Sepsis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Systemic inflammatory response to infection. (Human Phenotype Ontology, HP_0100806)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018805
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Genes

566 genes/proteins associated with the disease Sepsis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CXCR2 chemokine (C-X-C motif) receptor 2 2.88009
HMGB1 high mobility group box 1 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
LTA lymphotoxin alpha 2.88009
LBP lipopolysaccharide binding protein 2.88009
TLR4 toll-like receptor 4 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
MMP9 matrix metallopeptidase 9 2.88009
TNF tumor necrosis factor 2.88009
IFNA2 interferon, alpha 2 2.88009
MAPK3 mitogen-activated protein kinase 3 2.88009
ADM adrenomedullin 2.88009
IL10 interleukin 10 2.88009
ANGPT1 angiopoietin 1 2.88009
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.88009
MAPK1 mitogen-activated protein kinase 1 2.88009
IFNG interferon, gamma 2.88009
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2.88009
CSF3 colony stimulating factor 3 (granulocyte) 2.88009
IL1B interleukin 1, beta 2.34592
IL6 interleukin 6 2.25887
BAX BCL2-associated X protein 2.23816
CAT catalase 2.21747
MPO myeloperoxidase 2.17396
BCL2 B-cell CLL/lymphoma 2 2.16507
VEGFA vascular endothelial growth factor A 2.13676
JUN jun proto-oncogene 2.13622
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.13546
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.12148
FAS Fas cell surface death receptor 2.10907
CXCL8 chemokine (C-X-C motif) ligand 8 2.10263
SOD2 superoxide dismutase 2, mitochondrial 2.08787
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.08669
FASLG Fas ligand (TNF superfamily, member 6) 2.08068
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.04942
TIMP1 TIMP metallopeptidase inhibitor 1 2.02998
BCL2L1 BCL2-like 1 2.02006
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.01295
TP53 tumor protein p53 2.00884
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.0044
VCAM1 vascular cell adhesion molecule 1 1.99538
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.98683
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.98182
HMOX1 heme oxygenase 1 1.96432
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.96299
IL1A interleukin 1, alpha 1.96147
BIRC3 baculoviral IAP repeat containing 3 1.95315
ICAM1 intercellular adhesion molecule 1 1.95178
F3 coagulation factor III (thromboplastin, tissue factor) 1.94874
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.94627
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.94563
CCL2 chemokine (C-C motif) ligand 2 1.93674
IL4 interleukin 4 1.91765
STAT1 signal transducer and activator of transcription 1, 91kDa 1.91635
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.89993
PARP1 poly (ADP-ribose) polymerase 1 1.89894
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.89455
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.88869
ERBB2 erb-b2 receptor tyrosine kinase 2 1.87725
TOP2A topoisomerase (DNA) II alpha 170kDa 1.85782
IL12B interleukin 12B 1.84464
BIRC2 baculoviral IAP repeat containing 2 1.84358
FOS FBJ murine osteosarcoma viral oncogene homolog 1.84341
MAPK8 mitogen-activated protein kinase 8 1.84215
GADD45A growth arrest and DNA-damage-inducible, alpha 1.84215
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.84198
BAK1 BCL2-antagonist/killer 1 1.82185
DDIT3 DNA-damage-inducible transcript 3 1.81885
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.81036
BID BH3 interacting domain death agonist 1.80019
MMP1 matrix metallopeptidase 1 1.79484
CTGF connective tissue growth factor 1.79484
MMP3 matrix metallopeptidase 3 1.78188
EPO erythropoietin 1.78091
CDK2 cyclin-dependent kinase 2 1.78013
THBS1 thrombospondin 1 1.77859
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.77492
MCL1 myeloid cell leukemia 1 1.76888
CFLAR CASP8 and FADD-like apoptosis regulator 1.76151
CCNB1 cyclin B1 1.75738
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.7542
GPX1 glutathione peroxidase 1 1.75221
GPX3 glutathione peroxidase 3 1.74681
EDNRB endothelin receptor type B 1.74681
CXCL10 chemokine (C-X-C motif) ligand 10 1.73698
EGFR epidermal growth factor receptor 1.73598
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.73129
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.72633
SPP1 secreted phosphoprotein 1 1.72405
EGR1 early growth response 1 1.72014
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.71524
CD14 CD14 molecule 1.70947
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.69867
PRKCD protein kinase C, delta 1.6891
TYMP thymidine phosphorylase 1.67868
IGFBP3 insulin-like growth factor binding protein 3 1.66792
GSTM1 glutathione S-transferase mu 1 1.6677
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.66684
COL3A1 collagen, type III, alpha 1 1.66425
GSTP1 glutathione S-transferase pi 1 1.66274
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.65709
TRAF2 TNF receptor-associated factor 2 1.65555
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.65292
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.65249
CXCL2 chemokine (C-X-C motif) ligand 2 1.65227
SELE selectin E 1.65204
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.64752
MAPK9 mitogen-activated protein kinase 9 1.64685
NGF nerve growth factor (beta polypeptide) 1.64416
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.64123
IL2 interleukin 2 1.6381
NFE2L2 nuclear factor, erythroid 2-like 2 1.63541
S100A9 S100 calcium binding protein A9 1.63496
BTG2 BTG family, member 2 1.63384
EDN1 endothelin 1 1.63094
H2AFX H2A histone family, member X 1.62938
CD44 CD44 molecule (Indian blood group) 1.62222
COL1A1 collagen, type I, alpha 1 1.60874
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.60501
NQO1 NAD(P)H dehydrogenase, quinone 1 1.60058
PPARG peroxisome proliferator-activated receptor gamma 1.59989
CDK1 cyclin-dependent kinase 1 1.59708
CCNG1 cyclin G1 1.59288
NPPB natriuretic peptide B 1.59288
NOS1 nitric oxide synthase 1 (neuronal) 1.58865
PCNA proliferating cell nuclear antigen 1.58327
HSPB1 heat shock 27kDa protein 1 1.58303
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.57994
GSR glutathione reductase 1.57498
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.56947
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.56361
BIRC5 baculoviral IAP repeat containing 5 1.5619
FLT1 fms-related tyrosine kinase 1 1.55846
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.55427
IL18 interleukin 18 1.54232
PLAT plasminogen activator, tissue 1.54232
MGMT O-6-methylguanine-DNA methyltransferase 1.54208
FN1 fibronectin 1 1.54014
MAPK14 mitogen-activated protein kinase 14 1.53892
GJA1 gap junction protein, alpha 1, 43kDa 1.53431
C3 complement component 3 1.53431
PPARA peroxisome proliferator-activated receptor alpha 1.53308
DDIT4 DNA-damage-inducible transcript 4 1.52865
SOD1 superoxide dismutase 1, soluble 1.52767
GUSB glucuronidase, beta 1.52338
CTSD cathepsin D 1.52262
RB1 retinoblastoma 1 1.52086
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.51886
MMP2 matrix metallopeptidase 2 1.51506
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.51506
CP ceruloplasmin (ferroxidase) 1.5113
ODC1 ornithine decarboxylase 1 1.51055
APAF1 apoptotic peptidase activating factor 1 1.50953
DUSP1 dual specificity phosphatase 1 1.50903
PLAU plasminogen activator, urokinase 1.50574
TYMS thymidylate synthetase 1.49864
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.49558
BUB3 BUB3 mitotic checkpoint protein 1.48376
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.47787
B2M beta-2-microglobulin 1.47686
CALCA calcitonin-related polypeptide alpha 1.47556
IL1RN interleukin 1 receptor antagonist 1.474
CHEK2 checkpoint kinase 2 1.474
CCL3 chemokine (C-C motif) ligand 3 1.47374
ALB albumin 1.46648
IGF1 insulin-like growth factor 1 (somatomedin C) 1.46488
MMP13 matrix metallopeptidase 13 1.45723
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.45537
CXCR4 chemokine (C-X-C motif) receptor 4 1.45511
SPON1 spondin 1, extracellular matrix protein 1.45431
ATF3 activating transcription factor 3 1.45273
PGD phosphogluconate dehydrogenase 1.45273
TUBB tubulin, beta class I 1.4522
IL12A interleukin 12A 1.45115
BAD BCL2-associated agonist of cell death 1.44872
AVP arginine vasopressin 1.44246
VIM vimentin 1.43864
NPPA natriuretic peptide A 1.43864
IGFBP5 insulin-like growth factor binding protein 5 1.43727
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.43482
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.43482
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.43184
CYCS cytochrome c, somatic 1.42669
BCL2A1 BCL2-related protein A1 1.42535
CCL5 chemokine (C-C motif) ligand 5 1.42428
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.41965
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41775
IL7 interleukin 7 1.41748
GCLC glutamate-cysteine ligase, catalytic subunit 1.41559
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.41313
CSF1 colony stimulating factor 1 (macrophage) 1.41285
S100A8 S100 calcium binding protein A8 1.41063
MYD88 myeloid differentiation primary response 88 1.4098
GSK3B glycogen synthase kinase 3 beta 1.4087
F2 coagulation factor II (thrombin) 1.40457
BBC3 BCL2 binding component 3 1.40373
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.40204
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.39479
GADD45B growth arrest and DNA-damage-inducible, beta 1.39226
CCNG2 cyclin G2 1.3917
S100A4 S100 calcium binding protein A4 1.38298
EGF epidermal growth factor 1.38213
PDE4B phosphodiesterase 4B, cAMP-specific 1.38015
ANXA1 annexin A1 1.37902
PRKCA protein kinase C, alpha 1.37761
ERCC1 excision repair cross-complementation group 1 1.37446
MAP2K1 mitogen-activated protein kinase kinase 1 1.36735
MKI67 marker of proliferation Ki-67 1.36562
NRP1 neuropilin 1 1.36332
HSPA8 heat shock 70kDa protein 8 1.36218
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.36104
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.35502
CD40LG CD40 ligand 1.35415
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.35299
G6PD glucose-6-phosphate dehydrogenase 1.35069
MBP myelin basic protein 1.34983
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.34869
E2F1 E2F transcription factor 1 1.34723
ERBB4 erb-b2 receptor tyrosine kinase 4 1.34489
SELL selectin L 1.34343
LCN2 lipocalin 2 1.34314
SP1 Sp1 transcription factor 1.34111
CLU clusterin 1.34082
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.34053
SESN1 sestrin 1 1.33995
CTSL cathepsin L 1.33938
FGF2 fibroblast growth factor 2 (basic) 1.33909
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.33731
CTSS cathepsin S 1.33642
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.33464
FOXO3 forkhead box O3 1.33434
POMC proopiomelanocortin 1.3311
KLF6 Kruppel-like factor 6 1.32667
GADD45G growth arrest and DNA-damage-inducible, gamma 1.32667
ASS1 argininosuccinate synthase 1 1.32637
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.32518
TIMP2 TIMP metallopeptidase inhibitor 2 1.32518
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.3231
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.31956
CCND1 cyclin D1 1.31867
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.31566
GFRA1 GDNF family receptor alpha 1 1.31536
CXCL12 chemokine (C-X-C motif) ligand 12 1.31387
LEP leptin 1.31178
TMSB4X thymosin beta 4, X-linked 1.31089
HSPA2 heat shock 70kDa protein 2 1.30971
TH tyrosine hydroxylase 1.30788
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.30666
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.30635
HSPA1A heat shock 70kDa protein 1A 1.30635
TAC1 tachykinin, precursor 1 1.30635
CD40 CD40 molecule, TNF receptor superfamily member 5 1.30482
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.30482
THBD thrombomodulin 1.30329
TUBA4A tubulin, alpha 4a 1.30177
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.30056
POR P450 (cytochrome) oxidoreductase 1.30026
TIMP3 TIMP metallopeptidase inhibitor 3 1.29996
GSTA4 glutathione S-transferase alpha 4 1.29875
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.29781
ACKR3 atypical chemokine receptor 3 1.29719
MARCKS myristoylated alanine-rich protein kinase C substrate 1.29379
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.28241
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.2818
CCNA2 cyclin A2 1.28088
BDKRB1 bradykinin receptor B1 1.27564
CRH corticotropin releasing hormone 1.27471
GCLM glutamate-cysteine ligase, modifier subunit 1.27224
RRM2 ribonucleotide reductase M2 1.27224
C1QA complement component 1, q subcomponent, A chain 1.27162
ADD3 adducin 3 (gamma) 1.27162
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.27162
S100P S100 calcium binding protein P 1.27162
TXNIP thioredoxin interacting protein 1.27009
SRXN1 sulfiredoxin 1 1.27009
GHR growth hormone receptor 1.26978
CCNB2 cyclin B2 1.26794
TFPI2 tissue factor pathway inhibitor 2 1.26763
GAMT guanidinoacetate N-methyltransferase 1.26763
DIABLO diablo, IAP-binding mitochondrial protein 1.267
FSHB follicle stimulating hormone, beta polypeptide 1.26483
AXL AXL receptor tyrosine kinase 1.26359
MAP2K3 mitogen-activated protein kinase kinase 3 1.2596
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.2596
INSIG1 insulin induced gene 1 1.25929
HMGB2 high mobility group box 2 1.25838
KLF4 Kruppel-like factor 4 (gut) 1.25838
CDKN2A cyclin-dependent kinase inhibitor 2A 1.25807
TGFB2 transforming growth factor, beta 2 1.25745
HSPA1B heat shock 70kDa protein 1B 1.25745
FOXO1 forkhead box O1 1.25557
THY1 Thy-1 cell surface antigen 1.25557
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.25307
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.25276
S100A11 S100 calcium binding protein A11 1.25183
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.25183
CD36 CD36 molecule (thrombospondin receptor) 1.25152
SOCS3 suppressor of cytokine signaling 3 1.2509
GDF15 growth differentiation factor 15 1.24812
TANK TRAF family member-associated NFKB activator 1.24718
SGK1 serum/glucocorticoid regulated kinase 1 1.24496
UBE2C ubiquitin-conjugating enzyme E2C 1.24465
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.24275
INS insulin 1.23962
XDH xanthine dehydrogenase 1.2368
CD274 CD274 molecule 1.23584
INHBA inhibin, beta A 1.23137
CHEK1 checkpoint kinase 1 1.23074
TFRC transferrin receptor 1.23042
PTX3 pentraxin 3, long 1.22948
PRLR prolactin receptor 1.22884
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.22727
AQP1 aquaporin 1 (Colton blood group) 1.22632
TAGLN transgelin 1.22632
NES nestin 1.22599
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.22599
CASP12 caspase 12 (gene/pseudogene) 1.22339
CAV1 caveolin 1, caveolae protein, 22kDa 1.22274
CTH cystathionine gamma-lyase 1.2208
FANCG Fanconi anemia, complementation group G 1.21984
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.21984
PRC1 protein regulator of cytokinesis 1 1.21887
IGF1R insulin-like growth factor 1 receptor 1.21695
FABP4 fatty acid binding protein 4, adipocyte 1.21501
RIPK2 receptor-interacting serine-threonine kinase 2 1.21468
DHFR dihydrofolate reductase 1.21337
RGS4 regulator of G-protein signaling 4 1.21173
E2F3 E2F transcription factor 3 1.20946
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.20913
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.20816
COL1A2 collagen, type I, alpha 2 1.20526
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.20163
PPARD peroxisome proliferator-activated receptor delta 1.20097
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.19802
LHB luteinizing hormone beta polypeptide 1.19509
IL13 interleukin 13 1.19412
GFAP glial fibrillary acidic protein 1.19412
FYN FYN proto-oncogene, Src family tyrosine kinase 1.19146
IFNB1 interferon, beta 1, fibroblast 1.19146
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.19113
CALR calreticulin 1.19113
SRGN serglycin 1.18948
TRIM2 tripartite motif containing 2 1.18948
CCNE1 cyclin E1 1.18915
CAPN2 calpain 2, (m/II) large subunit 1.18849
ACTA2 actin, alpha 2, smooth muscle, aorta 1.18783
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.18652
ERBB3 erb-b2 receptor tyrosine kinase 3 1.18521
HAMP hepcidin antimicrobial peptide 1.18521
IGFBP4 insulin-like growth factor binding protein 4 1.18521
NBN nibrin 1.18489
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.18456
PRKCE protein kinase C, epsilon 1.18424
EP300 E1A binding protein p300 1.18193
PRKCB protein kinase C, beta 1.18193
MT1A metallothionein 1A 1.18126
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.17893
SMAD3 SMAD family member 3 1.17728
RXRA retinoid X receptor, alpha 1.17596
PTK2 protein tyrosine kinase 2 1.17497
SIRT1 sirtuin 1 1.17431
CLDN1 claudin 1 1.17268
KRT18 keratin 18, type I 1.17268
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.17134
BCL2L2 BCL2-like 2 1.17101
SAA3P serum amyloid A3 pseudogene 1.17101
CYBB cytochrome b-245, beta polypeptide 1.17034
PER2 period circadian clock 2 1.16967
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.16967
ANXA5 annexin A5 1.16833
IFITM1 interferon induced transmembrane protein 1 1.16666
TLR2 toll-like receptor 2 1.16368
TGM2 transglutaminase 2 1.16368
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.16335
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.16335
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.16203
KEAP1 kelch-like ECH-associated protein 1 1.1617
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.1617
DCN decorin 1.16035
BTG3 BTG family, member 3 1.15797
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.15492
IRS1 insulin receptor substrate 1 1.15492
CYR61 cysteine-rich, angiogenic inducer, 61 1.15492
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.15458
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.1529
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.15189
VLDLR very low density lipoprotein receptor 1.14885
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.14575
CXCL5 chemokine (C-X-C motif) ligand 5 1.14575
UNG uracil-DNA glycosylase 1.14575
CDKN3 cyclin-dependent kinase inhibitor 3 1.14575
JUNB jun B proto-oncogene 1.14336
CDC25B cell division cycle 25B 1.14302
BDNF brain-derived neurotrophic factor 1.14302
NPY neuropeptide Y 1.142
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.14098
IL5 interleukin 5 1.13862
PTEN phosphatase and tensin homolog 1.13862
CPE carboxypeptidase E 1.13689
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.13586
SMAD2 SMAD family member 2 1.13449
GEM GTP binding protein overexpressed in skeletal muscle 1.13313
POSTN periostin, osteoblast specific factor 1.13313
BTG1 B-cell translocation gene 1, anti-proliferative 1.13177
BECN1 beclin 1, autophagy related 1.13177
IL3 interleukin 3 1.12906
IL23A interleukin 23, alpha subunit p19 1.12906
CRYAB crystallin, alpha B 1.12771
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.12634
ZFP36L1 ZFP36 ring finger protein-like 1 1.1253
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.12219
TNNI3 troponin I type 3 (cardiac) 1.12151
ALAS2 5'-aminolevulinate synthase 2 1.12151
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.12151
IFRD1 interferon-related developmental regulator 1 1.12082
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.12082
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.12082
PLAUR plasminogen activator, urokinase receptor 1.11945
MSMO1 methylsterol monooxygenase 1 1.11809
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.11775
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.11741
DPYD dihydropyrimidine dehydrogenase 1.11571
CTSB cathepsin B 1.11571
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.11571
SOCS1 suppressor of cytokine signaling 1 1.11396
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.1129
ATF4 activating transcription factor 4 1.11186
BCL2L12 BCL2-like 12 (proline rich) 1.11116
ACTB actin, beta 1.10977
CPT1A carnitine palmitoyltransferase 1A (liver) 1.10769
ATM ATM serine/threonine kinase 1.10769
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.10769
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.10282
FHL1 four and a half LIM domains 1 1.10282
VCAN versican 1.09892
CDK4 cyclin-dependent kinase 4 1.09681
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.09541
OAT ornithine aminotransferase 1.09506
PRKCI protein kinase C, iota 1.09436
BMP4 bone morphogenetic protein 4 1.09262
FOSL1 FOS-like antigen 1 1.09262
RGS16 regulator of G-protein signaling 16 1.0919
GPR176 G protein-coupled receptor 176 1.09047
FAM171A1 family with sequence similarity 171, member A1 1.09047
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.09011
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.08868
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.08868
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.08513
STAT5A signal transducer and activator of transcription 5A 1.08478
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.08337
RRAS related RAS viral (r-ras) oncogene homolog 1.08337
CCL7 chemokine (C-C motif) ligand 7 1.08266
KLF2 Kruppel-like factor 2 1.08161
AOX1 aldehyde oxidase 1 1.08161
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.08161
CD86 CD86 molecule 1.08161
ISG15 ISG15 ubiquitin-like modifier 1.08161
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.08091
PRNP prion protein 1.08019
ADA adenosine deaminase 1.07804
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.07804
SEPHS2 selenophosphate synthetase 2 1.07804
CREBBP CREB binding protein 1.07768
ERRFI1 ERBB receptor feedback inhibitor 1 1.07482
GBP1 guanylate binding protein 1, interferon-inducible 1.07305
VWF von Willebrand factor 1.07128
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.07128
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.07128
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.07128
HBEGF heparin-binding EGF-like growth factor 1.07093
CCL20 chemokine (C-C motif) ligand 20 1.07093
REN renin 1.07057
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.07057
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.06844
EPCAM epithelial cell adhesion molecule 1.06808
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.06808
PRL prolactin 1.06771
HDAC4 histone deacetylase 4 1.06771
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.06698
ALOX5 arachidonate 5-lipoxygenase 1.06515
ANXA4 annexin A4 1.06479
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.06261
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.06261
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.06188
MT2A metallothionein 2A 1.06188
TFAM transcription factor A, mitochondrial 1.06152
CD83 CD83 molecule 1.05828
CCL4 chemokine (C-C motif) ligand 4 1.05828
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.05828
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.05793
FANCI Fanconi anemia, complementation group I 1.05793
RAD51 RAD51 recombinase 1.05685
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.05648
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.05498
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.05498
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.05461
OSBPL10 oxysterol binding protein-like 10 1.05423
DBF4 DBF4 zinc finger 1.05274
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.05274
TAT tyrosine aminotransferase 1.052
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.04978
RHOA ras homolog family member A 1.04978
ANXA2 annexin A2 1.04978
RARA retinoic acid receptor, alpha 1.04978
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.04868
PLA1A phospholipase A1 member A 1.04794
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.04794
RGS1 regulator of G-protein signaling 1 1.04794
DUSP2 dual specificity phosphatase 2 1.04794
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.04757
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.04757
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.04574
RBM17 RNA binding motif protein 17 1.04574
FOSL2 FOS-like antigen 2 1.04574
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.04538
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.04538
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.04538
KNG1 kininogen 1 1.04538
GSTA3 glutathione S-transferase alpha 3 1.04465
JAK2 Janus kinase 2 1.04314
CHUK conserved helix-loop-helix ubiquitous kinase 1.04314
COL4A2 collagen, type IV, alpha 2 1.04314
KAT2B K(lysine) acetyltransferase 2B 1.04314
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.04088
COL4A1 collagen, type IV, alpha 1 1.03939
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.03864
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.03864
APLN apelin 1.03864
EMP3 epithelial membrane protein 3 1.03864
APP amyloid beta (A4) precursor protein 1.03827
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.03641
SESN2 sestrin 2 1.03641
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.03419
TP53I3 tumor protein p53 inducible protein 3 1.03382
HADH hydroxyacyl-CoA dehydrogenase 1.03308
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.03235
NCF2 neutrophil cytosolic factor 2 1.03046
PMP22 peripheral myelin protein 22 1.03009
ECH1 enoyl CoA hydratase 1, peroxisomal 1.03009
ANGPTL4 angiopoietin-like 4 1.03009
BLM Bloom syndrome, RecQ helicase-like 1.02933
CD8A CD8a molecule 1.02933
CREB1 cAMP responsive element binding protein 1 1.02821
LTF lactotransferrin 1.02746
CD38 CD38 molecule 1.02708
CCND3 cyclin D3 1.02559
EPOR erythropoietin receptor 1.02485
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.02485
JAK1 Janus kinase 1 1.02447
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.02447
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.02447
MGST1 microsomal glutathione S-transferase 1 1.02373
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.02299
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.01966
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.01739
BIRC7 baculoviral IAP repeat containing 7 1.01663
CD24 CD24 molecule 1.01625
TPI1 triosephosphate isomerase 1 1.01549
BRCA1 breast cancer 1, early onset 1.01512
METRN meteorin, glial cell differentiation regulator 1.01437
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.01212
MELK maternal embryonic leucine zipper kinase 1.01174
MAOA monoamine oxidase A 1.01137
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.01099