SEPT7 septin 7 0.832168
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.83187
DDB2 damage-specific DNA binding protein 2, 48kDa 0.831576
CCDC28A coiled-coil domain containing 28A 0.83148
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.83113
CMC2 C-x(9)-C motif containing 2 0.830661
TRA2A transformer 2 alpha homolog (Drosophila) 0.830459
SOCS5 suppressor of cytokine signaling 5 0.829869
PAH phenylalanine hydroxylase 0.828726
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.826391
ISCU iron-sulfur cluster assembly enzyme 0.822178
ACMSD aminocarboxymuconate semialdehyde decarboxylase 0.818013
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.817019
RBM7 RNA binding motif protein 7 0.816255

decreased expression

Symbol Name Standardized Value
GLTP glycolipid transfer protein -4.74416
SBF1 SET binding factor 1 -4.21765
GLYCTK glycerate kinase -4.10274
KDM5B lysine (K)-specific demethylase 5B -3.56499
CLDN2 claudin 2 -3.47582
GTF2I general transcription factor IIi -3.23907
NDRG1 N-myc downstream regulated 1 -3.21747
CAMTA1 calmodulin binding transcription activator 1 -3.1824
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -3.04624
SEC13 SEC13 homolog (S. cerevisiae) -3.00499
SYTL4 synaptotagmin-like 4 -3.00228
CACUL1 CDK2-associated, cullin domain 1 -2.95128
EDNRA endothelin receptor type A -2.86085
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.74557
CTF1 cardiotrophin 1 -2.70707
SORBS2 sorbin and SH3 domain containing 2 -2.70118
RPL17 ribosomal protein L17 -2.66401
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.63403
OXA1L oxidase (cytochrome c) assembly 1-like -2.63396
BLCAP bladder cancer associated protein -2.62055
INSIG2 insulin induced gene 2 -2.57601
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.56648
EIF3G eukaryotic translation initiation factor 3, subunit G -2.54978
PFKP phosphofructokinase, platelet -2.50491
CPT2 carnitine palmitoyltransferase 2 -2.50252
MRPS9 mitochondrial ribosomal protein S9 -2.4168
PTER phosphotriesterase related -2.39452
ADD3 adducin 3 (gamma) -2.38541
CD300A CD300a molecule -2.36974
GZMK granzyme K (granzyme 3; tryptase II) -2.33943
SPTBN1 spectrin, beta, non-erythrocytic 1 -2.32413
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin -2.30498
STX7 syntaxin 7 -2.29423
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -2.28585
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.24996
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -2.18227
CSK c-src tyrosine kinase -2.16505
MAP2K7 mitogen-activated protein kinase kinase 7 -2.14705
MAT2A methionine adenosyltransferase II, alpha -2.1322
TBRG1 transforming growth factor beta regulator 1 -2.08001
HDLBP high density lipoprotein binding protein -2.07142
ARRDC1 arrestin domain containing 1 -2.05944
EXOC4 exocyst complex component 4 -2.04099
NCOR1 nuclear receptor corepressor 1 -2.02562
CRYBG3 beta-gamma crystallin domain containing 3 -2.02339
ADIPOR2 adiponectin receptor 2 -2.0181
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.00555
CDK19 cyclin-dependent kinase 19 -1.99987
WDR41 WD repeat domain 41 -1.98509
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -1.97868
MAGED1 melanoma antigen family D1 -1.95796
LSM12 LSM12 homolog (S. cerevisiae) -1.93266
MYO1D myosin ID -1.92954
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -1.92199
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.9012
HYOU1 hypoxia up-regulated 1 -1.89496
ZCCHC12 zinc finger, CCHC domain containing 12 -1.89351
TRABD TraB domain containing -1.87966
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.87598
EFHD2 EF-hand domain family, member D2 -1.85914
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -1.83656
CSNK1D casein kinase 1, delta -1.83142
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -1.80213
XPC xeroderma pigmentosum, complementation group C -1.80148
CHERP calcium homeostasis endoplasmic reticulum protein -1.79119
MYOZ1 myozenin 1 -1.78337
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -1.75393
TXNRD1 thioredoxin reductase 1 -1.74756
MRPS18B mitochondrial ribosomal protein S18B -1.74564
MAP2K1 mitogen-activated protein kinase kinase 1 -1.74419
ADCY6 adenylate cyclase 6 -1.73624
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -1.731
RAB2B RAB2B, member RAS oncogene family -1.72066
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -1.70778
SEC62 SEC62 homolog (S. cerevisiae) -1.70238
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -1.69811
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -1.6928
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -1.68624
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.6859
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -1.68308
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -1.68219
TMEM147 transmembrane protein 147 -1.68086
CLMP CXADR-like membrane protein -1.65991
FCF1 FCF1 rRNA-processing protein -1.64417
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -1.64339
CXCL10 chemokine (C-X-C motif) ligand 10 -1.6432
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.64284
INSL3 insulin-like 3 (Leydig cell) -1.64187
EIF1AD eukaryotic translation initiation factor 1A domain containing -1.63776
SNRK SNF related kinase -1.63737
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -1.62528
UROD uroporphyrinogen decarboxylase -1.60831
RPL7L1 ribosomal protein L7-like 1 -1.58934
MAK male germ cell-associated kinase -1.58139
TSEN34 TSEN34 tRNA splicing endonuclease subunit -1.57931
AUH AU RNA binding protein/enoyl-CoA hydratase -1.57741
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.57481
RPL18A ribosomal protein L18a -1.56659
KIDINS220 kinase D-interacting substrate, 220kDa -1.56181
SEC11C SEC11 homolog C (S. cerevisiae) -1.54383
GRIA4 glutamate receptor, ionotropic, AMPA 4 -1.53946
PCGF5 polycomb group ring finger 5 -1.53858
DNLZ DNL-type zinc finger -1.53841
YPEL3 yippee-like 3 (Drosophila) -1.53584
PARL presenilin associated, rhomboid-like -1.52641
ECI1 enoyl-CoA delta isomerase 1 -1.51601
EPHA2 EPH receptor A2 -1.51297
FDX1L ferredoxin 1-like -1.51137
KRT18 keratin 18, type I -1.49768
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.49744
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -1.49647
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -1.49388
ANXA6 annexin A6 -1.49328
APEH acylaminoacyl-peptide hydrolase -1.48682
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.48467
AGA aspartylglucosaminidase -1.48381
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -1.46016
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.45224
ACTN4 actinin, alpha 4 -1.45001
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -1.44799
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -1.44541
UBN1 ubinuclein 1 -1.43917
UBXN1 UBX domain protein 1 -1.43499
VCL vinculin -1.42748
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -1.4263
CDC42SE1 CDC42 small effector 1 -1.40978
CCL22 chemokine (C-C motif) ligand 22 -1.39792
WDTC1 WD and tetratricopeptide repeats 1 -1.39048
PTN pleiotrophin -1.38519
CDCA8 cell division cycle associated 8 -1.38097
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -1.37504
NEO1 neogenin 1 -1.36598
ADCK5 aarF domain containing kinase 5 -1.3575
COPG1 coatomer protein complex, subunit gamma 1 -1.35655
PTK2B protein tyrosine kinase 2 beta -1.35607
KXD1 KxDL motif containing 1 -1.35559
GSTM1 glutathione S-transferase mu 1 -1.3549
TSPYL2 TSPY-like 2 -1.35468
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.3543
COMMD8 COMM domain containing 8 -1.35366
ELF2 E74-like factor 2 (ets domain transcription factor) -1.3497
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.34112
SPARCL1 SPARC-like 1 (hevin) -1.33221
GALR3 galanin receptor 3 -1.33217
FGF7 fibroblast growth factor 7 -1.32445
FLOT2 flotillin 2 -1.31788
ACOT4 acyl-CoA thioesterase 4 -1.31446
UPK3BL uroplakin 3B-like -1.30671
C11ORF73 chromosome 11 open reading frame 73 -1.30595
RNF213 ring finger protein 213 -1.3052
APMAP adipocyte plasma membrane associated protein -1.3026
KYNU kynureninase -1.29462
MFN2 mitofusin 2 -1.28433
HSF1 heat shock transcription factor 1 -1.28316
GCLM glutamate-cysteine ligase, modifier subunit -1.28301
LRRC59 leucine rich repeat containing 59 -1.27737
SHROOM1 shroom family member 1 -1.2763
SHARPIN SHANK-associated RH domain interactor -1.27609
AJUBA ajuba LIM protein -1.2702
NEURL4 neuralized E3 ubiquitin protein ligase 4 -1.27019
AARS alanyl-tRNA synthetase -1.2637
MIA melanoma inhibitory activity -1.26187
MRPS30 mitochondrial ribosomal protein S30 -1.25976
HBP1 HMG-box transcription factor 1 -1.25036
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -1.24772
MED28 mediator complex subunit 28 -1.24393
MED1 mediator complex subunit 1 -1.23892
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -1.23732
ZFYVE26 zinc finger, FYVE domain containing 26 -1.23154
STX2 syntaxin 2 -1.22646
FDXR ferredoxin reductase -1.2147
ADAMTSL4 ADAMTS-like 4 -1.20399
ABHD16A abhydrolase domain containing 16A -1.20341
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -1.20191
ATRNL1 attractin-like 1 -1.19973
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.19498
INPP5K inositol polyphosphate-5-phosphatase K -1.19369
RPS19 ribosomal protein S19 -1.19265
PARP2 poly (ADP-ribose) polymerase 2 -1.19043
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -1.18986
ARL5A ADP-ribosylation factor-like 5A -1.17792
CD37 CD37 molecule -1.1758
RCC2 regulator of chromosome condensation 2 -1.17061
PRDX5 peroxiredoxin 5 -1.16835
INO80C INO80 complex subunit C -1.16485
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.16132
NHLRC3 NHL repeat containing 3 -1.16118
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.16096
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -1.15876
ZNF226 zinc finger protein 226 -1.15219
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -1.15092
NFYC nuclear transcription factor Y, gamma -1.15056
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -1.14267
PFDN6 prefoldin subunit 6 -1.14178
GOLGA2 golgin A2 -1.14124
EIF2D eukaryotic translation initiation factor 2D -1.13712
NR2C2AP nuclear receptor 2C2-associated protein -1.12354
DPP4 dipeptidyl-peptidase 4 -1.11861
XPO7 exportin 7 -1.11579
RANBP10 RAN binding protein 10 -1.1127
WDR77 WD repeat domain 77 -1.11166
FAM117A family with sequence similarity 117, member A -1.10145
CHMP7 charged multivesicular body protein 7 -1.09203
NR1H2 nuclear receptor subfamily 1, group H, member 2 -1.0854
MCOLN1 mucolipin 1 -1.0838
ZNRD1 zinc ribbon domain containing 1 -1.07394
COPS8 COP9 signalosome subunit 8 -1.07185
HTRA2 HtrA serine peptidase 2 -1.07153
RNASEK ribonuclease, RNase K -1.07107
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.06977
BTBD1 BTB (POZ) domain containing 1 -1.06554
CDC37 cell division cycle 37 -1.06335
PRR14L proline rich 14-like -1.05487
GSTM5 glutathione S-transferase mu 5 -1.0545
AP2M1 adaptor-related protein complex 2, mu 1 subunit -1.04772
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -1.04629
XCL1 chemokine (C motif) ligand 1 -1.04499
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.04221
SORD sorbitol dehydrogenase -1.03859
BPHL biphenyl hydrolase-like (serine hydrolase) -1.03203
TBX2 T-box 2 -1.03121
SURF4 surfeit 4 -1.02705
ACSS1 acyl-CoA synthetase short-chain family member 1 -1.02505
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -1.02474
BTF3 basic transcription factor 3 -1.02303
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -1.02283
OSBP oxysterol binding protein -1.01903
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -1.01689
GATAD2A GATA zinc finger domain containing 2A -1.01175
NOP10 NOP10 ribonucleoprotein -1.00927
CTPS2 CTP synthase 2 -1.00228
CLPTM1L CLPTM1-like -1.00076
SHANK3 SH3 and multiple ankyrin repeat domains 3 -1.00075
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.998324
USP15 ubiquitin specific peptidase 15 -0.99681
RBPMS2 RNA binding protein with multiple splicing 2 -0.993732
BRIX1 BRX1, biogenesis of ribosomes -0.991872
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.990122
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -0.987321
ZNF318 zinc finger protein 318 -0.986505
PALMD palmdelphin -0.983841
KIFAP3 kinesin-associated protein 3 -0.982082
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.979547
SMAD7 SMAD family member 7 -0.976236
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.975025
WDR1 WD repeat domain 1 -0.974401
FIBP fibroblast growth factor (acidic) intracellular binding protein -0.970748
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -0.969424
NEK9 NIMA-related kinase 9 -0.966083
TCP11L2 t-complex 11, testis-specific-like 2 -0.964964
ABT1 activator of basal transcription 1 -0.964878
MAP2K5 mitogen-activated protein kinase kinase 5 -0.958878
CTNND1 catenin (cadherin-associated protein), delta 1 -0.958834
MAP6D1 MAP6 domain containing 1 -0.958581
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.956898
TMEM199 transmembrane protein 199 -0.95677
CXXC1 CXXC finger protein 1 -0.955267
RNF26 ring finger protein 26 -0.954118
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -0.949411
ETFDH electron-transferring-flavoprotein dehydrogenase -0.949091
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 -0.947181
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -0.946207
RAI14 retinoic acid induced 14 -0.944389
TALDO1 transaldolase 1 -0.940523
TRAPPC9 trafficking protein particle complex 9 -0.93995
LPIN3 lipin 3 -0.931164
FKBP4 FK506 binding protein 4, 59kDa -0.926654
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 -0.92638
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -0.922239
CPNE1 copine I -0.920972
ZYX zyxin -0.920552
STRAP serine/threonine kinase receptor associated protein -0.91905
GBA glucosidase, beta, acid -0.918816
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.915628
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -0.915052
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa -0.909583
TM2D2 TM2 domain containing 2 -0.904349
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -0.903965
MSN moesin -0.90198
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.901681
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.900146
MRPL42 mitochondrial ribosomal protein L42 -0.89956
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -0.898629
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 -0.892359
IFI30 interferon, gamma-inducible protein 30 -0.892342
NDNL2 necdin-like 2 -0.889906
SEC24C SEC24 family member C -0.888208
ITGA6 integrin, alpha 6 -0.888001
TNNT1 troponin T type 1 (skeletal, slow) -0.885227
OMP olfactory marker protein -0.883199
AGTPBP1 ATP/GTP binding protein 1 -0.881898
ERGIC3 ERGIC and golgi 3 -0.880973
SEC23B Sec23 homolog B (S. cerevisiae) -0.877468
RPS23 ribosomal protein S23 -0.876928
CIDEA cell death-inducing DFFA-like effector a -0.876695
SAYSD1 SAYSVFN motif domain containing 1 -0.876211
EPOR erythropoietin receptor -0.874761
ANXA4 annexin A4 -0.87299
TMED4 transmembrane emp24 protein transport domain containing 4 -0.869966
KAT7 K(lysine) acetyltransferase 7 -0.864346